Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.5.4.4 (
adenosine deaminase
)
5,136
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Trazodone
, a nontricyclic antidepressant drug, is a noncompetitive inhibitor of
adenosine deaminase
. The specific activity of
adenosine deaminase
in rat brain cortex homogenate is 140 +/- 15 (SEM) nm/min/gm tissue, while the apparent Km of adenosine is 77 microM. The apparent Ki of trazodone for the brain cortex enzyme is 1 X 10(-4)M, and 6 X 10(-5)M for purified calf intestine mucosal enzyme.
...
PMID:Trazodone, a nontricyclic antidepressant, is an inhibitor of adenosine deaminase. 398 68
