Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.52 (PNGase F)
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Human Gene/Protein
chromosome 2 open reading frame 7 14.3
N-glycanase 13.7
PNG1 13.6
Retinal pigment epithelium-specific protein 13.3
tyrosinase precursor 13.3
C19orf24 13.3
hPAP21 13.3
SID1 transmembrane family, member 2 12.8
NGLY1 12.6
LPHA 12.3
B3GNT8 12.3
lysozyme precursor 12.3
Acid carboxypeptidase 11.9
Na+/H+ exchanger isoform NHE-3 11.8
hCLCA4 11.8
HUT11 11.4
SLC4A8 11.2
PGDS protein 11.2
Endo-beta-N-acetylglucosaminidase 11.1
glucosaminyl 11.0
SAKS1 10.9
SDS protein 10.9
B4GALNT3 10.8
FR-beta 10.8
Hyal-3 10.6
PAP-2a 10.6
GLUT11 10.6
neighbor of BRCA1 gene 1 10.6
Fbs1 10.6
PUB 10.6
Maltase-glucoamylase 10.5
B4GALNT2 10.5
MANB 10.4
B4-2 10.3
NXN 10.3
Man9-mannosidase 10.3
GP55 10.3
endo-beta-N-acetylglucosaminidase 10.2
LW blood group 10.2
CSS3 10.1
skin tryptase 10.1
ERIC-1 10.0
basic proline-rich protein 10.0
B3GNT2 9.9
SPC1 9.9
sodium-dependent organic anion transporter 9.9
SLC4A10 9.8
H3P 9.8
RhD protein 9.8
DDI1 9.8
Glucosidase I 9.7
beta4Gal-T1 9.7
MGAT3 9.6
MGAT5 9.6
O-sialoglycoprotein endopeptidase 9.6
COL8A2 9.6
alpha 1,2-mannosidase 9.5
LacCer synthase 9.5
hSBP 9.5
EC-SOD 9.5
telencephalin 9.5
osteoinductive factor 9.4
SVEP1 9.4
ALG2 9.4
ST6GAL1 9.3
Butyrophilin 9.3
PMP22 protein 9.3
sodium-dependent vitamin C transporter 2 9.3
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9.3
BST-1 9.2
CD9P-1 9.2
B transferase 9.2
DM9 9.2
Coagulation factor V 9.2
LRG 9.2
cyclophilin C 9.2
N-acetylglucosaminyltransferase II 9.2
glycosylasparaginase 9.1
TCF11 9.1
KLKB1 9.1
STF-1 9.1
PNG 9.1
Rab-interacting lysosomal protein 9.1
p38b 9.1
cystatin M 9.1
MOv18 9.1
beta nerve growth factor 9.1
SPF45 9.1
adhesion molecule on glia 9.1
DPPY 9.1
ST8SIA4 9.0
beta-1,4-galactosyltransferase 9.0
Duffy blood group antigen 9.0
alpha1,2-mannosidase 9.0
Opioid-binding cell adhesion molecule 8.9
NCBE 8.9
pla1 8.9
ST8Sia II 8.9
CLCA2 8.8
CNT3 8.8
LPP3 8.8
SF21 8.8
s-laminin 8.8
ICAM-5 8.8
lamp-2 8.8
N-acetylglucosaminyltransferase I 8.7
hSVCT1 8.7
aspartylglucosaminidase 8.7
EPO protein 8.7
CRF-BP 8.7
TEX101 8.6
Kidd blood group 8.6
MGAT1 8.6
lysosomal sialidase 8.6
alpha-mannosidase 8.6
alpha 2,3-sialyltransferase 8.6
SLC14A1 8.6
AMFR 8.5
58kDa 8.5
LIP2 8.5
PNK 8.5
GlyCAM-1 8.5
Cysteine-rich intestinal protein 8.4
FcRIII 8.4
hCNT3 8.4
Fibromodulin 8.4
DPP10 8.4
SLC4A7 8.4
STT3B 8.4
A transferase 8.4
vitamin K-dependent protein S 8.4
complement component C9 8.4
GN2 8.4
NaSi-1 8.3
CRP protein 8.3
Extracellular superoxide dismutase 8.3
plasma protein C 8.3
D-X 8.3
sperm receptor 8.3
PAPC 8.3
EDEM1 8.3
Nicastrin 8.3
natriuretic peptide receptor B 8.2
FUT6 8.2
Fatty acid translocase 8.2
CD164 8.2
pancreatic lipase-related protein 2 8.2
Biotinidase 8.2
Thyroid peroxidase 8.2
SAT-1 8.2
alpha-L-fucosidase 8.1
Neuraminidase 8.1
gp180 8.1
RILP 8.1
NHE4 8.1
sodium channel alpha-subunit 8.1
CHI3 8.1
ENDO 8.1
N-acetylgalactosaminyltransferase 8.1
lysosomal alpha-glucosidase 8.1
more...
Disease
Carbohydrate-deficient glycoprotein syndrome 9.8
Feline Leukemia 9.4
FAIDS 9.4
X-linked ocular albinism 8.7
JMS 7.7
fucosidosis 7.6
CLN5 7.4
EL2 7.4
mixed gliomas 7.4
toxic nodular goiter 7.1
Aspartylglucosaminuria 6.9
LQT2 6.8
hereditary fructose intolerance 6.7
pineoblastoma 6.6
Pfeiffer 6.6
STL 6.5
diffuse goiter 6.3
SDS 6.3
sialidosis 6.3
HMS 6.2
East Coast fever 6.1
metastatic osteosarcoma 5.9
FDC 5.9
corneal dystrophy 5.9
hyperviscosity syndrome 5.8
monocytic leukemia 5.8
mannosidosis 5.8
Papilloma 5.6
gangliosidosis 5.6
uterine sarcoma 5.5
AAA 5.4
neuronal ceroid lipofuscinosis 5.3
Classical swine fever 5.3
congenital disorder 5.2
Ovary 5.2
NMS 5.1
Farber 5.0
MPS I 5.0
LCA 5.0
Hurler 5.0
Angiostrongylus cantonensis 4.9
Gerstmann 4.9
Tic 4.9
RMD 4.9
Schistosoma japonicum 4.8
ADCC 4.8
lysosomal storage disease 4.8
IPS 4.8
autoimmune thyroid disease 4.8
prostatic disease 4.7
galactosemia 4.7
CLN3 4.7
CEM 4.6
MSA 4.6
avian sarcoma 4.6
NS2 4.6
brain disorder 4.6
hyperosmolality 4.5
NMS 4.5
MEC 4.5
cervical adenocarcinoma 4.5
Ovary 4.5
HPC 4.5
Fraser 4.4
renal tubular acidosis 4.4
HES 4.3
PHA 4.3
Wiskott-Aldrich syndrome 4.2
HOS 4.2
Moore 4.2
epididymis 4.1
bovine leukemia 4.1
long QT syndrome 4.1
primitive neuroectodermal tumor 4.0
papilloma 4.0
choriocarcinoma 3.9
abdominal aortic aneurysm 3.9
Rous sarcoma 3.8
vaccinia 3.8
primitive neuroectodermal tumor 3.7
paroxysmal nocturnal hemoglobinuria 3.7
tendinitis 3.7
Tay-Sachs disease 3.7
diabetic cardiomyopathy 3.7
lymphosarcoma 3.7
herpes zoster 3.6
endometrial adenocarcinoma 3.6
HDL3 3.6
embryonal carcinoma 3.6
NS3 3.6
mastocytoma 3.6
autoimmune hemolytic anemia 3.6
FBS 3.5
polycythemia 3.5
PAM 3.5
AGA 3.5
insulinoma 3.5
mitochondrial disease 3.5
PNS 3.5
CIE 3.4
neurofibroma 3.4
erythroleukemia 3.4
EDA 3.3
Chlamydia 3.3
Marek's disease 3.3
AMD 3.3
dysentery 3.3
Hashimoto's thyroiditis 3.2
precocious puberty 3.2
macroglobulinemia 3.2
THC 3.2
paracoccidioidomycosis 3.2
Dukes 3.1
alcoholic cirrhosis 3.1
Newcastle disease 3.1
pharyngitis 3.1
Wilson's disease 3.1
HSP 3.1
T-cell acute lymphoblastic leukemia 3.0
neuroblastoma 3.0
HGF 3.0
malignant fibrous histiocytoma 3.0
Schmidt 3.0
Placenta 2.9
PSA 2.9
hepatoblastoma 2.9
valvular heart disease 2.9
epithelial ovarian cancer 2.9
xeroderma pigmentosum 2.8
stomatitis 2.8
multiple myeloma 2.8
Blocking 2.8
membranous nephropathy 2.8
lymphocytic choriomeningitis 2.7
tic 2.7
CAP 2.7
hemolytic uremic syndrome 2.6
worms 2.6
seminal vesicles 2.6
immunodeficiency 2.6
polyarthritis 2.6
Wright 2.5
Schistosoma mansoni 2.5
chronic pancreatitis 2.5
hepatocellular carcinoma 2.5
scrapie 2.5
SARS 2.4
lymphoblastic leukemia 2.4
acute promyelocytic leukemia 2.4
myeloid leukemia 2.4
avian influenza 2.4
developmental delay 2.4
food allergy 2.3
anthrax 2.3
PML 2.3
Haemophilia 2.3
ATM 2.3
schistosomiasis 2.2
movement disorder 2.2
genetic disorder 2.2
more...
Symptom
HSA 2.8
cachexia 1.9
Ill 0.9
thinning 0.9
starvation 0.7
collapse 0.5
seizures -0.4
diarrhea -1.5
Drug
1-Deoxynojirimycin 8.7
Batroxobin 8.4
Ceftibuten 8.0
Swainsonine 8.0
Ancrod 7.7
Asn 7.6
Estracyt 7.5
Estracyt 7.3
GNA 7.3
Pronase 7.0
Darbepoetin alfa 7.0
Bromelain 6.9
NAG 6.4
Epoetin 6.3
Papain 6.2
NovoSeven 6.1
Monensin 6.0
Enrofloxacin 5.9
Flunitrazepam 5.9
beta-Galactosidase 5.6
MEA 5.6
Gel 5.5
Hyaluronidase 5.5
Maltose 5.5
Hyaluronidase 5.4
Thyroglobulin 5.4
Galactose 5.3
Iloprost 5.3
ABC 5.2
TES 5.2
Urokinase 5.1
Campath 4.8
Campath 4.8
BoNT/A 4.6
DFP 4.5
Cetuximab 4.4
ADR 4.3
Infliximab 4.2
Infliximab 4.2
Herceptin 4.2
RFP 4.1
DPA 4.0
CTA 3.9
Gelatin 3.6
Bevacizumab 3.6
Glucagon 3.5
uPA 3.3
G418 3.2
ETA 2.9
Rituximab 2.9
CaCl2 2.7
CaCl2 2.7
CaCl2 2.7
lactose 2.6
Retinoic acid 2.6
MRC 2.6
THF 2.4
DNase I 2.3
Leaf 2.3
Angiotensin II 2.0
CAM 1.8
Bifidobacterium 1.8
CSF 1.8
NH3 1.6
IL-2 1.5
EE2 1.4
lysine 1.3
ENT 1.3
IFN-gamma 0.5
MAP 0.4
NADH -0.1
Dermatol -2.1
Enzyme
PNGase F 14.3
okinaxobin II 13.3
endomannosidase 10.9
aminopeptidase W 10.9
Rmd 10.5
endo-beta-galactosidase 10.5
endoglycosidase H 10.4
endo-beta-galactosidase 10.2
endo-alpha-N-acetylgalactosaminidase 10.2
deuterolysin 9.8
mannosidase I 9.5
N-acetylglucosaminyltransferase II 9.4
glycoprotease 9.4
stem bromelain 9.2
GPI-PLD 9.1
mannosylphosphoryldolichol synthase 9.1
endo-N 8.8
N-acetylglucosaminyltransferase I 8.7
chymotrypsin C 8.7
beta-1,4-galactosyltransferase 8.6
aspartylglucosaminidase 8.6
GalT 8.5
alpha-mannosidase 8.5
chondroitinase B 8.4
alpha-L-fucosidase 8.4
alpha-L-fucosidase 8.2
galactosyltransferase I 8.2
alpha-L-fucosidase 8.1
leishmanolysin 8.1
carboxyl proteinase 8.1
endoproteinase Asp-N 8.1
mannosidase II 8.1
alpha-N-acetylgalactosaminidase 8.0
GPI-specific phospholipase C 8.0
neuraminidase 7.8
polypeptide N-acetylgalactosaminyltransferase 7.8
glucosidase II 7.8
sialidase 7.8
endoproteinase Glu-C 7.6
ancrod 7.5
alpha-N-acetylglucosaminidase 7.5
deaminase 7.4
chondroitinase 7.3
N-acetylgalactosaminidase 7.3
galactanase 7.2
chondroitinase 7.2
H,K-ATPase 7.1
lichenase 7.1
lactase-phlorizin hydrolase 7.0
N-acetylglucosaminyltransferase V 7.0
pyroglutamate aminopeptidase 7.0
N-acetylglucosaminyltransferase 7.0
chondroitin ABC lyase 6.9
alpha-L-iduronidase 6.8
cathepsin C 6.7
lactase-phlorizin hydrolase 6.7
sialyltransferase 6.6
sialyltransferase 6.6
sialyltransferase 6.6
lysyl endopeptidase 6.4
alcohol oxidase 6.4
ribonuclease 6.4
ribonuclease 6.4
galactose oxidase 6.3
conjugase 6.2
arylsulfatase A 6.1
chondroitinase AC 6.1
heparinase 6.0
ceramidase 6.0
bromelain 5.9
ficin 5.9
phosphomannose isomerase 5.9
hyaluronidase 5.8
legumain 5.7
biotinidase 5.7
carboxypeptidase E 5.7
lecithin:cholesterol acyltransferase 5.7
tissue kallikrein 5.6
trypsin 5.6
carboxypeptidase Y 5.6
CPN 5.6
sucrase-isomaltase 5.6
hexosaminidase 5.6
pepsin 5.5
chymosin 5.5
caspase-6 5.5
RNase 5.4
RNase 5.4
caspase-6 5.4
beta-glucosidase 5.3
meprin 5.2
dipeptidyl peptidase IV 5.2
PI-PLC 5.2
kallikrein 5.1
carboxypeptidase B 5.1
branching enzyme 5.1
furin 5.0
cathepsin L 5.0
papain 5.0
polynucleotide kinase 5.0
enterokinase 4.9
proteinase K 4.9
beta-1,3-glucanase 4.9
beta-1,3-glucanase 4.9
transglutaminase 4.9
proteasome 4.9
chymotrypsin 4.8
insulin-degrading enzyme 4.8
rhodanese 4.8
prolyl endopeptidase 4.7
TACE 4.7
ubiquitin-protein ligase 4.7
beta-galactosidase 4.7
alpha-galactosidase 4.6
subtilisin 4.6
beta-secretase 4.6
lignin peroxidase 4.5
tryptase 4.5
interstitial collagenase 4.5
thermolysin 4.5
mannanase 4.5
invertase 4.4
neutrophil elastase 4.4
ADP-ribosyltransferase 4.4
phospholipase C 4.3
thyroid peroxidase 4.3
ADP-ribosyltransferase 4.3
sulfatase 4.3
ricin 4.3
matrix metalloproteinase 9 4.2
tissue plasminogen activator 4.2
sucrase 4.1
pectinase 4.1
cellobiohydrolase 4.0
asparaginase 4.0
cathepsin D 3.9
cathepsin B 3.9
dopamine beta-hydroxylase 3.9
beta-glucosidase 3.9
chitinase 3.9
thrombin 3.8
hyaluronidase 3.8
alpha-amylase 3.6
urokinase-type plasminogen activator 3.5
CD13 3.5
cathepsin G 3.5
tyrosinase 3.5
enolase 3.5
PAM 3.5
botulinum neurotoxin 3.5
CD10 3.4
APC 3.4
phospholipase A2 3.4
glucoamylase 3.3
lactase 3.3
acid phosphatase 3.3
chaperonin 3.3
glyceraldehyde-3-phosphate dehydrogenase 3.3
glyceraldehyde-3-phosphate dehydrogenase 3.2
P-glycoprotein 3.2
more...
Compound
N-Benzoyl-L-tyrosine ethyl ester 13.3
N-Acetyl-L-tyrosine 11.3
Neu4,5Ac2 10.9
2-AB 10.7
Ac-Tyr-OEt 10.5
2-aminobenzamide 10.5
2-AA 10.1
2-aminobenzoic acid 9.9
2-aminobenzoic acid 9.9
LNFP I 9.8
trifluoromethanesulfonic acid 9.8
trifluoromethanesulfonic acid 9.7
Sedoheptulose 9.7
palmitamide 9.6
Phenamil 9.2
Castanospermine 9.1
Tunicamycin 8.8
N-Hydroxysuccinimide 8.7
Zwittergent 3-14 8.4
asparagine 8.3
Benzamidine 8.2
GlcNAc 8.1
Ceftibuten 8.1
3-aminobenzoic acid 7.9
KDN 7.9
N-Acetylglucosamine 7.8
Estramustine 7.8
GDP-L-fucose 7.7
Swainsonine 7.7
GalNAc 7.6
Stains-all 7.6
iduronate 7.5
Rabeprazole 7.5
2-ethylhexanoic acid 7.4
Neu5Ac 7.4
Remazol Brilliant Blue R 7.3
TRU 7.3
keratan sulfate 7.2
Saxitoxin 7.2
DDM 7.2
Mannose 7.1
BPL 7.0
Estracyt 7.0
Estracyt 7.0
3'-AMP 6.9
Fucose 6.8
Lewis X 6.7
UDP-galactose 6.6
Brefeldin A 6.6
Brefeldin A 6.6
Sialic acid 6.5
nitrous acid 6.5
CH3-THF 6.5
BBM 6.5
SOA 6.4
galactose 6.4
DMM 6.3
SDS 6.3
PAG 6.3
Dermatan sulfate 6.2
Glu-Glu 6.2
TOF 6.2
DDM 6.2
HMS 6.2
phenyl acetate 6.1
N-acetyl-D-glucosamine 6.1
Monensin 6.1
Thiabendazole 6.1
Chondroitin 6.0
Cystine 5.9
CMP 5.9
Rhodopsin 5.9
PNA 5.9
TBT 5.8
CMP 5.7
propionamide 5.7
propionamide 5.7
TES 5.7
NH4OH 5.6
Cystine 5.6
APS 5.6
5-formyltetrahydrofolate 5.5
MEA 5.5
hexose 5.5
E-64 5.5
MNA 5.5
Maltose 5.5
MNA 5.5
Factor X 5.4
AAA 5.4
D-glucosamine 5.4
NTA 5.4
beta-D-galactoside 5.4
POPC 5.4
ASN 5.3
Galactose 5.3
5-methylisoxazole 5.2
2,5-dihydroxybenzoic acid 5.2
11-cis-retinal 5.2
2,5-dihydroxybenzoic acid 5.2
T13 5.2
UDP-GlcNAc 5.1
MEGA 5.1
Cytochalasin D 5.1
Heparan sulfate 5.1
UDP 5.1
CBS 5.1
hydrazine 5.1
2,5-dihydroxybenzoic acid 5.0
phosphoserine 5.0
Gb3 5.0
DTT 5.0
Phorbol 12-myristate 13-acetate 5.0
Brilliant Blue 4.9
COS 4.9
DTT 4.9
BOP 4.9
PMSF 4.9
GD3 4.8
mesityl 4.8
Asp 4.8
Triton X-100 4.8
threonine 4.8
PAM 4.8
PAM 4.8
IDA 4.7
Lea 4.7
aspartic acid 4.7
aspartic acid 4.7
TACE 4.7
Trypsin 4.7
2-mercaptoethanol 4.7
Ether 4.6
1H-imidazole 4.6
Polypeptide 4.6
Ether 4.6
hexose 4.6
hexose 4.6
hexose 4.6
SITS 4.6
HPC 4.6
AAT 4.6
DEAE 4.6
HPC 4.6
aspartic acid 4.5
Phosphatidylinositol 4.5
sulfate 4.5
xylose 4.5
Pectin 4.5
aspartic acid 4.4
Methionine 4.4
Hypo 4.4
carbonic acid 4.3
phenylboronic acid 4.3
octanoic acid 4.3
DPA 4.3
GM3 4.3
HBr 4.3
DPA 4.2
MTX 4.2
more...