Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.4.17 (adenosine deaminase)
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Human Gene/Protein
adenosine deaminase 12.6
Adenosine deaminase protein 12.6
mutant adenosine deaminase 12.0
MHC class I HLA-B 11.6
dsRAD 11.6
ubiquitin-conjugating enzyme E2Q family member 1 11.6
cat eye syndrome chromosome region, candidate 1 11.6
ADORA2 11.6
ADAT1 11.3
CECR1 11.3
ADAL 11.3
RNA editase 11.1
STRBP 11.0
ADAD2 11.0
ring finger protein 126 11.0
spermatid perinuclear RNA binding protein 11.0
dsRNA adenosine deaminase 10.8
adenosine kinase 10.8
ADA2 10.8
Adenosine deaminase 10.7
NICE-3 10.6
ADAR1 10.5
ADAR3 10.3
nucleoside phosphorylase 10.3
ADAR2 10.3
NICE1 10.3
AMP deaminase 10.2
ADAR 10.2
guanine deaminase 10.2
ADORA3 10.2
purine nucleoside phosphorylase 10.1
ADARB1 10.1
NICE-4 10.0
3',5'-cyclic AMP phosphodiesterase 10.0
AIH2 10.0
Na+/H+ exchanger isoform NHE-3 10.0
TENR 9.8
phosphoglucomutase 2 9.8
ADAT3 9.8
adenosine deaminase-like 9.8
guanine aminohydrolase 9.8
ADA 9.7
RNA adenosine deaminase 9.7
AdoHcyase 9.6
HBGR2 9.6
Kell blood group antigen 9.6
LALP1 9.6
interleukin 2 receptor gamma chain 9.6
adenylate kinase 3 9.6
Ribosomal protein S8 9.6
splicing factor proline/glutamine-rich 9.6
ecto-5'-nucleotidase 9.5
S-adenosylhomocysteine hydrolase 9.5
speriolin 9.4
POU domain class 5 transcription factor 1 9.4
adenosine monophosphate deaminase 9.4
Na+/nucleoside cotransporter 9.4
isoform L 9.4
Tenr 9.4
S100 calcium binding protein P 9.3
interleukin 27 9.3
ribosomal protein S26 9.3
ADARB2 9.3
GluR-B 9.2
Guanine deaminase 9.2
5'-nucleotidase 9.1
ENPP3 9.1
HLA-DRB3*01 9.1
FAP protein 9.0
TA5 9.0
GPBP 9.0
AMPD2 9.0
YF5 8.9
myoadenylate deaminase 8.9
DACT3 8.9
phosphoglucomutase 1 8.9
red cone pigment 8.9
AP-2 gamma 8.9
S100A7A 8.9
5' nucleotidase 8.8
more...
Disease
Gluthathione synthetase deficiency 12.6
Adenylate kinase deficiency 12.0
ADA-SCID 11.9
ADA deficiency 11.5
Tuberculous empyema 11.0
tuberculous effusion 10.5
Myoadenylate deaminase deficiency 10.4
tuberculous pleurisy 10.0
CLL variants 10.0
refractory hairy cell leukemia 10.0
Pseudochylothorax 10.0
alymphocytosis 9.8
stage IIIB breast cancer 9.8
PNP deficiency 9.7
Tuberculous meningoencephalitis 9.4
Tuberculous peritonitis 9.2
trisomy 20q 9.1
skin pigmentation disorder 8.9
Primary systemic vasculitis 8.9
congenital hemolytic anemia 8.7
secondary antibody deficiency 8.3
X-linked hypogammaglobulinemia 8.3
hereditary nonspherocytic hemolytic anemia 8.2
L.donovani 8.2
Milwaukee shoulder 8.2
Milwaukee shoulder 8.1
Pleural infection 7.9
congenital hypoplastic anemia 7.9
c-ALL 7.8
Frohlich 7.6
Combined immunodeficiency 7.5
gouty nephropathy 7.5
mouse leukemia L1210 7.4
antibody deficiency syndrome 7.3
Cutaneous polyarteritis nodosa 7.3
Hypothalamic hamartoma 7.2
X-linked severe combined immunodeficiency 7.2
reticular dysgenesis 7.2
prolymphocytic leukemia 7.2
SCID 7.2
Mycobacterium kansasii infection 7.1
Cyclic neutropenia 7.0
pleurisy 7.0
Hers 6.9
hypoplastic anemia 6.9
Pythiosis 6.9
KCS 6.8
erythroblastopenia 6.7
Tuberculous meningitis 6.7
Primary immunodeficiency 6.5
ML III 6.5
malignant pleural effusion 6.5
hairy cell leukemia 6.5
myocardial hypoxia 6.5
B cell neoplasms 6.4
enzyme deficiency 6.4
extrapulmonary tuberculosis 6.3
CML progression 6.3
infectious meningitis 6.3
ARTS 6.3
Anaplasmosis 6.3
APRT deficiency 6.3
immune deficiency 6.2
Lesch-Nyhan syndrome 6.2
Heck's disease 6.2
abdominal cyst 6.2
CPX 6.2
MODY1 6.1
Autoimmune encephalitis 6.0
WDHA syndrome 6.0
MODY 5.9
immunocytoma 5.8
refractory CLL 5.7
hypermethioninemia 5.7
erythroblastosis fetalis 5.6
HOA 5.6
Enzyme inhibition 5.6
early disease onset 5.5
viral meningitis 5.4
Sneddon's syndrome 5.4
more...
Symptom
Livedoid 6.9
bradypnea 5.9
Exercise intolerance 5.7
pleuritic chest pain 5.7
livedo 5.2
abdominal fullness 4.9
consciousness disturbance 4.5
non-productive cough 4.4
prostration 4.0
night sweats 3.9
lightheadedness 3.6
POA 3.5
swollen joints 3.5
hyperemesis gravidarum 3.5
Anoxia 3.5
neck stiffness 3.3
leg edema 3.2
clonus 3.1
splenomegaly 2.8
neurological disability 2.7
starvation 2.6
Hudson 2.5
productive cough 2.4
hypoproteinemia 2.4
functional recovery 2.3
tonic-clonic seizure 2.2
hypercapnia 2.2
nasal discharge 2.2
chest pain 2.1
nausea and vomiting 1.9
hypocapnia 1.9
exertional dyspnea 1.8
cough 1.8
hypotonia 1.6
anorexia 1.6
chronic cough 1.6
leg pain 1.6
dyspnea 1.5
Ill 1.5
exhaustion 1.4
nausea 1.4
tachypnea 1.3
hyperoxia 1.2
sore throat 1.1
seizures 1.1
dystonia 1.1
hypothermia 1.1
hoarseness 1.1
vomiting 0.9
spasticity 0.9
myalgia 0.9
dysarthria 0.7
abdominal pain 0.7
ataxia 0.6
apathy 0.6
sleepiness 0.5
chills 0.5
myoclonus 0.5
hepatosplenomegaly 0.5
diarrhea 0.5
acute stress 0.4
headache 0.4
fatigue 0.4
wheezing 0.4
paresthesia 0.3
shortness of breath 0.2
ENT 0.2
weakness 0.2
lethargy 0.1
hepatomegaly 0.1
hemoptysis -0.0
respiratory distress -0.1
angina -0.2
collapse -0.2
arthralgia -0.2
discomfort -0.3
discomfort -0.4
overweight -0.5
anesthesia -0.6
tremor -0.6
more...
Drug
Pegademase bovine 12.6
D-Eritadenine 12.6
Amdoxovir 11.2
Adenosine deaminase 10.9
Deoxyadenosine 10.7
Nipent 10.5
2'-Deoxyinosine 10.0
Formycin 9.8
Hexobendine 9.4
Acadesine 9.2
-deoxyadenosine 9.0
Ara-A 8.7
Nelarabine 8.6
Formycin B 8.4
Thyrogen 7.6
Propentofylline 7.2
Zinc sulfate 7.0
Zinc sulfate 7.0
Perhexiline 6.7
ddI 6.6
Levamisol 6.5
Adenosine triphosphate 6.2
Rolipram 6.2
Theophylline 6.1
Mizoribine 6.0
Poloxamer 5.9
Isoprinosine 5.8
Fludarabine 5.7
Rhubarb 5.6
PNT 5.5
Clofarabine 5.5
G418 5.5
FSH-beta 5.3
CFX 5.3
SrCl2 5.2
ETS 5.1
Salmon calcitonin 5.1
SrCl2 5.0
Abatacept 5.0
Forskolin 4.9
Cilostazol 4.9
Talc 4.8
Desferal 4.6
Glutamic acid 4.6
Nebivolol 4.5
Desferal 4.5
Rimonabant 4.2
Mycophenolic acid 4.2
Piracetam 4.1
caffeine 4.1
Secretin 4.1
CoCl2 3.9
CoCl2 3.9
Indomethacin 3.9
CTX 3.8
Scopolamine 3.8
Epigallocatechin 3.8
Glycerol 3.7
OMP 3.7
Papaverine 3.7
Emodin 3.7
GRF 3.6
Dihydro 3.5
CTC 3.5
Iloprost 3.5
DMAP 3.4
Emodin 3.4
Tuberculin 3.4
Viagra 3.4
Sulpiride 3.4
RFP 3.3
Glide 3.3
NH3 3.3
CTC 3.2
Kainic acid 3.2
Rutin 3.2
OTC 3.1
PMEA 3.1
Glucagon 3.0
balanced salt solution 3.0
more...
Enzyme
adenosine deaminase 12.6
adenosine deaminase 12.6
inosine nucleosidase 11.6
guanosine deaminase 11.3
AMP deaminase 10.9
adenosine kinase 10.9
deoxyadenosine kinase 10.9
adenine deaminase 10.8
ADPR-PPase 10.3
purine nucleoside phosphorylase 10.2
inosine kinase 10.1
AMP nucleosidase 10.0
guanase 9.9
imidazolonepropionase 9.8
adenosine nucleosidase 9.8
esterase D 9.3
phosphopentomutase 9.3
S-adenosyl-L-homocysteine hydrolase 9.2
5'-nucleotidase 9.1
adenine phosphoribosyltransferase 8.8
adenylosuccinate lyase 8.6
nucleotidase 8.5
GMP reductase 8.4
deoxyribose-5-phosphate aldolase 8.4
L-lysine alpha-oxidase 8.2
adenylosuccinate synthetase 8.2
deoxycytidine kinase 8.2
xanthine phosphoribosyltransferase 8.0
deoxyguanosine kinase 8.0
adenylate kinase 8.0
aldehyde dehydrogenase 7.9
PRPP synthetase 7.8
prolinase 7.8
AICAR transformylase 7.8
nucleotide pyrophosphatase 7.7
nucleoside phosphotransferase 7.7
penicillopepsin 7.6
phosphoglyceromutase 7.6
5'-methylthioadenosine nucleosidase 7.5
methylthioadenosine phosphorylase 7.5
deaminase 7.5
cytidine deaminase 7.3
phosphoglucomutase 7.3
inosine triphosphatase 7.3
IMP cyclohydrolase 7.3
DHOdehase 7.2
hypoxanthine-guanine phosphoribosyltransferase 7.2
apyrase 7.1
gluconate dehydrogenase 7.1
dipeptidyl peptidase IV 7.1
nucleoside hydrolase 7.1
phosphoglycolate phosphatase 7.0
6-phosphogluconate dehydrogenase 7.0
6-phosphogluconate dehydrogenase 7.0
S-adenosylhomocysteine nucleosidase 6.9
uridine kinase 6.9
nucleoside diphosphokinase 6.8
3'-phosphatase 6.8
ribokinase 6.7
dCMP deaminase 6.7
SPT 6.7
protein methylase II 6.6
nucleoside triphosphate phosphohydrolase 6.6
ribonucleotide reductase 6.6
IMP dehydrogenase 6.6
ribonucleotide reductase 6.5
tripeptidase 6.5
xanthine oxidase 6.4
UMP kinase 6.4
carboxypeptidase S 6.4
GMP synthetase 6.4
thymidine phosphorylase 6.3
CMP kinase 6.3
deoxycytidine deaminase 6.2
histidinol dehydrogenase 6.1
D-aspartate oxidase 6.0
xanthine dehydrogenase 6.0
mevalonate kinase 6.0
SsuE 6.0
SPT 5.9
more...
Compound
2,6-Diaminopurine ribonucleoside 12.6
C11H16N4O4 12.6
2-Azaadenosine 12.6
C11H16N4O4 12.6
2-Azaadenine 12.6
Coformycin 12.4
9-Deazaadenosine 11.6
Deoxycoformycin 11.5
5-Iodotubercidin 11.3
5-Iodotubercidin 11.3
5-Iodotubercidin 11.3
5-Iodotubercidin 11.2
8-Cyclopentyltheophylline 10.8
Deoxyadenosine 10.7
N6-Benzyladenosine 10.6
Substance B 10.6
N6-Benzyladenosine 10.6
2-Methyladenosine 10.6
nonyl 10.5
Purine riboside 10.4
2-Azahypoxanthine 10.3
6-Methoxypurine 10.3
1,4-dichloro-2-butyne 10.0
1,4-dichloro-2-butyne 10.0
bicyclo[3.1.0]hexan-2-ol 10.0
bicyclo[3.1.0]hexan-2-ol 10.0
bicyclo[3.1.0]hexan-2-ol 10.0
2-Chloroadenosine 9.9
2-Chloroadenosine 9.9
Stannic chloride 9.8
Stannic chloride 9.8
Stannic chloride 9.8
Neplanocin A 9.7
Formycin A 9.6
PADA 9.6
Ara-G 9.3
Ara-G 9.3
5'-Deoxyadenosine 9.3
1H-imidazole-4-carboxylic acid 9.3
Aristeromycin 9.1
C5H5NO 9.0
GAH 9.0
GMDP 9.0
Inosine 8.9
Diadenosine triphosphate 8.9
thieno[2,3-c]pyridine 8.8
C16H14N2O2 8.8
1,3-cyclopentanedicarboxylic acid 8.8
Fludarabine phosphate 8.8
Adenosine 8.8
Purine nucleoside 8.7
Adenine arabinoside 8.7
NBTGR 8.7
Sangivamycin 8.7
NBTGR 8.7
NBTGR 8.7
NBTGR 8.7
5-Methyluridine 8.6
6-Chloropurine 8.6
N-methyladenine 8.5
dipropyl 8.4
Formycin B 8.4
Sulmazole 8.4
Formycin B 8.4
cyclopentyl 8.3
Ara-A 8.3
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 8.3
D-ribose-1-phosphate 8.3
Cordycepin 8.3
Cordycepin 8.3
Cordycepin 8.2
ara-AMP 8.2
ara-AMP 8.2
dADP 8.2
Deoxyguanosine 8.2
dATP 8.0
MMPR 8.0
C5H8 8.0
Purine 7.9
Homocysteine thiolactone 7.9
more...