Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.52 (PNGase F)
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Human Gene/Protein
chromosome 2 open reading frame 7 14.3
N-glycanase 13.7
PNG1 13.6
tyrosinase precursor 13.3
Retinal pigment epithelium-specific protein 13.3
hPAP21 13.3
C19orf24 13.3
SID1 transmembrane family, member 2 12.8
NGLY1 12.6
LPHA 12.3
B3GNT8 12.3
lysozyme precursor 12.3
Acid carboxypeptidase 11.9
hCLCA4 11.8
Na+/H+ exchanger isoform NHE-3 11.8
HUT11 11.4
SLC4A8 11.2
PGDS protein 11.2
Endo-beta-N-acetylglucosaminidase 11.1
glucosaminyl 11.0
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Disease
Carbohydrate-deficient glycoprotein syndrome 9.8
Feline Leukemia 9.4
FAIDS 9.4
X-linked ocular albinism 8.7
JMS 7.7
fucosidosis 7.6
CLN5 7.4
EL2 7.4
mixed gliomas 7.4
toxic nodular goiter 7.1
Aspartylglucosaminuria 6.9
LQT2 6.8
hereditary fructose intolerance 6.7
pineoblastoma 6.6
Pfeiffer 6.6
STL 6.5
diffuse goiter 6.3
SDS 6.3
sialidosis 6.3
HMS 6.2
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Symptom
HSA 2.8
cachexia 1.9
Ill 0.9
thinning 0.9
starvation 0.7
collapse 0.5
seizures -0.4
diarrhea -1.5
Drug
1-Deoxynojirimycin 8.7
Batroxobin 8.4
Ceftibuten 8.0
Swainsonine 8.0
Ancrod 7.7
Asn 7.6
Estracyt 7.5
Estracyt 7.3
GNA 7.3
Pronase 7.0
Darbepoetin alfa 7.0
Bromelain 6.9
NAG 6.4
Epoetin 6.3
Papain 6.2
NovoSeven 6.1
Monensin 6.0
Enrofloxacin 5.9
Flunitrazepam 5.9
beta-Galactosidase 5.6
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Enzyme
PNGase F 14.3
okinaxobin II 13.3
endomannosidase 10.9
aminopeptidase W 10.9
Rmd 10.5
endo-beta-galactosidase 10.5
endoglycosidase H 10.4
endo-beta-galactosidase 10.2
endo-alpha-N-acetylgalactosaminidase 10.2
deuterolysin 9.8
mannosidase I 9.5
N-acetylglucosaminyltransferase II 9.4
glycoprotease 9.4
stem bromelain 9.2
GPI-PLD 9.1
mannosylphosphoryldolichol synthase 9.1
endo-N 8.8
N-acetylglucosaminyltransferase I 8.7
chymotrypsin C 8.7
beta-1,4-galactosyltransferase 8.6
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Compound
N-Benzoyl-L-tyrosine ethyl ester 13.3
N-Acetyl-L-tyrosine 11.3
Neu4,5Ac2 10.9
2-AB 10.7
Ac-Tyr-OEt 10.5
2-aminobenzamide 10.5
2-AA 10.1
2-aminobenzoic acid 9.9
2-aminobenzoic acid 9.9
LNFP I 9.8
trifluoromethanesulfonic acid 9.8
trifluoromethanesulfonic acid 9.7
Sedoheptulose 9.7
palmitamide 9.6
Phenamil 9.2
Castanospermine 9.1
Tunicamycin 8.8
N-Hydroxysuccinimide 8.7
Zwittergent 3-14 8.4
asparagine 8.3
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