Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.4 (deaminase)
 5,113 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The specificity of bovine spleen cathepsin B2 has been investigated by means of some natural oligo- and polypeptides, i.e. glucagon, melittin, insulin A and B chain, bradykinin, angiotensin I and II, oxytocin ACTH, clupein and salmin. The enzyme is primarily a carboxypeptidase which hydrolyzes peptide linkages of most amino acids common to proteins. In addition, cathepsin B2 displays amidase and esterase activity without requiring a free carboxyl group. The main pH optimum is between 4 and 5, in some cases higher.
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PMID:On the specificity of bovine spleen cathepsin B2. 1 11

Comprehensive studies were performed in Wistar rats on the relations between the dietary protein quality and the function of the adrenocortical system. The authors determined: the increase in body mass, the urea and corticosteroid concentrations in the blood plasma, the GOT (EC 2.6.I.I.) and GPT (EC 2.6.I.2.) activities in the liver, the reactivity of the adrenocortical system in vitro, the ACTH content in the hypophyses and the content of corticosteroid-binding globulin in the blood plasma. In adrenalectomized and normal rats as well as in rats treated with corticosterone or cortisol, the authors determined the GPT, GOT, amino-acid aryl amidase (EC 3.4.I.2.) and tripeptidase (EC 3.4.I.3.) activities in the liver and the mucosa of the small intestine, and the total, alpha and beta-amylase activities in the small intestine.
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PMID:[Relation between quality of dietary protein, plasma corticosteroid concentration and various enzyme activities in liver and mucosa of small intestine]. 17 7