Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.6.3.44 (
P-glycoprotein
)
13,344
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Adenocarcinoma
arising from a mediastinal cyst was detected by exercise technetium-99m hexakis-2-methoxyisobuty-lisonitrile (99m)Tc-MIBI scintigraphy in a 65-year-old woman with known coronary disease. This guided further investigations and resection of the tumor which stained positive for
P-glycoprotein
. Three years earlier, myocardial scintigraphy was negative, probably due to down-expression of
P-glycoprotein
because the cells were in the early stages of carcinogenesis. After completing malignant transformation, the high
P-glycoprotein
expression resulted in MIBI uptake on the second myocardial scintigraphy.
...
PMID:Malignant transformation of bronchogenic cyst revealed by 99mTc-MIBI-SPECT. 2271 31
