Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.5 (urease)
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Human Gene/Protein
Allantoicase 10.1
OR51B5 10.1
ASB1 10.0
Kangai 1 9.8
OHCU decarboxylase 9.8
TJ6 9.6
Alkaline phosphomonoesterase 9.5
aquarius 9.5
EFG2 9.3
HAO2 9.1
CD300E 9.1
ASB3 8.9
integral membrane protein 2A 8.8
KDEL receptor 1 8.8
CP11 8.8
PPHA 8.8
alkaline phosphomonoesterase 8.7
HLA-DRB1*0402 8.5
arylsulfatase 8.4
SAR1A 8.3
L-lactic dehydrogenase 8.2
beta-ureidopropionase 8.1
AK6 8.1
KAI1 protein 8.1
arylsulphatase 8.0
SLC14A1 8.0
AD 2 7.9
VPH1 7.9
ASB2 7.9
p62dok 7.8
beta-alanine synthase 7.7
CL-6 7.7
N-acetylglucosamine-6-phosphate deacetylase 7.7
SS1 7.7
UDP-N-acetylglucosamine pyrophosphorylase 7.5
ITSN 7.5
IPK1 7.4
MND1 7.4
transcription regulator protein 7.3
histidase 7.3
K72 7.3
L-glutaminase 7.3
ALC 7.2
LIME 7.2
ASP1 7.1
acetaldehyde dehydrogenase 2 7.1
CHOD 7.1
MINCLE 7.1
SALL2 7.1
N-acetylglutamate synthetase 7.1
TOPORS 7.1
glucosidase 7.0
SEC6 7.0
D123 7.0
K26 6.9
AK4 6.9
ITSN1 6.9
DCD 6.9
PDE7B 6.9
HG3 6.9
EB-1 6.9
CFBP 6.9
lipoxygenase-3 6.8
phosphomonoesterase 6.8
melanoregulin 6.8
ORF-3 6.7
TIFA 6.7
Napsin-A 6.6
Dermcidin 6.6
CO4 6.6
rd12 6.5
Hb1 6.5
PKR1 6.5
BS4 6.5
AOA 6.4
MAP3K5 6.4
thiosulfate sulfurtransferase 6.4
gastric mucin 6.3
dihydropyrimidinase 6.3
TDH 6.3
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Disease
Helicobacter-associated disease 11.1
Cervical Carcinoma 10.1
Chronic superficial gastritis 9.8
Chronic antral gastritis 9.8
Superficial gastritis 9.3
Gastric infection 9.3
tyrosinuria 9.3
Vestibular vertigo 9.3
urethrolithiasis 9.1
H pylori infection 9.0
Disseminated trichosporonosis 8.9
Proteus mirabilis infection 8.8
alcoholic gastritis 8.6
Helicobacter pylori infection 8.5
gastric mucosal atrophy 8.4
Chronic gastritis 8.4
Erosive esophagitis 8.2
gastritis 8.1
galactosuria 7.8
Brunner's gland hyperplasia 7.7
antritis 7.7
Ureaplasma infection 7.6
GUD 7.5
duodenitis 7.5
Upper gastrointestinal symptoms 7.4
Pulmonary coccidioidomycosis 7.4
acute gastritis 7.4
peptic ulcer 7.3
dyspepsia 7.3
bartholinitis 7.2
gastroduodenitis 7.2
Helicobacter pylori gastritis 7.2
Gastric lymphoma 7.2
orotic aciduria 7.2
duodenal ulcer 7.2
Proteus 7.2
TBCD 7.1
gastric ulcer 6.7
Digestive Diseases 6.6
OCM 6.6
Portal hypertensive gastropathy 6.6
TDD 6.5
atrophic gastritis 6.4
AOA 6.4
Supragingival plaque 6.4
tinea corporis 6.4
Disseminated cryptococcosis 6.4
chronic laryngitis 6.3
Pulmonary sarcoidosis 6.2
Diaper dermatitis 6.2
Stomach 6.2
mucosa-associated lymphoid tissue 6.2
Biotin deficiency 6.1
gastric neoplasm 6.1
onychogryphosis 6.1
pyelitis 6.0
urolithiasis 6.0
Bacterial sepsis 5.9
AA2 5.9
Stomach 5.9
Stomach 5.9
Stomach 5.9
hyperornithinemia 5.9
pH increased 5.9
rat-bite fever 5.9
cystinuria 5.8
infectious meningitis 5.8
Other variants 5.8
nail infection 5.8
functional diarrhea 5.7
propionic acidemia 5.7
HSAN 5.7
Gastric outlet obstruction 5.6
CTPA 5.6
hyperprolinemia 5.5
Phaeohyphomycosis 5.5
AGS 5.5
mesenteric lymphadenitis 5.4
chronic urinary tract infection 5.4
HND 5.4
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Symptom
Cloudy urine 10.1
Gastrointestinal distress 8.5
skin impairment 7.6
epigastric distress 6.5
Blanching 5.4
acid regurgitation 4.7
belching 4.4
acidity 4.1
epigastric pain 4.0
consciousness disturbance 4.0
forgetfulness 3.7
eds 3.6
heartburn 3.4
stomach pain 3.1
twitching 3.1
Gastrointestinal symptoms 2.9
pleuritic chest pain 2.9
neck stiffness 2.9
abdominal pain 2.5
intestinal bleeding 2.4
rigors 2.4
general problem 2.3
microbial colonization 2.0
Hudson 2.0
flank pain 2.0
agitation 2.0
productive cough 2.0
hypoproteinemia 2.0
lethargy 1.9
hypertonia 1.8
tachypnea 1.8
diarrhea 1.7
Wind 1.7
nasal discharge 1.7
starvation 1.6
vomiting 1.5
bloating 1.4
oliguria 1.2
nausea 1.2
acute abdominal pain 1.1
fever of unknown origin 1.1
erythema 1.0
polydipsia 1.0
dysuria 0.8
sore throat 0.7
shoulder pain 0.7
hoarseness 0.6
HSA 0.6
polyuria 0.5
tremor 0.5
colic 0.5
flushing 0.5
discomfort 0.5
anorexia 0.3
discomfort 0.3
vertigo 0.3
collapse 0.3
acute pain 0.1
regurgitation 0.1
chills 0.0
paresthesia -0.2
Ill -0.3
thinning -0.4
hepatomegaly -0.4
hypotonia -0.4
back pain -0.5
tinnitus -0.6
cough -0.9
weakness -1.1
dizziness -1.1
splenomegaly -1.2
constipation -1.2
headache -1.4
sleepiness -1.5
dyspnea -1.7
ataxia -1.9
pain -2.0
overweight -2.6
seizures -3.2
fatigue -3.6
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Drug
Calcibind 12.1
Lithostat 12.1
Ammonia water 10.1
Troxipide 9.5
Oyster shell 8.6
Ecabet sodium 8.6
Ranitidine bismuth citrate 8.4
Whole human blood 7.9
Potassium citrate 7.4
H2SeO3 7.2
Moco 7.2
Zithromax 7.1
monobasic sodium phosphate 7.1
Hoelen 6.7
Orion 6.4
Omeprazole 6.4
Fenoprofen 6.2
Rize 6.2
Sterile water 5.9
NH3 5.8
AraC 5.7
Amoxicillin 5.7
Rasburicase 5.7
L-Asparaginase 5.7
EMB 5.6
Guar gum 5.6
Sodium benzoate 5.5
Cellulase 5.4
Tween 60 5.4
Ammonium chloride 5.2
Geranium 5.1
Tinidazole 5.0
beta-Galactosidase 4.9
Soybean oil 4.8
Nitazoxanide 4.8
SrCl2 4.7
AMC 4.7
CAZ 4.7
SrCl2 4.6
lactose 4.5
Dextrose 4.5
niacin 4.5
Rifaximin 4.4
Xylocaine 4.4
MEA 4.3
Gastro 4.3
OMP 4.2
Ginger 4.2
CEC 4.2
Sodium alginate 4.2
Indinavir 4.2
Asparaginase 4.1
Xylocaine 4.1
Furan 4.0
CER 4.0
Papain 4.0
Lactose 3.9
Bestatin 3.9
Bifidobacterium 3.9
CPO 3.8
Senna 3.8
Sumatran 3.8
Fipronil 3.8
Senna 3.8
Xylocaine 3.7
Gelatin 3.7
ampicillin 3.5
Cantor 3.5
CTT 3.4
Serum albumin 3.4
Hyaluronidase 3.3
ISP 3.2
Emodin 3.2
Monensin 3.2
Hyaluronidase 3.1
TAC 3.0
Acacia 3.0
Salicylate 3.0
Emodin 2.9
ABC 2.9
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Enzyme
urease 12.1
methylenediurease 12.1
urease 12.1
EC 3.5.3.2 11.1
hydantoin hydrolase 10.5
ureidoglycolate lyase 10.5
EC 2.6.1.14 10.1
urethanase 10.1
allantoate amidohydrolase 10.0
allantoicase 10.0
N-methylhydantoin amidohydrolase 9.5
allantoinase 9.5
imidazolonepropionase 9.3
ureidoglycolate hydrolase 9.1
formamidase 9.1
AtzB 8.9
lysine decarboxylase 8.8
citrulline ureidase 8.8
AtzC 8.6
phosphoglucosamine mutase 8.6
allophanate hydrolase 8.5
lactate racemase 8.4
nicotinamidase 8.3
creatininase 8.3
4-hydroxybenzoate 3-monooxygenase 8.1
leucine dehydrogenase 8.1
arginine deiminase 8.0
invertase 7.9
decarbonylase 7.9
omega-amidase 7.9
UDP-N-acetylglucosamine pyrophosphorylase 7.9
arylsulfatase 7.8
acetone carboxylase 7.8
beta-ureidopropionase 7.8
creatinase 7.7
creatinine iminohydrolase 7.7
EC 1.1.1.47 7.7
N-acetylglucosamine-6-phosphate deacetylase 7.6
imidase 7.5
histidase 7.2
IgA protease 7.1
sucrase 7.1
hydroxylamine reductase 7.1
hydroxylamine reductase 7.1
beta-glucosidase 7.0
tryptophanase 7.0
atrazine chlorohydrolase 7.0
beta-glucosidase 6.9
phosphoamidase 6.8
carbamate kinase 6.8
alanine aminopeptidase 6.8
nitrate reductase 6.7
methyl coenzyme M reductase 6.7
nitrate reductase 6.7
nitrate reductase 6.7
nitrate reductase 6.7
nitrate reductase 6.7
nitrate reductase 6.7
ornithine cyclodeaminase 6.7
hydrogenase 6.5
sulfatase 6.5
hydrogenase 6.5
uricase 6.5
arginase 6.4
mutanase 6.4
hyaluronate lyase 6.4
IgA1 protease 6.4
TDH 6.3
phosphoribosylanthranilate isomerase 6.3
dihydropyrimidinase 6.3
FTR 6.3
phenol oxidase 6.3
fructose-6-phosphate phosphoketolase 6.2
PepX 6.1
urocanase 6.1
levanase 6.1
cellulase 6.1
glutamate dehydrogenase 6.1
glutamate dehydrogenase 6.1
acid phosphatase 6.1
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Compound
Benurestat 12.1
(3,4-dichlorophenyl)acetic acid 12.1
ethyl hentriacontanoate 12.1
N-Benzylaniline 12.1
Flurofamide 11.8
3-methylbenzohydrazide 11.5
methyl triacontanoate 11.1
Meralluride 11.1
Polypodine B 11.1
Meralluride 11.1
methyl 3,4,5-trihydroxybenzoate 10.5
o-Cresolphthalein complexone 10.5
Evernic acid 10.1
2-cyclohepten-1-one 10.1
4-bromophenylboronic acid 10.1
Carfentrazone-ethyl 10.1
ureidoglycolate 10.0
1,3,4-thiadiazole-2(3H)-thione 9.8
2-hydroxy-1-phenylethanone 9.8
5-Nitroimidazole 9.8
Nonactin 9.5
4-methoxybenzohydrazide 9.5
4-chlorobenzenesulfonyl chloride 9.5
1,2,4-butanetricarboxylic acid 9.5
C6Cl4O2 9.5
Bromothymol blue 9.5
allantoate 9.2
methyl 3,4,5-trihydroxybenzoate 9.1
Remin 9.1
Poncirin 8.8
C6H10O4 8.8
2-hydroxy-1-phenylethanone 8.8
2-imidazolidinimine 8.6
Methylcitric acid 8.6
2-imidazolidinimine 8.6
2-formylbenzoic acid 8.5
CDMT 8.4
2-methyl-1H-benzimidazole 8.4
Esculin 8.4
4-hydroxyphenyl acetate 8.4
4-fluorobenzamide 8.3
1H-pyrazole-1-carbothioamide 8.2
Dicyandiamide 8.2
Pretilachlor 8.2
Benzohydroxamic acid 8.1
Rabeprazole sodium 8.0
1-triacontanol 8.0
Hydroxyatrazine 7.9
C2H5NO2 7.9
N,N-dimethylurea 7.7
1-naphthalenesulfonic acid 7.7
1-naphthalenesulfonic acid 7.7
selenic acid 7.6
selenic acid 7.6
Triphenylmethane 7.6
selenic acid 7.6
3-methylpiperidine 7.6
3-methylpiperidine 7.6
Brilliant Yellow 7.6
L-749 7.4
hydrazinecarboxamide 7.4
nicotinohydrazide 7.2
3-hydroxyhexadecanoic acid 7.2
2-piperidinone 7.2
2-hydroxy-4-methoxybenzaldehyde 7.1
Lansoprazole 7.1
diphenylacetic acid 7.1
Flavomycin 7.1
urea 7.0
Patchouli alcohol 7.0
Tuberculostearic acid 7.0
Canavanine 6.9
URP 6.9
Bronopol 6.9
1-vinyl-2-pyrrolidinone 6.8
1-phenyl-1,2-propanedione 6.8
ReSe2 6.8
Clarithromycin 6.8
Rabeprazole 6.8
dibenzo[b,d]furan 6.8
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