Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.12 (biotinidase)
 392 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
biotinidase 392
Biotinidase 57
Mol 34
holocarboxylase synthetase 32
Sep 26
pyruvate carboxylase 16
histone 14
BTD 13
Holocarboxylase synthetase 11
MRI 8
She 7
acetyl-CoA carboxylase 6
cholesterol esterase 6
sodium-dependent multivitamin transporter 6
propionyl-CoA carboxylase 6
pyruvate dehydrogenase 5
microsomal 5
peroxidase 5
albumin 4
H2A 4
Vanin-1 4
galactose-1-phosphate uridyltransferase 3
monocarboxylate transporter 1 3
CSF 3
NBS 3
K18 3
hemoglobin 3
histone H3 3
SDS 3
thymus 3
glycoprotein 3
medium-chain acyl-CoA dehydrogenase 3
H2B 3
MCD 3
ATP 2
NHS 2
Boc 2
histone H2A 2
VNN2 2
polypeptide 2
more...
Disease
Biotinidase deficiency 87
phenylketonuria 30
metabolic disorder 21
developmental delay 21
rash 18
galactosemia 16
optic atrophy 16
maple syrup urine disease 15
homocystinuria 14
cystic fibrosis 14
congenital hypothyroidism 14
congenital adrenal hyperplasia 12
dermatitis 11
encephalopathy 8
Biotin deficiency 8
mental retardation 8
cancer 8
mental retardation 8
sensorineural hearing loss 7
deafness 7
lactic acidosis 6
epilepsy 6
sickle cell disease 6
hypoglycemia 6
seborrheic dermatitis 6
enzyme deficiency 6
fits 6
neuroblastoma 6
Leigh syndrome 5
hypothyroidism 5
tumor 5
glycogen storage disease 5
myelopathy 5
tyrosinemia 5
Multiple carboxylase deficiency 4
failure to thrive 4
West 4
neuropathy 4
hemoglobinopathies 4
liver disease 4
more...
Symptom
seizures 38
hypotonia 23
ataxia 22
paraparesis 9
lethargy 8
weakness 5
vomiting 3
dyspnea 3
myoclonus 2
ketonuria 2
anorexia 2
starvation 2
respiratory distress 2
hepatosplenomegaly 2
stridor 2
abnormal gait 2
tremor 2
hypertonia 2
spasticity 2
vertigo 1
fatigue 1
nausea 1
Spastic paraparesis 1
dry skin 1
wheezing 1
clonus 1
consciousness disturbance 1
erythema 1
tachypnea 1
dysarthria 1
ophthalmoplegia 1
dystonia 1
hepatomegaly 1
paresis 1
Drug
lysine 27
Dermatol 7
CSF 3
Spectrum 1
PTC 1
Ara-A 1
THF 1
Alanine 1
Spectrum 1
Vitamin B12 1
vitamin E 1
Enzyme
biotinidase 392
pyruvate carboxylase 17
acyl-CoA dehydrogenase 9
propionyl-CoA carboxylase 7
acetyl-CoA carboxylase 6
propionyl-CoA carboxylase 6
pyruvate dehydrogenase 5
pyruvate dehydrogenase 5
peroxidase 5
pyruvate dehydrogenase 5
deaminase 3
acyl-CoA dehydrogenase 2
holocarboxylase-synthetase 2
alpha-ketoglutarate dehydrogenase 2
trypsin 2
methylcrotonyl-CoA carboxylase 2
methylmalonyl-CoA mutase 2
pantetheinase 2
cystathionine gamma-synthase 1
DOPA decarboxylase 1
uridyltransferase 1
AMPK 1
ACS 1
protein kinase 1
EC 6.3.4.10 1
citrate synthase 1
KAT 1
ceruloplasmin 1
PNGase F 1
transcarboxylase 1
lipoprotein lipase 1
alanine aminotransferase 1
lipase 1
cytochrome oxidase 1
caspase-3 1
3-hydroxyacyl-CoA dehydrogenase 1
aspartate aminotransferase 1
delta-aminolevulinic acid dehydratase 1
succinate dehydrogenase 1
AMP-activated protein kinase 1
more...
Compound
Biotin 45
Clin 39
DNA 33
lysine 29
Dec 26
water 18
His 10
cysteine 10
sodium 9
Biocytin 9
CoA 9
phosphate 8
3-hydroxyisovaleric acid 8
zinc 7
serine 7
alanine 6
3-methylcrotonyl-CoA 5
sulfate 4
Phe 4
glucose 4
galactose 3
2-mercaptoethanol 3
NBS 3
ammonia 3
methionine 3
A 3 3
arginine 3
SDS 3
aspartic acid 2
Asp 2
leucine 2
ammonium 2
ACTH 2
chromium 2
TSH 2
aspartic acid 2
tyrosine 2
nitrogen 2
aspartic acid 2
17-OHP 2
more...