Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.12 (biotinidase)
 392 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
biotinidase 392
Biotinidase 57
Mol 34
holocarboxylase synthetase 32
Sep 26
pyruvate carboxylase 16
histone 14
BTD 13
Holocarboxylase synthetase 11
MRI 8
She 7
acetyl-CoA carboxylase 6
cholesterol esterase 6
sodium-dependent multivitamin transporter 6
propionyl-CoA carboxylase 6
peroxidase 5
microsomal 5
pyruvate dehydrogenase 5
H2A 4
Vanin-1 4
albumin 4
hemoglobin 3
SDS 3
CSF 3
thymus 3
K18 3
monocarboxylate transporter 1 3
MCD 3
histone H3 3
medium-chain acyl-CoA dehydrogenase 3
H2B 3
galactose-1-phosphate uridyltransferase 3
glycoprotein 3
NBS 3
K13 2
Boc 2
serum albumin 2
axonal 2
methylmalonyl-CoA mutase 2
B12 2
trypsinogen 2
VNN2 2
Sp1 2
AMP 2
insulin 2
polypeptide 2
ATP 2
histone H2A 2
Rett syndrome 2
GPI 2
acyl-CoA dehydrogenase 2
histone H4 2
K12 2
PKU 2
NHS 2
alternatively spliced 1
alpha-fetoprotein 1
thyroid hormone 1
anonymous 1
SLC5A6 1
reductase 1
casein 1
NOD 1
Pyruvate carboxylase 1
MC1 1
3-hydroxyacyl-CoA dehydrogenase 1
pantetheinase 1
nucleolin 1
brush border 1
X-linked adrenoleukodystrophy 1
SMVT 1
UTR 1
GPI-80 1
LHON 1
galactosamine 1
classical) 1
ABR 1
ACTH 1
nodal 1
PBS 1
S10 1
cryptic 1
nuclear protein 1
SPINK5 1
caspase-3 1
oxoglutarate 1
K23 1
GSD IX 1
glucose-6-phosphate dehydrogenase 1
aminoacylase 1
wts 1
dopa decarboxylase 1
aquaporin-4 1
AST 1
transferrin receptor 1
intestine, liver 1
solute carrier 1
ATP7A 1
beta-endorphin 1
dynorphin 1
chorionic gonadotropin 1
glucose transporter 1
X-linked 1
mer 1
DNA polymerase alpha 1
clusterin 1
K14 1
PTC 1
genomic clone 1
peptidase 1
PCC 1
thyroglobulin 1
lipoprotein lipase 1
threonine 1
N-acetyl-beta-glucosaminidase 1
SAH 1
L12a 1
MCT1 1
housekeeping 1
AGL 1
PTMA 1
G6Pase 1
Interferon-gamma 1
PPH 1
C15 1
IPL 1
EIF2B4 1
Walker 1
L12 1
TPC 1
mouse) 1
Pyruvate dehydrogenase 1
SLC19A3 1
porphobilinogen synthase 1
H2AX 1
ceruloplasmin 1
endoplasmic reticulum 1
liver glycogen phosphorylase 1
prothrombin 1
kit 1
DTNB 1
TNM 1
MSUD 1
N-glycanase 1
biotin carboxylase 1
CELL 1
2-oxoglutarate dehydrogenase 1
cytochrome c oxidase 1
thyrotropin-releasing hormone 1
mTOR 1
PER 1
lymphoid 1
SCD 1
RACE 1
TSK 1
alpha-1-antitrypsin 1
HEK 1
AMPK 1
alpha-ketoglutarate dehydrogenase 1
FRG 1
G6PD 1
ESI 1
Thyroid stimulating hormone receptor 1
ACS 1
B(0)AT1 1
lipase 1
PCCB 1
aminopeptidase 1
NARP 1
Sialidase 1
ACC2 1
chemokine 1
beta-ketothiolase 1
GAN 1
long-chain acyl-CoA dehydrogenase 1
CD4 1
NMR 1
very-long-chain acyl-CoA dehydrogenase 1
short-chain acyl-CoA dehydrogenase 1
MELAS 1
C17 1
Disease
Biotinidase deficiency 87
phenylketonuria 30
metabolic disorder 21
developmental delay 21
rash 18
optic atrophy 16
galactosemia 16
maple syrup urine disease 15
cystic fibrosis 14
homocystinuria 14
congenital hypothyroidism 14
congenital adrenal hyperplasia 12
dermatitis 11
mental retardation 8
mental retardation 8
Biotin deficiency 8
cancer 8
encephalopathy 8
sensorineural hearing loss 7
deafness 7
lactic acidosis 6
sickle cell disease 6
hypoglycemia 6
seborrheic dermatitis 6
epilepsy 6
fits 6
enzyme deficiency 6
neuroblastoma 6
tyrosinemia 5
Leigh syndrome 5
tumor 5
hypothyroidism 5
glycogen storage disease 5
myelopathy 5
liver disease 4
West 4
failure to thrive 4
hemoglobinopathies 4
Multiple carboxylase deficiency 4
neuropathy 4
malnutrition 3
NBS 3
MCD 3
eczema 3
stroke 3
SDS 3
conjunctivitis 3
candidiasis 2
myopathy 2
basal ganglia disease 2
hepatocellular carcinoma 2
autism 2
coma 2
multiple sclerosis 2
HMG-CoA lyase deficiency 2
vitamin E deficiency 2
papillary thyroid cancer 2
hyperglycemia 2
diabetes 2
ketosis 2
plaque 2
folate deficiency 2
congenital disorder 2
immune deficiency 2
thyroid cancer 2
Phenylketonuria 2
brain atrophy 2
cleft palate 2
genetic disorder 2
hemiparesis 2
Rett syndrome 2
cirrhosis 2
motor neuron disease 2
cold 2
ABL 2
tetraplegia 2
hemophagocytic lymphohistiocytosis 2
propionic acidemia 2
Holocarboxylase synthetase deficiency 2
depression 2
methylmalonic acidemia 2
glutaric aciduria 2
NHS 2
dysplasia 2
mild mental retardation 1
pheochromocytoma 1
megaloblastic anemia 1
APC 1
hypercalciuria 1
ALD 1
acrodermatitis enteropathica 1
Kearns-Sayre syndrome 1
hypermethioninemia 1
trichoptilosis 1
acute hepatitis 1
Organic acidemias 1
GCE 1
Waardenburg syndrome 1
HND 1
developmental disabilities 1
Kawasaki disease 1
MPS II 1
juvenile myelomonocytic leukemia 1
proteinuria 1
Sanfilippo syndrome 1
Hashimoto's thyroiditis 1
diabetic ketoacidosis 1
MPS VI 1
carcinogenesis 1
gastroenteritis 1
Trichorrhexis nodosa 1
dysphagia 1
anthrax 1
Menkes 1
congestive heart failure 1
Wolman disease 1
brittle hair 1
glycinuria 1
sarcoma 1
NOD 1
migraine 1
Hurler 1
anal atresia 1
Graves' disease 1
GSD IX 1
malabsorption 1
vitamin B6 deficiency 1
blindness 1
Coffin-Siris syndrome 1
infertility 1
microalbuminuria 1
PCC 1
MELAS 1
psoriasis 1
myelitis 1
acne 1
adrenal hyperplasia 1
Netherton syndrome 1
movement disorder 1
SCD 1
glioma 1
laryngospasm 1
Neuromyelitis optica 1
ornithine transcarbamylase deficiency 1
Syndrome 1
Thymus 1
Fanconi 1
Alzheimer's disease 1
Staphylococcus aureus meningitis 1
Wernicke's encephalopathy 1
bezoar 1
conversion reaction 1
syringomyelia 1
hepatitis 1
Ohtahara syndrome 1
tuberculosis 1
encephalitis 1
Gaucher disease 1
Tay-Sachs disease 1
Niemann-Pick 1
aggressiveness 1
PC deficiency 1
aminoaciduria 1
subacute sclerosing panencephalitis 1
kwashiorkor 1
Disorder 1
PDS 1
Thiamine-responsive megaloblastic anemia 1
MELAS 1
mitochondrial encephalomyopathy 1
astrocytoma 1
Miller Fisher syndrome 1
fungal infection 1
glaucoma 1
PER 1
paraplegia 1
spastic diplegia 1
hypofibrinogenemia 1
thalassemia 1
MCAD deficiency 1
Thymus 1
Epstein 1
disorders of amino acid metabolism 1
GSD I 1
infectious diseases 1
Down syndrome 1
SCID 1
optic neuritis 1
Forbes 1
rare disease 1
chronic liver disease 1
mitochondrial disease 1
hyperargininemia 1
pancytopenia 1
Hers 1
Congenital hypothyroidism 1
intraocular pressure 1
Alport syndrome 1
scotoma 1
Thymus 1
Vertebral anomalies 1
external genitalia 1
Peroxisomal disorders 1
hypervitaminosis 1
blepharitis 1
hypovitaminosis 1
quadriparesis 1
AMD 1
IVA 1
Friedreich's ataxia 1
Inborn errors of metabolism 1
MSD 1
vasculitis 1
confusion 1
Medulla 1
blepharoconjunctivitis 1
viral hepatitis 1
esophageal atresia 1
Autism 1
tuberous sclerosis 1
dyspepsia 1
atopic dermatitis 1
leukoencephalopathy 1
Norrie disease 1
Other metabolic disorders 1
magnesium deficiency 1
Autism spectrum disorder 1
Symptom
seizures 38
hypotonia 23
ataxia 22
paraparesis 9
lethargy 8
weakness 5
vomiting 3
dyspnea 3
myoclonus 2
ketonuria 2
anorexia 2
starvation 2
respiratory distress 2
hepatosplenomegaly 2
stridor 2
abnormal gait 2
tremor 2
hypertonia 2
spasticity 2
vertigo 1
fatigue 1
nausea 1
Spastic paraparesis 1
dry skin 1
wheezing 1
clonus 1
consciousness disturbance 1
erythema 1
tachypnea 1
dysarthria 1
ophthalmoplegia 1
dystonia 1
hepatomegaly 1
paresis 1
Drug
lysine 27
Dermatol 7
CSF 3
Spectrum 1
PTC 1
Ara-A 1
THF 1
Alanine 1
Spectrum 1
Vitamin B12 1
vitamin E 1
Enzyme
biotinidase 392
pyruvate carboxylase 17
acyl-CoA dehydrogenase 9
propionyl-CoA carboxylase 7
propionyl-CoA carboxylase 6
acetyl-CoA carboxylase 6
pyruvate dehydrogenase 5
pyruvate dehydrogenase 5
peroxidase 5
pyruvate dehydrogenase 5
deaminase 3
acyl-CoA dehydrogenase 2
trypsin 2
alpha-ketoglutarate dehydrogenase 2
methylmalonyl-CoA mutase 2
methylcrotonyl-CoA carboxylase 2
pantetheinase 2
holocarboxylase-synthetase 2
cystathionine gamma-synthase 1
DOPA decarboxylase 1
uridyltransferase 1
AMPK 1
ACS 1
protein kinase 1
AMPK 1
DNA polymerase 1
AST 1
KAT 1
ceruloplasmin 1
PNGase F 1
glucose-6-phosphate dehydrogenase 1
lipoprotein lipase 1
transcarboxylase 1
alanine aminotransferase 1
lipase 1
cytochrome oxidase 1
citrate synthase 1
EC 6.3.4.10 1
caspase-3 1
3-hydroxyacyl-CoA dehydrogenase 1
aspartate aminotransferase 1
delta-aminolevulinic acid dehydratase 1
succinate dehydrogenase 1
AMP-activated protein kinase 1
3-hydroxyacyl-CoA dehydrogenase 1
Compound
Biotin 45
Clin 39
DNA 33
lysine 29
Dec 26
water 18
cysteine 10
His 10
Biocytin 9
CoA 9
sodium 9
phosphate 8
3-hydroxyisovaleric acid 8
zinc 7
serine 7
alanine 6
3-methylcrotonyl-CoA 5
sulfate 4
Phe 4
glucose 4
ammonia 3
2-mercaptoethanol 3
SDS 3
NBS 3
A 3 3
methionine 3
galactose 3
arginine 3
acetone 2
urea 2
tyrosine 2
aspartic acid 2
ammonium 2
ACTH 2
chromium 2
leucine 2
TSH 2
nitrogen 2
iodine 2
aspartic acid 2
aspartic acid 2
EDTA 2
Valproic acid 2
17-OHP 2
DEAE 2
Histone 2
glutamate 2
valine 2
silver 2
EDTA 2
AMP 2
aspartic acid 2
Valproic acid 2
Asp 2
ATP 2
benzoic acid 1
barium 1
sodium chloride 1
octyl 1
Sialic acid 1
thiourea 1
DFO 1
nonanoic acid 1
tryptophan 1
HABA 1
Alanine 1
nonanoic acid 1
glutamine 1
Serine 1
Taurine 1
creatinine 1
diacetate 1
copper 1
Cbl 1
tryptophan 1
ACS 1
ACS 1
Desthiobiotin 1
glutamic acid 1
LIN 1
aldehyde 1
molybdenum 1
calcium 1
MTT 1
Neuronal 1
chromate 1
PTMA 1
nonanoic acid 1
aldehyde 1
HCl 1
isoleucine 1
Neu5Ac 1
TPB 1
octyl 1
SAH 1
Lactate 1
ethyl acetate 1
ethanol 1
glutaryl-CoA 1
nonanoic acid 1
octyl 1
Thyroid 1
hydroxylamine 1
Ara-A 1
phenylmethanesulfonamide 1
acetic acid 1
Vigabatrin 1
PAC 1
folinic acid 1
potassium 1
piperazine 1
BCG 1
glycerol 1
tryptophan 1
4-chloro-1-naphthol 1
PEG 1
DTPA 1
hydroxylamine 1
threonine 1
tryptophan 1
homocysteine 1
acetate 1
methanol 1
Ile 1
isopropanol 1
5-Aza-2'-deoxycytidine 1
nonanoic acid 1
S-adenosylhomocysteine 1
TNM 1
Pac 1
PABA 1
Pyruvate 1
isoleucine 1
Lip 1