Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.6.1.3 (ATPase)
 65,361 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

At birth, the diameter of muscle fibers in the M. masseter superficialis of rats has a narrow range. The diameters begin to increase rapidly from day 10 after birth, and on day 30 the diameters range between about 25 and 55 micrometers, and can be distinguished into 3 groups. SDH activity also increases in some fibers from day 10 and on day 15, 2 types of fibers can be distinguished on the basis of SDH activity, fibers of larger diameter having high activity. From day 30 to 60, 3 types of fibers can be distinguished on the basis of diameter and SDH activity. During this period, the diameter of fibers with the lowest SDH activity increases rapidly, the diameter of fibers with the highest SDH activity decrease transiently, and the diameter of fibers with intermediate SDH activity increases slightly. After day 60, the diameter of fibers with the highest SDH activity begins to increase again. Some fibers show high EDTA-insensitive ATPase activity for the first 15 days. This activity begins to decrease from day 15 after birth, and after day 25 it is no longer detectable in any fibers. No relation between SDH activity and EDTA-insensitive ATPase activity was found in serial sections of fibers. These results indicate that histochemical differences between muscle fibers of the M. masseter superficialis first appear during the late suckling period and develop gradually over a comparatively long period after weaning during use of the muscle for mastication.
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PMID:Postnatal development of masticatory organs in rats. I. consecutive changes in histochemical properties and diameter of muscle fibers of the M. masseter superficialis. 725 73

A comparison of the anatomy, fiber type profiles, and contractile properties of the wrist flexor muscles was undertaken in the cat. Isometric contractile characteristics were measured for each muscle. Three muscle fiber types, FG, FOG, and SO, were differentiated by staining cross sections of each muscle for ATPase, NADH diaphorase, SDH, and alpha-GPD activities. The wrist flexor muscles ranged from less than 1% to 49% SO fiber content; with two of the five heads of the flexor digitorium profundus (FDP) having 1% or less SO fibers (FDP1-1.07%, FDP5-0.81%) and the humeral head of the flexor carpi ulnaris muscle (FCUh) having the greatest content of SO fibers. The mean contraction time (CT) plus one-half relaxation time for an isometric twitch was correlated with the percentage of SO fibers and ranged from 40.5 to 111.8 ms. Except for the FCU (37ms), the CT was less than 25 ms for the wrist flexor muscles. The uniarticular wrist flexor muscles, the flexor carpi radialis (FCR), and the FCU had the highest percentage of SO fibers and were more fatigue-resistant that the multiarticular muscles. Considerable differences exist in muscle structure, fiber type proportions, and contractile properties between the FCR and FCU, which may be related to functional differences between the two sides of the wrist that may exist during the placement of the foot during locomotion.
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PMID:Morphological organization and contractile properties of the wrist flexor muscles in the cat. 725 81

The human endosalpingeal ciliated cells are not a homogeneous cell population. They can be distinguished into mitochondria prominent and normal cells. The morphological appearance of ciliated cells was studied in organ culture using different hormones and hormone combinations in the culture media. Histological (HE, semithin sections) and histochemical methods (PAS, Alcian Blue, SDH, LDH, ATPase, 5'-Nucleotidase, acid and alkaline Phosphatase) were applied. Those mitochondria prominent ciliated cells which are seen in the native endosalpinx can in vitro also be determined mainly under the influence of steroid hormones (hydrocortisone and progesterone). In hormone free incubation media the apices of ciliated cells are separated. This will happen in hormone containing media, too, but with delay, however. Some results are in agreement with the possible transformation from ciliated cells to secretory cells.
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PMID:[The histochemistry of human endosalpingeal ciliated cells (author's transl)]. 731 37

The effect of Xiaopiling Granules on muscular histochemistry of gastric precancerous changes in rats was observed quantitatively. The activity of SDH and M-ATPase as well as the content of muscular glycogen in model groups were found significantly lower than those of the normal groups (p < 0.01), and in this decrease Xiaopiling Granules had markedly played a preventive and therapeutic role.
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PMID:[Effect of xiaopiling granules on muscular histochemistry of gastric precancerous changes in rats]. 762 13

Fiber types distribution in the digastric muscle of tufted capuchin monkey was studied by means of NADH-TR, myosin-ATPase, after alkaline and acid preincubations and SDH histochemical reactions. Three different types of fibers were found presenting an equal distribution. The percentage and types of fibers were as follow: 18.2% SO (Slow Oxidative), 38.4% FOG (Fast Oxidative Glycolytic) and 43.4% FG (Fast Glycolytic). FG fibers revealed the largest area. The relatively high concentration of fast twitch (81.2%) seems to indicate this muscle is involved with the acceleration and fast speed of jaw movements. Aerobic metabolism represented by SO + FOG fibers (56.6%) suggests that this muscle possesses an additional role than that related to the lowering of the jaw.
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PMID:Fiber types distribution in the digastric muscle of tufted capuchin monkey (Cebus apella). 786 96

Neuromuscular activity was eliminated in the tibialis anterior muscle of adult cats for 6 months by spinal isolation (SI), i.e., complete spinal cord transections at T-12-13 and at L-7-S-1, plus bilateral dorsal rhizotomy between the two transection sites. One motor unit from each muscle was isolated using ventral root teasing procedures and physiologically tested. The fibers belonging to each motor unit were visualized in PAS-stained sections by the loss of glycogen following prolonged repetitive stimulation. Qualitatively, the normal enzymatic interrelationships among fibers identified by myosin heavy chain composition were unchanged by SI. Generally, each motor unit from SI cats were of a single myosin immunohistochemical type. The same physiological motor unit types that typify control muscles were found in SI cats. In SI compared to control cats, there was approximately a 10% increase in the number of muscle fibers expressing fast myosin. Mean fiber activity levels of ATPase and SDH for a given fiber type (based on MHC antibody reactions) decreased by approximately 10% and 25%, whereas GPD activity increased approximately 35%. It is concluded that differential levels or patterns of activity are not essential to maintain the range of histochemical and physiological motor unit types found in the tibialis anterior of normal adult cats.
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PMID:Level of independence of motor unit properties from neuromuscular activity. 793 55

We analyzed the masticatory muscles (masseter, temporal, medial pterygoid and lateral pterygoid muscles) of Bovidae and Cervidae (Artiodactyla) for the histochemical characteristics of their fiber types. Analysis of muscle fiber types in the present study was based on the staining reaction for SDH, Sudan black B, alpha-GPDH, and myosin-ATPase after alkaline preincubations. Histochemical properties were found to contribute to masticatory function, including a slow-twitch fatigue resistant activity derived from the high percentage of red fibers, in spite of the differences in the distributions of fiber types in three portions (superficial, medial and profound portions) of each masticatory muscle. These results indicate a correlation between the histochemical profiles of individual masticatory muscles in these species and their functions during jaw movements.
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PMID:Differentiation of histochemical properties of masticatory muscles in Bovidae and Cervidae (Artiodactyla). 804 63

Parallel oxygraphic measurements of respiratory control index (RCI) and spectroscopic measurements of the activity of two mitochondrial enzymes from rat muscle, mtATPase and succinate dehydrogenase were performed. In Trichinella spiralis infection, in comparison with Trichinella pseudospiralis infection, a delayed stimulation of mtATPase in 3rd week p.i. was observed and the degree of stimulation was weaker. A second peak of mtATPase stimulation appeared at the beginning of the encystation phase. The two-phase phenomenon was accompanied by a sharp decrease of RCI to 39% of normal values and almost 2-fold increase in the ratio of Mg(2+)-stimulated to Mg(2+)-unstimulated mtATPase. By the end of investigations (7th week) the level of SDH normalized, but mtATPase was still elevated. The results, as in the case of T. pseudospiralis infection, support the testing of mtATPase activity to follow bioenergetic changes in tissue parasite infections. In comparison with oxygraphic measurements ATPase testing needs a much smaller amount of biological material and ATP.
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PMID:Dynamics of rat muscle mitochondria uncoupling in trichinellosis. 822 61

Four fiber types have been characterized in different pigeon skeletal muscles according to their innervation pattern (nerve ending structure and innervation distribution) and histochemical properties (SDH and m-ATPase activities). All fast fibers, types IIA and IIB, present aggregated distribution of their nerve endings with "en plaque" structures and very low innervation frequencies. The two kinds of slow fibers recognized are multiple innervated and present higher innervation frequencies. However, type I fibers have nerve terminals in small knobs with uniform localization, whereas type III fibers present "en grappe" nerve endings, which tend to be randomly distributed. Fiber type composition of skeletal muscles has been found closely related to their biomechanical function. Fast fibers are predominant in muscles with an active role in locomotive movements, whereas slow fibers are mainly or exclusively located in postural muscles.
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PMID:Innervation distribution pattern, nerve ending structure, and fiber types in pigeon skeletal muscle. 823 69

Two strains of Chlamydia psittaci (one isolated from aborted goat foetus and the other from brain of a buffalo calf that had died of meningoencephalitis) were injected intracisternally into six goats to produce experimental mastitis. Cryostat sections of 7-8 microns thickness, obtained from udder, teat, liver and kidney of infected and control animals were incubated for histoenzymic demonstration of alkaline-(AKPase), acid-(ACPase) and adenosine-tri-(ATPase) phosphatases; lactate-(LDH) and succinate-(SDH) dehydrogenases and for reduced nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-D). Results demonstrated that AKPase and NADPH-D declined while ACPase accumulated in acinar cells of udder while both NADPH-D and ACPase decreased in teat sinus epithelium. Hepatic canaliculi in perilobular areas of liver lobules registered complete absence of AKPase and ATPase. Hepatocytes and renal tubules accumulated LDH, SDH and NADPH-D. The interstitial connective tissue of udder and kidney presented higher levels of AKPase. Comparison of results with biochemical alterations in the level of these enzymes revealed striking discrepancies which seem to arise because of failure of biochemical procedures to discriminate between functional cells of tissue and inflammatory cells. The functional significance of histoenzymic alterations has been discussed.
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PMID:Studies on experimental chlamydial mastitis in goat histoenzymology. 828 44


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