Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.6.3.1 (Mg2+-ATPase)
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Human Gene/Protein
ATP11A protein 14.4
TMEM150 13.4
CDC50A 13.2
ATP8A1 13.0
TMEM30A 12.9
ATP10B 12.8
ATP11A 12.8
ALDR1 12.8
skeletal muscle C-protein 12.8
myosin IA 12.7
ATP8B2 12.7
ATP11C 12.6
ATP10D 12.6
ATP8A2 12.5
RFT1 protein 12.4
myosin-ID 12.1
FRAG1 11.8
sodium/bile acid cotransporter 11.8
ATPase II 11.6
ATP10A 11.5
myosin IB 11.4
RGP1 11.4
LEM3 11.4
Arylamine N-acetyltransferase 1 11.4
ATP11B 11.4
ARV1 11.3
myosin I heavy chain 11.2
CDC50B 11.2
MLC-2A 11.2
MON2 11.1
aminophospholipid translocase 11.0
MYL12A 10.9
Rim protein 10.9
C21orf5 10.8
ATP9A 10.8
BIG3 10.7
ART5 10.7
VPS52 10.6
MYL6 10.6
MDR2 10.5
Ca2+-ATPase 10.5
NEO1 10.5
E-type ATPase 10.4
VPS54 10.4
APT1 10.2
VPS53 10.2
acidic calponin 10.0
ATP-hydrolysing 10.0
RME-8 9.9
ITPase 9.9
FAPP2 9.9
BEC-1 9.9
MDR3 9.7
NMHC-B 9.6
beta2-syntrophin 9.5
Caldesmon 9.5
RSK3 9.5
ABCB4 9.5
H+,K+-ATPase 9.4
adenylyl cyclase 2 9.4
SHD 9.4
myosin IC 9.3
PFIC 9.3
CHIF 9.2
Phospholipid scramblase 1 9.2
Mg(2+)-ATPase 9.1
myosin-like protein 9.0
MYL9 8.9
MYH10 8.8
ARL1 8.8
APT2 8.8
GAMT 8.7
axonemal dynein 8.7
oxysterol-binding protein 8.7
spectrin-like protein 8.7
ABCB11 8.7
ABCA4 8.7
5'-nucleotidase 8.6
ABCC7 8.5
GMF 8.5
more...
Disease
PFIC3 11.1
Guanidinoacetate methyltransferase deficiency 10.7
CDFI 10.4
STGD1 10.2
glycopenia 10.0
chemical hypersensitivity 9.7
PFIC2 9.6
PFIC1 9.6
DIOS 9.3
Benign recurrent intrahepatic cholestasis 9.2
hyperprolinemia 8.8
Shigella boydii 8.8
TD2 8.4
ANM 8.2
TD1 8.1
congenital hemolytic anemia 7.6
stomatocytosis 7.5
Dressler 7.5
avitaminosis 7.2
Tangier disease 6.9
codependency 6.8
cardiac overload 6.6
FFM 6.5
familial Alzheimer disease 6.4
acanthocytosis 6.4
Chimera 6.1
alcoholic cardiomyopathy 6.0
myotonia congenita 5.9
PGS 5.9
galactosemia 5.7
cholestasis 5.7
CSE 5.6
homocystinuria 5.5
Sandhoff disease 5.5
biliary colic 5.4
hepatic coma 5.3
hereditary spherocytosis 5.3
Shiga 5.2
hemiplegic migraine 5.2
blood disorder 5.2
malignant hyperthermia 5.2
Chronic GVHD 5.2
genetic hypertension 5.0
Goldblatt 5.0
EPS 5.0
idiopathic thrombocytopenic purpura 5.0
Shigella 4.9
NPS 4.9
EPS 4.9
mononeuropathy 4.8
kwashiorkor 4.7
EDC 4.6
LMS 4.5
Toxic epidermal necrolysis 4.4
Testis 4.4
Testis 4.4
cataplexy 4.3
Menkes 4.3
Angelman syndrome 4.3
Shigella dysenteriae 4.3
Staphylococcus aureus infection 4.3
hemolytic uremic syndrome 4.3
Cryptococcus neoformans 4.2
EL4 4.2
cholecystolithiasis 4.1
thiamine deficiency 4.1
steatorrhea 4.1
pseudotuberculosis 4.1
PIN 4.0
brain dysfunction 4.0
MMA 3.9
DM1 3.9
muscular dystrophy 3.9
porphyria 3.9
Neumann 3.8
pancreatic insufficiency 3.8
hyperhomocysteinemia 3.7
diabetic cardiomyopathy 3.7
lymphosarcoma 3.7
failure to thrive 3.6
more...
Symptom
inanition 6.6
polydipsia 3.3
cerebellar ataxia 2.6
hyperoxia 2.0
thinning 1.9
paresis 1.9
starvation 1.4
dystonia 1.4
hypothermia 1.3
diarrhea 1.2
exhaustion 0.7
anesthesia 0.2
tremor 0.2
discomfort -0.1
discomfort -0.2
fatigue -0.3
collapse -0.4
weakness -0.8
seizures -0.9
pain -3.6
Drug
Amdray 12.4
2,4,6-Trinitrophenol 11.4
Decane 9.7
Gamma-Aminobutyric acid 9.2
Phosphatidylserine 8.6
Levocabastine 8.4
FLP 7.3
DPE 7.3
Rhamnose 7.2
SrCl2 7.0
SrCl2 6.9
Trifluoperazine 6.6
RAL 6.4
Photofrin II 6.4
KCL 6.3
Bezafibrate 6.3
Gramicidin 6.2
Palmitoyl 6.2
Adenosine triphosphate 6.2
Ouabain 6.1
Auranofin 6.0
Caspofungin 5.9
Felodipine 5.9
Papaverine 5.5
ISP 5.5
Cibacron Blue 5.5
TAT 5.5
ABC 5.4
Neoral 5.4
Papain 5.3
NaI 5.1
NaI 5.1
NaI 5.1
NaI 5.1
CaCl2 5.1
CaCl2 5.1
Arsenic trioxide 5.1
CaCl2 5.0
Fraction 4.6
ALA 4.5
NVP 4.5
Galactose 4.4
CDP 4.2
RFP 4.1
Serum albumin 4.1
NADH 3.9
Mutagen 3.9
Amiloride 3.8
Triclosan 3.8
Amiloride 3.6
Gel 3.5
Theophylline 3.4
ADR 3.4
Captopril 3.2
Fragment 3.2
pyridoxal phosphate 3.1
Fluorescein 3.0
Asn 2.9
Taxol 2.7
Vitamin E 2.7
Kenyan 2.6
PCP 2.5
Glucagon 2.5
Fluorescein 2.5
ascorbate 2.5
DNase I 2.4
Adriamycin 2.2
Albumin 2.2
caffeine 2.0
TiO2 1.9
Indomethacin 1.8
ROS 1.7
NH3 1.6
ampicillin 1.4
lysine 1.4
vitamin E 1.3
Ethanol 1.1
Nephron 0.3
Cardiovasc -1.6
Enzyme
Mg2+-ATPase 14.4
EC 3.6.3.9 11.6
EC 1.12.2.1 10.8
UDP-N-acetylglucosamine 4-epimerase 10.7
p-nitrophenylphosphatase 9.5
MHCK 9.3
proton-translocating ATPase 9.3
ATP diphosphohydrolase 9.1
polysaccharide deacetylase 8.9
acyl-ACP synthetase 8.6
5'-nucleotidase 8.5
fatty acyl-CoA reductase 8.5
dolichol kinase 8.5
phosphatidylserine synthase 8.4
myosin ATPase 8.4
dynein ATPase 8.4
lysophosphatidylcholine acyltransferase 8.4
EC 3.6.1.1 8.3
EC 2.4.99.1 7.9
ATPase 7.9
ADPase 7.9
myosin light chain kinase 7.7
phosphatidylinositol synthase 7.7
phosphatidylethanolamine N-methyltransferase 7.6
calcium pump 7.4
H,K-ATPase 7.2
APS reductase 7.1
phosphatidate phosphatase 6.7
4-epimerase 6.7
apyrase 6.6
acylphosphatase 6.5
glucose-6-phosphatase 6.4
nucleoside hydrolase 6.3
citrate lyase 6.3
dissimilatory sulfite reductase 6.2
triphosphatase 6.1
penicillin acylase 6.1
carbamoylphosphate synthetase 6.1
galactokinase 6.1
UDP-glucose dehydrogenase 6.1
leucine aminopeptidase 6.0
sulfite reductase 6.0
sulfite reductase 6.0
ATP synthase 6.0
sulfite reductase 6.0
nucleotidase 6.0
succinic dehydrogenase 5.9
ACAT 5.9
nucleotide pyrophosphatase 5.9
beta-hydroxybutyrate dehydrogenase 5.8
rhodopsin kinase 5.8
adenylate kinase 5.8
lecithin:cholesterol acyltransferase 5.7
choline oxidase 5.7
P-glycoprotein 5.7
CPR 5.6
choline kinase 5.6
TAT 5.5
aldehyde reductase 5.4
aldehyde reductase 5.4
aldehyde reductase 5.3
sucrase 5.2
fumarate reductase 5.1
branching enzyme 5.1
diaphorase 5.0
adenylate cyclase 5.0
RNA ligase 5.0
succinate dehydrogenase 5.0
argininosuccinate synthetase 5.0
AMP deaminase 5.0
transhydrogenase 4.9
glycerol kinase 4.9
sphingosine kinase 4.8
CaMKII 4.7
phosphodiesterase 4.7
gamma-glutamyl transpeptidase 4.6
Pla 4.6
acid phosphatase 4.5
PDE 4.5
papain 4.5
more...
Compound
Hinesol 11.6
2-thioxo-1,3-thiazolidin-4-one 11.6
SC-13504 11.4
Plictran 11.1
Midecamycin 10.8
Midecamycin 10.8
Endothall 10.3
Rhodanine 10.0
Dicyclohexyl 9.8
Cetiedil 9.7
Erythrosin 9.2
C6H12O6 9.2
LDS-751 9.1
Methylmercuric chloride 8.7
Tetrahydrouridine 8.7
SDZ PSC 833 8.6
Phosphatidylserine 8.6
Picric acid 8.6
2,4-pentanedione 8.5
2,4-pentanedione 8.5
2,4-pentanedione 8.5
2,4-pentanedione 8.5
2,4-pentanedione 8.5
2,4-pentanedione 8.5
2,4-pentanedione 8.4
2,4-pentanedione 8.4
2,4-pentanedione 8.4
2,4-pentanedione 8.4
2,4-pentanedione 8.4
2,4-pentanedione 8.4
2,4-pentanedione 8.4
2,4-pentanedione 8.4
Isoproturon 8.3
2-butenoic acid 8.3
OCTA 8.2
Chlordecone 8.2
2-butenoic acid 8.1
Benzyl alcohol 7.9
UPP 7.8
GDP-L-fucose 7.8
HN2 7.7
2,4-pentanedione 7.7
Mg2+ 7.7
3-(dimethylamino)propyl 7.6
EEDQ 7.5
Phosphoserine 7.5
PIPES 7.3
PIPES 7.3
PIPES 7.3
Iodoacetamide 7.2
DDM 7.2
Ferricyanide 7.1
TDP 7.0
isopropylbenzene 6.9
Tetracaine 6.8
CTP 6.8
DTE 6.8
Sarin 6.8
DCC 6.8
ITP 6.7
HMM 6.7
TMPD 6.6
cis-vaccenic acid 6.6
Ethacrynic acid 6.6
Diamide 6.6
Trifluoperazine 6.6
PPi 6.6
MgCl2 6.5
Rhamnose 6.5
Aldrin 6.5
BBM 6.5
Endosulfan 6.5
Soman 6.4
Melittin 6.4
Aldrin 6.4
Digitonin 6.4
trimethyllysine 6.4
Ruthenium red 6.4
DMM 6.3
Ethacrynic acid 6.3
more...