Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.6.1.3 (
ATPase
)
65,361
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Serotonin (10(-6)-10(-3) M) stimulates Na,K-
ATPase
in the rat brain cortex homogenate with a maximal effect at 10(-4) M.
Deseril
(10(-5) M), antagonist of serotonin receptors, removes the stimulating effect.
Deseril
has no influence on noradrenaline-induced
ATPase
activation; the alpha-adrenergic blocker phentolamine does not affect serotonin activation. The effects of the two transmitters are additive. It is assumed that the mediators interact with different membrane sites, serotonin activation being initiated via the serotonin receptors.
...
PMID:[Sites responsible for stimulation of brain Na,K-ATPase by serotonin]. 627 36
