Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.5.1.1 (asparaginase)
 2,695 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
L-asparaginase 1504
glutaminase 167
Sep 163
ALL 114
asparagine synthetase 101
PEG 92
Mol 69
fibrinogen 64
Pseudomonas 60
ASP 59
antithrombin 56
lymphoid 48
asp 45
antithrombin III 41
SDS 39
insulin 37
thrombin 36
non-Hodgkin's lymphoma 36
CHOP 30
L-glutaminase 30
SMILE 30
P-glycoprotein 29
plasminogen 29
threonine 28
protein C 25
She 25
prothrombin 24
glutamine synthetase 24
Pol 22
ara 21
CD10 20
mTOR 20
HLA 20
polypeptide 20
TEL 19
protein S 19
MTX 19
amylase 18
CD56 18
albumin 17
thromboplastin 16
ATP 16
hemoglobin 16
Gen 15
acid phosphatase 15
LDH 15
MOLT 15
lactate dehydrogenase 15
CD4 14
Glutaminase 14
serum albumin 14
CD19 14
AML 13
glutamate dehydrogenase 13
CD7 13
IgE 13
BCR 12
alkaline phosphatase 12
lipase 12
NMR 12
FAB 12
p53 12
peroxidase 12
fused 11
HLA-DR 11
MLL 11
esterase 11
ABL 11
CBT 11
AML1 11
Bcl-2 10
SOD 10
VIII 10
CD34 10
MRI 10
myeloperoxidase 10
ACS 10
endoplasmic reticulum 10
CD2 9
glycosylasparaginase 9
glycoprotein 9
initiation factor 2 8
phosphatase 8
A-I 8
caspase-3 8
aspartate aminotransferase 8
granulocyte colony-stimulating factor 8
natural killer cell 8
collagen 8
STAT 8
tyrosine kinase 8
RUNX1 8
CD33 8
CD20 8
factor VIII 7
factor V 7
gut 7
NHL 7
glucosidase 7
GCN2 7
catalase 7
dimeric 7
CD5 7
DIC 7
CD38 7
granulocyte 7
E.coli 7
G-CSF 6
CD8 6
lipoprotein lipase 6
TCR 6
PLA 6
von Willebrand factor 6
aspartylglucosaminidase 6
growth hormone 6
THP 6
osteosarcoma 6
MDR1 6
DBA 6
tRNA 6
CSF 6
adenosine deaminase 6
cytokine 6
interferon 6
histone 6
nodal 5
peptidase 5
ASP1 5
plasminogen activator inhibitor 5
CR1 5
cathepsin B 5
NOD 5
thymus 5
white cell 5
ferritin 5
ESI 5
reductase 5
CD30 5
LL) 5
MIA 5
TCA 5
histidase 5
lysozyme 5
human leukocyte antigen 5
HLA-DRB1 5
AMP 5
somatostatin 5
EFS 4
cytochrome c 4
alanine aminotransferase 4
RPMI 4
fibronectin 4
tissue factor 4
creatine kinase 4
PHA 4
factor VII 4
IgA 4
Hop 4
protease inhibitor 4
ATF4 4
more...
Disease
acute lymphoblastic leukemia 892
leukemia 525
cancer 505
lymphoma 311
tumor 209
childhood ALL 136
pancreatitis 106
Leukemia 94
T-cell lymphoma 90
acute myeloid leukemia 86
acute leukemia 69
adult ALL 62
Epstein 52
hyperglycemia 50
lymphoblastic leukemia 43
non-Hodgkin's lymphoma 43
acute pancreatitis 43
T-cell acute lymphoblastic leukemia 42
SDS 39
coagulopathy 36
neutropenia 34
Hodgkin's disease 34
myelosuppression 34
thrombocytopenia 32
disseminated intravascular coagulation 31
diabetes 30
minimal residual disease 30
sepsis 28
anaphylaxis 28
sepsis 25
lymphosarcoma 23
chronic myeloid leukemia 23
B-ALL 22
encephalopathy 21
T-cell lymphomas 21
hypofibrinogenemia 20
childhood cancer 19
lymphadenopathy 19
obesity 17
hyperlipidemia 17
tumor growth 16
multiple myeloma 15
carcinoma 14
Farber 14
acute nonlymphocytic leukemia 13
hematologic malignancies 13
pneumonia 13
depression 13
ovarian cancer 13
hypercalcemia 12
stroke 12
hyperbilirubinemia 12
ABL 11
Burkitt's lymphoma 11
CEM 11
peripheral neuropathy 11
NK-cell leukemia 10
MCF 10
anemia 10
fits 9
graft-versus-host disease 9
cold 9
adenocarcinoma 9
hypertension 9
pulmonary embolism 9
Mycobacterium 9
glucose intolerance 8
coma 8
leukoencephalopathy 8
infectious diseases 8
SCID 8
chronic lymphocytic leukemia 8
blast crisis 8
Childhood Leukemia 8
acute promyelocytic leukemia 8
tumor progression 8
sarcoma 8
osteosarcoma 7
deep vein thrombosis 7
chronic lymphocytic leukemia 7
SEM 7
metastases 7
tumorigenesis 7
pseudotuberculosis 7
Thrombus 7
pancytopenia 7
hepatitis 7
NHL 7
hemiparesis 7
breast cancer 7
B-cell lymphomas 6
Yersinia 6
DBA 6
Klebsiella 6
stomatitis 6
West 6
MRD 6
melanoma 6
colorectal cancer 6
hepatocellular carcinoma 6
rare disease 6
physical dependence 6
myocardial infarction 6
lymphocytosis 6
B-cell lymphoma 6
addiction 6
myelodysplastic syndrome 6
leukopenia 6
heart failure 5
NOD 5
Proteus 5
drug hypersensitivity 5
mole 5
cardiomyopathy 5
neuropathy 5
Down syndrome 5
HIV 5
diabetic ketoacidosis 5
vasculitis 5
aggression 5
glioma 5
tuberculosis 5
FAB L1 5
Best 5
acute undifferentiated leukemia 5
solid tumor 5
lymphoproliferative disorders 5
histiocytic lymphoma 5
myeloid leukemia 5
fungal infection 5
hypoglycemia 5
rash 5
Posterior 4
mole 4
ischemia 4
PHA 4
c-ALL 4
aggressive lymphoma 4
neuroblastoma 4
liver disease 4
AGS 4
agranulocytosis 4
Extranodal NK/T-cell lymphoma, nasal type 4
epilepsy 4
lung cancer 4
residual disease 4
leukemogenesis 4
dehydration 4
myocarditis 4
myeloproliferative disorders 4
hypercholesterolemia 4
tumor lysis syndrome 4
cerebral thrombosis 4
aplastic anemia 4
pruritus 3
leishmaniasis 3
brain atrophy 3
varicella 3
Philadelphia chromosome positive 3
proteinuria 3
more...
Symptom
seizures 34
vomiting 30
starvation 26
nausea 23
diarrhea 17
headache 17
abdominal pain 16
agitation 14
splenomegaly 10
pain 10
hepatosplenomegaly 10
anorexia 9
nausea and vomiting 7
fatigue 7
weakness 7
tremor 6
hepatomegaly 5
hypoproteinemia 5
dyspnea 4
polyuria 4
Ill 3
polydipsia 3
epigastric pain 3
erythema 3
lethargy 3
analgesia 3
chills 2
discomfort 2
discomfort 2
ataxia 2
nasal congestion 2
acidity 2
blurred vision 2
pallor 2
ketonuria 2
sleepiness 2
overweight 2
hemiplegia 2
arthralgia 2
cerebellar ataxia 1
fever of unknown origin 1
flank pain 1
exhaustion 1
wheezing 1
flushing 1
decreased appetite 1
Sedation 1
asthenia 1
insomnia 1
chest pain 1
back pain 1
respiratory distress 1
ataxic gait 1
paraparesis 1
Welt 1
constipation 1
cough 1
autodigestion 1
acute abdominal pain 1
low back pain 1
dizziness 1
myalgia 1
nasal discharge 1
collapse 1
syncope 1
dystonia 1
hypothermia 1
tachypnea 1
hip pain 1
paresthesia 1
skin irritation 1
anal pain 1
Drug
Asparaginase 194
L-Asparaginase 103
Asn 39
Pegaspargase 29
lysine 20
Adriamycin 13
CTX 12
TEL 11
lactose 9
CSF 8
AraC 7
Oncaspar 7
ARA-C 6
G-CSF 6
Bayer 5
Dermatol 5
Gel 5
Prednisolone 5
Etoposide 5
Bortezomib 4
Antithrombin III 4
Leaf 4
NH3 4
VCR 3
DNase I 3
ROC 3
NADH 3
TAT 3
Prednisone 3
Growth hormone 3
Growth hormone 3
citric acid 3
MgSO4 3
Docetaxel 2
THF 2
Dextrose 2
RSM 2
ROS 2
ADR 2
Clofarabine 2
Teniposide 2
Idarubicin 2
VCR 2
Monit 2
Maltose 2
Taxotere 2
BLM 2
Nephron 1
ETS 1
Serum albumin 1
Dial 1
Mineral oil 1
NBT 1
Sodium citrate 1
Biopolymers 1
Glutamic acid 1
Dexrazoxane 1
CFS 1
AZT 1
CTX 1
Vitamin K 1
Vinorelbine 1
Theophylline 1
Sodium citrate 1
TTC 1
CTX 1
THA 1
Ouabain 1
PTH 1
Fructose 1
AZT 1
Glycerol 1
nitroglycerin 1
Pegademase bovine 1
Rituximab 1
Ethanol 1
IFN-gamma 1
Hydroxyethylstarch 1
PCB 1
ADM 1
Mutagen 1
Acyclovir 1
Cellulose acetate 1
ABC 1
ascorbate 1
caffeine 1
APD 1
Ranitidine 1
Adenosine deaminase 1
Lactose 1
Taxol 1
Mercaptopurine 1
MDS 1
beta-Galactosidase 1
Bevacizumab 1
PFA 1
ISP 1
niacin 1
Enzyme
asparaginase 2695
glutaminase 193
asparagine synthetase 103
thrombin 35
APC 29
P-glycoprotein 29
trypsin 26
urease 25
urease 25
glutamine synthetase 24
CD10 22
lactate dehydrogenase 20
peroxidase 20
deaminase 19
thromboplastin 19
focal adhesion kinase 15
acid phosphatase 15
glutamate dehydrogenase 15
glutamate dehydrogenase 15
glutamate dehydrogenase 14
lipase 13
alkaline phosphatase 12
aspartate aminotransferase 12
ACS 10
aspartase 9
alanine aminotransferase 9
arginase 9
cellulase 8
ERK 8
protein kinase 8
BMT 8
catalase 8
L-asparagine synthetase 8
aspartylglucosaminidase 7
topoisomerase 7
carboxypeptidase Y 7
chymotrypsin 7
caspase-3 7
mitogen-activated protein kinase 7
glutamate synthase 7
adenosine deaminase 6
glutamate synthase 6
glutamate synthase 6
histidase 6
lipoprotein lipase 6
adenosine deaminase 6
tyrosinase 6
cathepsin B 5
arginine deiminase 5
superoxide dismutase 5
beta-secretase 5
ricin 5
topoisomerase 5
beta-galactosidase 5
invertase 5
gamma-glutamyl transpeptidase 5
lysozyme 5
RNA polymerase 5
glutamic dehydrogenase 4
TdT 4
RNase 4
RNase 4
creatine kinase 4
phospholipase C 4
PARP 4
thiopurine methyltransferase 4
glucose oxidase 4
luciferase 4
alcohol dehydrogenase 4
legumain 3
neuropathy target esterase 3
acetylcholinesterase 3
MDP 3
cancer procoagulant 3
pyruvate kinase 3
asparaginyl-tRNA synthetase 3
glutathione S-transferase 3
beta-glucosidase 3
proteinase K 3
serine hydroxymethyltransferase 3
ribonuclease 3
CD13 3
cholinesterase 3
ACE 3
urokinase-type plasminogen activator 3
malate dehydrogenase 3
ribonuclease 3
diaphorase 3
peptidoglutaminase 3
EC 2.6.1.14 3
hyaluronidase 3
proteasome 3
beta-glucosidase 3
TAT 3
methylenetetrahydrofolate reductase 3
methylenetetrahydrofolate reductase 3
CAD 2
penicillin acylase 2
phosphoglucose isomerase 2
aldehyde dehydrogenase 2
glutamyl-tRNA synthetase 2
omega-amidase 2
aldehyde dehydrogenase 2
alpha-amylase 2
alanine aminopeptidase 2
aldehyde dehydrogenase 2
aldehyde dehydrogenase 2
nitrate reductase 2
aldehyde dehydrogenase 2
reverse transcriptase 2
nitrogenase 2
ATPase 2
tryptophan 2,3-dioxygenase 2
AMP-activated protein kinase 2
nitrate reductase 2
nitrate reductase 2
MEK 2
nitrite reductase 2
plasmin 2
histidine kinase 2
uricase 2
nitrite reductase 2
nitrite reductase 2
NADH dehydrogenase 2
beta-lactamase 2
granzyme B 2
nitrate reductase 2
complex I 2
laccase 2
tryptophanase 2
nitrate reductase 2
phenol oxidase 2
hyaluronidase 2
DAT 2
PNGase F 2
AST 2
calcineurin 2
sucrose synthase 2
proline oxidase 2
pectate lyase 2
nitrate reductase 2
beta-glucuronidase 2
DNA polymerase 2
NOS 2
aspartyl-tRNA synthetase 1
chondroitinase 1
CAD 1
nitrilase 1
methylthioadenosine phosphorylase 1
AMPK 1
elastase 1
cathepsin L 1
TPP 1
carboxypeptidase G2 1
protein kinase C 1
papain 1
stilbene synthase 1
leucine dehydrogenase 1
1-aminocyclopropane-1-carboxylate deaminase 1
thymidine phosphorylase 1
more...
Compound
asparagine 606
glutamine 198
Dec 169
Clin 138
Asp 134
PEG 134
nitrogen 132
DNA 116
ammonia 107
aspartic acid 104
PEG 102
glucose 88
acrylamide 78
ammonium 77
aspartic acid 63
aspartic acid 59
aspartic acid 59
sodium 57
glutamate 47
sulfate 47
water 43
SDS 41
urea 39
threonine 38
oxygen 37
Methotrexate 37
Ara-C 35
MTT 30
His 29
Ara-C 27
alanine 26
arginine 26
phosphate 26
serine 25
calcium 25
glutamic acid 24
lysine 24
methionine 23
proline 21
tyrosine 20
cysteine 19
MTX 19
Glutamine 18
hydrogen 18
NH2 17
Adriamycin 17
VP-16 17
salt 17
zinc 16
ethanol 16
DEAE 16
ATP 16
Vincristine 15
potassium 15
Optimal 14
VM-26 12
leucine 12
BCR 12
norvaline 12
CTX 12
galactose 12
norvaline 12
Phe 11
nickel 11
TEL 11
EDTA 11
EDTA 11
ABL 11
acetate 10
pyrimidine 10
6-Mercaptopurine 10
ACS 10
glycerol 10
Gly 10
ACS 10
pyrimidine 10
tryptophan 9
tryptophan 9
tryptophan 9
nitrate 9
phenol 9
HCl 9
tryptophan 9
iron 8
DIC 8
bromide 8
copper 7
guanidine 7
2-oxoglutarate 7
acetone 7
sodium chloride 7
cAMP 7
DBA 6
hydroxylamine 6
ASN 6
creatinine 6
THP 6
hydroxylamine 6
MIA 6
THP 6
DBA 6
Fibrinogen 6
Daunorubicin 6
2-mercaptoethanol 6
DBA 6
Ile 6
ADR 6
iodine 6
cadmium 5
BCG 5
isoleucine 5
DSM 5
BLM 5
AMP 5
Prednisolone 5
Dexamethasone 5
Pac 5
BCNU 5
Triton X-100 5
DON 5
isoleucine 5
TCA 5
Tris 5
Tris 5
Heparin 5
boron 4
norleucine 4
CCNU 4
folinic acid 4
Mg2+ 4
norleucine 4
retinoic acid 4
ADP 4
xylose 4
succinic acid 4
ornithine 4
ornithine 4
methanol 4
TEM 4
Curcumin 4
5-FU 4
GlcNAc 4
ornithine 4
ACTH 4
ornithine 4
ornithine 4
Insulin 4
valine 4
vinyl 4
acetic acid 3
cobalt 3
succinic acid 3
Isoproterenol 3
CO2 3
manganese 3
succinic acid 3
Prednisone 3
succinic acid 3
NADH 3
L-leucine 3
more...