Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.6.1.25 (triphosphatase)
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Human Gene/Protein
EH domain containing 2 14.3
Src homology 3 domain-containing guanine nucleotide exchange factor 13.3
CYTH3 13.3
RNA (guanine-7-) methyltransferase 13.3
WDR75 13.3
YSA1H 13.3
histidine triad nucleotide binding protein 3 13.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 13.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 12.8
EFA6R 12.8
PARIS-1 protein 12.8
SH3 domain-binding protein 4 12.8
Borg5 12.8
BORG4 12.8
HCA67 12.8
NUBP1 12.8
GPR137B 12.3
C6orf203 12.3
DIPP2 12.3
thiamine triphosphatase 12.3
EH domain-binding protein 1 12.2
ARF1 GAP 12.0
Ras homolog gene family, member C 12.0
CPNE6 12.0
GTase 11.9
POLR2C 11.8
FHOD2 11.8
RGS-PX1 11.8
ADP-ribosylation factor-related protein 1 11.8
hSPT5 11.8
PIR1 11.8
RHOBTB1 11.8
CCDC85A 11.8
TBC1D14 11.8
CLEC14A 11.6
NUBP2 11.5
Intersectin 2 11.5
Rho-related BTB domain-containing protein 3 11.5
ADP-ribosylation factor-like 2 11.5
ELMOD1 11.5
CD39L2 11.5
LRRC7 11.3
syntaxin 10 11.3
CD39L1 11.2
CFD1 11.2
RTKN2 11.2
Cortactin-binding protein 2 11.2
DABP 11.0
CD39L3 11.0
growth-regulating protein 10.9
PLEKHM2 10.9
Use1 10.9
RRAGA 10.9
ARL8 10.9
TBC1D10A 10.9
RAB32 10.9
RAB35 10.9
sec23 10.8
NTPDase8 10.8
GA protein 10.8
ArhGAP15 10.6
CRAG 10.6
MTG1 10.6
SLAT 10.6
D-AKAP2 10.6
hMet 10.6
SH3BP1 10.5
budding uninhibited by benzimidazoles 1 10.5
MICAL-L2 10.5
RIC3 10.5
Ral guanine nucleotide exchange factor 10.5
Mitotic centromere-associated kinesin 10.4
C12orf65 10.4
ectonucleoside triphosphate diphosphohydrolase 5 10.4
MyoGEF 10.4
protein tyrosine phosphatase receptor type D 10.4
E-type ATPase 10.3
paracingulin 10.3
oxysterol-binding protein-related protein 10.3
RGS12 10.3
EHBP1 10.3
RHOJ 10.3
CES5 10.3
SGEF 10.3
EIF4A2 10.2
AFG3 10.2
regulator of G protein signaling protein 10.2
LRG-47 10.2
Seh1 10.1
Cdc42 GTPase-activating protein 10.1
WDR41 10.1
RAB13 10.1
STX6 10.1
PPP2CB 10.0
DFNA1 10.0
TRIP-1 10.0
DHX29 10.0
RPGR protein 10.0
Par1b 10.0
LMTK3 10.0
KCTD10 10.0
semaphorin 3E 10.0
NTPase 9.9
YAP65 9.9
phosducin-like 9.9
ACBD3 9.9
TLN 9.8
p126 9.8
guanine nucleotide exchange factor for Rap1 9.8
N-ras protein 9.8
ITPase 9.8
ITSN 9.8
RAB38 9.8
mRNA decapping enzyme 9.8
GCC185 9.8
brefeldin A-inhibited 9.8
CHN1 9.8
CTL1 9.7
ARAP3 9.7
MYO9B 9.7
MTH1 9.7
TANGO1 9.7
RAB39B 9.6
ARAP1 9.6
IRG1 9.6
PKN2 9.6
RagD 9.6
RagC 9.6
sedlin 9.5
SLC38A9 9.5
Vti1a 9.5
FBLN5 9.5
polo-like kinase 2 9.5
septin 4 9.5
ARHGAP18 9.4
adenylate cyclase 3 9.4
ecto-ATPase 9.4
RINT-1 9.4
RAB23 9.4
RGS18 9.4
p101 9.4
ATG101 9.3
adenylate kinase 2 9.3
TAGAP 9.3
ARHGDIB 9.3
Nanog homeobox 9.3
ARHGAP21 9.3
p21-activated kinase 3 9.3
WNK2 9.3
dynamin 1 9.3
GC kinase 9.3
Plexin-B1 9.2
tescalcin 9.2
SEPT4 9.2
UDPase 9.2
OPA1 protein 9.2
Rnd1 9.2
MIG-2 9.2
Succinic dehydrogenase 9.2
p120GAP 9.2
Tre-2 9.2
RGS6 9.2
Grp1 9.2
CDC42Hs 9.2
NSP2 9.2
Cep164 9.1
E2K 9.1
syntaphilin 9.1
carbonate dehydratase 9.1
regulator of chromosome condensation 1 9.1
YME1L 9.1
BCAR3 9.1
Rab-interacting lysosomal protein 9.1
ROMO1 9.1
FMNL1 9.1
PLC-I 9.1
putative ATPase 9.1
RHAU 9.1
HEF1 9.0
JLP 9.0
WRP 9.0
RNA helicase 9.0
HD-6 9.0
PAAF 9.0
DOCK2 9.0
STX16 9.0
Ras-like 9.0
SAR1B 8.9
neural retina leucine zipper 8.9
NuMA protein 8.9
ZBRK1 8.9
putative RNA helicase 8.9
lamellipodin 8.9
Cardiac ankyrin repeat protein 8.9
Protein interacting with C kinase 1 8.9
TTBK2 8.9
basal cell adhesion molecule 8.9
FMNL2 8.9
PKN1 8.9
PKN 8.9
RPS7 8.9
CFL2 8.9
Tuba 8.9
Rnd3 8.9
Interferon regulatory factor 1 8.9
SH3TC2 8.9
SmgGDS 8.9
GCS1 8.8
ARL13B 8.8
DHX36 8.8
ADP-ribosylation factor 1 8.8
BCAM 8.8
p21-activated kinase 2 8.8
tuberous sclerosis 1 8.8
FHIT protein 8.7
SESN1 8.7
regulator of microtubule dynamics 8.7
VPS1 8.7
SPT5 8.7
Endoribonuclease 8.7
CCM1 8.7
RagA 8.7
protein kinase D1 8.7
Helicase 8.6
RCC1 8.6
mitochondrial Rho 8.6
SLA2 8.6
GIT2 8.5
syntaxin 17 8.5
SPG3A 8.5
integrin alpha subunit 8.5
TAL-1 8.5
Plexin-A1 8.5
RGS11 8.5
AFG3L2 8.5
DLG2 8.5
helicase II 8.5
GAP 8.5
MEG2 8.5
IRGM 8.5
neurofibromin 8.5
BNIP-2 8.4
p115 8.4
cullin 1 8.4
FKBP38 8.4
EHD2 8.4
RAP1A 8.4
DIPP 8.4
DBY 8.4
apolipoprotein B mRNA editing enzyme 8.4
SLIT3 8.4
Krev-1 8.4
transcription factor E3 8.4
Chibby 8.3
NIFL 8.3
adenosine triphosphatase 8.3
ribosomal protein S2 8.3
Rabaptin-5 8.3
amphiphysin II 8.3
Ras-related protein 8.3
GBP1 8.3
p84 8.3
hematopoietic cell-specific 8.3
soluble NSF attachment protein 8.3
INF2 8.3
tuberous sclerosis 2 8.3
Microtubule-associated protein 2 8.3
fibulin-4 8.3
DNM2 8.3
ADP-ribosylation factor 6 8.2
RGS10 8.2
RGS14 8.2
DNAJB6 8.2
actin-capping protein 8.2
LRG 8.2
ZW10 8.2
fragile histidine triad 8.2
RhoGEF 8.2
oligodendrocyte myelin glycoprotein 8.2
SWAP-70 8.2
Afadin 8.2
p83 8.2
Ras homolog enriched in brain 8.2
espin 8.2
NORE1A 8.2
ANLN 8.2
alternative splice product 8.1
Rabex-5 8.1
p230 8.1
RhoG 8.1
guanine nucleotide exchange factor 8.1
Rhotekin 8.1
G alpha q 8.1
E1B19K 8.1
SNM1 8.1
elongation factor G 8.1
cullin 3 8.1
RNASEL 8.1
BAI1 8.1
SP-10 8.1
ACAP 8.0
EF1A 8.0
Citron 8.0
WAVE2 8.0
transducin alpha 8.0
rac1 8.0
NELF 8.0
OPA1 8.0
EEF1A1 8.0
NTP 8.0
NCK 8.0
alternatively spliced product 7.9
TBC1D4 7.9
member 9 7.9
DENN 7.9
PCM1 7.9
RAB5 7.9
CLC-5 7.9
CHAD 7.9
RhoC 7.9
Ras association 7.9
GGA3 7.9
WW domain-containing 7.9
PDE2A 7.9
9 kDa protein 7.9
YPT1 7.9
ADPase 7.9
PDZ-RhoGEF 7.8
MFF 7.8
RGS9 7.8
plexin 7.8
HCE 7.8
regulator of G protein signaling 7.8
BCR-ABL fusion protein 7.8
calcineurin B-like protein 7.8
helicase 7.8
PAK3 7.8
CDK-activating kinase 7.8
chromosome 9 open reading frame 72 7.8
Rheb 7.8
TRAF4 7.7
RPGR 7.7
GIPC 7.7
p67-phox 7.7
NCF 7.7
alpha polypeptide 7.7
mixed lineage kinase 3 7.7
mu2 7.7
gene 4 7.7
GTPase-activating protein 7.7
RAF-1 7.7
CRBN 7.7
HOPS 7.7
ATP diphosphohydrolase 7.7
dynamin 7.7
ATAD2 7.6
RGS 7.6
melanophilin 7.6
thiamine pyrophosphokinase 7.6
nucleotide-binding oligomerization domain 2 7.6
p21-activated protein kinase 7.6
Eps8 7.6
Galphaz 7.6
myosin phosphatase target subunit 1 7.6
VAMP3 7.6
CEL 7.5
TIP47 7.5
cation dependent 7.5
guanine nucleotide-binding protein 7.5
K79 7.5
RAB7 7.5
CapZ 7.5
cytotoxic T-lymphocyte-associated antigen 4 7.5
tubby 7.5
sphingosine-1-phosphate receptor 1 7.5
Rho 7.5
VHR 7.5
rabphilin 7.5
GDI 7.5
SLIT2 7.5
RhoGAP 7.5
GAIP 7.5
SAMHD1 7.5
110 kDa protein 7.5
alpha II 7.5
elongation factor Tu 7.4
giantin 7.4
dolichol kinase 7.4
iron regulatory protein 1 7.4
GEF-H1 7.4
regucalcin 7.4
SKIP 7.4
NEDD9 7.4
CTD kinase 7.4
HPC1 7.4
alpha-adducin 7.4
ENT2 7.4
phosphatidylinositol 4-phosphate 5-kinase 7.4
CT10 7.4
cyclin C 7.4
ERAS 7.4
EFA6 7.3
NDP kinase 7.3
ROCK1 7.3
ung 7.3
MGST1 7.3
C3G 7.3
SEPT9 7.3
PPX 7.3
APPL1 7.3
p40phox 7.3
p67phox 7.3
pyrophosphatase 7.3
Fis1 7.3
RhoE 7.2
5'-nucleotidase 7.2
GMP 7.2
RGS4 7.2
EB3 7.2
DOCK180 7.2
neuropilin 1 7.2
GTPase activating protein 7.2
RGS7 7.2
ERCC4 7.2
IRSp53 7.2
CTP 7.2
trypsin-like serine protease 7.2
DRP1 7.2
TC4 7.2
UBC13 7.2
cyclin T 7.2
Rab7 7.2
TFII-I 7.1
platelet collagen receptor 7.1
hexokinase 1 7.1
B1R 7.1
RAB 7.1
H-RAS 7.1
p130cas 7.1
AAAS 7.1
HD-5 7.1
ephrin-A1 7.1
ROCK2 7.1
NDP52 7.1
TGase 7.1
AIF4 7.1
small G protein 7.1
CDC42 7.1
pleckstrin 7.1
PI3Kgamma 7.1
leucine-rich repeat kinase 2 7.1
Rab27a 7.1
ROBO1 7.1
decapping enzyme 7.1
TREX1 7.0
G13 7.0
Kindlin-2 7.0
inorganic pyrophosphatase 7.0
gamma-glutamyltranspeptidase 7.0
nuclear envelope protein 7.0
RasGAP 7.0
RhoA 7.0
signal recognition particle 7.0
GTP binding protein 7.0
small GTP-binding protein 7.0
VH1 7.0
NSP5 7.0
Rho-associated protein kinase 1 7.0
ATP-dependent RNA helicase 7.0
mitochondrial glycerol-3-phosphate dehydrogenase 6.9
isocitric dehydrogenase 6.9
Leucine-rich repeat kinase 2 6.9
AF6 6.9
XMP 6.9
RNA helicase A 6.9
p47 6.9
growth factor receptor-bound protein 2 6.9
chemokine receptor 3 6.9
LIMK 6.9
NS5 6.9
SSTR3 6.9
dCMP deaminase 6.9
6PGD 6.9
PARK6 6.8
ATPase mRNA 6.8
septin 6.8
semaphorin 6.8
SRP54 6.8
CHIP28 6.8
p190RhoGAP 6.8
AS160 6.8
DDX3X 6.8
histone-binding 6.8
GTP 6.8
DNA-dependent DNA polymerase 6.8
Crk-associated substrate 6.8
citron 6.8
ARF1 6.8
amphiphysin 6.7
apyrase 6.7
Bik 6.7
Gsalpha 6.7
IQGAP1 6.7
Acid phosphatase 6.7
FRA3B 6.7
CD39 6.7
glucose-6-phosphatase 6.7
ICAM-2 6.7
DNA helicase 6.7
MYH 6.7
Phosphoinositide 3-kinase 6.6
putative oncogene 6.6
Glucose-6-phosphatase 6.6
DNA primase 6.6
PAC-1 6.6
syntaxin-4 6.6
glutathione S-transferase fusion protein 6.6
dual-specificity phosphatase 6.6
single-stranded DNA-binding protein 6.6
p22phox 6.6
p47phox 6.6
acylphosphatase 6.6
PAR-6 6.6
Amphiphysin 6.6
Rhodopsin 6.5
ITGA5 6.5
ADH1 6.5
sex determining region Y 6.5
regulator of G-protein signaling 6.5
BUB1 6.5
BEN 6.5
p26 6.5
vacuolar protein sorting 6.5
dynamin 2 6.5
XMAP215 6.5
CRA 6.5
CDM 6.5
ras 6.5
EPAC 6.5
guanine nucleotide binding protein 6.5
IMPDH 6.5
GPD 6.5
AD1 6.5
mitogen-activated protein kinase kinase 1 6.5
RF1 6.5
WNT1 6.4
TGN38 6.4
AC5 6.4
PH domain 6.4
H-ras 6.4
GM130 6.4
NF1 6.4
HSP70-1 6.4
transcription elongation factor 6.4
PRLR 6.4
inositol phosphatase 6.4
rapsyn 6.4
CSN5 6.4
methyltransferase 6.4
p67 6.4
HK1 6.4
synaptojanin 6.4
Rab GTPase 6.4
RAC1 6.3
exonuclease I 6.3
mitochondrial ATPase 6.3
Cdc45 6.3
cell cycle regulatory protein 6.3
TF1 6.3
zinc finger motif 6.3
WAVE 6.3
actin-related protein 6.3
Adenylyl cyclase 6.3
LAMP2 6.3
GDP dissociation inhibitor 6.2
GDP 6.2
Nucleophosmin 6.2
dUTPase 6.2
RhoB 6.2
LEDGF 6.2
DLK1 6.2
phosphatidylinositol 4-kinase 6.2
RAL 6.2
mitogen-activated protein kinase kinase kinase 6.2
adenosinetriphosphatase 6.2
p47-phox 6.2
Receptor tyrosine kinase 6.2
PKC zeta 6.1
p110 6.1
Wnt inhibitory factor-1 6.1
IDP 6.1
linker for activation of T cells 6.1
PGN 6.1
HRAS 6.1
Rho kinase 6.1
promyelocytic leukemia protein 6.1
Gem 6.1
RGS2 6.1
F(1)-ATPase 6.1
ABCE1 6.0
p39 6.0
phosphomonoesterase 6.0
cell cycle protein 6.0
PIK3R1 6.0
hOGG1 6.0
pheromone receptor 6.0
LIM kinase 6.0
serine-threonine protein kinase 6.0
Aurora kinase A 6.0
HM1 6.0
small GTPase 6.0
ULK1 6.0
ARF6 6.0
PI-3 kinase 6.0
GBL 6.0
Mg(2+)-ATPase 6.0
CXCR-4 6.0
AURKA 6.0
EF-Tu 6.0
OAT1 5.9
spastin 5.9
MM1 5.9
collagen VII 5.9
NuMA 5.9
endosomal protein 5.9
WNT5A 5.9
SKP1 5.9
P42 5.9
BCH 5.9
PBD 5.9
contractile protein 5.9
choline transporter 5.9
carboxypeptidase E 5.9
LAMP-1 5.9
LDHA 5.9
nexin 5.9
ENT1 5.9
folliculin 5.9
proline rich 5.9
VMAT2 5.8
more...
Disease
Morris Hepatoma 9.6
XRN 9.4
Rinderpest 9.0
cHL 9.0
GCS1 8.8
Carpenter syndrome 8.6
audiogenic epilepsy 8.3
Neovascular age-related macular degeneration 8.3
HPC1 8.3
cardiofaciocutaneous syndrome 8.0
NS3 7.9
OPA1 7.8
HOPS 7.6
Shope fibroma 7.1
Costello syndrome 7.1
RGS 7.1
RAT 7.1
audiogenic seizure 7.0
Aeromonas hydrophila infection 7.0
CGD 6.5
AD1 6.5
Degos 6.3
vaccinia 6.2
megakaryocytic leukemia 6.2
BEN 6.1
chondrolysis 6.0
spondyloepiphyseal dysplasia 6.0
PBD 6.0
idiopathic thrombocytopenic purpura 6.0
West Nile Virus 5.9
Liver regeneration 5.8
Fallopian tube 5.8
Sutton 5.8
thyroid adenoma 5.7
Hereditary spastic paraplegia 5.7
Kartagener's syndrome 5.7
Sander 5.7
Lesch-Nyhan syndrome 5.6
Recklinghausen 5.6
Pleomorphic adenoma 5.6
dumping syndrome 5.6
MEN 2B 5.5
hairy leukoplakia 5.5
benign nevi 5.5
HPC 5.5
myeloblastosis 5.4
TTP 5.4
amebic colitis 5.4
Joubert syndrome 5.4
Classical swine fever 5.3
optic atrophy 5.2
Zinc deficiency 5.2
PPP 5.2
Ductal 5.1
African swine fever 5.1
Japanese encephalitis 5.0
neurofibromatosis type 1 4.9
inflammatory breast cancer 4.9
cutis laxa 4.9
Crouzon syndrome 4.9
dengue 4.9
TTP 4.9
Lennox-Gastaut syndrome 4.8
Apert syndrome 4.8
BCH 4.8
COL2A1 4.8
molluscum contagiosum 4.8
lipid disorder 4.7
Small cell carcinoma 4.7
Lennox-Gastaut syndrome 4.6
NS2 4.6
magnesium deficiency 4.6
Hypertrophic 4.6
Hermansky-Pudlak syndrome 4.6
HCI 4.6
viral diarrhea 4.5
hepatitis C 4.5
Hypertrophic cardiomyopathy 4.5
self-injurious behavior 4.4
Cholangiocarcinoma 4.4
PTP 4.4
Bowen's disease 4.4
legionellosis 4.4
Anisakis 4.4
protein deficiency 4.3
acute pulmonary edema 4.3
Roth 4.3
Venezuelan equine encephalitis 4.3
Moore 4.2
hereditary spherocytosis 4.2
Legionella 4.2
Colon cancer 4.2
neurofibromatosis 4.2
yellow fever 4.1
thiamine deficiency 4.1
metachromatic leukodystrophy 4.0
PIN 4.0
adenomyosis 3.9
chemical carcinogenesis 3.9
retinopathy of prematurity 3.9
MMA 3.9
spastic paraplegia 3.8
Human immunodeficiency virus type 3.8
Mitchell 3.8
renal cyst 3.8
pertussis 3.8
hepatitis E 3.8
lymphangioleiomyomatosis 3.7
uveal melanoma 3.7
Recruitment 3.7
macrocephaly 3.7
tonsillitis 3.7
Wells 3.7
SMS 3.7
desmoid 3.6
craniosynostosis 3.6
stomatitis 3.6
FBS 3.5
familial Mediterranean fever 3.5
Sarcoma 3.5
Sarcoma 3.5
skin tumor 3.5
tuberous sclerosis 3.5
Dissociation 3.5
epithelial tumor 3.4
Robinson 3.4
subacute sclerosing panencephalitis 3.3
EBV infection 3.3
bronchiectasis 3.2
Wiskott-Aldrich syndrome 3.2
keratosis 3.2
proliferative diabetic retinopathy 3.2
chikungunya 3.2
PIN 3.2
MAS 3.2
polycystic kidney 3.1
Yersinia 3.1
pseudotuberculosis 3.1
ovarian cysts 3.1
PDE 3.0
CNS diseases 3.0
disorientation 3.0
retinitis pigmentosa 3.0
narcolepsy 3.0
dyskinesia 3.0
chronic granulomatous disease 3.0
hairy cell leukemia 3.0
Chagas 2.9
gastroenteritis 2.9
pancreatic cancer 2.8
ARF 2.8
carcinogenesis 2.8
Mycoplasma 2.8
Charcot-Marie-Tooth disease 2.8
sinusitis 2.8
Graves' disease 2.8
Shigella flexneri 2.8
hypercholesterolemia 2.8
AAA 2.8
BLM 2.8
dilated cardiomyopathy 2.8
invasive cancer 2.8
Brucella abortus 2.7
Hepatocellular carcinoma 2.7
mammary tumor 2.7
infectious mononucleosis 2.6
cholera 2.6
pemphigus 2.6
neuroblastoma 2.6
lymphocytosis 2.6
vitiligo 2.6
herpes simplex 2.6
hemorrhagic fever 2.6
astrocytoma 2.6
toxoplasmosis 2.6
Wright 2.5
opportunistic infection 2.5
glioblastoma 2.5
impotence 2.5
warts 2.5
Marfan syndrome 2.5
cutaneous melanoma 2.5
renal cell carcinoma 2.5
epiphysis 2.4
B-cell lymphomas 2.4
myeloid leukemia 2.4
leukemogenesis 2.4
tumorigenesis 2.3
dermatomyositis 2.3
sarcoma 2.3
familial adenomatous polyposis 2.2
glioma 2.2
Hippel 2.2
movement disorder 2.2
Prostate Cancer 2.2
brain edema 2.2
Huntington's disease 2.2
Blocking 2.2
neurological disease 2.2
multiple endocrine neoplasia 2.2
thymoma 2.2
autoimmune disease 2.1
renal cancer 2.1
chronic bronchitis 2.1
SCH 2.0
DBA 2.0
papilloma 2.0
acute hepatitis 2.0
cardiomyopathy 2.0
Parkinson's disease 2.0
mental retardation 2.0
mental retardation 2.0
pulmonary edema 2.0
Placenta 1.9
hepatocellular carcinoma 1.9
oral cancer 1.9
SDS 1.9
worms 1.9
enteritis 1.9
scleroderma 1.9
liver cancer 1.9
epithelial ovarian cancer 1.8
sickle cell disease 1.8
uremia 1.8
mole 1.8
Adhesion 1.8
rubella 1.8
Burkitt's lymphoma 1.8
West 1.8
temporal lobe epilepsy 1.7
acute renal failure 1.7
aortic regurgitation 1.7
drug addiction 1.7
amyotrophic lateral sclerosis 1.7
PDB 1.6
tumor progression 1.6
erectile dysfunction 1.6
fatty liver 1.6
ovarian cancer 1.6
mole 1.6
pheochromocytoma 1.5
hypertrophic cardiomyopathy 1.5
diphtheria 1.5
Mycobacterium 1.5
glomerulosclerosis 1.5
myasthenia gravis 1.5
liver cancer 1.5
cold 1.4
Duchenne muscular dystrophy 1.4
rabies 1.4
melanoma 1.4
metastatic breast cancer 1.4
acute promyelocytic leukemia 1.4
head and neck cancer 1.4
wasting 1.4
virus infection 1.4
developmental delay 1.4
liver fibrosis 1.3
epididymis 1.3
meningioma 1.3
osteosarcoma 1.3
diabetic retinopathy 1.3
herpes 1.3
scoliosis 1.3
abdominal aortic aneurysm 1.3
PHA 1.3
Kaposi's sarcoma 1.2
chronic liver disease 1.2
heart failure 1.2
genetic disorder 1.2
encephalitis 1.2
pulmonary hypertension 1.2
chronic myeloid leukemia 1.1
SARS 1.1
colon cancer 1.1
ureter 1.1
chronic pain 1.1
prostate cancer 1.1
gastritis 1.1
Hodgkin's disease 1.0
immunodeficiency 1.0
viremia 1.0
lymphoma 1.0
hyperthyroidism 1.0
hyperinsulinemia 1.0
acute lymphoblastic leukemia 0.9
chronic lymphocytic leukemia 0.9
carcinoma 0.9
retinoblastoma 0.9
malaria 0.9
uterus 0.9
inflammatory bowel disease 0.8
prolapse 0.8
tumor growth 0.8
subarachnoid hemorrhage 0.8
myopathy 0.8
tumor 0.8
Epstein 0.8
brain tumor 0.8
aggressiveness 0.8
skin disease 0.7
Chlamydia 0.7
ATM 0.7
celiac disease 0.7
bacteremia 0.7
breast cancer 0.6
dyslipidemia 0.6
hydrocephalus 0.6
bipolar disorder 0.5
chronic lymphocytic leukemia 0.5
lung cancer 0.5
malnutrition 0.5
essential hypertension 0.5
systemic lupus erythematosus 0.5
respiratory failure 0.5
Leukemia 0.5
cancer 0.5
ischemia 0.5
tuberculosis 0.4
Haemophilus 0.4
leukemia 0.4
endocarditis 0.4
dysphagia 0.4
hyperlipidemia 0.4
autism 0.4
dysplasia 0.4
lung disease 0.3
bladder cancer 0.3
B-cell lymphoma 0.3
infectious diseases 0.3
migraine 0.3
fungal infection 0.3
vascular disease 0.3
adenocarcinoma 0.3
ulcerative colitis 0.3
metastases 0.3
sepsis 0.3
neutropenia 0.2
plaque 0.2
encephalopathy 0.2
Infection 0.1
influenza 0.1
osteoporosis 0.1
type 2 diabetes 0.1
sepsis 0.1
chronic hepatitis 0.1
primary tumor 0.0
psoriasis 0.0
cirrhosis -0.0
adenoma -0.0
Crohn's disease -0.1
major depressive disorder -0.1
squamous cell carcinoma -0.1
Klebsiella -0.1
lupus -0.1
non-small cell lung cancer -0.1
chronic renal failure -0.1
neuropathy -0.2
SEM -0.2
cornea -0.2
lung carcinoma -0.2
proteinuria -0.2
congestive heart failure -0.2
obesity -0.3
infertility -0.3
Alzheimer's disease -0.4
asthma -0.4
MCF -0.4
HIV -0.4
cytomegalovirus -0.5
aggression -0.5
hyperglycemia -0.5
chronic obstructive pulmonary disease -0.5
hepatitis -0.5
liver disease -0.6
myocardial ischemia -0.6
fits -0.6
epilepsy -0.6
heart disease -0.7
diabetes -0.7
gastric cancer -0.8
GSH -0.9
hepatitis B -0.9
coronary artery disease -1.1
renal disease -1.1
rheumatoid arthritis -1.3
pneumonia -1.4
dementia -1.4
myocardial infarction -1.7
arthritis -1.7
hypertension -2.0
depression -2.0
AIDS -2.5
stroke -2.8
Symptom
male subfertility 6.3
rundown 5.4
fasciculation 4.0
menopausal symptoms 3.7
twitching 3.3
masculinization 3.0
starvation 2.7
cachexia 1.9
hypotonia 1.8
flushing 1.7
spasticity 1.7
collapse 1.5
spasm 1.5
dystonia 1.3
splenomegaly 1.1
anorexia 0.6
acidity 0.5
ataxia 0.4
seizures 0.4
hypothermia 0.3
angina -0.0
fatigue -0.3
weakness -0.9
anesthesia -1.4
pain -2.6
Drug
Sinefungin 8.6
Coal tar 8.4
Domin 7.9
Mizoribine 7.7
Hydergine 7.5
Carbidopa 7.0
Malachite Green 6.9
Spiegel 6.5
RAL 6.4
Pyridoxal 6.3
Alanine 6.1
Methylprednisolone 5.5
Papaverine 5.5
Sinemet 5.3
Ouabain 5.1
Pravastatin 4.7
Adenosine triphosphate 4.5
DFP 4.5
Parkin 4.5
Parkin 4.5
Isoniazid 4.4
CDP 4.2
Vitamin B 4.1
ZnCl2 4.0
ZnCl2 4.0
Lovastatin 4.0
BLM 3.9
Glycyrrhiza 3.9
IFN-beta 3.8
Amiloride 3.8
Acacia 3.7
Simvastatin 3.7
Amiloride 3.5
-deoxyadenosine 3.3
NAG 3.3
NADH 3.2
G418 3.2
Herceptin 3.2
Fragment 3.2
Asn 3.2
TAT 3.1
ETS 3.0
ICI 3.0
Ringer's solution 2.9
lysine 2.8
CaCl2 2.7
CaCl2 2.7
Taxol 2.7
CaCl2 2.7
Gel 2.5
p75 2.4
Spectrum 2.4
Ethanol 2.1
FAD 1.9
Histamine 1.9
Bifidobacterium 1.8
MAP 1.4
Spectrum 1.4
ABC 1.2
citric acid 1.1
ZnO 0.6
vitamin E 0.2
Nephron 0.2
caffeine -0.1
Asthma -0.3
IFN-gamma -0.5
IL-2 -0.5
CSF -0.6
Dermatol -0.7
Enzyme
adenylylsulfate-ammonia adenylyltransferase 14.3
triphosphatase 14.3
EC 3.6.1.16 14.3
EC 3.6.1.28 13.3
EC 3.6.2.1 13.3
EC 3.6.1.29 13.3
nucleoside triphosphate phosphohydrolase 12.3
EC 3.6.1.17 11.6
NS protease 11.3
Protein 2 10.9
EC 2.7.4.15 10.9
dGTPase 10.2
Dol-P phosphatase 9.9
Ap4A hydrolase 9.8
dTTPase 9.6
GDPase 9.5
i-AAA protease 9.5
dCTP deaminase 9.2
nicotinamide adenine dinucleotide glycohydrolase 9.0
dCTP deaminase 9.0
ATPase 8.9
m-AAA protease 8.8
ADPase 8.7
beta-glycerophosphatase 8.6
trimetaphosphatase 8.6
poly(A)-specific ribonuclease 8.5
dolichol kinase 8.4
DIPP 8.4
EC 3.6.1.1 8.2
nucleoside diphosphokinase 8.0
poly(A)-specific ribonuclease 8.0
exopolyphosphatase 7.9
gluconate dehydrogenase 7.9
thiamine pyrophosphokinase 7.7
elongation factor (EF) 7.7
glycerol-3-phosphate oxidase 7.7
nucleotidase 7.5
CTD kinase 7.2
5'-nucleotidase 7.2
endonuclease V 7.2
ATP diphosphohydrolase 7.1
poly(A) polymerase 7.0
dCMP deaminase 6.9
glucose-6-phosphatase 6.7
p-nitrophenylphosphatase 6.6
succinic dehydrogenase 6.6
apyrase 6.6
exonuclease I 6.5
proton-translocating ATPase 6.5
acylphosphatase 6.5
histidase 6.5
glycine decarboxylase 6.2
Mg2+-ATPase 6.1
cGMP phosphodiesterase 6.0
callose synthase 6.0
inositol phosphatase 6.0
nitrile hydratase 5.9
deoxyribonuclease 5.8
sphingosine kinase 5.8
deoxyribonuclease 5.8
carboxypeptidase E 5.7
3'-exonuclease 5.7
dUTPase 5.7
NAD glycohydrolase 5.6
venom phosphodiesterase 5.5
adenylate kinase 5.4
3-hydroxy-3-methylglutaryl coenzyme A reductase 5.4
calcium pump 5.4
CNPase 5.3
succinate dehydrogenase 5.3
p80 5.2
myosin ATPase 5.2
pyruvate kinase 5.2
acid phosphatase 5.2
transcriptase 5.0
polynucleotide kinase 5.0
3-hydroxyacyl-CoA dehydrogenase 4.9
phosphatidylinositol 4-kinase 4.9
3-hydroxyacyl-CoA dehydrogenase 4.9
cholesterol oxidase 4.9
deoxycytidine kinase 4.9
transhydrogenase 4.9
purine nucleoside phosphorylase 4.9
glucokinase 4.9
transpeptidase 4.8
alanine aminopeptidase 4.8
phosphoinositide 3-kinase 4.8
phospholipase D 4.8
lactic acid dehydrogenase 4.8
RNA polymerase 4.7
gamma-glutamyl transpeptidase 4.7
arginine deiminase 4.6
subtilisin 4.6
MEKK1 4.5
adenosine kinase 4.5
thermolysin 4.5
adenylate cyclase 4.4
glucose-6-phosphate dehydrogenase 4.4
isocitrate lyase 4.4
phytase 4.4
phytase 4.4
kinesin 4.4
protein phosphatase 2A 4.4
PTPase 4.4
ADP-ribosyltransferase 4.4
NADPH oxidase 4.3
ADP-ribosyltransferase 4.3
DNase 4.3
fumarase 4.2
NADPH oxidase 4.2
malate dehydrogenase 4.2
ATP synthase 4.1
diaphorase 4.1
uricase 4.1
xanthine dehydrogenase 4.1
cellulose synthase 4.0
CPR 4.0
hexokinase 4.0
phosphodiesterase 4.0
phosphatidylinositol 3-kinase 3.9
6-phosphogluconate dehydrogenase 3.8
6-phosphogluconate dehydrogenase 3.8
TOR 3.8
citrate synthase 3.8
protein kinase 3.7
ricin 3.7
transglutaminase 3.7
phospholipase C 3.6
guanylate cyclase 3.6
DNA polymerase 3.6
phosphoenolpyruvate carboxylase 3.6
glycerol-3-phosphate dehydrogenase 3.6
cytochrome oxidase 3.6
cathepsin G 3.5
glycerol-3-phosphate dehydrogenase 3.5
cathepsin K 3.5
MPP 3.5
TdT 3.5
beta-glucuronidase 3.4
phosphofructokinase 3.4
cathepsin D 3.3
NADH dehydrogenase 3.3
glutamate dehydrogenase 3.3
phosphoglycerate kinase 3.3
glutamate dehydrogenase 3.2
ribonuclease 3.2
ribonuclease 3.2
matrix metalloproteinase 9 3.2
CAD 3.2
glutamate dehydrogenase 3.2
PDK1 3.2
caspase-8 3.2
TAT 3.1
alkaline phosphatase 3.1
histidine kinase 3.1
mitogen-activated protein kinase 3.1
deaminase 3.0
lactate dehydrogenase 3.0
myosin light chain kinase 2.9
RNase 2.9
DNA ligase 2.9
DNA ligase 2.9
RNase H 2.9
diaphorase 2.9
firefly luciferase 2.9
micrococcal nuclease 2.9
calcineurin 2.9
complex I 2.8
RNase 2.8
carboxylesterase 2.8
isocitrate dehydrogenase 2.7
glutathione S-transferase 2.7
trypsin 2.7
protein kinase C 2.7
isocitrate dehydrogenase 2.6
aldolase 2.6
hexosaminidase 2.6
thymidylate synthase 2.5
nitrogenase 2.5
MEK 2.5
NOS 2.5
PDE 2.5
MAP 2.5
enolase 2.5
caspase-9 2.5
NADPH-diaphorase 2.4
CaMKII 2.4
AMPK 2.3
cdc2 2.3
cathepsin B 2.3
phosphoenolpyruvate carboxykinase 2.3
phosphoenolpyruvate carboxykinase 2.3
alpha-glucosidase 2.3
MMP 2.3
CAD 2.2
CAD 2.2
CPT 2.2
alcohol dehydrogenase 2.2
phosphoenolpyruvate carboxykinase 2.2
IKK 2.1
invertase 2.1
topoisomerase 2.1
DNA methyltransferase 2.1
adenosine deaminase 2.0
adenosine deaminase 2.0
chymotrypsin 1.9
demethylase 1.9
phosphorylase 1.9
proteasome 1.9
NQO1 1.7
endonuclease 1.7
focal adhesion kinase 1.7
AMPK 1.7
ornithine decarboxylase 1.7
aldehyde dehydrogenase 1.7
papain 1.7
ERK 1.6
lipoprotein lipase 1.6
urease 1.5
superoxide dismutase 1.5
tyrosine hydroxylase 1.5
carbonic anhydrase 1.5
urease 1.5
thymidine kinase 1.5
xanthine oxidase 1.3
pepsin 1.3
elastase 1.2
topoisomerase 1.2
acetylcholinesterase 1.1
reverse transcriptase 1.0
monoamine oxidase 1.0
thrombin 0.9
caspase-3 0.8
cholinesterase 0.7
luciferase 0.7
AMP-activated protein kinase 0.7
P-glycoprotein 0.6
PARP 0.6
catalase 0.6
phospholipase A2 0.5
neuraminidase 0.5
beta-galactosidase 0.5
renin 0.2
lipase 0.2
creatine kinase 0.1
lysozyme -0.0
aspartate aminotransferase -0.1
ACS -0.3
alanine aminotransferase -0.4
peroxidase -1.7
Compound
3-hydroxybenzonitrile 12.3
Chlormerodrin 12.0
GppppG 11.5
Deoxyuridine 11.2
Kirromycin 10.8
Purine riboside 10.5
Thiamine triphosphate 10.0
Thiamine triphosphate 10.0
benzyl thiocyanate 9.6
Methapyrilene 9.0
dIMP 9.0
Pinitol 8.6
Thiostrepton 8.5
dITP 8.4
GAP 8.4
Azocoll 8.2
Adenosine 8.2
Adenine arabinoside 8.1
XTP 8.0
dGTP 8.0
Etorphine 7.9
ITP 7.8
dCDP 7.7
Sodium deoxycholate 7.7
Resazurin 7.5
dUDP 7.5
Triphosphate 7.4
dADP 7.4
Pantoprazole 7.2
dATP 7.2
CTP 7.2
Vinyl chloride 7.1
Dolichol 7.1
TTP 7.1
XMP 7.0
UTP 7.0
Fusidic acid 6.9
3'-AMP 6.9
Monocrotaline 6.8
Guo 6.8
7-methylguanosine 6.7
GTP 6.7
P2A 6.7
PPi 6.7
Thiamine 6.7
ribose-5-phosphate 6.7
GMP 6.6
dUMP 6.6
tetraphosphate 6.5
Ara-A 6.4
Rottlerin 6.4
TDP 6.4
dCTP 6.4
Cyproterone acetate 6.4
Rottlerin 6.3
Rottlerin 6.3
Pyridoxal 6.3
Beryllium 6.3
Inosine 6.3
dGMP 6.3
GDP 6.3
Deoxycholic acid 6.2
Cyanogen bromide 6.2
1,2,3,4-tetrahydronaphthalene 6.2
PGA2 6.1
methylguanosine 6.1
Alanine 6.1
Cordycepin 6.1
Cordycepin 6.1
Cordycepin 6.1
IDP 6.1
NEM 6.0
PBD 6.0
Fluvoxamine 5.9
Mg2+ 5.9
Guo 5.9
Rhodopsin 5.9
quinuclidine 5.9
quinuclidine 5.9
Triton WR-1339 5.8
FMLP 5.8
ethanesulfonic acid 5.8
ethanesulfonic acid 5.8
Gold, 5.7
Gold, 5.7
Gold, 5.7
CNA 5.7
TBC 5.7
Methylprednisolone 5.6
HPC 5.6
HPC 5.6
Suramin 5.5
DCC 5.5
Papaverine 5.5
Malachite Green 5.5
3-hydroxyanthranilic acid 5.4
NPP 5.4
Ruthenium red 5.3
Cysteamine 5.3
ADP 5.3
40S 5.2
adenylate 5.2
11-cis-retinal 5.2
Pravastatin 5.2
Camptothecin 5.1
Camptothecin 5.1
Camptothecin 5.1
DBD 5.1
Deoxyribonucleic acid 5.1
dCMP 5.1
Ouabain 5.0
ADP 5.0
ADP 5.0
DEN 5.0
ATP 4.9
Phosphatidylinositol 4.9
DCB 4.9
HPT 4.9
dUTP 4.9
Praziquantel 4.9
Sevoflurane 4.9
glucose-6-phosphate 4.9
Lovastatin 4.9
Guanine 4.9
manganese 4.8
DEP 4.8
isonicotinic acid 4.8
BaCl2 4.8
3-methylhistidine 4.7
Vitamin D3 4.7
CDP 4.7
MgCl2 4.7
NiCl2 4.6
pyridazine 4.6
pyridazine 4.6
Thapsigargin 4.6
Vitamin D3 4.6
MAL 4.5
Elastin 4.5
dimethylarsinic acid 4.5
dimethylarsinic acid 4.5
dimethylarsinic acid 4.5
dimethylarsinic acid 4.5
adenosylmethionine 4.5
dimethylarsinic acid 4.4
DEP 4.4
TCDD 4.4
Paraquat 4.4
Genistein 4.3
uridine 4.3
dimethylarsinic acid 4.3
nicotinamide 4.3
Paraquat 4.2
L-T3 4.2
DNP 4.2
Wortmannin 4.2
TPP 4.2
HCI 4.2
Glycogen 4.1
fMet 4.1
MK801 4.0
Arachidonic acid 4.0
Triton X-100 4.0
PAR 4.0
PAM 4.0
PAM 4.0
MES 4.0
MES 4.0
AMP 4.0
DAB 3.9
Thymidine 3.9
S-adenosylhomocysteine 3.9
MMA 3.9
DAMP 3.9
HMG-CoA 3.9
Histidine 3.8
BUdR 3.8
Amiloride 3.8
phosphate 3.8
guanidine 3.8
PIN 3.8
Actinomycin D 3.7
IMP 3.7
8-OHdG 3.7
CCP 3.7
Tetracycline 3.7
alanine 3.7
ANS 3.6
ANS 3.6
MMA 3.6
HVA 3.6
hydroxylamine 3.6
C2H2 3.5
Cbl 3.5
cobalt 3.5
Naloxone 3.5
hydroxylamine 3.5
DEAE 3.5
Luminal 3.5
threonine 3.5
Tyrosine 3.4
Cytochrome c 3.4
Methionine 3.4
PMA 3.4
Tween 20 3.4
DTT 3.4
UDP 3.3
2-mercaptoethanol 3.3
TMP 3.3
EDTA 3.3
Colchicine 3.3
EDTA 3.3
PPI 3.3
DTT 3.3
TAR 3.3
Rifampicin 3.3
APS 3.3
NADH 3.2
pyrimidine 3.2
rubidium 3.2
Tris 3.2
TTC 3.2
pyrimidine 3.2
Cobalt 3.2
Leucine 3.1
MMA 3.1
CCl4 3.1
DPP 3.1
tryptophan 3.1
tryptophan 3.1
COS 3.0
Vimentin 3.0
phosphoserine 3.0
Tris 3.0
tryptophan 3.0
tyrosine 3.0
Malondialdehyde 3.0
lysine 3.0
CIT 2.9
serine 2.9
NADPH 2.9
NADPH 2.9
BLM 2.9
CIT 2.9
Oxytocin 2.9
glycerol 2.8
AAA 2.8
ADP-ribose 2.8
glutamine 2.8
tryptophan 2.8
Nifedipine 2.8
TCA 2.8
cysteine 2.8
PMA 2.8
Sodium 2.7
Asp 2.7
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 2.7
Quercetin 2.7
MEK 2.7
ICI 2.7
Trypsin 2.7
CaCl2 2.7
Cholesterol 2.6
Metformin 2.6
Rapamycin 2.6
calcium 2.6
acrylamide 2.6
His 2.6
Metformin 2.6
INH 2.6
Optimal 2.6
SCN 2.6
arginine 2.5
cAMP 2.5
potassium 2.5
methionine 2.5
propylene glycol 2.5
sodium 2.5
PDB 2.5
chloroform 2.5
Neuronal 2.5
L-carnitine 2.5
DBA 2.5
Salix 2.4
asparagine 2.4
propylene glycol 2.4
alloxan 2.4
Propranolol 2.4
cyanide 2.3
Propranolol 2.3
Triton 2.3
alcohol dehydrogenase 2.3
Adrenal 2.3
Phe 2.3
Thrombin 2.3
Dopamine 2.2
NAD 2.2
stearic acid 2.2
stearic acid 2.2
DBA 2.2
2-hydroxyethyl 2.2
2-hydroxyethyl 2.2
2-hydroxyethyl 2.2
2-hydroxyethyl 2.2
2-hydroxyethyl 2.2
2-hydroxyethyl 2.2
2-hydroxyethyl 2.2
salt 2.2
DBA 2.2
aflatoxin B1 2.2
stearic acid 2.2
leucine 2.2
Insulin 2.2
MAP 2.1
thiourea 2.1
MDA 2.1
Histone 2.1
Gly 2.1
zinc 2.1
phosphocreatine 2.1
NO3 2.0
Cyclosporine 2.0
phosphoric acid 2.0
MPTP 2.0
gamma-aminobutyric acid 2.0
SDS 2.0
APAP 1.9
HCl 1.9
piperazine 1.9
Cortisol 1.9
FAD 1.9
DNA 1.9
2-hydroxyethyl 1.9
Histamine 1.9
cadmium 1.8
sulfate 1.8
Dexamethasone 1.8
pentose 1.8
PLA 1.7
pentose 1.7
superoxide radical 1.7
urea 1.7
pentose 1.7
Melatonin 1.7
pyrene 1.7
glutamate 1.6
NAD 1.6
NH2 1.6
pentose 1.6
Isoproterenol 1.6
Lactate 1.6
palmitic acid 1.6
cGMP 1.6
aluminum 1.6
acetone 1.5
bromide 1.5
Sucrose 1.5
valine 1.5
prostaglandin E1 1.5
2-oxoglutarate 1.5
A 3 1.5
benzoic acid 1.4
phosphorus 1.4
formaldehyde 1.4
proline 1.4
TNM 1.4
Phytol 1.4
Phytol 1.4
DMSO 1.4
glutamic acid 1.3
Salt 1.3
nitrate 1.2
ACh 1.2
AMPA 1.1
acetate 1.1
formaldehyde 1.1
palmitic acid 1.1
oxalate 1.0
formic acid 1.0
formic acid 1.0
formic acid 1.0
formic acid 1.0
formic acid 1.0
formic acid 1.0
formic acid 1.0
formic acid 1.0
formic acid 1.0
formic acid 1.0
nickel 1.0
aspartic acid 1.0
Ile 1.0
aspartic acid 1.0
oxygen 1.0
Diabetol 1.0
N-acetylcysteine 0.9
NADP 0.9
sodium chloride 0.9
GABA 0.9
aspartic acid 0.8
GABA 0.8
naphthalene 0.8
tin 0.8
acetic acid 0.8
hyaluronic acid 0.7
ammonium 0.7
aspartic acid 0.7
prostacyclin 0.6
Cereb 0.6
PGE2 0.5
carbonate 0.5
hexane 0.4
TSH 0.4
glucose 0.4
5-HT 0.4
chlorine 0.4
barium 0.4
iodine 0.3
Pac 0.3
fluorine 0.3
Dec 0.2
boron 0.2
vinyl 0.2
galactose 0.2
nitrogen 0.1
TOF 0.0
hydrogen 0.0
MIC -0.0
caffeine -0.1
TEM -0.2
retinoic acid -0.2
aldosterone -0.2
ACS -0.3
ACS -0.3
phenol -0.3
ethanol -0.4
creatinine -0.5
methanol -0.5
TNF -0.6
MTT -0.6
acetonitrile -0.6
nitric oxide -0.7
noradrenaline -0.7
water -0.7
PEG -0.9
GSH -1.0
GSH -1.0
copper -1.2
PEG -1.4
silver -1.5
iron -1.7
Clin -1.9
Cardiol -1.9
CO2 -2.1