Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.1 (asparaginase)
 2,695 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
L-asparaginase 13.5
L-glutaminase 12.7
HLA-DRB1 protein 12.5
CAGLP 11.9
PTPRK protein 11.9
ASPG 11.7
ASRGL1 11.5
asparagine synthetase 11.4
SMILE 11.3
ASP1 10.9
AS-B 10.8
TCFL5 10.7
CLEC11A 10.5
glycosylasparaginase 10.5
KCNN1 10.2
glutaminase 10.1
GALNT10 10.1
HCC1 9.9
NSE1 9.9
PTPRK 9.9
Glutaminase 9.6
ASP 9.6
LGMN 9.5
MAN1A1 9.5
CCDC88C 9.5
aspartylglucosaminidase 9.5
ASNS 9.4
opioid receptor mu 9.4
CITED4 9.4
asp 9.4
Aspartylglycosaminuria 9.3
SOX12 9.1
TRDV2 9.1
NXF2 9.1
CEP72 9.1
A. nidulans) 9.1
MAP3K12 9.0
TBXAS1 9.0
BCL2L13 8.9
SPEF2 8.9
AGT1 8.9
LMF1 8.9
PR domain zinc finger protein 1 8.8
GLUR1 8.8
HSP70B' 8.8
CNOT3 8.6
Pancreatic elastase 8.6
MYBBP1A 8.6
ubiquitin-conjugating enzyme E2C 8.6
PCDH9 8.5
upstream stimulatory factor 2 8.5
HLA protein 8.4
ribosomal protein P2 8.4
histidase 8.3
POMP 8.2
activating transcription factor 5 8.2
PYCR1 8.1
asparaginyl-tRNA synthetase 8.1
Napsin-A 8.1
PEG1 8.1
GLS1 8.1
KRS 8.0
F8A 8.0
CRASH 8.0
ALL 8.0
aspartylglycosaminuria 7.9
Antithrombin-III 7.9
RSPO2 7.9
secreted frizzled-related protein 4 7.9
HRG 7.8
IL16 7.8
MRPP2 7.8
HACE1 7.8
SBP1 7.8
SmF 7.7
histidine ammonia-lyase 7.7
major vault protein 7.7
VDP 7.6
SLC1A3 7.6
RagB 7.6
GCN2 7.6
GluR-A 7.5
CD7 antigen 7.5
TXR 7.5
PTGDR 7.5
MRG 7.5
NUDT15 7.4
NFATC2 7.4
EIF4E 7.4
RSPO3 7.4
TSN 7.4
POG 7.4
ULK2 7.4
Immunoglobulin heavy chain 7.3
AFF1 7.3
p53 up-regulated modulator of apoptosis 7.3
SBP2 7.3
SHOC2 7.3
fatty acid ethyl ester synthase 7.3
cysteinyl leukotriene receptor 1 7.3
MTA phosphorylase 7.3
WS3 7.3
runt-related transcription factor 1 7.3
TFDP3 7.2
TEL 7.2
extracellular matrix protein 1 7.2
Lysophospholipase 7.2
GPIHBP1 7.2
GDL 7.2
Rpn4 7.1
TRIM24 7.1
B1 protein 7.0
TLX3 7.0
thiopurine S-methyltransferase 7.0
BLU 7.0
9p22 7.0
antithrombin 7.0
SLC19A2 7.0
DNA-directed RNA polymerase 7.0
UTF1 7.0
LBR 6.9
ara 6.9
thymidine kinase 2 6.9
MOLT 6.8
CLASP 6.8
IGFBP7 6.8
APOC2 6.8
IL4R 6.8
ST19 6.7
alkaline phosphodiesterase I 6.7
MTX 6.7
initiation factor 2 6.7
VHR 6.7
interferon alpha 2b 6.7
CD7 6.6
BTG1 6.6
Cystathionine gamma-lyase 6.6
AML1 6.6
SLC1A5 6.6
TNC 6.6
P43 6.6
MUM-1 6.6
Antithrombin III 6.5
plasma protein C 6.5
telomerase catalytic subunit 6.5
pancreatitis-associated protein 6.5
antithrombin III 6.5
R-spondin 6.4
HRI 6.4
LGALS3 6.4
soluble liver antigen 6.4
HLA-DQA1 6.4
SSF 6.4
ALOX5 6.4
activating transcription factor 4 6.4
LAL 6.4
GPR56 6.4
dihydrodipicolinate synthase 6.3
CTSB 6.3
argininosuccinate synthase 6.3
more...
Disease
Myelemia 12.5
FAB L1 10.9
childhood lymphoblastic lymphoma 10.7
untreated adult acute lymphoblastic leukemia 10.7
Central nervous system leukemia 10.5
CAMR 10.4
NK-cell leukemia 10.3
Superior sagittal sinus thrombosis 10.2
Childhood Leukemia 10.2
relapsed childhood ALL 10.0
adult ALL 10.0
Extranodal NK/T-cell lymphoma, nasal type 10.0
childhood ANLL 9.9
childhood ALL 9.3
c-ALL 9.2
acute lymphoblastic leukemia 8.9
hypofibrinogenemia 8.8
FAB M0 8.8
T/NK-cell lymphoma 8.7
childhood NHL 8.6
lymphadenosis 8.5
Reversible posterior leukoencephalopathy syndrome 8.4
acute undifferentiated leukemia 8.2
FAB M1 8.1
external hemorrhoids 8.0
Farber 8.0
mouse leukemia P388 7.9
Localized disease 7.9
T-cell lymphoma 7.8
Hemorrhagic pancreatitis 7.7
disaccharidase deficiency 7.7
Toxicosis 7.7
Aspartylglucosaminuria 7.7
T-cell acute lymphoblastic leukemia 7.6
Neutropenic enterocolitis 7.6
Lymphoblastic lymphoma 7.5
JHS 7.4
lymphosarcoma 7.4
MRD 7.3
B-ALL 7.3
FAB M4 7.2
FAB M2 7.2
progressive bulbar palsy 7.1
Philadelphia chromosome positive 7.1
berry aneurysm 7.1
lymphoblastic leukemia 7.0
Medulla 7.0
Activated protein C resistance 7.0
cerebral thrombosis 7.0
acute nonlymphocytic leukemia 6.7
KRS 6.7
jejunitis 6.7
prolymphocytic leukemia 6.6
Cerebral venous thrombosis 6.6
T-cell lymphomas 6.5
acute leukemia 6.5
Hypereosinophilic syndrome 6.4
mouse leukemia L1210 6.3
pancreatitis 6.3
Hemorrhagic cystitis 6.3
aggressive lymphoma 6.2
extranodal lymphoma 6.2
lymphoblastoma 6.2
Leukemia 6.2
minimal residual disease 6.2
pediatric AML 6.1
Cerebral venous sinus thrombosis 6.1
Fibrosarcoma 6.1
myelosuppression 6.1
hyperchloremia 6.1
leukemia 6.1
hyperproteinemia 6.0
Peripheral T-cell lymphoma 6.0
hyperviscosity syndrome 6.0
tumor lysis syndrome 6.0
Pneumocystis carinii infection 5.9
AOA 5.9
islet cell carcinoma 5.8
lymphoid neoplasm 5.8
coagulopathy 5.8
childhood cancer 5.7
Ototoxicity 5.7
lymphoma 5.7
afibrinogenemia 5.6
angioimmunoblastic T-cell lymphoma 5.6
hypochloremia 5.6
acute pancreatitis 5.6
drug hypersensitivity 5.6
dysfibrinogenemia 5.5
posttransfusion hepatitis 5.5
adult AML 5.4
physical dependence 5.4
IGS 5.4
disseminated intravascular coagulation 5.4
NHL 5.4
histiocytic lymphoma 5.4
Thrombophilia 5.4
Interstitial fibrosis 5.4
superficial thrombophlebitis 5.4
anaphylaxis 5.4
leukoencephalopathy 5.3
histiocytic lymphoma 5.3
acute monocytic leukemia 5.3
secondary AML 5.3
blood cancer 5.2
hyperbilirubinemia 5.2
Thrombus 5.2
blast crisis 5.2
CLE 5.2
non-Hodgkin's lymphoma 5.2
CLE 5.2
testicular carcinoma 5.2
leptomeningeal metastases 5.2
serum sickness 5.1
pseudotuberculosis 5.0
chronic rhinitis 5.0
pancreatic cyst 5.0
parotitis 5.0
SIADH 5.0
CEM 5.0
chronic leukemia 4.9
veno-occlusive disease 4.9
Sezary syndrome 4.9
acute myeloid leukemia 4.9
Arthus reaction 4.8
Acute graft-versus-host disease 4.8
ADA deficiency 4.8
ABL 4.8
RBS 4.8
hypopyon 4.8
LGL leukemia 4.8
hepatic veno-occlusive disease 4.7
Epstein 4.7
pericardial disease 4.7
benign nevi 4.6
sicca syndrome 4.6
diplegia 4.6
Li-Fraumeni syndrome 4.6
neutropenia 4.5
hemangiosarcoma 4.5
protein deficiency 4.5
diabetic ketoacidosis 4.4
orbital cellulitis 4.4
Burkitt's lymphoma 4.4
AGS 4.4
biliary tract disease 4.4
lymphocytosis 4.3
EL4 4.3
hyperglycemia 4.3
paralytic ileus 4.3
PLG 4.3
anaplastic large cell lymphoma 4.3
Chronic GVHD 4.3
recurrent ovarian cancer 4.3
vitamin C deficiency 4.2
hematologic malignancies 4.2
KNO 4.2
Beard 4.2
B-cell lymphomas 4.2
LIN 4.1
more...
Symptom
hypoproteinemia 5.7
anal pain 5.6
ketonuria 5.4
autodigestion 5.2
hepatosplenomegaly 4.7
ataxic gait 4.4
nasal congestion 4.4
polydipsia 4.0
polyuria 4.0
agitation 3.8
starvation 3.6
splenomegaly 3.6
nausea 3.5
blurred vision 3.5
vomiting 3.5
epigastric pain 3.4
hepatomegaly 3.3
decreased appetite 3.3
pallor 3.2
Sedation 3.1
nasal discharge 3.1
nausea and vomiting 3.1
anorexia 2.9
hip pain 2.7
lethargy 2.6
abdominal pain 2.6
acute abdominal pain 2.6
hemiplegia 2.6
fever of unknown origin 2.5
chills 2.5
skin irritation 2.5
flank pain 2.4
seizures 2.3
tachypnea 2.2
asthenia 2.2
paraparesis 2.1
tremor 1.9
headache 1.8
diarrhea 1.8
arthralgia 1.7
cerebellar ataxia 1.7
Ill 1.7
erythema 1.4
wheezing 1.3
paresthesia 1.3
weakness 1.1
flushing 0.9
sleepiness 0.9
myalgia 0.8
dyspnea 0.8
fatigue 0.7
acidity 0.6
ataxia 0.6
dystonia 0.5
syncope 0.4
analgesia 0.3
dizziness 0.3
low back pain 0.2
constipation 0.2
insomnia 0.2
discomfort 0.1
back pain -0.0
discomfort -0.0
overweight -0.2
exhaustion -0.2
Welt -0.4
chest pain -0.5
hypothermia -0.6
respiratory distress -0.7
cough -1.0
pain -1.1
collapse -1.3
Drug
Pegaspargase 13.2
Asparaginase 13.1
Oncaspar 13.0
L-Asparaginase 12.8
Pegademase bovine 11.9
ARA-C 8.3
Mercaptopurine 8.2
Teniposide 8.0
Clofarabine 7.4
TEL 7.4
Idarubicin 6.8
Hydroxyethylstarch 6.8
Sodium citrate 6.7
Sodium citrate 6.7
Mineral oil 6.6
Antithrombin III 6.5
AraC 6.3
Dexrazoxane 6.1
RSM 6.1
Dextrose 5.9
Etoposide 5.7
Maltose 5.7
Cellulose acetate 5.5
Prednisolone 5.3
Asn 5.3
Taxotere 5.2
VCR 5.2
Bayer 5.2
Prednisone 5.1
Adriamycin 5.0
Bortezomib 5.0
Vinorelbine 4.8
beta-Galactosidase 4.8
ISP 4.6
Glutamic acid 4.5
MgSO4 4.5
VCR 4.5
CFS 4.2
BLM 4.1
Adenosine deaminase 4.1
TAT 3.9
CTX 3.8
G-CSF 3.8
Docetaxel 3.7
APD 3.7
THA 3.7
Growth hormone 3.6
Growth hormone 3.5
PFA 3.5
ADR 3.5
Acyclovir 3.5
Lactose 3.4
Serum albumin 3.3
NBT 3.2
Vitamin K 3.1
Ranitidine 2.9
NH3 2.7
Bevacizumab 2.7
lactose 2.7
TTC 2.7
Fructose 2.6
Theophylline 2.5
MDS 2.4
Glycerol 2.4
Ouabain 2.2
ROC 2.2
ETS 2.2
AZT 2.1
DNase I 2.1
Rituximab 2.0
lysine 2.0
Gel 2.0
AZT 2.0
ADM 1.9
Taxol 1.9
citric acid 1.8
niacin 1.6
CSF 1.6
THF 1.5
PCB 1.5
Leaf 1.1
CTX 1.1
CTX 1.0
Mutagen 1.0
PTH 0.8
NADH 0.7
Biopolymers 0.5
ABC 0.4
nitroglycerin 0.4
ROS 0.3
Ethanol 0.3
Monit -0.6
Nephron -0.6
caffeine -0.9
ascorbate -1.0
IFN-gamma -1.3
Dial -1.4
Dermatol -2.2
Enzyme
asparaginase 13.5
EC 2.6.1.14 13.1
EC 3.5.1.38 12.5
peptidoglutaminase 12.1
L-asparagine synthetase 11.7
asparagine synthetase 11.2
omega-amidase 10.3
glutaminase 10.2
peptidase E 9.7
aspartylglucosaminidase 9.5
glutaminase II 9.4
aspartase 9.0
L-aspartate oxidase 8.8
asparaginyl-tRNA synthetase 8.6
cancer procoagulant 8.6
leucine aminotransferase 8.4
histidase 8.2
chloromuconate cycloisomerase 8.2
desulfinase 8.0
desulfhydrase 7.9
glutamic dehydrogenase 7.7
phosphoenolpyruvate synthase 7.5
D-serine dehydratase 7.3
arabinose isomerase 7.2
arylsulfate sulfotransferase 7.2
tyrosine phenol-lyase 7.1
glutamyl-tRNA synthetase 7.0
leucine dehydrogenase 6.9
1-aminocyclopropane-1-carboxylate deaminase 6.7
glutamate synthase 6.7
carbamate kinase 6.6
amidophosphoribosyltransferase 6.6
allantoinase 6.6
glutamate synthase 6.5
glutamate synthase 6.5
legumain 6.5
proline oxidase 6.4
thiopurine methyltransferase 6.4
anthocyanidin synthase 6.4
flavonol synthase 6.3
dihydrodipicolinate synthase 6.3
penicillin acylase 6.3
methioninase 6.2
arginine deiminase 6.1
sarcosine oxidase 6.1
tryptophanase 6.1
beta-secretase 6.1
carboxypeptidase G2 6.0
carboxypeptidase Y 6.0
adenylosuccinate lyase 6.0
tyrosine decarboxylase 5.9
serine hydroxymethyltransferase 5.9
acetylesterase 5.8
glutamine synthetase 5.8
stilbene synthase 5.8
methylthioadenosine phosphorylase 5.7
stilbene synthase 5.7
aspartyl-tRNA synthetase 5.7
tannase 5.5
deaminase 5.5
alanine dehydrogenase 5.4
urease 5.3
glutamate dehydrogenase 5.3
glutamate dehydrogenase 5.3
urease 5.3
pectate lyase 5.3
glutamate dehydrogenase 5.2
inulinase 5.2
BMT 5.2
FPS 5.1
neuropathy target esterase 5.1
inulinase 5.0
alanine aminopeptidase 5.0
sucrose synthase 4.9
nitrilase 4.9
aspartokinase 4.9
xylose isomerase 4.9
phospholipase A1 4.9
lysine decarboxylase 4.9
arginase 4.8
phenol oxidase 4.8
tryptophan 2,3-dioxygenase 4.8
CD10 4.7
P-glycoprotein 4.7
TdT 4.6
alpha-L-fucosidase 4.6
alpha-L-fucosidase 4.5
cystathionine gamma-lyase 4.5
arginine decarboxylase 4.5
aromatic L-amino acid decarboxylase 4.5
APC 4.4
uricase 4.3
arginine decarboxylase 4.3
ricin 4.2
mu-calpain 4.1
argininosuccinate synthetase 4.1
thromboplastin 4.1
methylenetetrahydrofolate reductase 4.1
methylenetetrahydrofolate reductase 4.1
ornithine aminotransferase 4.0
DAT 4.0
isoamylase 4.0
alpha-L-fucosidase 4.0
PNGase F 4.0
lactic acid dehydrogenase 3.9
TAT 3.9
cathepsin B 3.8
PST 3.8
cellulase 3.8
phosphoglucose isomerase 3.8
adenosine deaminase 3.8
acid phosphatase 3.8
adenosine deaminase 3.8
MDP 3.7
LasR 3.7
Pla 3.7
nitrite reductase 3.7
nitrite reductase 3.6
nitrite reductase 3.6
beta-glucosidase 3.6
thrombin 3.6
invertase 3.6
thymidine phosphorylase 3.5
NADH dehydrogenase 3.5
sorbitol dehydrogenase 3.5
beta-glucosidase 3.4
lipoprotein lipase 3.3
CD13 3.3
histidine kinase 3.3
arylsulfatase 3.3
RNase T1 3.3
xanthine dehydrogenase 3.3
alpha-ketoglutarate dehydrogenase 3.2
TPP 3.2
RNase P 3.1
glucose oxidase 3.1
proteinase K 3.1
phenylalanine hydroxylase 3.1
topoisomerase 3.1
gamma-glutamylcysteine synthetase 3.0
lipase 3.0
TPP 3.0
lactate dehydrogenase 3.0
transpeptidase 3.0
histidine decarboxylase 3.0
tyrosinase 3.0
malate dehydrogenase 2.9
chymotrypsin 2.9
trypsin 2.9
leucine aminopeptidase 2.9
granzyme B 2.8
DTA 2.8
alpha-galactosidase 2.8
paraoxonase 2.8
ornithine transcarbamylase 2.8
pyruvate kinase 2.8
succinic dehydrogenase 2.8
prostate-specific membrane antigen 2.7
aspartate aminotransferase 2.7
nitrogenase 2.7
more...
Compound
DONV 13.5
D-Asparagine 12.9
2-methyl-2-propenyl 11.2
2-methyl-2-propenyl 10.9
3-cyanoalanine 10.2
Sulfosalicylic acid 10.1
3-hydroxyaspartic acid 9.7
3-hydroxyaspartic acid 9.7
3-hydroxyaspartic acid 9.7
3-hydroxyaspartic acid 9.7
3-hydroxyaspartic acid 9.5
3-hydroxyaspartic acid 9.4
alpha-ketoglutaramate 9.3
asparagine 9.2
MEDA 9.1
L-Gulonolactone 8.9
M 14 8.7
Harringtonine 8.4
Harringtonine 8.4
Harringtonine 8.4
4-methylbenzenesulfonamide 8.4
norvaline 8.4
Blasticidin S 8.3
norvaline 8.3
6-Mercaptopurine 8.2
Mechlorethamine 8.1
A-14 8.0
Acivicin 7.7
MOPA 7.7
MOPA 7.7
Ara-C 7.7
Ara-C 7.6
Vincristine 7.6
3-(methylthio)propanal 7.5
VM-26 7.4
TEL 7.4
3-hydroxyaspartic acid 7.3
N-ethylurea 7.2
CFN 7.2
Daunorubicin 7.2
allantoate 7.1
ASN 7.1
Tizanidine 7.0
Homoharringtonine 7.0
PCMB 7.0
PCMB 7.0
PCMB 7.0
RUB 6.9
PCMB 6.9
Glutamine 6.7
MTX 6.7
aspartic acid 6.6
glutamine 6.5
Methotrexate 6.4
Tropisetron 6.3
Sudan Black B 6.3
DON 6.2
Latrunculin A 6.1
Ifosfamide 6.1
aspartic acid 6.1
aspartic acid 6.0
Daunomycin 6.0
Gliotoxin 6.0
aspartic acid 6.0
VP-16 6.0
Dansyl 6.0
2-methyl-2,4-pentanediol 5.9
keto-gamma 5.9
2,5-dimethylfuran 5.9
ASE 5.9
Fumarate 5.8
Actinomycin 5.8
norleucine 5.8
acrylamide 5.8
Vinca 5.7
5-formyltetrahydrofolate 5.7
CCNU 5.7
Maltose 5.6
isonicotinamide 5.6
2-oxobutyrate 5.6
1,3-propanediamine 5.6
Acridine Orange 5.6
Acridine Orange 5.6
Acridine Orange 5.6
TEPA 5.5
Asp 5.5
norleucine 5.5
Diol 5.4
Prednisolone 5.3
5-Aza-2'-deoxycytidine 5.3
AIB 5.3
2-oxobutyrate 5.3
ACNU 5.2
FDP 5.2
DIC 5.2
MME 5.1
Luminol 5.0
oxalacetate 5.0
PEG 4.9
MIA 4.9
MCE 4.9
Propidium iodide 4.9
Topotecan 4.9
Epirubicin 4.9
PHE 4.9
DLA 4.9
Ornithine 4.8
ammonia 4.8
PEG 4.8
folinic acid 4.8
DFS 4.7
Fibrinogen 4.7
BCNU 4.7
APTES 4.7
Malachite Green 4.6
Adriamycin 4.6
Octreotide 4.6
phthalaldehyde 4.6
NFS 4.5
Amide 4.5
m-AMSA 4.5
ABL 4.5
BCR 4.5
Prednisone 4.4
N-hydroxysuccinimide ester 4.4
BLM 4.4
Topotecan 4.4
propionaldehyde 4.3
Vinblastine 4.2
Mitoxantrone 4.2
Mitoxantrone 4.2
2-mercaptoethanol 4.1
Dithiothreitol 4.1
Thioflavin T 4.1
glutamic acid 4.1
TMEDA 4.1
HAP 4.1
LIN 4.0
DAT 4.0
succinic acid 4.0
succinic acid 4.0
succinic acid 4.0
succinic acid 4.0
isonicotinic acid 4.0
Inulin 4.0
Sorbitol 3.9
Levamisole 3.9
Vitamin D3 3.9
Dithiothreitol 3.9
LCR 3.9
L-leucine 3.9
Gemcitabine 3.9
IPA 3.8
ammonium 3.8
Gemcitabine 3.8
IPA 3.8
IPA 3.8
NTA 3.8
IPA 3.8
CTX 3.8
more...