Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.25.1 (proteasome)
28,817 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein proteasome 0.907 ubiquitin 0.132 MCP 0.055 proteasome inhibitor 0.040 Proteasome 0.027 chymotrypsin-like 0.010 Ubiquitin 0.010 ubiquitin ligase 0.006 E3 ubiquitin ligase 0.006 LMP7 0.006 Rpn10 0.004 LMP2 0.003 F-box protein 0.002 COP9 0.002 SCF 0.002 atrogin-1 0.002 Rpn13 0.002 PA28alpha 0.002 p97 0.002 Rpn11 0.002 Cdc48 0.002 Rpn1 0.002 PSMB5 0.002 Skp1 0.002 endoplasmic reticulum 0.002 USP14 0.002 cullin 0.002 deubiquitinating enzyme 0.002 membrane cofactor protein 0.001 MECL-1 0.001 Rpn4 0.001 VCP 0.001 MuRF1 0.001 UCHL5 0.001 ubiquitin-conjugating enzyme 0.001 Dsk2 0.001 PA200 0.001 POMP 0.001 PA28beta 0.001 Rpn2 0.001 CD46 0.001 PA28gamma 0.001 ubiquitin-like protein 0.001 CHIP 0.001 Atrogin-1 0.001 UPS 0.001 MHC class I 0.001 POH1 0.001 PSMA7 0.001 Rpn5 0.001 calpain 0.001 ubiquitin-protein ligase 0.001 MuRF 0.001 Ecm29 0.001 UCH37 0.001 PSMD4 0.001 muscle protein 0.001 Skp2 0.001 Mol 0.001 HRD1 0.001 E2 ubiquitin-conjugating enzyme 0.001 PSMC1 0.001 AAA 0.001 SUG1 0.001 p53 0.001 parkin 0.001 Rpn3 0.001 peptidase 0.001 p62 0.001 PSMA3 0.001 SKP1 0.001 PSMB4 0.001 UBB 0.001 PSMA1 0.001 E6AP 0.001 MSS1 0.001 PSMB7 0.001 antizyme 0.000 ubiquitin-specific protease 0.000 NEDD8 0.000 more...

Disease multiple myeloma 0.002 muscular atrophy 0.001 cancer 0.001 AAA 0.001 Parkinson's disease 0.000 tumor 0.000 mantle cell lymphoma 0.000 abdominal aortic aneurysm 0.000 Huntington's disease 0.000 Hippel 0.000 Alzheimer's disease 0.000 amyotrophic lateral sclerosis 0.000 tumorigenesis 0.000 APC 0.000 tumor growth 0.000 IBMPFD 0.000 aHUS 0.000 breast cancer 0.000 hematologic malignancies 0.000 leukemia 0.000 neuroblastoma 0.000 CPAF 0.000 wasting 0.000 retinoblastoma 0.000 SDS 0.000 PML 0.000 hepatocellular carcinoma 0.000 permeability; increased 0.000 Autologous graft versus host disease 0.000 prostate cancer 0.000 PARK2 0.000 virus infection 0.000 MCF 0.000 carcinogenesis 0.000 tumor progression 0.000 acute promyelocytic leukemia 0.000 macroglobulinemia 0.000 Machado-Joseph disease 0.000 Acute calcific periarthritis 0.000 Diarrhea-negative HUS 0.000 PARK6 0.000 colon cancer 0.000 parkinsonism 0.000 Cancer cachexia 0.000 PARK1 0.000 peripheral neuropathy 0.000 Atopic allergy 0.000 Miles-Carpenter syndrome 0.000 lymphoma 0.000 lung cancer 0.000 melanoma 0.000 DIP 0.000 hemolytic uremic syndrome 0.000 cytomegalovirus 0.000 cystic fibrosis 0.000 SMAX2 0.000 HIV 0.000 coenurosis 0.000 PARK7 0.000 myopathy 0.000 ARTS 0.000 Giant axonal neuropathy 0.000 MIP 0.000 Complex II deficiency 0.000 FGD3 0.000 glioblastoma 0.000 ATM 0.000 dementia 0.000 HRD 0.000 Blocking 0.000 SPAR 0.000 ovarian cancer 0.000 Delayed delivery 0.000 PARK4 0.000 relapsed cutaneous T-cell lymphoma 0.000 CEP 0.000 HSP 0.000 pancreatic cancer 0.000 SBMA 0.000 Spinocerebellar ataxia 0.000 more...

Symptom cachexia 0.000 starvation 0.000 ataxia 0.000 CNS symptom 0.000 Diaphragmatic weakness 0.000 weakness 0.000 Localized pain 0.000 collapse 0.000 autodigestion 0.000 Ear swelling 0.000 Organ failure 0.000 anorexia 0.000 Cold intolerance 0.000 bradykinesia 0.000 Hyperextension 0.000 Positive and Negative Symptoms 0.000 tremor 0.000 fatigue 0.000 male subfertility 0.000 facial droop 0.000 pain 0.000 memory loss 0.000 agitation 0.000 Tenderness 0.000 exhaustion 0.000 scaly skin 0.000 cerebellar ataxia 0.000 Spastic 0.000 acute stress 0.000 diarrhea 0.000 dystonia 0.000 loss of balance 0.000 Halo 0.000 Opposition 0.000 hyperoxia 0.000 hand pain 0.000 functional recovery 0.000 hypotonia 0.000 acidity 0.000 ACHE 0.000 bone pain 0.000 joint stiffness 0.000 incoordination 0.000 prostatism 0.000 decreased appetite 0.000 asthenia 0.000 seizures 0.000 erythema 0.000 Psychiatric symptoms 0.000 respiratory distress 0.000 intention tremor 0.000 vomiting 0.000 nausea 0.000 skin damage 0.000 general problem 0.000 mastalgia 0.000 irregular bleeding 0.000 Scratch 0.000 arthralgia 0.000 Spots 0.000 heel pain 0.000 rundown 0.000 Decreased activity 0.000 Anoxia 0.000 tingling 0.000 adenitis 0.000 numbness 0.000 nausea and vomiting 0.000 bitter taste 0.000 limb pain 0.000 hypothermia 0.000 myalgia 0.000 HSA 0.000 twitching 0.000 dysesthesia 0.000 emaciation 0.000 microbial colonization 0.000 thinning 0.000 dyspnea 0.000 Neuropathic pain 0.000 more...

Drug Bortezomib 0.007 Parkin 0.000 Parkin 0.000 lysine 0.000 AMC 0.000 Methionine Sulfoxide 0.000 ROS 0.000 IFN-gamma 0.000 Lenalidomide 0.000 Montirelin 0.000 Kifunensine 0.000 Ammonium phosphate 0.000 Dibasic calcium phosphate 0.000 Thalomid 0.000 Tanespimycin 0.000 DFP 0.000 3,4-Dichloroisocoumarin 0.000 CXD 0.000 Arsenic trioxide 0.000 Indisulam 0.000 Apomorphine hydrochloride 0.000 Vorinostat 0.000 Revlimid 0.000 Romidepsin 0.000 ATV 0.000 Toad venom 0.000 NVP 0.000 Fulvestrant 0.000 Flavopiridol 0.000 Bindarit 0.000 Resovist 0.000 8-Azaguanine 0.000 CA-074 0.000 Radicicol 0.000 Asn 0.000 K201 0.000 Auranofin 0.000 Tolfenamic acid 0.000 TAK 0.000 MAP 0.000 SPP 0.000 Troglitazone 0.000 Etoposide 0.000 Peridinin 0.000 Onconase 0.000 Alanine 0.000 CoCl2 0.000 CoCl2 0.000 Sorafenib 0.000 Nitric Oxide 0.000 Eculizumab 0.000 Sinefungin 0.000 Rituximab 0.000 CSF 0.000 IL-2 0.000 BH4 0.000 Kenyan 0.000 Primperan 0.000 Gel 0.000 Imatinib 0.000 Rasagiline 0.000 Angiotensin II 0.000 BoNT/A 0.000 Tipifarnib 0.000 ETS 0.000 GVG 0.000 Gefitinib 0.000 EPL 0.000 Dexrazoxane 0.000 RFP 0.000 GEO 0.000 PFT 0.000 Vesnarinone 0.000 TAT 0.000 Ciglitazone 0.000 Alimta 0.000 G-CSF 0.000 IFN-beta 0.000 ICI 0.000 Casodex 0.000 more...

Enzyme proteasome 1.000 ubiquitin-protein ligase 0.002 isopeptidase 0.001 ATPase 0.000 proteasome ATPase 0.000 protein kinase 0.000 mitogen-activated protein kinase 0.000 IKK 0.000 trypsin 0.000 caspase-3 0.000 cdc2 0.000 m-calpain 0.000 cathepsin B 0.000 APC 0.000 ornithine decarboxylase 0.000 chymotrypsin 0.000 spermosin 0.000 caspase-8 0.000 elastase 0.000 ERK 0.000 subtilisin 0.000 ClpP 0.000 MEK 0.000 arginyltransferase 0.000 pseudolysin 0.000 TPP 0.000 prolyl hydroxylase 0.000 PARP 0.000 GSK 0.000 mannosidase I 0.000 calcineurin 0.000 PNGase F 0.000 insulin-degrading enzyme 0.000 caspase-9 0.000 luciferase 0.000 p100 0.000 focal adhesion kinase 0.000 bleomycin hydrolase 0.000 AMP-activated protein kinase 0.000 mu-calpain 0.000 ubiquityl-calmodulin synthetase 0.000 chaperonin 0.000 serralysin 0.000 cathepsin D 0.000 thimet oligopeptidase 0.000 RNA polymerase 0.000 nucleotidase 0.000 protein kinase C 0.000 blasticidin-S deaminase 0.000 Ht-b 0.000 phosphatidylinositol 3-kinase 0.000 glutathione S-transferase 0.000 AMPK 0.000 protein phosphatase 2A 0.000 ACC oxidase 0.000 AMPK 0.000 carboxypeptidase Y 0.000 MIP 0.000 cathepsin L 0.000 CFI 0.000 prozyme 0.000 topoisomerase 0.000 calpain 3 0.000 PHD 0.000 topoisomerase 0.000 NS protease 0.000 Omi/HtrA2 0.000 ACC synthase 0.000 carboxypeptidase S 0.000 O-GlcNAc transferase 0.000 thermomycolase 0.000 caspase-1 0.000 separase 0.000 methionine sulfoxide reductase 0.000 polo-like kinase 1 0.000 peptidoglutaminase 0.000 glucosamine kinase 0.000 nepenthesin 0.000 3C protease 0.000 aspartyl aminopeptidase 0.000 more...

Compound MCP 0.044 Ubiquitin 0.005 CHIP 0.001 AAA 0.001 TAP 0.000 ATP 0.000 lysine 0.000 DNA 0.000 serine 0.000 threonine 0.000 leucine 0.000 tyrosine 0.000 NOXA 0.000 oxygen 0.000 cysteine 0.000 Cbl 0.000 alanine 0.000 Geldanamycin 0.000 Dec 0.000 Ethylene 0.000 E-64 0.000 aldehyde 0.000 SDS 0.000 PMSF 0.000 aldehyde 0.000 C8H6O2 0.000 C8H6O2 0.000 Erioflorin 0.000 2-methylmalonamide 0.000 Tris-p-nitrophenyl phosphate 0.000 RUB 0.000 celastrol 0.000 arginine 0.000 Thiostrepton 0.000 MEK 0.000 Calpeptin 0.000 UPP 0.000 C22H30O5 0.000 C30H22O4 0.000 TNF 0.000 MDA 0.000 PAN 0.000 TMC 0.000 2-Nitrodiphenylamine 0.000 Antimycin A1 0.000 2-Nitrodiphenylamine 0.000 calcium 0.000 Serine 0.000 Celastrol 0.000 Ile 0.000 COS 0.000 MCA 0.000 PYR 0.000 MCA 0.000 Gambogic acid 0.000 glucose 0.000 3-methylhistidine 0.000 3-methylcyclopentanone 0.000 proline 0.000 2-nonenal 0.000 CUE 0.000 4-chloro-2-methylphenol 0.000 boron 0.000 C10H10O2 0.000 C7H4N2O2 0.000 Sanggenon C 0.000 C7H4N2O2 0.000 C7H4N2O2 0.000 Phe 0.000 Nelfinavir 0.000 Epigallocatechin gallate 0.000 glutamine 0.000 retinoic acid 0.000 OLN 0.000 IAA 0.000 methionine 0.000 IAA 0.000 N-acetylcysteine 0.000 Asp 0.000 N-Acetylimidazole 0.000 more...

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