Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.6.1.3 (ATPase)
 65,361 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hormonal control of osmoregulation in teleosts is not well understood. Role of cGH, oGH, PRL, T3 and insulin on gill Na+,K+-ATPase, Mg2+ and Ca2+ ATPases was studied in A. testudineus. Short term administration of cGH, PRL or T3 significantly increased Na+,K+-ATPase, Mg2+ and Ca2+ ATPases, while oGH influenced only Mg2+ ATPase, and insulin stimulated Na+,K+-ATPase. Long-term treatment with cGH and PRL also significantly increased Na+,K+-ATPase activity. GH had an additive with T3 on stimulating Na+,K+-ATPase activity. In vitro addition of cGH and oGH also had definite stimulatory effect on gill Na+,K+-ATPase except for 2ng oGH. Bromocryptine treatment caused a significant reduction on Na+,K+-ATPase activity. Both in vivo and in vitro treatments of cGH and PRL independently reversed the action of bromocryptine on Na+,K+-ATPase. Combined treatment of cGH+PRL was more prominent in stimulating Na+,K+-ATPase in bromocryptine treated fish. Present study reveals that GH, PRL and T3 have definite regulatory role on enzymes of osmoregulation in the teleost Anabas testudineus.
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PMID:Hormonal control on enzymes of osmoregulation in a teleost, Anabas testudineus (BLOCH): an in vivo and in vitro study. 1092 46