Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.6.1.3 (
ATPase
)
65,361
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Hypokalemia potentiated the arryhthmogenic effects of digoxin and promoted inhibition of cardiac Na+,K+-
ATPase
.
Acute hypokalemia
did not modify digoxin-induced inotropy and therefore altered the quantitative relationship between inhibition of Na+,K+-
ATPase
and positive inotropy. Chronic hypokalemia impaired the positive inotropic response to digoxin and to isoproterenol in the absence of an electron microscopically detectable cardiomyopathy.
...
PMID:Effects of hypokalemia on the cardiotropic actions of digoxin in dogs. Correlation with inhibition of cardiac Na+,K+-adenosine triphosphatase. 644 96
