Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.6.3.1 (
Mg2+-ATPase
)
1,484
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Rod
outer segments (ROSs) of vertebrate photoreceptor cells have been reported to contain several enzyme systems including a dark, Ca2+-stimulated ATPase, a rhodopsin kinase, a phosphodiesterase and a GTPase, all of which are light-stimulated. Recently, Thacher has found a light-stimulated
Mg2+-ATPase
in frog ROSs while our own laboratory has identified a dark, Ca2+-inhibited
Mg2+-ATPase
in bovine ROSs. Here we extend our observations on the
Mg2+-ATPase
and demonstrate that flash illumination following the dark ATPase process stimulated ATPase activity at a rate considerably faster than the dark process. In addition, we find that both the dark and light stimulated ATPase activities are markedly enhanced by cyclic GMP and inhibited by Ca2+.
...
PMID:Cyclic GMP stimulation of a light-activated ATPase in rod outer segments. 631 Apr 4
