Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.5.4.4 (adenosine deaminase)
 5,136 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The activity of adenosine deaminase has been measured in 295 specimens of pleural fluid from 248 patients. The effusions were due in part to pleural tubercle (n = 8), rheumatoid arthritis (n = 2) empyema (n = 4), or malignant lymphoma (n = 5); the remainder were due to effusions of other aetiologies (n = 229). The disorders of the first group of patients are known to be associated with an elevated level of ADA. The two groups of patients were compared by fixing the upper limit of normal at 50 U/l. There was a 97% specificity even though the sensitivity was only 42%. However the relative smallness of the group of patients who were suffering from tuberculosis, rheumatoid arthritis, empyema and malignant lymphoma means that the interpretation of the sensitivity of the test should be subject to caution.
Rev Mal Respir 1988
PMID:[Determination of adenosine deaminase in 295 samples of pleural fluid]. 321 97

We report the case of a 38-year-old woman, born and raised in Congo, in France for 7 years, who developed ascites 2 months after delivery by C-section. Thrombopenia at 95,000 elements per millimeter cube was diagnosed during her pregnancy and her obstetrician initiated a treatment with corticosteroids. Analysis of the ascitic fluid showed a high concentration of proteins (55.7 g/l), with 2000 elements, 80% of which were lymphocytes, and very high levels of adenosine deaminase. Thoracoabdominal tomodensitometry revealed ascites, a multinodular spleen, and hyperemia of the peritoneum; but the liver and the lungs were normal and no adenoma was identified. Laparoscopy was not performed and the suspected diagnosis of peritoneal tuberculosis was confirmed by only one culture of ascitic fluid.
Med Mal Infect 2010 Jul
PMID:[Ascites with high protein concentration 2 months after C-section delivery: diagnosis using adenosine deaminase analysis combined with iconography]. 1985 15