Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.25.1 (proteasome)
 28,817 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein
proteasome endopeptidase complex 10.1
DNM1L protein 10.1
Ubiquitin carboxyl-terminal hydrolase 47 10.1
ZNF297 10.1
proteasome 10.1
R3H domain containing 1 10.1
UBE2J2 10.1
C20orf23 10.1
MRPL22 10.1
EIF3S12 10.1
OAZ1 protein 10.1
CCDC58 10.1
ZNF709 10.1
F-box protein 16 10.1
NFE2-related factor 1 10.1
Ubiquitin associated protein 2 10.1
Kelch-like protein 5 10.1
proteasomal ATPase-associated factor 1 10.1
UBXD4 10.1
HCV core-binding protein 10.1
GSPT1 protein 10.1
p44.5 10.1
mHag HB-1 10.1
SNF2 histone linker PHD RING helicase 10.1
Histone H2B type 1-H 10.1
manic fringe homolog 10.1
KIAA0675 10.1
RING finger protein 220 10.1
NOC4L 10.1
vacuolar protein sorting 28 homolog 10.1
Ubiquitin A-52 residue ribosomal protein fusion product 1 10.1
Rpn5 10.1
MCP 10.1
anaphase-promoting complex subunit 5 10.1
Praja 1 10.1
HECT domain containing 3 10.1
Ubiquitin-conjugating enzyme E2 J2 10.1
RAP140 10.1
MXD1 protein 10.1
TMEM109 10.1
kelch repeat and BTB (POZ) domain containing 2 10.1
CYP51A1 protein 10.1
USP25 protein 10.1
ubiquitin specific protease 25 10.1
UBCH6 10.1
RXRA protein 10.1
SEC13-like 1 isoform 10.1
ring finger protein 19 10.1
ubiquitin conjugation factor E4 A 10.1
ZNF711 protein 10.1
ring finger protein 121 10.1
CSN7B 10.1
NIP30 10.1
proteasome subunit C9 10.1
PROS-30 10.1
MLF2 protein 10.1
stromal membrane-associated protein 1 10.1
C20orf31 10.1
DRIP2 10.1
ubiquitin specific peptidase 11 10.1
FBL7 10.1
zinc finger protein 644 10.1
CXX1B 10.1
Nin1p 10.1
mutant cardiac myosin-binding protein C 10.1
F-box only protein 15 10.1
LRRC41 10.1
RAPGEF2 protein 10.1
mitochondrial translational release factor 1-like 10.1
Rpn3 10.1
MAP4K3 protein 10.1
UIP5 10.1
H2AFO 10.1
proteasome 26S subunit, ATPase, 1 10.1
UBR7 protein 10.1
proteasome beta-2 10.1
ubiquitin carboxyl-terminal hydrolase L5 10.1
ZFAND1 10.1
ARHA protein 10.1
p40.5 10.1
more...
Disease
Autologous graft versus host disease 10.1
permeability; increased 10.1
Diarrhea-negative HUS 9.1
Acute calcific periarthritis 9.1
Atopic allergy 8.5
Miles-Carpenter syndrome 8.5
SMAX2 8.1
IBMPFD 7.9
Complex II deficiency 7.8
aHUS 7.7
relapsed cutaneous T-cell lymphoma 7.5
Delayed delivery 7.5
SLE arthritis 7.3
type B thymoma 7.3
FGD3 7.3
CPAF 7.3
PARK4 7.1
BBS11 7.1
Malignant insulinoma 7.1
CISS1 7.1
Bouchard's nodes 7.1
PARK1 7.0
Granular corneal dystrophy 6.9
FENIB 6.8
cerebral cancer 6.8
rapid reinstatement 6.8
PARK10 6.7
NIDDM2 6.7
XLG2 6.7
Juvenile Parkinsonism 6.7
Congenital Myasthenic Syndromes 6.7
PARK6 6.6
SPAR 6.6
bone marrow cancer 6.6
Disuse atrophy 6.6
Giant axonal neuropathy 6.5
ALS8 6.5
EDA-ID 6.5
late onset disorder 6.4
Equine grass sickness 6.4
ARTS 6.4
AAA 6.4
coenurosis 6.3
X-linked alpha-thalassemia/mental retardation syndrome 6.3
LGMD2H 6.3
Adenomatosis 6.3
Yoshida Sarcoma 6.3
Lymphocystis disease 6.3
AGS2 6.2
Viral Hemorrhagic Septicemia 6.2
SCA13 6.2
CMT1C 6.2
IDDM8 6.0
PARK3 6.0
HRD 6.0
vLINCL 5.9
MDC1A 5.9
SBMA 5.9
HLS1 5.9
Congenital muscular dystrophy 5.8
Critical illness myopathy 5.8
muscular atrophy 5.8
Cancer cachexia 5.8
PARK2 5.7
MDC1C 5.7
ZD1 5.7
Axonal Neuropathy 5.7
Macular corneal dystrophy 5.7
stage IV renal cell carcinoma 5.7
PARK7 5.6
Oculopharyngeal muscular dystrophy 5.6
FXTAS 5.6
mantle cell lymphoma 5.6
AIDS-related malignancies 5.5
FIH 5.5
MMMT 5.5
SCA14 5.5
Hepatic impairment 5.5
Staring 5.4
EIM 5.4
more...
Symptom
CNS symptom 7.8
Diaphragmatic weakness 5.9
Localized pain 5.4
cachexia 5.1
Organ failure 4.1
Ear swelling 4.1
Cold intolerance 4.0
autodigestion 3.8
Hyperextension 3.8
starvation 3.5
Positive and Negative Symptoms 3.5
facial droop 3.1
male subfertility 3.1
ataxia 2.7
scaly skin 2.7
Spastic 2.6
Tenderness 2.6
Opposition 2.4
hand pain 2.4
loss of balance 2.3
Halo 2.3
ACHE 2.2
bradykinesia 2.2
prostatism 1.9
Psychiatric symptoms 1.8
intention tremor 1.7
joint stiffness 1.6
mastalgia 1.5
irregular bleeding 1.5
decreased appetite 1.5
Scratch 1.5
memory loss 1.5
general problem 1.4
incoordination 1.3
cerebellar ataxia 1.3
Spots 1.3
weakness 1.3
heel pain 1.2
anorexia 1.2
rundown 1.1
skin damage 1.1
acute stress 1.1
bone pain 1.1
asthenia 1.1
Decreased activity 1.0
Anoxia 1.0
adenitis 1.0
collapse 0.9
hyperoxia 0.9
tingling 0.8
hypotonia 0.8
limb pain 0.7
dystonia 0.7
bitter taste 0.7
tremor 0.6
agitation 0.6
exhaustion 0.5
functional recovery 0.3
dysesthesia 0.2
HSA 0.1
acidity 0.1
twitching 0.1
arthralgia 0.1
numbness 0.1
emaciation 0.1
microbial colonization 0.1
erythema 0.0
fatigue -0.1
myalgia -0.2
nausea and vomiting -0.3
respiratory distress -0.3
Neuropathic pain -0.4
anosmia -0.5
nausea -0.5
torticollis -0.5
diarrhea -0.7
vomiting -0.7
oliguria -0.7
sneezing -0.8
hypothermia -0.8
more...
Drug
Methionine Sulfoxide 9.1
Bortezomib 8.7
Montirelin 7.8
Ammonium phosphate 7.5
Dibasic calcium phosphate 7.3
Kifunensine 7.1
Thalomid 6.9
3,4-Dichloroisocoumarin 6.7
Tanespimycin 6.6
Parkin 6.5
Parkin 6.5
CXD 6.4
Indisulam 6.3
Apomorphine hydrochloride 6.3
Toad venom 6.0
AMC 5.7
Bindarit 5.6
Revlimid 5.6
8-Azaguanine 5.4
Romidepsin 5.3
K201 5.1
Radicicol 5.0
Lenalidomide 5.0
Resovist 4.9
CA-074 4.9
Flavopiridol 4.7
Tolfenamic acid 4.7
Peridinin 4.7
Vorinostat 4.6
ATV 4.6
Fulvestrant 4.5
Onconase 4.4
Sinefungin 4.3
DFP 4.3
Primperan 4.1
Auranofin 4.0
Tipifarnib 4.0
Arsenic trioxide 3.9
NVP 3.9
SPP 3.9
Vesnarinone 3.8
Ciglitazone 3.8
Rasagiline 3.8
Alimta 3.8
GVG 3.8
EPL 3.7
Dexrazoxane 3.7
Eculizumab 3.7
Troglitazone 3.6
Casodex 3.5
lysine 3.5
Belimumab 3.5
BLyS 3.4
Pramipexole 3.4
Nexavar 3.4
Pramipexole 3.4
TAK 3.3
Fluphenazine 3.2
Thioridazine 3.2
PFT 3.2
Pepstatin 3.2
Celebrex 3.2
Etoposide 3.1
Rhubarb 3.1
Hyperforin 3.0
Vandetanib 3.0
CoCl2 3.0
CoCl2 3.0
ROS 2.9
Trabectedin 2.9
BoNT/A 2.9
Rebamipide 2.9
Sorafenib 2.9
NLF 2.8
Emodin 2.8
Tianeptine 2.8
Panitumumab 2.8
3-Methyladenine 2.7
DEL 2.7
BH4 2.7
more...
Enzyme
proteasome 10.1
proteasome ATPase 9.7
spermosin 8.9
Ht-b 8.5
blasticidin-S deaminase 8.5
ubiquityl-calmodulin synthetase 8.1
ubiquitin-protein ligase 8.0
isopeptidase 7.6
arginyltransferase 7.5
thermomycolase 7.3
pseudolysin 7.2
glucosamine kinase 7.1
peptidoglutaminase 7.1
NS protease 7.1
succinyl-diaminopimelate desuccinylase 6.8
serralysin 6.8
bleomycin hydrolase 6.8
oligopeptidase A 6.7
prozyme 6.7
phosphoenolpyruvate-protein phosphotransferase 6.7
carboxypeptidase 1 6.5
nepenthesin 6.4
aspartyl aminopeptidase 6.4
retinoid isomerase 6.3
mannosidase I 6.3
m-calpain 6.2
carboxypeptidase S 6.2
thimet oligopeptidase 6.0
Aeromonas proteolytica aminopeptidase 5.9
tail-specific protease 5.9
PcpB 5.9
lecithin-retinol acyltransferase 5.9
ketopantoate hydroxymethyltransferase 5.8
nicotinamide adenine dinucleotide glycohydrolase 5.8
thermitase 5.8
vibriolysin 5.7
protease La 5.7
calpain 10 5.7
ClpP 5.7
3-hydroxyisobutyryl-CoA hydrolase 5.6
ACC oxidase 5.5
zeta-carotene desaturase 5.5
insulin-degrading enzyme 5.4
methionine sulfoxide reductase 5.4
AAO3 5.4
nicotinic acid mononucleotide adenylyltransferase 5.3
IKK 5.3
Omi/HtrA2 5.3
mu-calpain 5.3
p100 5.2
calpain 3 5.2
calpain 3 5.2
separase 5.2
ACC synthase 5.2
conjugase 5.1
nardilysin 5.1
oligopeptidase B 5.1
TPP 5.1
neurosin 5.1
stringent factor 5.0
tripeptidyl peptidase 5.0
peptidyl-tRNA hydrolase 5.0
O-GlcNAc transferase 5.0
levansucrase 4.9
nucleotidase 4.9
prolyl hydroxylase 4.9
PNGase F 4.9
caspase-4 4.9
3C protease 4.9
carboxypeptidase II 4.9
cucumisin 4.9
phosphoethanolamine N-methyltransferase 4.9
dihydroxyacetone kinase 4.8
branched-chain alpha-keto acid dehydrogenase 4.8
CFI 4.8
cathepsin B 4.8
caspase-4 4.8
amylo-1,6-glucosidase 4.8
galactosylhydroxylysyl glucosyltransferase 4.7
caffeoyl-CoA O-methyltransferase 4.7
more...
Compound
C8H6O2 10.1
C8H6O2 10.1
Erioflorin 10.1
2-methylmalonamide 10.1
Tris-p-nitrophenyl phosphate 10.1
MCP 9.8
C22H30O5 9.1
C30H22O4 9.1
2-Nitrodiphenylamine 8.5
Antimycin A1 8.5
2-Nitrodiphenylamine 8.5
C7H4N2O2 8.1
C7H4N2O2 8.1
Sanggenon C 8.1
C10H10O2 8.1
C7H4N2O2 8.1
Ubiquitin 8.0
Robinin 7.8
C7H4N2O2 7.8
N-Acetylimidazole 7.8
Robinin 7.8
C7H4N2O2 7.8
Caffeoyl-CoA 7.8
C7H4N2O2 7.5
Dibenzalacetone 7.5
3-methylcyclopentanone 7.4
CHIP 7.4
4-methylpentanamide 7.3
C5H8O 7.1
Flumidin 7.1
Thiostrepton 7.1
Calpeptin 7.0
4-chloro-2-methylphenol 7.0
Calotropin 6.9
Cucurbitacin D 6.9
RUB 6.8
Ethyl linoleate 6.8
Calotropin 6.8
UPP 6.7
Physalin B 6.7
Calotropin 6.7
Triptonide 6.7
Ebelactone B 6.7
Geldanamycin 6.6
Thiolutin 6.5
N-Nitrosodiphenylamine 6.5
Caprin 6.5
NOXA 6.5
AAA 6.4
Pristimerin 6.4
Pristimerin 6.4
Pristimerin 6.4
Pristimerin 6.4
TAP 6.3
Propargylamine 6.3
LLY 6.3
DTBHQ 6.3
Gambogic acid 6.2
OLN 6.2
2,6-piperazinedione 6.2
imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 6.2
Ammonium dihydrogen phosphate 6.2
LGE2 6.2
Dipin 6.2
Ribostamycin 6.2
Z-Arg-Arg-NHMec 6.2
Monocalcium phosphate 6.2
Lariciresinol 6.1
4-hydrazinobenzoic acid 6.1
Wedelolactone 6.1
Apomorphine hydrochloride 6.0
Phthalide 6.0
C15H24 6.0
Ailanthone 6.0
[6]-Shogaol 6.0
CUE 6.0
4-hydrazinobenzoic acid 5.9
Resibufogenin 5.9
Deoxyelephantopin 5.9
Nelfinavir 5.9
more...