Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.6.1.25 (triphosphatase)
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Human Gene/Protein
EH domain containing 2 14.3
Src homology 3 domain-containing guanine nucleotide exchange factor 13.3
YSA1H 13.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 13.3
histidine triad nucleotide binding protein 3 13.3
RNA (guanine-7-) methyltransferase 13.3
CYTH3 13.3
WDR75 13.3
EFA6R 12.8
BORG4 12.8
SH3 domain-binding protein 4 12.8
PARIS-1 protein 12.8
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 12.8
NUBP1 12.8
HCA67 12.8
Borg5 12.8
GPR137B 12.3
C6orf203 12.3
DIPP2 12.3
thiamine triphosphatase 12.3
EH domain-binding protein 1 12.2
ARF1 GAP 12.0
Ras homolog gene family, member C 12.0
CPNE6 12.0
GTase 11.9
TBC1D14 11.8
POLR2C 11.8
PIR1 11.8
FHOD2 11.8
RHOBTB1 11.8
ADP-ribosylation factor-related protein 1 11.8
hSPT5 11.8
CCDC85A 11.8
RGS-PX1 11.8
CLEC14A 11.6
NUBP2 11.5
Intersectin 2 11.5
ADP-ribosylation factor-like 2 11.5
ELMOD1 11.5
CD39L2 11.5
Rho-related BTB domain-containing protein 3 11.5
syntaxin 10 11.3
LRRC7 11.3
CD39L1 11.2
RTKN2 11.2
CFD1 11.2
Cortactin-binding protein 2 11.2
CD39L3 11.0
DABP 11.0
RRAGA 10.9
growth-regulating protein 10.9
PLEKHM2 10.9
RAB35 10.9
Use1 10.9
ARL8 10.9
RAB32 10.9
TBC1D10A 10.9
sec23 10.8
NTPDase8 10.8
GA protein 10.8
D-AKAP2 10.6
SLAT 10.6
MTG1 10.6
ArhGAP15 10.6
CRAG 10.6
hMet 10.6
Ral guanine nucleotide exchange factor 10.5
SH3BP1 10.5
budding uninhibited by benzimidazoles 1 10.5
RIC3 10.5
MICAL-L2 10.5
Mitotic centromere-associated kinesin 10.4
ectonucleoside triphosphate diphosphohydrolase 5 10.4
MyoGEF 10.4
C12orf65 10.4
protein tyrosine phosphatase receptor type D 10.4
paracingulin 10.3
oxysterol-binding protein-related protein 10.3
E-type ATPase 10.3
RGS12 10.3
more...
Disease
Morris Hepatoma 9.6
XRN 9.4
Rinderpest 9.0
cHL 9.0
GCS1 8.8
Carpenter syndrome 8.6
Neovascular age-related macular degeneration 8.3
audiogenic epilepsy 8.3
HPC1 8.3
cardiofaciocutaneous syndrome 8.0
NS3 7.9
OPA1 7.8
HOPS 7.6
Shope fibroma 7.1
Costello syndrome 7.1
RGS 7.1
RAT 7.1
audiogenic seizure 7.0
Aeromonas hydrophila infection 7.0
CGD 6.5
AD1 6.5
Degos 6.3
vaccinia 6.2
megakaryocytic leukemia 6.2
BEN 6.1
chondrolysis 6.0
spondyloepiphyseal dysplasia 6.0
PBD 6.0
idiopathic thrombocytopenic purpura 6.0
West Nile Virus 5.9
Liver regeneration 5.8
Fallopian tube 5.8
Sutton 5.8
thyroid adenoma 5.7
Hereditary spastic paraplegia 5.7
Kartagener's syndrome 5.7
Sander 5.7
Lesch-Nyhan syndrome 5.6
Recklinghausen 5.6
Pleomorphic adenoma 5.6
dumping syndrome 5.6
MEN 2B 5.5
hairy leukoplakia 5.5
benign nevi 5.5
HPC 5.5
myeloblastosis 5.4
TTP 5.4
amebic colitis 5.4
Joubert syndrome 5.4
Classical swine fever 5.3
optic atrophy 5.2
Zinc deficiency 5.2
PPP 5.2
Ductal 5.1
African swine fever 5.1
Japanese encephalitis 5.0
neurofibromatosis type 1 4.9
inflammatory breast cancer 4.9
cutis laxa 4.9
Crouzon syndrome 4.9
dengue 4.9
TTP 4.9
Lennox-Gastaut syndrome 4.8
Apert syndrome 4.8
BCH 4.8
COL2A1 4.8
molluscum contagiosum 4.8
lipid disorder 4.7
Small cell carcinoma 4.7
Lennox-Gastaut syndrome 4.6
NS2 4.6
magnesium deficiency 4.6
Hypertrophic 4.6
Hermansky-Pudlak syndrome 4.6
HCI 4.6
viral diarrhea 4.5
hepatitis C 4.5
Hypertrophic cardiomyopathy 4.5
self-injurious behavior 4.4
Cholangiocarcinoma 4.4
more...
Symptom
male subfertility 6.3
rundown 5.4
fasciculation 4.0
menopausal symptoms 3.7
twitching 3.3
masculinization 3.0
starvation 2.7
cachexia 1.9
hypotonia 1.8
flushing 1.7
spasticity 1.7
collapse 1.5
spasm 1.5
dystonia 1.3
splenomegaly 1.1
anorexia 0.6
acidity 0.5
ataxia 0.4
seizures 0.4
hypothermia 0.3
angina -0.0
fatigue -0.3
weakness -0.9
anesthesia -1.4
pain -2.6
Drug
Sinefungin 8.6
Coal tar 8.4
Domin 7.9
Mizoribine 7.7
Hydergine 7.5
Carbidopa 7.0
Malachite Green 6.9
Spiegel 6.5
RAL 6.4
Pyridoxal 6.3
Alanine 6.1
Methylprednisolone 5.5
Papaverine 5.5
Sinemet 5.3
Ouabain 5.1
Pravastatin 4.7
Adenosine triphosphate 4.5
DFP 4.5
Parkin 4.5
Parkin 4.5
Isoniazid 4.4
CDP 4.2
Vitamin B 4.1
ZnCl2 4.0
ZnCl2 4.0
Lovastatin 4.0
BLM 3.9
Glycyrrhiza 3.9
IFN-beta 3.8
Amiloride 3.8
Acacia 3.7
Simvastatin 3.7
Amiloride 3.5
-deoxyadenosine 3.3
NAG 3.3
NADH 3.2
G418 3.2
Herceptin 3.2
Fragment 3.2
Asn 3.2
TAT 3.1
ETS 3.0
ICI 3.0
Ringer's solution 2.9
lysine 2.8
CaCl2 2.7
CaCl2 2.7
Taxol 2.7
CaCl2 2.7
Gel 2.5
p75 2.4
Spectrum 2.4
Ethanol 2.1
FAD 1.9
Histamine 1.9
Bifidobacterium 1.8
MAP 1.4
Spectrum 1.4
ABC 1.2
citric acid 1.1
ZnO 0.6
vitamin E 0.2
Nephron 0.2
caffeine -0.1
Asthma -0.3
IFN-gamma -0.5
IL-2 -0.5
CSF -0.6
Dermatol -0.7
Enzyme
triphosphatase 14.3
EC 3.6.1.16 14.3
adenylylsulfate-ammonia adenylyltransferase 14.3
EC 3.6.1.28 13.3
EC 3.6.2.1 13.3
EC 3.6.1.29 13.3
nucleoside triphosphate phosphohydrolase 12.3
EC 3.6.1.17 11.6
NS protease 11.3
Protein 2 10.9
EC 2.7.4.15 10.9
dGTPase 10.2
Dol-P phosphatase 9.9
Ap4A hydrolase 9.8
dTTPase 9.6
i-AAA protease 9.5
GDPase 9.5
dCTP deaminase 9.2
nicotinamide adenine dinucleotide glycohydrolase 9.0
dCTP deaminase 9.0
ATPase 8.9
m-AAA protease 8.8
ADPase 8.7
trimetaphosphatase 8.6
beta-glycerophosphatase 8.6
poly(A)-specific ribonuclease 8.5
dolichol kinase 8.4
DIPP 8.4
EC 3.6.1.1 8.2
poly(A)-specific ribonuclease 8.0
nucleoside diphosphokinase 8.0
exopolyphosphatase 7.9
gluconate dehydrogenase 7.9
thiamine pyrophosphokinase 7.7
elongation factor (EF) 7.7
glycerol-3-phosphate oxidase 7.7
nucleotidase 7.5
CTD kinase 7.2
5'-nucleotidase 7.2
endonuclease V 7.2
ATP diphosphohydrolase 7.1
poly(A) polymerase 7.0
dCMP deaminase 6.9
glucose-6-phosphatase 6.7
p-nitrophenylphosphatase 6.6
succinic dehydrogenase 6.6
apyrase 6.6
exonuclease I 6.5
proton-translocating ATPase 6.5
acylphosphatase 6.5
histidase 6.5
glycine decarboxylase 6.2
Mg2+-ATPase 6.1
cGMP phosphodiesterase 6.0
callose synthase 6.0
inositol phosphatase 6.0
nitrile hydratase 5.9
deoxyribonuclease 5.8
sphingosine kinase 5.8
deoxyribonuclease 5.8
carboxypeptidase E 5.7
3'-exonuclease 5.7
dUTPase 5.7
NAD glycohydrolase 5.6
venom phosphodiesterase 5.5
adenylate kinase 5.4
3-hydroxy-3-methylglutaryl coenzyme A reductase 5.4
calcium pump 5.4
CNPase 5.3
succinate dehydrogenase 5.3
p80 5.2
myosin ATPase 5.2
pyruvate kinase 5.2
acid phosphatase 5.2
transcriptase 5.0
polynucleotide kinase 5.0
3-hydroxyacyl-CoA dehydrogenase 4.9
phosphatidylinositol 4-kinase 4.9
3-hydroxyacyl-CoA dehydrogenase 4.9
cholesterol oxidase 4.9
more...
Compound
3-hydroxybenzonitrile 12.3
Chlormerodrin 12.0
GppppG 11.5
Deoxyuridine 11.2
Kirromycin 10.8
Purine riboside 10.5
Thiamine triphosphate 10.0
Thiamine triphosphate 10.0
benzyl thiocyanate 9.6
Methapyrilene 9.0
dIMP 9.0
Pinitol 8.6
Thiostrepton 8.5
dITP 8.4
GAP 8.4
Azocoll 8.2
Adenosine 8.2
Adenine arabinoside 8.1
XTP 8.0
dGTP 8.0
Etorphine 7.9
ITP 7.8
dCDP 7.7
Sodium deoxycholate 7.7
Resazurin 7.5
dUDP 7.5
Triphosphate 7.4
dADP 7.4
Pantoprazole 7.2
dATP 7.2
CTP 7.2
Vinyl chloride 7.1
Dolichol 7.1
TTP 7.1
XMP 7.0
UTP 7.0
Fusidic acid 6.9
3'-AMP 6.9
Monocrotaline 6.8
Guo 6.8
7-methylguanosine 6.7
GTP 6.7
P2A 6.7
PPi 6.7
Thiamine 6.7
ribose-5-phosphate 6.7
GMP 6.6
dUMP 6.6
tetraphosphate 6.5
Ara-A 6.4
Rottlerin 6.4
TDP 6.4
dCTP 6.4
Cyproterone acetate 6.4
Rottlerin 6.3
Rottlerin 6.3
Pyridoxal 6.3
Beryllium 6.3
Inosine 6.3
dGMP 6.3
GDP 6.3
Deoxycholic acid 6.2
1,2,3,4-tetrahydronaphthalene 6.2
Cyanogen bromide 6.2
PGA2 6.1
methylguanosine 6.1
Alanine 6.1
Cordycepin 6.1
Cordycepin 6.1
Cordycepin 6.1
IDP 6.1
NEM 6.0
PBD 6.0
Fluvoxamine 5.9
Mg2+ 5.9
Guo 5.9
Rhodopsin 5.9
quinuclidine 5.9
quinuclidine 5.9
Triton WR-1339 5.8
more...