Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.4.1 (cytosine deaminase)
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Human Gene/Protein
propionyl-CoA carboxylase alpha subunit 14.4
UPRT 13.7
amidohydrolase domain containing 1 12.6
APOBEC3B 12.5
APOBEC2 12.2
HB1 12.0
APOBEC4 11.9
PBL1 11.8
UNG2 11.6
RBM47 11.6
MRGPRD 11.4
PSG5 11.4
A1CF 11.3
Apolipoprotein B mRNA editing enzyme 11.3
TAF5 11.2
APOBEC3H 11.2
SMUG1 10.9
APOBEC3G 10.9
POU6F2 10.9
APOBEC-1 10.8
A3G 10.8
DND1 10.7
RIPK4 10.7
APOBEC3F 10.6
APOBEC3A 10.5
MZF 10.5
POLK 10.5
UNG 10.5
apolipoprotein B mRNA editing enzyme 10.4
PSG1 10.4
dCK 10.3
HOXC4 10.1
ZNF750 10.1
hnRNP A3 10.1
CASZ1 10.0
myeloid zinc finger 10.0
activation-induced deaminase 9.9
L-plastin 9.9
CEACAM3 9.8
MBD4 9.8
Glypican 3 9.8
PiT-1 9.8
APOBEC3C 9.7
UDG 9.7
AICDA 9.7
TDG 9.7
Activation-induced deaminase 9.5
sarcosine dehydrogenase 9.5
SLC20A2 9.5
dihydrouracil dehydrogenase 9.5
UPP 9.5
uridine phosphorylase 9.5
Inosine 5'-monophosphate dehydrogenase 9.4
P67 9.4
ung 9.4
RBL2 9.3
gastrin releasing peptide receptor 9.3
Uridine phosphorylase 9.3
thymidine kinase 9.2
POLQ 9.2
Beta-galactosidase 9.2
FOXN1 9.2
uracil-DNA glycosylase 9.1
melanoma inhibitory activity 9.1
uridine kinase 9.0
RELB 8.9
TCL1A 8.8
DNA polymerase iota 8.8
CEACAM5 8.8
BACH2 8.8
AT-1 8.7
ERG3 8.7
ubiquitin-conjugating enzyme 9 8.7
cytidine deaminase 8.6
PIM2 8.6
excision repair protein 8.5
MYBL2 8.5
deoxycytidine kinase 8.4
activation-induced cytidine deaminase 8.3
DSR 8.3
dihydropyrimidinase 8.3
FBL 8.3
Ribonuclease P 8.3
PEG3 8.2
B-Myb 8.2
TREM-2 8.2
FGR 8.1
REV1 8.1
REV3 8.0
hENT1 8.0
TSG-6 8.0
xeroderma pigmentosum variant 8.0
Thymidine kinase 8.0
IFNGR1 8.0
p202 7.9
IFIT1 7.9
amidophosphoribosyltransferase 7.9
CDC25B 7.9
sarcosine oxidase 7.9
DDX3X 7.8
APOB 7.8
NMU 7.8
BTG2 7.8
ATK 7.8
Dihydropyrimidine dehydrogenase 7.8
Bik 7.8
heat shock transcription factor 1 7.7
interferon-beta 7.7
LATS2 7.6
NFKBIA 7.6
Apolipoprotein B 7.6
THO 7.5
EBF1 7.5
TSA 7.5
C5a anaphylatoxin 7.5
CDH2 7.5
UMP synthase 7.5
L19 7.5
glutamine amidotransferase 7.4
purine nucleoside phosphorylase 7.4
BIP 7.3
ape 7.3
protectin 7.3
KMT2D 7.3
dUTPase 7.3
GCLM 7.3
MVP 7.2
dihydropyrimidine dehydrogenase 7.2
TIM 7.2
A33 7.1
CEACAM1 7.1
OCM 7.1
HTB 7.1
gastrin-releasing peptide receptor 7.1
survival-related 7.1
sodium iodide symporter 7.1
peptide deformylase 7.1
cholesteryl ester hydrolase 7.0
VISA 6.9
SCD 6.9
thymidine phosphorylase 6.9
FOV 6.9
RELA 6.9
Endostatin 6.9
EP300 6.9
NAR 6.9
TAG-1 6.8
DREAM 6.8
LAN 6.8
flt 6.8
SGC 6.8
PDL1 6.8
p48 6.8
colon carcinoma 6.7
histone deacetylase 6 6.7
melanoma-associated antigen 6.7
HSE 6.7
FBXW7 6.7
CIITA 6.7
MIA 6.7
pigment epithelium-derived factor 6.7
WISH 6.6
prostate-specific membrane antigen 6.6
XPG 6.6
death receptor 5 6.6
carboxylesterase 6.6
endostatin 6.5
HIF1 6.5
F10 6.5
CDA 6.5
p107 6.5
TRAF3 6.5
CHEK2 6.5
BAFF 6.5
MTS 6.4
thymidylate synthase 6.4
CYLD 6.4
CMP 6.4
HAD 6.4
Cr2 6.4
MMP7 6.4
XPF 6.4
AMP deaminase 6.3
CTF 6.3
ataxia telangiectasia mutated 6.3
YB-1 6.3
E1B 6.3
B17 6.3
PEA3 6.3
dihydroorotate dehydrogenase 6.3
P27 6.2
GFA 6.2
DAC 6.2
BCL6 6.2
pVHL 6.2
ribonucleotide reductase 6.2
HYP 6.2
MSC 6.2
NIS 6.2
NTR 6.2
CD46 6.2
Ep-CAM 6.1
Bfl-1 6.1
NF-IL6 6.1
somatostatin receptor 6.1
epithelial cell adhesion molecule 6.1
Bcl-6 6.1
EP2 6.1
carcinoembryonic antigen 6.0
PSMA 6.0
telomerase reverse transcriptase 6.0
PAX6 6.0
HIS 6.0
choline kinase 5.9
heterogeneous nuclear ribonucleoprotein 5.9
apolipoprotein B 5.9
TRA 5.9
C-X-C chemokine receptor type 4 5.9
GES 5.9
DICER1 5.9
Carcinoembryonic antigen 5.8
inhibitor 2 5.7
TRAIL-R1 5.7
X-linked inhibitor of apoptosis protein 5.7
cyclin-dependent kinase 4 5.7
Dnmt1 5.7
OGG1 5.7
CCL19 5.7
ERBB2 5.7
tumor-associated antigen 5.7
adenosine deaminase 5.6
E.coli 5.6
CXCR5 5.6
dihydrofolate reductase 5.6
interleukin-18 5.6
RB1 5.6
nerve growth factor receptor 5.6
TNF-related apoptosis-inducing ligand 5.5
SIV 5.5
PDX-1 5.5
CXCL13 5.5
ATAC 5.5
DHFR 5.5
hOGG1 5.5
E2F-1 5.5
TNF-a 5.5
MIP-1beta 5.5
PNP 5.4
phosphorylating 5.4
homeodomain transcription factor 5.4
hTERT 5.4
thymidylate synthetase 5.4
c-src 5.4
chimeric protein 5.3
CCR1 5.3
C21 5.3
CDKN1A 5.3
TRAIL 5.3
p21 protein 5.3
TIC 5.3
FGFR3 5.2
C5a receptor 5.2
tyrosinase 5.2
c-Rel 5.2
uPAR 5.2
FUS 5.2
RNase H 5.1
vascular endothelial growth factor receptor 2 5.1
VEGFR2 5.1
topoisomerase I 5.1
mdr1 5.1
triosephosphate isomerase 5.1
DCC 5.1
CCL 5.1
E. coli) 5.0
interleukin-17 5.0
H2AX 5.0
D10 5.0
DNMT1 5.0
Hua 5.0
53BP1 5.0
mucin 1 5.0
stem cell factor 5.0
apoB-100 4.9
PIK3CA 4.9
PHI 4.9
PC3 4.9
cell surface antigen 4.9
gem 4.9
hsp70 4.9
CD2 4.8
TdT 4.8
DEAD 4.8
CCND1 4.8
AKT1 4.8
TCA 4.7
pyrophosphatase 4.7
survivin 4.7
fibrillin 4.7
scFv 4.7
NTP 4.7
non-catalytic 4.7
CD21 4.7
CD1 4.7
TERT 4.7
mutant p53 4.7
ORF1 4.7
KDR 4.6
BAX 4.6
RNA binding protein 4.6
TRP 4.6
FBS 4.6
CRT 4.6
A20 4.6
K12 4.6
Nestin 4.6
PC-3 4.6
SCF 4.6
integrase 4.6
GBM 4.5
more...
Disease
IgM MGUS 9.5
NHD 9.1
CCV 9.1
Prostate tumor 8.8
refractory cancer 8.3
FBL 8.3
suicide 8.2
gliosarcoma 8.2
retroviral disease 8.1
DHD 8.0
metastatic colon cancer 8.0
DHD 7.9
metastatic ovarian cancer 7.9
OCM 7.9
APOB 7.8
Tumour necrosis 7.6
Cholangiocarcinoma 7.2
CYLD 7.0
Cholangiocarcinoma 7.0
metastatic neuroblastoma 7.0
herpes simplex 7.0
bone cancer 6.9
Adenovirus 6.9
VISA 6.9
SCD 6.8
Vesicular stomatitis 6.7
XPG 6.5
CDA 6.4
glioma 6.4
MTS 6.3
XPF 6.3
inflammatory breast cancer 6.0
ATN 5.9
X-linked agammaglobulinemia 5.9
carcinomatosis 5.8
neck cancer 5.8
recurrent breast cancer 5.8
recurrent cancer 5.8
tumor growth 5.7
anaplastic thyroid cancer 5.7
laryngeal squamous cell carcinoma 5.7
ACD 5.6
CAA 5.4
brain tumor 5.4
DDP 5.3
CNS tumors 5.3
solid tumor 5.3
brain metastases 5.2
glioblastoma 5.2
FUS 5.2
CCL 5.1
Thyroid cancer 5.0
B-cell lymphomas 5.0
CAA 5.0
vaccinia 5.0
cytomegalovirus 5.0
Adenocarcinoma 5.0
malignant mesothelioma 4.9
liver metastases 4.9
colon cancer 4.9
medulloblastoma 4.8
measles 4.8
medullary thyroid carcinoma 4.6
FBS 4.6
lung metastases 4.6
glioblastoma multiforme 4.5
carcinosarcoma 4.4
rhabdomyosarcoma 4.4
pancreatic cancer 4.4
tumor 4.3
amebiasis 4.3
brain cancer 4.3
peripheral vascular disease 4.3
ADH 4.3
macroglobulinemia 4.2
adenocarcinoma 4.2
tumor vasculature 4.2
melanoma 4.2
gammopathy 4.1
minimal residual disease 4.1
human papilloma virus 4.0
human papilloma virus 4.0
laryngeal cancer 4.0
hepatoblastoma 4.0
mitral valve prolapse 3.9
Rous sarcoma 3.8
ovarian cancer 3.8
tic 3.8
Hepatocellular carcinoma 3.7
hepatitis A 3.7
cancer 3.7
infectious mononucleosis 3.7
MCF 3.6
SCID 3.5
Marfan syndrome 3.5
prostate cancer 3.5
Dissociation 3.5
colorectal cancer 3.5
epithelial ovarian cancer 3.5
metastatic breast cancer 3.4
sickle cell disease 3.4
hepatocellular carcinoma 3.4
myeloid leukemia 3.4
erythroleukemia 3.4
choriocarcinoma 3.4
candidiasis 3.4
mouth disease 3.4
Cryptococcus neoformans 3.4
CEM 3.3
sarcoma 3.3
metastases 3.3
varicella 3.3
stomatitis 3.3
Hippel 3.2
lipoma 3.2
breast cancer 3.2
ABL 3.2
PCA 3.2
MRS 3.2
lung carcinoma 3.2
carcinoma 3.2
CCD 3.2
Newcastle disease 3.1
Epstein 3.1
cystic fibrosis 3.1
CCD 3.1
HIV 3.0
osteosarcoma 2.9
liver cancer 2.9
myelosuppression 2.8
tumor angiogenesis 2.8
Burkitt's lymphoma 2.8
ATM 2.7
leukemia 2.7
NOD 2.7
primary tumor 2.7
PDB 2.7
macular degeneration 2.6
mesothelioma 2.6
schwannoma 2.6
diphtheria 2.5
fibrosarcoma 2.5
renal cell carcinoma 2.5
liver cancer 2.5
Infection 2.5
Melanoma 2.5
immunodeficiency 2.4
head and neck cancer 2.4
lung cancer 2.4
anaphylaxis 2.4
tumor progression 2.4
bladder cancer 2.4
herpes 2.3
thyroid cancer 2.3
Kaposi's sarcoma 2.3
Blocking 2.2
neuroblastoma 2.2
virus infection 2.1
plaque 2.0
diabetic nephropathy 2.0
Klebsiella 2.0
malaria 1.9
endometrial cancer 1.9
tumorigenesis 1.9
gastric cancer 1.8
skin cancer 1.8
leishmaniasis 1.7
NAME 1.7
lymphoma 1.6
preeclampsia 1.5
squamous cell carcinoma 1.5
myelodysplastic syndrome 1.5
hypercholesterolemia 1.5
bacterial infection 1.5
Haemophilus 1.5
peritonitis 1.5
pancreatitis 1.4
B-cell lymphoma 1.4
infectious diseases 1.4
SDS 1.3
fungal infection 1.3
acute myeloid leukemia 1.3
multiple myeloma 1.2
chronic myeloid leukemia 1.2
cervical cancer 0.9
coronary artery disease 0.9
glaucoma 0.9
dehydration 0.8
proteinuria 0.8
malnutrition 0.6
liver disease 0.5
myocardial ischemia 0.4
carcinogenesis 0.4
dysplasia 0.4
uterus 0.3
hepatitis C 0.3
hepatitis B 0.2
AIDS 0.1
cold -0.1
heart failure -0.8
West -0.8
atherosclerosis -0.9
Alzheimer's disease -1.4
hypertension -2.0
depression -2.0
Symptom
arthralgia 2.6
starvation 1.8
analgesia 0.6
vomiting 0.4
diarrhea -0.4
anesthesia -1.4
pain -2.6
Drug
5-Fluorouridine 10.9
Gadoteridol 9.4
Hydroxyethylstarch 8.7
Cytidine 8.5
Protamine sulfate 8.4
Atovaquone 8.0
Atovaquone 7.6
G418 6.8
CPT-11 6.1
Ganciclovir 5.8
Bifidobacterium 5.7
-deoxyadenosine 5.4
AraC 5.3
Etoposide 5.2
CCL 5.0
Fluconazole 5.0
Taxol 4.7
ADR 4.4
Fluorescein 4.0
Alanine 3.9
IFN-beta 3.8
MRC 3.6
HCH 3.6
NH3 3.6
Fluorescein 3.5
Spectrum 3.4
IL-2 2.5
lysine 2.5
CSF 2.5
DNase I 2.4
citric acid 2.1
Asn 1.9
IFN-gamma 1.6
Gel 1.5
lactose 1.4
Dermatol -2.6
Enzyme
cytosine deaminase 15.4
uracil phosphoribosyltransferase 13.8
EC 2.4.2.2 13.8
AtzC 12.9
N-methylhydantoin amidohydrolase 12.8
beta-alanine-pyruvate aminotransferase 12.8
imidazolonepropionase 12.6
AtzB 12.2
uridine hydrolase 11.9
N-carbamoylsarcosine amidohydrolase 11.8
adenine deaminase 10.3
atrazine chlorohydrolase 10.3
nucleoside hydrolase 9.9
uridine phosphorylase 9.7
nucleoside phosphotransferase 9.5
uridine kinase 9.3
thymidine kinase 9.2
deoxycytidine deaminase 9.0
EC 2.6.1.16 8.9
cytidine deaminase 8.6
orotate phosphoribosyltransferase 8.6
DSR 8.5
homoserine kinase 8.4
threonine dehydrogenase 8.3
deaminase 8.3
dihydropyrimidinase 8.3
deoxycytidine kinase 8.2
GMP synthetase 8.2
dihydropyrimidine dehydrogenase 8.0
sarcosine oxidase 7.9
carboxypeptidase G2 7.9
triose-phosphate isomerase 7.8
PRPP synthetase 7.5
3C protease 7.4
peptide deformylase 7.4
dihydropyrimidine dehydrogenase 7.4
alanine dehydrogenase 7.3
purine nucleoside phosphorylase 7.2
dihydroorotase 7.2
TSA 7.1
orotidine-5'-phosphate decarboxylase 7.0
thymidine phosphorylase 7.0
dUTPase 6.7
aspartate transcarbamylase 6.6
choline kinase 6.6
dihydroorotate dehydrogenase 6.4
dihydroorotate dehydrogenase 6.4
thymidylate synthase 6.4
ribonucleotide reductase 6.2
ribonucleotide reductase 6.1
AMP deaminase 5.9
carboxylesterase 5.8
adenosine deaminase 5.6
adenosine deaminase 5.6
prostate-specific membrane antigen 5.6
dihydrofolate reductase 5.5
beta-galactosidase 5.1
RNase P 5.0
RNase H 5.0
firefly luciferase 4.9
chalcone synthase 4.8
tyrosinase 4.8
luciferase 4.7
cathepsin G 4.6
phosphorylase 4.5
TdT 4.5
phytase 4.4
phytase 4.4
HIV-1 protease 4.3
ADH 4.3
prostate-specific antigen 4.2
sialidase 4.0
beta-glucuronidase 3.5
P-glycoprotein 3.3
IKK 3.1
DNA methyltransferase 3.1
ceruloplasmin 3.1
hexokinase 3.0
DNA polymerase 2.9
endonuclease 2.8
ribonuclease 2.7
ribonuclease 2.7
urease 2.6
NOS 2.5
urease 2.5
reverse transcriptase 2.4
ERK 2.4
RNase 2.4
RNA polymerase 2.3
RNase 2.2
ACE 2.2
topoisomerase 2.2
alcohol dehydrogenase 2.2
transcriptase 2.2
topoisomerase 2.1
ACS 1.9
beta-lactamase 1.7
PARP 1.6
neuraminidase 1.6
peroxidase 1.4
protein kinase C 1.4
caspase-3 1.3
focal adhesion kinase 1.0
alanine aminotransferase 0.7
lactate dehydrogenase 0.5
protein kinase 0.1
alkaline phosphatase -0.2
catalase -0.4
mitogen-activated protein kinase -1.2
Compound
5-FC 12.9
Isocytosine 12.1
N-formimino-l-glutamate 12.1
imidazolone propionate 11.9
FUMP 11.6
FUR 11.0
Ribose, 10.2
isoguanine 9.3
NHD 9.3
Acetyl phosphate 9.2
5-Methylcytosine 8.8
UPP 8.8
Uracil 8.7
Deoxycytidine 8.6
dUMP 8.4
Cyt 8.4
NCD 8.3
C 6 8.1
Cyd 8.0
UMP 7.8
DOPE 7.4
BIP 7.3
Diol 7.3
ribose-5-phosphate 6.7
CDA 6.5
CMP 6.5
5-FU 6.4
CMP 6.4
MNU 6.3
MTS 6.3
B17 6.3
SN-38 6.3
DAC 6.2
pyrimidine 6.2
pyrimidine 6.2
dCMP 6.1
CPT-11 6.1
2-(dimethylamino)ethyl 6.1
2-(dimethylamino)ethyl 6.0
MNU 6.0
MBT 6.0
Guo 6.0
RELA 5.8
pentaerythritol 5.8
MIA 5.8
Temozolomide 5.7
HIS 5.7
TTP 5.5
uridine 5.4
CAA 5.4
TIC 5.3
DFS 5.0
Thymidine 4.9
dGTP 4.9
PEI 4.9
PEI 4.9
Histidine 4.9
UDP-galactose 4.9
Adenine 4.8
Amide 4.8
myristic acid 4.8
Ara-C 4.8
MTT 4.6
Flux 4.6
MDA 4.6
CCC 4.5
CCC 4.5
myristic acid 4.5
dUTP 4.5
PPi 4.4
beta-alanine 4.4
Ara-C 4.4
CdCl2 4.3
PNP 4.3
DCC 4.2
UTP 4.2
HEPES 4.1
benzophenone 4.0
Alanine 4.0
Paclitaxel 3.9
perchloric acid 3.9
2-propanol 3.8
TCA 3.8
2-propanol 3.8
CTP 3.8
COS 3.8
diacetate 3.8
VP-16 3.7
formamide 3.7
Neo 3.7
succinic acid 3.6
PDB 3.5
PMA 3.4
alloxan 3.4
adenosylmethionine 3.3
CCl4 3.1
DNA 3.1
hydroxide 3.1
MIC 3.0
acetyl-CoA 3.0
ammonia 2.9
zinc 2.8
ubiquinone 2.8
His 2.8
PMA 2.8
ADR 2.8
Glutamate 2.7
Adenosine 2.6
ammonium 2.6
acetic acid 2.6
2-oxoglutarate 2.5
TNM 2.4
tryptophan 2.4
alcohol dehydrogenase 2.3
bromide 2.3
fluorine 2.3
PGE 2.3
CAT 2.2
CAT 2.2
cobalt 2.2
Estrogen 2.2
isopropanol 2.2
CAT 2.1
Panam 2.1
PEG 2.1
Carbon 2.1
lysine 2.1
THP 2.0
Estrogen 2.0
THP 2.0
ADP 2.0
N-acetylcysteine 2.0
salicylic acid 1.9
ACS 1.9
ACS 1.9
NADP 1.9
PEG 1.9
Asp 1.9
NH2 1.9
alanine 1.9
asparagine 1.8
nitrogen 1.8
ADP 1.8
ADP 1.7
aspartic acid 1.7
glutamine 1.7
GlcNAc 1.7
arginine 1.6
Mg2+ 1.6
manganese 1.3
SDS 1.2
ATP 1.2
pyrene 1.1
NAD 1.1
leucine 1.1
TOF 1.1
sulfate 0.9
NAD 0.7
DSM 0.7
GTP 0.5
titanium 0.5
H2O2 0.5
TNF 0.5
nickel 0.5
proline 0.4
serine 0.4
Pac 0.3
cadmium 0.3
tryptophan 0.3
tryptophan 0.3
tryptophan 0.2
galactose 0.2
cysteine 0.2
salt 0.2
acetate 0.1
glycerol 0.1
hydrogen 0.1
water -0.0
phosphate -0.1
CO2 -0.1
iron -0.1
Dec -0.1
tyrosine -0.2
iodine -0.2
glucose -0.2
methionine -0.5
creatinine -0.5
silver -0.5
oxygen -0.5
glutamate -0.8
BMC -1.1
copper -1.1
Clin -1.3
sodium -1.7