Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.5.1.1 (
asparaginase
)
2,695
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
L-asparaginase
1504
glutaminase
167
Sep
163
ALL
114
asparagine synthetase
101
PEG
92
Mol
69
fibrinogen
64
Pseudomonas
60
ASP
59
antithrombin
56
lymphoid
48
asp
45
antithrombin III
41
SDS
39
insulin
37
non-Hodgkin's lymphoma
36
thrombin
36
L-glutaminase
30
CHOP
30
SMILE
30
plasminogen
29
P-glycoprotein
29
threonine
28
protein C
25
She
25
glutamine synthetase
24
prothrombin
24
Pol
22
ara
21
HLA
20
CD10
20
polypeptide
20
mTOR
20
TEL
19
MTX
19
protein S
19
amylase
18
CD56
18
albumin
17
thromboplastin
16
ATP
16
hemoglobin
16
LDH
15
Gen
15
acid phosphatase
15
lactate dehydrogenase
15
MOLT
15
CD19
14
CD4
14
serum albumin
14
Glutaminase
14
AML
13
glutamate dehydrogenase
13
IgE
13
CD7
13
p53
12
alkaline phosphatase
12
peroxidase
12
BCR
12
lipase
12
FAB
12
NMR
12
fused
11
CBT
11
MLL
11
esterase
11
HLA-DR
11
AML1
11
ABL
11
SOD
10
CD34
10
ACS
10
VIII
10
endoplasmic reticulum
10
myeloperoxidase
10
Bcl-2
10
MRI
10
glycosylasparaginase
9
CD2
9
more...
Disease
acute lymphoblastic leukemia
892
leukemia
525
cancer
505
lymphoma
311
tumor
209
childhood ALL
136
pancreatitis
106
Leukemia
94
T-cell lymphoma
90
acute myeloid leukemia
86
acute leukemia
69
adult ALL
62
Epstein
52
hyperglycemia
50
acute pancreatitis
43
non-Hodgkin's lymphoma
43
lymphoblastic leukemia
43
T-cell acute lymphoblastic leukemia
42
SDS
39
coagulopathy
36
neutropenia
34
myelosuppression
34
Hodgkin's disease
34
thrombocytopenia
32
disseminated intravascular coagulation
31
minimal residual disease
30
diabetes
30
anaphylaxis
28
sepsis
28
sepsis
25
chronic myeloid leukemia
23
lymphosarcoma
23
B-ALL
22
T-cell lymphomas
21
encephalopathy
21
hypofibrinogenemia
20
childhood cancer
19
lymphadenopathy
19
hyperlipidemia
17
obesity
17
tumor growth
16
multiple myeloma
15
Farber
14
carcinoma
14
hematologic malignancies
13
acute nonlymphocytic leukemia
13
pneumonia
13
ovarian cancer
13
depression
13
hypercalcemia
12
hyperbilirubinemia
12
stroke
12
CEM
11
ABL
11
Burkitt's lymphoma
11
peripheral neuropathy
11
MCF
10
NK-cell leukemia
10
anemia
10
Mycobacterium
9
cold
9
fits
9
graft-versus-host disease
9
adenocarcinoma
9
hypertension
9
pulmonary embolism
9
blast crisis
8
Childhood Leukemia
8
coma
8
leukoencephalopathy
8
infectious diseases
8
glucose intolerance
8
acute promyelocytic leukemia
8
SCID
8
chronic lymphocytic leukemia
8
tumor progression
8
sarcoma
8
pseudotuberculosis
7
hepatitis
7
NHL
7
more...
Symptom
seizures
34
vomiting
30
starvation
26
nausea
23
diarrhea
17
headache
17
abdominal pain
16
agitation
14
splenomegaly
10
pain
10
hepatosplenomegaly
10
anorexia
9
nausea and vomiting
7
fatigue
7
weakness
7
tremor
6
hepatomegaly
5
hypoproteinemia
5
dyspnea
4
polyuria
4
Ill
3
polydipsia
3
epigastric pain
3
erythema
3
lethargy
3
analgesia
3
chills
2
discomfort
2
discomfort
2
ataxia
2
nasal congestion
2
acidity
2
blurred vision
2
pallor
2
ketonuria
2
sleepiness
2
overweight
2
hemiplegia
2
arthralgia
2
cerebellar ataxia
1
fever of unknown origin
1
flank pain
1
exhaustion
1
wheezing
1
flushing
1
decreased appetite
1
Sedation
1
asthenia
1
insomnia
1
chest pain
1
back pain
1
respiratory distress
1
ataxic gait
1
paraparesis
1
Welt
1
constipation
1
cough
1
autodigestion
1
acute abdominal pain
1
low back pain
1
dizziness
1
myalgia
1
nasal discharge
1
collapse
1
syncope
1
dystonia
1
hypothermia
1
tachypnea
1
hip pain
1
paresthesia
1
skin irritation
1
anal pain
1
Drug
Asparaginase
194
L-Asparaginase
103
Asn
39
Pegaspargase
29
lysine
20
Adriamycin
13
CTX
12
TEL
11
lactose
9
CSF
8
Oncaspar
7
AraC
7
ARA-C
6
G-CSF
6
Bayer
5
Dermatol
5
Gel
5
Etoposide
5
Prednisolone
5
NH3
4
Bortezomib
4
Leaf
4
Antithrombin III
4
DNase I
3
Growth hormone
3
citric acid
3
MgSO4
3
VCR
3
ROC
3
NADH
3
TAT
3
Prednisone
3
Growth hormone
3
Docetaxel
2
THF
2
Clofarabine
2
Teniposide
2
ADR
2
Taxotere
2
Monit
2
VCR
2
Maltose
2
ROS
2
RSM
2
Idarubicin
2
Dextrose
2
BLM
2
Nephron
1
ETS
1
Serum albumin
1
Dial
1
Mineral oil
1
NBT
1
Sodium citrate
1
Biopolymers
1
Glutamic acid
1
Dexrazoxane
1
CFS
1
AZT
1
Rituximab
1
Vitamin K
1
Sodium citrate
1
TTC
1
Theophylline
1
THA
1
APD
1
Ouabain
1
Glycerol
1
Fructose
1
PCB
1
ADM
1
Mutagen
1
Pegademase bovine
1
Ethanol
1
Acyclovir
1
Cellulose acetate
1
ABC
1
ascorbate
1
Ranitidine
1
Adenosine deaminase
1
more...
Enzyme
asparaginase
2695
glutaminase
193
asparagine synthetase
103
thrombin
35
P-glycoprotein
29
APC
29
trypsin
26
urease
25
urease
25
glutamine synthetase
24
CD10
22
lactate dehydrogenase
20
peroxidase
20
thromboplastin
19
deaminase
19
glutamate dehydrogenase
15
focal adhesion kinase
15
glutamate dehydrogenase
15
acid phosphatase
15
glutamate dehydrogenase
14
lipase
13
alkaline phosphatase
12
aspartate aminotransferase
12
ACS
10
alanine aminotransferase
9
arginase
9
aspartase
9
L-asparagine synthetase
8
ERK
8
cellulase
8
BMT
8
catalase
8
protein kinase
8
aspartylglucosaminidase
7
mitogen-activated protein kinase
7
chymotrypsin
7
caspase-3
7
topoisomerase
7
carboxypeptidase Y
7
glutamate synthase
7
glutamate synthase
6
adenosine deaminase
6
adenosine deaminase
6
tyrosinase
6
lipoprotein lipase
6
histidase
6
glutamate synthase
6
invertase
5
beta-galactosidase
5
cathepsin B
5
lysozyme
5
arginine deiminase
5
gamma-glutamyl transpeptidase
5
RNA polymerase
5
ricin
5
topoisomerase
5
beta-secretase
5
superoxide dismutase
5
PARP
4
thiopurine methyltransferase
4
glutamic dehydrogenase
4
luciferase
4
TdT
4
phospholipase C
4
creatine kinase
4
RNase
4
RNase
4
glucose oxidase
4
alcohol dehydrogenase
4
methylenetetrahydrofolate reductase
3
hyaluronidase
3
beta-glucosidase
3
pyruvate kinase
3
MDP
3
TAT
3
asparaginyl-tRNA synthetase
3
cholinesterase
3
ribonuclease
3
ACE
3
glutathione S-transferase
3
more...
Compound
asparagine
606
glutamine
198
Dec
169
Clin
138
PEG
134
Asp
134
nitrogen
132
DNA
116
ammonia
107
aspartic acid
104
PEG
102
glucose
88
acrylamide
78
ammonium
77
aspartic acid
63
aspartic acid
59
aspartic acid
59
sodium
57
sulfate
47
glutamate
47
water
43
SDS
41
urea
39
threonine
38
oxygen
37
Methotrexate
37
Ara-C
35
MTT
30
His
29
Ara-C
27
phosphate
26
alanine
26
arginine
26
serine
25
calcium
25
glutamic acid
24
lysine
24
methionine
23
proline
21
tyrosine
20
cysteine
19
MTX
19
hydrogen
18
Glutamine
18
NH2
17
VP-16
17
salt
17
Adriamycin
17
ATP
16
ethanol
16
zinc
16
DEAE
16
potassium
15
Vincristine
15
Optimal
14
leucine
12
norvaline
12
BCR
12
galactose
12
VM-26
12
CTX
12
norvaline
12
Phe
11
ABL
11
TEL
11
nickel
11
EDTA
11
EDTA
11
ACS
10
pyrimidine
10
acetate
10
Gly
10
ACS
10
glycerol
10
pyrimidine
10
6-Mercaptopurine
10
tryptophan
9
tryptophan
9
phenol
9
nitrate
9
more...