Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.5.4.4 (
adenosine deaminase
)
5,136
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Title compounds were synthesized from the protected beta-D-ribofuranosyl-1-azide, the sodium salt of
malononitrile
and the suitable aroyl nitrile. The deblocked 8-azaadenosines had shown good activity as inhibitors of
adenosine deaminase
(
ADA
) and a non-substrate behaviour toward the hydrolytic deamination promoted by the enzyme.
...
PMID:Synthesis and ADA inhibitory activity of new 2-aryl-8-azaadenosines. VIII. 138
