Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.12 (biotinidase)
 392 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
biotinidase 392
Biotinidase 57
Mol 34
holocarboxylase synthetase 32
Sep 26
pyruvate carboxylase 16
histone 14
BTD 13
Holocarboxylase synthetase 11
MRI 8
She 7
cholesterol esterase 6
sodium-dependent multivitamin transporter 6
propionyl-CoA carboxylase 6
acetyl-CoA carboxylase 6
microsomal 5
peroxidase 5
pyruvate dehydrogenase 5
Vanin-1 4
H2A 4
albumin 4
galactose-1-phosphate uridyltransferase 3
SDS 3
glycoprotein 3
hemoglobin 3
medium-chain acyl-CoA dehydrogenase 3
CSF 3
MCD 3
histone H3 3
NBS 3
monocarboxylate transporter 1 3
K18 3
H2B 3
thymus 3
methylmalonyl-CoA mutase 2
histone H4 2
serum albumin 2
axonal 2
B12 2
K13 2
acyl-CoA dehydrogenase 2
K12 2
trypsinogen 2
VNN2 2
ATP 2
polypeptide 2
insulin 2
Boc 2
histone H2A 2
GPI 2
AMP 2
Sp1 2
Rett syndrome 2
PKU 2
NHS 2
alternatively spliced 1
alpha-fetoprotein 1
thyroid hormone 1
anonymous 1
SLC5A6 1
reductase 1
casein 1
NOD 1
Pyruvate carboxylase 1
MC1 1
3-hydroxyacyl-CoA dehydrogenase 1
pantetheinase 1
nucleolin 1
brush border 1
X-linked adrenoleukodystrophy 1
SMVT 1
UTR 1
GPI-80 1
LHON 1
galactosamine 1
classical) 1
ABR 1
ACTH 1
nodal 1
PBS 1
S10 1
cryptic 1
nuclear protein 1
SCD 1
TSK 1
caspase-3 1
ESI 1
G6PD 1
glucose-6-phosphate dehydrogenase 1
dopa decarboxylase 1
ACS 1
transferrin receptor 1
intestine, liver 1
solute carrier 1
ACC2 1
GAN 1
X-linked 1
mer 1
DNA polymerase alpha 1
clusterin 1
K14 1
PTC 1
genomic clone 1
peptidase 1
PCC 1
thyroglobulin 1
lipoprotein lipase 1
threonine 1
N-acetyl-beta-glucosaminidase 1
SAH 1
L12a 1
MCT1 1
housekeeping 1
AGL 1
PTMA 1
G6Pase 1
Walker 1
L12 1
TPC 1
mouse) 1
Pyruvate dehydrogenase 1
SLC19A3 1
Interferon-gamma 1
PPH 1
C15 1
IPL 1
EIF2B4 1
porphobilinogen synthase 1
H2AX 1
ceruloplasmin 1
endoplasmic reticulum 1
liver glycogen phosphorylase 1
prothrombin 1
TNM 1
MSUD 1
N-glycanase 1
biotin carboxylase 1
CELL 1
kit 1
DTNB 1
PER 1
lymphoid 1
RACE 1
alpha-1-antitrypsin 1
HEK 1
AMPK 1
alpha-ketoglutarate dehydrogenase 1
2-oxoglutarate dehydrogenase 1
cytochrome c oxidase 1
thyrotropin-releasing hormone 1
mTOR 1
lipase 1
PCCB 1
aminopeptidase 1
NARP 1
Sialidase 1
chemokine 1
long-chain acyl-CoA dehydrogenase 1
CD4 1
NMR 1
more...
Disease
Biotinidase deficiency 87
phenylketonuria 30
metabolic disorder 21
developmental delay 21
rash 18
galactosemia 16
optic atrophy 16
maple syrup urine disease 15
homocystinuria 14
congenital hypothyroidism 14
cystic fibrosis 14
congenital adrenal hyperplasia 12
dermatitis 11
encephalopathy 8
cancer 8
mental retardation 8
mental retardation 8
Biotin deficiency 8
sensorineural hearing loss 7
deafness 7
hypoglycemia 6
lactic acidosis 6
seborrheic dermatitis 6
epilepsy 6
sickle cell disease 6
fits 6
enzyme deficiency 6
neuroblastoma 6
tyrosinemia 5
glycogen storage disease 5
tumor 5
Leigh syndrome 5
hypothyroidism 5
myelopathy 5
hemoglobinopathies 4
liver disease 4
failure to thrive 4
Multiple carboxylase deficiency 4
neuropathy 4
West 4
conjunctivitis 3
stroke 3
NBS 3
eczema 3
MCD 3
malnutrition 3
SDS 3
HMG-CoA lyase deficiency 2
hyperglycemia 2
candidiasis 2
multiple sclerosis 2
congenital disorder 2
thyroid cancer 2
immune deficiency 2
glutaric aciduria 2
vitamin E deficiency 2
Phenylketonuria 2
papillary thyroid cancer 2
basal ganglia disease 2
plaque 2
folate deficiency 2
ketosis 2
diabetes 2
hemophagocytic lymphohistiocytosis 2
ABL 2
Rett syndrome 2
depression 2
cold 2
cirrhosis 2
tetraplegia 2
coma 2
genetic disorder 2
autism 2
hepatocellular carcinoma 2
propionic acidemia 2
Holocarboxylase synthetase deficiency 2
brain atrophy 2
methylmalonic acidemia 2
myopathy 2
motor neuron disease 2
cleft palate 2
hemiparesis 2
NHS 2
dysplasia 2
mild mental retardation 1
pheochromocytoma 1
megaloblastic anemia 1
APC 1
hypercalciuria 1
ALD 1
acrodermatitis enteropathica 1
Kearns-Sayre syndrome 1
hypermethioninemia 1
trichoptilosis 1
acute hepatitis 1
Organic acidemias 1
GCE 1
Waardenburg syndrome 1
HND 1
developmental disabilities 1
Kawasaki disease 1
MPS II 1
juvenile myelomonocytic leukemia 1
proteinuria 1
Sanfilippo syndrome 1
Hashimoto's thyroiditis 1
diabetic ketoacidosis 1
MPS VI 1
carcinogenesis 1
gastroenteritis 1
Trichorrhexis nodosa 1
dysphagia 1
anthrax 1
tuberculosis 1
Ohtahara syndrome 1
glycinuria 1
Gaucher disease 1
aminoaciduria 1
Hurler 1
Disorder 1
Thiamine-responsive megaloblastic anemia 1
blindness 1
Coffin-Siris syndrome 1
infertility 1
Graves' disease 1
malabsorption 1
vitamin B6 deficiency 1
mitochondrial encephalomyopathy 1
MELAS 1
glaucoma 1
acne 1
adrenal hyperplasia 1
MCAD deficiency 1
Thymus 1
glioma 1
Thymus 1
Fanconi 1
ornithine transcarbamylase deficiency 1
Alzheimer's disease 1
movement disorder 1
Down syndrome 1
Niemann-Pick 1
aggressiveness 1
mitochondrial disease 1
Neuromyelitis optica 1
Wernicke's encephalopathy 1
bezoar 1
hyperargininemia 1
Miller Fisher syndrome 1
conversion reaction 1
paraplegia 1
spastic diplegia 1
hypofibrinogenemia 1
Vertebral anomalies 1
disorders of amino acid metabolism 1
GSD I 1
AMD 1
optic neuritis 1
Forbes 1
vasculitis 1
more...
Symptom
seizures 38
hypotonia 23
ataxia 22
paraparesis 9
lethargy 8
weakness 5
vomiting 3
dyspnea 3
myoclonus 2
ketonuria 2
anorexia 2
starvation 2
respiratory distress 2
hepatosplenomegaly 2
stridor 2
abnormal gait 2
tremor 2
hypertonia 2
spasticity 2
vertigo 1
fatigue 1
nausea 1
Spastic paraparesis 1
dry skin 1
wheezing 1
clonus 1
consciousness disturbance 1
erythema 1
tachypnea 1
dysarthria 1
ophthalmoplegia 1
dystonia 1
hepatomegaly 1
paresis 1
Drug
lysine 27
Dermatol 7
CSF 3
Spectrum 1
PTC 1
Ara-A 1
THF 1
Alanine 1
Spectrum 1
Vitamin B12 1
vitamin E 1
Enzyme
biotinidase 392
pyruvate carboxylase 17
acyl-CoA dehydrogenase 9
propionyl-CoA carboxylase 7
propionyl-CoA carboxylase 6
acetyl-CoA carboxylase 6
pyruvate dehydrogenase 5
pyruvate dehydrogenase 5
peroxidase 5
pyruvate dehydrogenase 5
deaminase 3
acyl-CoA dehydrogenase 2
trypsin 2
alpha-ketoglutarate dehydrogenase 2
methylmalonyl-CoA mutase 2
methylcrotonyl-CoA carboxylase 2
pantetheinase 2
holocarboxylase-synthetase 2
cystathionine gamma-synthase 1
DOPA decarboxylase 1
uridyltransferase 1
AMPK 1
ACS 1
protein kinase 1
AMPK 1
DNA polymerase 1
AST 1
KAT 1
ceruloplasmin 1
PNGase F 1
glucose-6-phosphate dehydrogenase 1
lipoprotein lipase 1
transcarboxylase 1
alanine aminotransferase 1
lipase 1
cytochrome oxidase 1
citrate synthase 1
EC 6.3.4.10 1
caspase-3 1
3-hydroxyacyl-CoA dehydrogenase 1
aspartate aminotransferase 1
delta-aminolevulinic acid dehydratase 1
succinate dehydrogenase 1
AMP-activated protein kinase 1
3-hydroxyacyl-CoA dehydrogenase 1
Compound
Biotin 45
Clin 39
DNA 33
lysine 29
Dec 26
water 18
cysteine 10
His 10
Biocytin 9
CoA 9
sodium 9
phosphate 8
3-hydroxyisovaleric acid 8
zinc 7
serine 7
alanine 6
3-methylcrotonyl-CoA 5
sulfate 4
Phe 4
glucose 4
ammonia 3
2-mercaptoethanol 3
SDS 3
NBS 3
A 3 3
methionine 3
galactose 3
arginine 3
acetone 2
urea 2
tyrosine 2
aspartic acid 2
ammonium 2
ACTH 2
chromium 2
leucine 2
TSH 2
nitrogen 2
iodine 2
aspartic acid 2
aspartic acid 2
EDTA 2
Valproic acid 2
17-OHP 2
DEAE 2
Histone 2
glutamate 2
valine 2
silver 2
EDTA 2
AMP 2
aspartic acid 2
Valproic acid 2
Asp 2
ATP 2
benzoic acid 1
barium 1
sodium chloride 1
octyl 1
Sialic acid 1
thiourea 1
DFO 1
nonanoic acid 1
tryptophan 1
HABA 1
Alanine 1
nonanoic acid 1
glutamine 1
Serine 1
Taurine 1
creatinine 1
diacetate 1
copper 1
Cbl 1
tryptophan 1
ACS 1
ACS 1
Desthiobiotin 1
glutamic acid 1
LIN 1
aldehyde 1
molybdenum 1
calcium 1
MTT 1
Neuronal 1
chromate 1
PTMA 1
nonanoic acid 1
aldehyde 1
HCl 1
isoleucine 1
Neu5Ac 1
TPB 1
octyl 1
SAH 1
Lactate 1
ethyl acetate 1
ethanol 1
glutaryl-CoA 1
nonanoic acid 1
octyl 1
Thyroid 1
hydroxylamine 1
Ara-A 1
phenylmethanesulfonamide 1
acetic acid 1
Vigabatrin 1
PAC 1
folinic acid 1
potassium 1
piperazine 1
BCG 1
glycerol 1
tryptophan 1
4-chloro-1-naphthol 1
PEG 1
DTPA 1
hydroxylamine 1
threonine 1
tryptophan 1
homocysteine 1
acetate 1
methanol 1
Ile 1
isopropanol 1
5-Aza-2'-deoxycytidine 1
nonanoic acid 1
S-adenosylhomocysteine 1
TNM 1
Pac 1
PABA 1
Pyruvate 1
isoleucine 1
Lip 1