Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.5 (urease)
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Human Gene/Protein
OR51B5 10.1
Allantoicase 10.1
ASB1 10.0
OHCU decarboxylase 9.8
Kangai 1 9.8
TJ6 9.6
aquarius 9.5
Alkaline phosphomonoesterase 9.5
EFG2 9.3
CD300E 9.1
HAO2 9.1
ASB3 8.9
PPHA 8.8
CP11 8.8
KDEL receptor 1 8.8
integral membrane protein 2A 8.8
alkaline phosphomonoesterase 8.7
HLA-DRB1*0402 8.5
arylsulfatase 8.4
SAR1A 8.3
L-lactic dehydrogenase 8.2
beta-ureidopropionase 8.1
KAI1 protein 8.1
AK6 8.1
arylsulphatase 8.0
SLC14A1 8.0
AD 2 7.9
VPH1 7.9
ASB2 7.9
p62dok 7.8
beta-alanine synthase 7.7
CL-6 7.7
N-acetylglucosamine-6-phosphate deacetylase 7.7
SS1 7.7
UDP-N-acetylglucosamine pyrophosphorylase 7.5
ITSN 7.5
MND1 7.4
IPK1 7.4
transcription regulator protein 7.3
histidase 7.3
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Disease
Helicobacter-associated disease 11.1
Cervical Carcinoma 10.1
Chronic antral gastritis 9.8
Chronic superficial gastritis 9.8
tyrosinuria 9.3
Vestibular vertigo 9.3
Superficial gastritis 9.3
Gastric infection 9.3
urethrolithiasis 9.1
H pylori infection 9.0
Disseminated trichosporonosis 8.9
Proteus mirabilis infection 8.8
alcoholic gastritis 8.6
Helicobacter pylori infection 8.5
gastric mucosal atrophy 8.4
Chronic gastritis 8.4
Erosive esophagitis 8.2
gastritis 8.1
galactosuria 7.8
Brunner's gland hyperplasia 7.7
antritis 7.7
Ureaplasma infection 7.6
GUD 7.5
duodenitis 7.5
Upper gastrointestinal symptoms 7.4
Pulmonary coccidioidomycosis 7.4
acute gastritis 7.4
peptic ulcer 7.3
dyspepsia 7.3
bartholinitis 7.2
gastroduodenitis 7.2
Helicobacter pylori gastritis 7.2
Gastric lymphoma 7.2
orotic aciduria 7.2
duodenal ulcer 7.2
Proteus 7.2
TBCD 7.1
gastric ulcer 6.7
Digestive Diseases 6.6
OCM 6.6
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Symptom
Cloudy urine 10.1
Gastrointestinal distress 8.5
skin impairment 7.6
epigastric distress 6.5
Blanching 5.4
acid regurgitation 4.7
belching 4.4
acidity 4.1
epigastric pain 4.0
consciousness disturbance 4.0
forgetfulness 3.7
eds 3.6
heartburn 3.4
stomach pain 3.1
twitching 3.1
Gastrointestinal symptoms 2.9
pleuritic chest pain 2.9
neck stiffness 2.9
abdominal pain 2.5
intestinal bleeding 2.4
rigors 2.4
general problem 2.3
microbial colonization 2.0
Hudson 2.0
flank pain 2.0
agitation 2.0
productive cough 2.0
hypoproteinemia 2.0
lethargy 1.9
hypertonia 1.8
tachypnea 1.8
diarrhea 1.7
Wind 1.7
nasal discharge 1.7
starvation 1.6
vomiting 1.5
bloating 1.4
oliguria 1.2
nausea 1.2
acute abdominal pain 1.1
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Drug
Calcibind 12.1
Lithostat 12.1
Ammonia water 10.1
Troxipide 9.5
Oyster shell 8.6
Ecabet sodium 8.6
Ranitidine bismuth citrate 8.4
Whole human blood 7.9
Potassium citrate 7.4
H2SeO3 7.2
Moco 7.2
Zithromax 7.1
monobasic sodium phosphate 7.1
Hoelen 6.7
Orion 6.4
Omeprazole 6.4
Fenoprofen 6.2
Rize 6.2
Sterile water 5.9
NH3 5.8
AraC 5.7
Amoxicillin 5.7
Rasburicase 5.7
L-Asparaginase 5.7
EMB 5.6
Guar gum 5.6
Sodium benzoate 5.5
Cellulase 5.4
Tween 60 5.4
Ammonium chloride 5.2
Geranium 5.1
Tinidazole 5.0
beta-Galactosidase 4.9
Soybean oil 4.8
Nitazoxanide 4.8
SrCl2 4.7
AMC 4.7
CAZ 4.7
SrCl2 4.6
lactose 4.5
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Enzyme
urease 12.1
methylenediurease 12.1
urease 12.1
EC 3.5.3.2 11.1
hydantoin hydrolase 10.5
ureidoglycolate lyase 10.5
urethanase 10.1
EC 2.6.1.14 10.1
allantoate amidohydrolase 10.0
allantoicase 10.0
N-methylhydantoin amidohydrolase 9.5
allantoinase 9.5
imidazolonepropionase 9.3
ureidoglycolate hydrolase 9.1
formamidase 9.1
AtzB 8.9
lysine decarboxylase 8.8
citrulline ureidase 8.8
AtzC 8.6
phosphoglucosamine mutase 8.6
allophanate hydrolase 8.5
lactate racemase 8.4
nicotinamidase 8.3
creatininase 8.3
4-hydroxybenzoate 3-monooxygenase 8.1
leucine dehydrogenase 8.1
arginine deiminase 8.0
invertase 7.9
decarbonylase 7.9
omega-amidase 7.9
UDP-N-acetylglucosamine pyrophosphorylase 7.9
arylsulfatase 7.8
beta-ureidopropionase 7.8
acetone carboxylase 7.8
creatinase 7.7
creatinine iminohydrolase 7.7
EC 1.1.1.47 7.7
N-acetylglucosamine-6-phosphate deacetylase 7.6
imidase 7.5
histidase 7.2
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Compound
N-Benzylaniline 12.1
Benurestat 12.1
(3,4-dichlorophenyl)acetic acid 12.1
ethyl hentriacontanoate 12.1
Flurofamide 11.8
3-methylbenzohydrazide 11.5
Meralluride 11.1
methyl triacontanoate 11.1
Meralluride 11.1
Polypodine B 11.1
o-Cresolphthalein complexone 10.5
methyl 3,4,5-trihydroxybenzoate 10.5
4-bromophenylboronic acid 10.1
2-cyclohepten-1-one 10.1
Evernic acid 10.1
Carfentrazone-ethyl 10.1
ureidoglycolate 10.0
1,3,4-thiadiazole-2(3H)-thione 9.8
2-hydroxy-1-phenylethanone 9.8
5-Nitroimidazole 9.8
C6Cl4O2 9.5
1,2,4-butanetricarboxylic acid 9.5
Nonactin 9.5
4-methoxybenzohydrazide 9.5
Bromothymol blue 9.5
4-chlorobenzenesulfonyl chloride 9.5
allantoate 9.2
methyl 3,4,5-trihydroxybenzoate 9.1
Remin 9.1
2-hydroxy-1-phenylethanone 8.8
C6H10O4 8.8
Poncirin 8.8
2-imidazolidinimine 8.6
2-imidazolidinimine 8.6
Methylcitric acid 8.6
2-formylbenzoic acid 8.5
Esculin 8.4
CDMT 8.4
4-hydroxyphenyl acetate 8.4
2-methyl-1H-benzimidazole 8.4
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