Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.6.3.44 (P-glycoprotein)
13,344 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein P-glycoprotein 13241 MDR1 1890 ATP 1303 ABCB1 1041 Sep 918 P-gp 779 Mol 767 breast cancer resistance protein 717 ATP-binding cassette 716 ATPase 688 cytochrome P450 648 multidrug resistance-associated protein 493 mdr1 493 CYP3A4 462 MRP1 446 ADR 390 ABC 363 ABCG2 358 BCRP 345 ABCC1 335 ABC transporter 295 CYP3A 266 MRP2 261 MRP 251 p53 240 multidrug resistance protein 235 xenobiotic 192 gut 190 Bcl-2 185 membrane protein 163 caspase-3 153 glycoprotein 152 multidrug resistance protein 1 135 PK1 133 polypeptide 129 GSH 126 tyrosine kinase 116 calcium channel 108 cytochrome 108 colon carcinoma 106 more...

Disease cancer 3963 tumor 2070 leukemia 699 breast cancer 677 MCF 531 carcinoma 400 acute myeloid leukemia 301 lymphoma 221 epilepsy 216 hepatocellular carcinoma 216 adenocarcinoma 210 CEM 205 HIV 199 lung cancer 176 tumor growth 174 Alzheimer's disease 144 ovarian cancer 135 Leukemia 132 GSH 126 multiple myeloma 122 chronic myeloid leukemia 116 acute lymphoblastic leukemia 116 melanoma 112 colon cancer 108 epithelial ovarian cancer 103 immunodeficiency 98 osteosarcoma 93 glioma 91 lung carcinoma 85 metastases 84 colorectal cancer 80 sarcoma 76 glioblastoma 73 gastric cancer 73 non-small cell lung cancer 73 depression 71 small cell lung cancer 69 neuroblastoma 68 prostate cancer 65 acute leukemia 65 more...

Symptom seizures 113 pain 50 diarrhea 44 analgesia 31 nausea 25 starvation 21 vomiting 18 constipation 15 anesthesia 12 headache 11 ataxia 9 angina 8 dizziness 8 sleepiness 7 fatigue 7 nausea and vomiting 7 hypothermia 6 tremor 4 cancer pain 4 acidity 4 insomnia 4 hepatomegaly 4 anorexia 4 syncope 3 weakness 3 collapse 3 abdominal pain 3 apathy 3 functional recovery 3 lethargy 3 Welt 2 skin damage 2 arthralgia 2 cerebellar ataxia 2 hyperoxia 2 hepatosplenomegaly 2 myalgia 2 asthenia 2 agitation 2 exhaustion 2 more...

Drug ADR 390 ABC 363 Adriamycin 195 Taxol 117 ADM 113 VCR 101 VCR 93 Cremophor EL 40 CPT-11 39 Tacrolimus 38 Monit 37 CSF 34 ROS 32 Docetaxel 32 IL-2 30 Imatinib 29 lysine 28 Etoposide 27 Glutathione 25 Tariquidar 23 caffeine 23 vitamin E 23 Cardiovasc 20 MAP 20 Ketoconazole 18 TTC 17 Taxotere 17 Gleevec 17 Dermatol 16 Vitamin E 16 IFN-gamma 16 G418 15 Gefitinib 15 Leaf 14 anti-CD33 14 Gel 14 Itraconazole 13 ascorbate 13 Irinotecan 13 AZT 13 more...

Enzyme P-glycoprotein 13344 ATPase 704 MDR 590 CYP3A4 462 topoisomerase 268 topoisomerase 247 protein kinase C 174 glutathione S-transferase 167 ERK 160 mitogen-activated protein kinase 154 reverse transcriptase 127 caspase-3 122 protein kinase 98 ACS 66 catalase 57 luciferase 55 PARP 51 glutathione peroxidase 46 calcineurin 44 RNA polymerase 42 focal adhesion kinase 40 trypsin 38 UDP-glucuronosyltransferase 38 peroxidase 37 alkaline phosphatase 36 proteasome 35 thymidylate synthase 35 superoxide dismutase 35 Mg2+-ATPase 32 caspase-9 31 RNase 31 RNase 31 transcriptase 30 thromboplastin 30 asparaginase 29 glucosylceramide synthase 27 lactate dehydrogenase 27 caspase-8 25 dihydrofolate reductase 25 MEK 25 more...

Compound ATP 1303 Dec 940 DNA 763 Clin 639 MDR 590 ADR 511 MTT 330 Adriamycin 328 sodium 288 Verapamil 269 Verapamil 268 water 257 oxygen 207 PEG 207 calcium 192 Cyclosporine 156 GSH 143 GSH 143 VP-16 132 Rhodamine 123 131 glucose 125 bromide 123 sulfate 120 acetate 117 hydrogen 116 PEG 116 cysteine 103 phosphate 102 Paclitaxel 98 MDA 92 SDZ PSC 833 87 salt 83 Vinca 81 ADP 78 ADP 75 ADP 75 tyrosine 72 FK506 72 iodine 70 Digoxin 69 more...

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