Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.1 (asparaginase)
2,695 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
L-asparaginase 1504
glutaminase 167
Sep 163
ALL 114
asparagine synthetase 101
PEG 92
Mol 69
fibrinogen 64
Pseudomonas 60
ASP 59
antithrombin 56
lymphoid 48
asp 45
antithrombin III 41
SDS 39
insulin 37
non-Hodgkin's lymphoma 36
thrombin 36
L-glutaminase 30
CHOP 30
SMILE 30
plasminogen 29
P-glycoprotein 29
threonine 28
protein C 25
She 25
glutamine synthetase 24
prothrombin 24
Pol 22
ara 21
HLA 20
CD10 20
polypeptide 20
mTOR 20
TEL 19
MTX 19
protein S 19
amylase 18
CD56 18
albumin 17
thromboplastin 16
ATP 16
hemoglobin 16
LDH 15
Gen 15
acid phosphatase 15
lactate dehydrogenase 15
MOLT 15
CD19 14
CD4 14
serum albumin 14
Glutaminase 14
AML 13
glutamate dehydrogenase 13
IgE 13
CD7 13
p53 12
alkaline phosphatase 12
peroxidase 12
BCR 12
lipase 12
FAB 12
NMR 12
fused 11
CBT 11
MLL 11
esterase 11
HLA-DR 11
AML1 11
ABL 11
SOD 10
CD34 10
ACS 10
VIII 10
endoplasmic reticulum 10
myeloperoxidase 10
Bcl-2 10
MRI 10
glycosylasparaginase 9
CD2 9
more...
Disease
acute lymphoblastic leukemia 892
leukemia 525
cancer 505
lymphoma 311
tumor 209
childhood ALL 136
pancreatitis 106
Leukemia 94
T-cell lymphoma 90
acute myeloid leukemia 86
acute leukemia 69
adult ALL 62
Epstein 52
hyperglycemia 50
acute pancreatitis 43
non-Hodgkin's lymphoma 43
lymphoblastic leukemia 43
T-cell acute lymphoblastic leukemia 42
SDS 39
coagulopathy 36
neutropenia 34
myelosuppression 34
Hodgkin's disease 34
thrombocytopenia 32
disseminated intravascular coagulation 31
minimal residual disease 30
diabetes 30
anaphylaxis 28
sepsis 28
sepsis 25
chronic myeloid leukemia 23
lymphosarcoma 23
B-ALL 22
T-cell lymphomas 21
encephalopathy 21
hypofibrinogenemia 20
childhood cancer 19
lymphadenopathy 19
hyperlipidemia 17
obesity 17
tumor growth 16
multiple myeloma 15
Farber 14
carcinoma 14
hematologic malignancies 13
acute nonlymphocytic leukemia 13
pneumonia 13
ovarian cancer 13
depression 13
hypercalcemia 12
hyperbilirubinemia 12
stroke 12
CEM 11
ABL 11
Burkitt's lymphoma 11
peripheral neuropathy 11
MCF 10
NK-cell leukemia 10
anemia 10
Mycobacterium 9
cold 9
fits 9
graft-versus-host disease 9
adenocarcinoma 9
hypertension 9
pulmonary embolism 9
blast crisis 8
Childhood Leukemia 8
coma 8
leukoencephalopathy 8
infectious diseases 8
glucose intolerance 8
acute promyelocytic leukemia 8
SCID 8
chronic lymphocytic leukemia 8
tumor progression 8
sarcoma 8
pseudotuberculosis 7
hepatitis 7
NHL 7
more...
Symptom
seizures 34
vomiting 30
starvation 26
nausea 23
diarrhea 17
headache 17
abdominal pain 16
agitation 14
splenomegaly 10
pain 10
hepatosplenomegaly 10
anorexia 9
nausea and vomiting 7
fatigue 7
weakness 7
tremor 6
hepatomegaly 5
hypoproteinemia 5
dyspnea 4
polyuria 4
Ill 3
polydipsia 3
epigastric pain 3
erythema 3
lethargy 3
analgesia 3
chills 2
discomfort 2
discomfort 2
ataxia 2
nasal congestion 2
acidity 2
blurred vision 2
pallor 2
ketonuria 2
sleepiness 2
overweight 2
hemiplegia 2
arthralgia 2
cerebellar ataxia 1
fever of unknown origin 1
flank pain 1
exhaustion 1
wheezing 1
flushing 1
decreased appetite 1
Sedation 1
asthenia 1
insomnia 1
chest pain 1
back pain 1
respiratory distress 1
ataxic gait 1
paraparesis 1
Welt 1
constipation 1
cough 1
autodigestion 1
acute abdominal pain 1
low back pain 1
dizziness 1
myalgia 1
nasal discharge 1
collapse 1
syncope 1
dystonia 1
hypothermia 1
tachypnea 1
hip pain 1
paresthesia 1
skin irritation 1
anal pain 1
Drug
Asparaginase 194
L-Asparaginase 103
Asn 39
Pegaspargase 29
lysine 20
Adriamycin 13
CTX 12
TEL 11
lactose 9
CSF 8
Oncaspar 7
AraC 7
ARA-C 6
G-CSF 6
Bayer 5
Dermatol 5
Gel 5
Etoposide 5
Prednisolone 5
NH3 4
Bortezomib 4
Leaf 4
Antithrombin III 4
DNase I 3
Growth hormone 3
citric acid 3
MgSO4 3
VCR 3
ROC 3
NADH 3
TAT 3
Prednisone 3
Growth hormone 3
Docetaxel 2
THF 2
Clofarabine 2
Teniposide 2
ADR 2
Taxotere 2
Monit 2
VCR 2
Maltose 2
ROS 2
RSM 2
Idarubicin 2
Dextrose 2
BLM 2
Nephron 1
ETS 1
Serum albumin 1
Dial 1
Mineral oil 1
NBT 1
Sodium citrate 1
Biopolymers 1
Glutamic acid 1
Dexrazoxane 1
CFS 1
AZT 1
Rituximab 1
Vitamin K 1
Sodium citrate 1
TTC 1
Theophylline 1
THA 1
APD 1
Ouabain 1
Glycerol 1
Fructose 1
PCB 1
ADM 1
Mutagen 1
Pegademase bovine 1
Ethanol 1
Acyclovir 1
Cellulose acetate 1
ABC 1
ascorbate 1
Ranitidine 1
Adenosine deaminase 1
more...
Enzyme
asparaginase 2695
glutaminase 193
asparagine synthetase 103
thrombin 35
P-glycoprotein 29
APC 29
trypsin 26
urease 25
urease 25
glutamine synthetase 24
CD10 22
lactate dehydrogenase 20
peroxidase 20
thromboplastin 19
deaminase 19
glutamate dehydrogenase 15
focal adhesion kinase 15
glutamate dehydrogenase 15
acid phosphatase 15
glutamate dehydrogenase 14
lipase 13
alkaline phosphatase 12
aspartate aminotransferase 12
ACS 10
alanine aminotransferase 9
arginase 9
aspartase 9
L-asparagine synthetase 8
ERK 8
cellulase 8
BMT 8
catalase 8
protein kinase 8
aspartylglucosaminidase 7
mitogen-activated protein kinase 7
chymotrypsin 7
caspase-3 7
topoisomerase 7
carboxypeptidase Y 7
glutamate synthase 7
glutamate synthase 6
adenosine deaminase 6
adenosine deaminase 6
tyrosinase 6
lipoprotein lipase 6
histidase 6
glutamate synthase 6
invertase 5
beta-galactosidase 5
cathepsin B 5
lysozyme 5
arginine deiminase 5
gamma-glutamyl transpeptidase 5
RNA polymerase 5
ricin 5
topoisomerase 5
beta-secretase 5
superoxide dismutase 5
PARP 4
thiopurine methyltransferase 4
glutamic dehydrogenase 4
luciferase 4
TdT 4
phospholipase C 4
creatine kinase 4
RNase 4
RNase 4
glucose oxidase 4
alcohol dehydrogenase 4
methylenetetrahydrofolate reductase 3
hyaluronidase 3
beta-glucosidase 3
pyruvate kinase 3
MDP 3
TAT 3
asparaginyl-tRNA synthetase 3
cholinesterase 3
ribonuclease 3
ACE 3
glutathione S-transferase 3
more...
Compound
asparagine 606
glutamine 198
Dec 169
Clin 138
PEG 134
Asp 134
nitrogen 132
DNA 116
ammonia 107
aspartic acid 104
PEG 102
glucose 88
acrylamide 78
ammonium 77
aspartic acid 63
aspartic acid 59
aspartic acid 59
sodium 57
sulfate 47
glutamate 47
water 43
SDS 41
urea 39
threonine 38
oxygen 37
Methotrexate 37
Ara-C 35
MTT 30
His 29
Ara-C 27
phosphate 26
alanine 26
arginine 26
serine 25
calcium 25
glutamic acid 24
lysine 24
methionine 23
proline 21
tyrosine 20
cysteine 19
MTX 19
hydrogen 18
Glutamine 18
NH2 17
VP-16 17
salt 17
Adriamycin 17
ATP 16
ethanol 16
zinc 16
DEAE 16
potassium 15
Vincristine 15
Optimal 14
leucine 12
norvaline 12
BCR 12
galactose 12
VM-26 12
CTX 12
norvaline 12
Phe 11
ABL 11
TEL 11
nickel 11
EDTA 11
EDTA 11
ACS 10
pyrimidine 10
acetate 10
Gly 10
ACS 10
glycerol 10
pyrimidine 10
6-Mercaptopurine 10
tryptophan 9
tryptophan 9
phenol 9
nitrate 9
more...