Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.6.3.44 (P-glycoprotein)
 13,344 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
P-glycoprotein 13241
MDR1 1890
ATP 1303
ABCB1 1041
Sep 918
P-gp 779
Mol 767
breast cancer resistance protein 717
ATP-binding cassette 716
ATPase 688
cytochrome P450 648
mdr1 493
multidrug resistance-associated protein 493
CYP3A4 462
MRP1 446
ADR 390
ABC 363
ABCG2 358
BCRP 345
ABCC1 335
more...
Disease
cancer 3963
tumor 2070
leukemia 699
breast cancer 677
MCF 531
carcinoma 400
acute myeloid leukemia 301
lymphoma 221
hepatocellular carcinoma 216
epilepsy 216
adenocarcinoma 210
CEM 205
HIV 199
lung cancer 176
tumor growth 174
Alzheimer's disease 144
ovarian cancer 135
Leukemia 132
GSH 126
multiple myeloma 122
more...
Symptom
seizures 113
pain 50
diarrhea 44
analgesia 31
nausea 25
starvation 21
vomiting 18
constipation 15
anesthesia 12
headache 11
ataxia 9
dizziness 8
angina 8
sleepiness 7
fatigue 7
nausea and vomiting 7
hypothermia 6
insomnia 4
tremor 4
acidity 4
more...
Drug
ADR 390
ABC 363
Adriamycin 195
Taxol 117
ADM 113
VCR 101
VCR 93
Cremophor EL 40
CPT-11 39
Tacrolimus 38
Monit 37
CSF 34
Docetaxel 32
ROS 32
IL-2 30
Imatinib 29
lysine 28
Etoposide 27
Glutathione 25
caffeine 23
more...
Enzyme
P-glycoprotein 13344
ATPase 704
MDR 590
CYP3A4 462
topoisomerase 268
topoisomerase 247
protein kinase C 174
glutathione S-transferase 167
ERK 160
mitogen-activated protein kinase 154
reverse transcriptase 127
caspase-3 122
protein kinase 98
ACS 66
catalase 57
luciferase 55
PARP 51
glutathione peroxidase 46
calcineurin 44
RNA polymerase 42
more...
Compound
ATP 1303
Dec 940
DNA 763
Clin 639
MDR 590
ADR 511
MTT 330
Adriamycin 328
sodium 288
Verapamil 269
Verapamil 268
water 257
PEG 207
oxygen 207
calcium 192
Cyclosporine 156
GSH 143
GSH 143
VP-16 132
Rhodamine 123 131
more...