Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.6.3.1 (Mg2+-ATPase)
 1,484 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

1. Indomethacin inhibits calcium-stimulated adenosine triphosphatase (Ca2+-ATPase), calcium, magnesium-stimulated adenosine triphosphatase (Ca2+,Mg2+-ATPase) and magnesium-stimulated adenosine triphosphatase (Mg2+-ATPase) activities in rat brain synaptic vesicles in vitro. 2. The Ca2+-ATPase activity is most strongly affected by this drug all of the activities of ATPases tested. 3. The decrease of Ca2+-ATPase activity by addition of indomethacin is due to a decrease of Vmax. 4. The Ki values for this drug for ATP and Ca2+ in Ca2+-ATPase were 1.13 mM and 0.68 mM, respectively.
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PMID:Effect of indomethacin on Ca2+-stimulated adenosine triphosphatase in the synaptic vesicles of rat brain in vitro. 621 40