Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.5.1.1 (
asparaginase
)
2,695
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
L-asparaginase
(140,000 units) infused into the hepatic artery resulted in a remission from disabling hypoglycaemia for nine months in a man with islet cell carcinoma of the pancreas and hepatic metastases. The tumour produced insulin and
gastrin
with resulting hypoglycaemia and recurrent peptic ulceration which were unresponsive to other drugs. Following
L-asparaginase
there was a fall in both plasma and insulin and
gastrin
.
...
PMID:Prolonged control of hypoglycaemia by L-asparaginase in islet cell carcinoma producing insulin and gastrin. 17 39
