Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.5.4.17 (adenosine deaminase)
 5,206 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The activities of aspartate and alanine transaminase, serine dehydratase, arginase, glutamate dehydrogenase, adenylate deaminase and glutamine synthetase were determined in the stomach and small intestine of developing rats. Despite the common embryonic origin of the intestine and stomach, their enzymes showed quite different activity levels and patterns of development, depending on their roles. Most enzyme activities were low during late intrauterine life and after birth, attaining adult levels with the change of diet at weaning. No arginase activity was found in the stomach and no changes were detected in adenylate deaminase in the stomach or intestine throughout the period studied. Alanine transaminase, serine dehydratase and, to some extent, glutamine synthetase levels, significantly higher in late intrauterine life, decreased after birth, suggesting that the foetal stomach has a transient ability to handle amino acids.
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PMID:Activities of amino acid metabolizing enzymes in the stomach and small intestine of developing rats. 286 86

Alanine aminotransferase (AlAT), aspartate aminotransferase (AspAT), adenosine deaminase (ADA) and 5'-nucleotidase (5'-NT) activities were studied in the rat intestine smooth muscles after 24 and 48 hours of fasting. It was found that fasting evoked a significant decrease in ADA and increase in 5'-NT activities in all intestinal segments analysed. A dual effect of fasting was noted for AspAT and AlAT; after first 24h of fasting the activities of both enzymes decreased and increased again when fasting was continued to 48h. We conclude that during fasting an adaptive response occurs in the smooth muscles of intestine and this may be a part of systemic adaptation to fasting.
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PMID:Effect of fasting on some enzymatic activities in the muscle layer of intestine in the rat. 883 8