Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.25.1 (proteasome)
28,817 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
proteasome 0.907
ubiquitin 0.132
MCP 0.055
proteasome inhibitor 0.040
Proteasome 0.027
chymotrypsin-like 0.010
Ubiquitin 0.010
ubiquitin ligase 0.006
E3 ubiquitin ligase 0.006
LMP7 0.006
Rpn10 0.004
LMP2 0.003
F-box protein 0.002
COP9 0.002
SCF 0.002
atrogin-1 0.002
Rpn13 0.002
PA28alpha 0.002
p97 0.002
Rpn11 0.002
Cdc48 0.002
Rpn1 0.002
PSMB5 0.002
Skp1 0.002
endoplasmic reticulum 0.002
USP14 0.002
cullin 0.002
deubiquitinating enzyme 0.002
membrane cofactor protein 0.001
MECL-1 0.001
Rpn4 0.001
VCP 0.001
MuRF1 0.001
UCHL5 0.001
ubiquitin-conjugating enzyme 0.001
Dsk2 0.001
PA200 0.001
POMP 0.001
PA28beta 0.001
Rpn2 0.001
more...
Disease
multiple myeloma 0.002
muscular atrophy 0.001
cancer 0.001
AAA 0.001
Parkinson's disease 0.000
tumor 0.000
mantle cell lymphoma 0.000
abdominal aortic aneurysm 0.000
Huntington's disease 0.000
Hippel 0.000
Alzheimer's disease 0.000
amyotrophic lateral sclerosis 0.000
tumorigenesis 0.000
APC 0.000
tumor growth 0.000
IBMPFD 0.000
aHUS 0.000
breast cancer 0.000
hematologic malignancies 0.000
leukemia 0.000
neuroblastoma 0.000
CPAF 0.000
wasting 0.000
retinoblastoma 0.000
SDS 0.000
PML 0.000
hepatocellular carcinoma 0.000
Autologous graft versus host disease 0.000
permeability; increased 0.000
prostate cancer 0.000
PARK2 0.000
virus infection 0.000
MCF 0.000
carcinogenesis 0.000
tumor progression 0.000
acute promyelocytic leukemia 0.000
macroglobulinemia 0.000
Machado-Joseph disease 0.000
Acute calcific periarthritis 0.000
Diarrhea-negative HUS 0.000
more...
Symptom
cachexia 0.000
starvation 0.000
ataxia 0.000
CNS symptom 0.000
Diaphragmatic weakness 0.000
weakness 0.000
Localized pain 0.000
collapse 0.000
autodigestion 0.000
Ear swelling 0.000
Organ failure 0.000
anorexia 0.000
Cold intolerance 0.000
bradykinesia 0.000
Hyperextension 0.000
Positive and Negative Symptoms 0.000
tremor 0.000
fatigue 0.000
male subfertility 0.000
facial droop 0.000
pain 0.000
memory loss 0.000
agitation 0.000
Tenderness 0.000
exhaustion 0.000
scaly skin 0.000
cerebellar ataxia 0.000
Spastic 0.000
acute stress 0.000
diarrhea 0.000
dystonia 0.000
loss of balance 0.000
Halo 0.000
Opposition 0.000
hyperoxia 0.000
hand pain 0.000
functional recovery 0.000
hypotonia 0.000
acidity 0.000
ACHE 0.000
more...
Drug
Bortezomib 0.007
Parkin 0.000
Parkin 0.000
lysine 0.000
AMC 0.000
Methionine Sulfoxide 0.000
ROS 0.000
IFN-gamma 0.000
Lenalidomide 0.000
Montirelin 0.000
Ammonium phosphate 0.000
Kifunensine 0.000
Dibasic calcium phosphate 0.000
Thalomid 0.000
Tanespimycin 0.000
DFP 0.000
3,4-Dichloroisocoumarin 0.000
CXD 0.000
Arsenic trioxide 0.000
Indisulam 0.000
Apomorphine hydrochloride 0.000
Vorinostat 0.000
Revlimid 0.000
Romidepsin 0.000
ATV 0.000
Toad venom 0.000
NVP 0.000
Fulvestrant 0.000
Flavopiridol 0.000
Bindarit 0.000
Resovist 0.000
8-Azaguanine 0.000
CA-074 0.000
Radicicol 0.000
Asn 0.000
K201 0.000
Auranofin 0.000
Tolfenamic acid 0.000
TAK 0.000
MAP 0.000
more...
Enzyme
proteasome 1.000
ubiquitin-protein ligase 0.002
isopeptidase 0.001
ATPase 0.000
proteasome ATPase 0.000
protein kinase 0.000
mitogen-activated protein kinase 0.000
IKK 0.000
trypsin 0.000
caspase-3 0.000
cdc2 0.000
m-calpain 0.000
cathepsin B 0.000
APC 0.000
ornithine decarboxylase 0.000
chymotrypsin 0.000
spermosin 0.000
caspase-8 0.000
elastase 0.000
ERK 0.000
subtilisin 0.000
ClpP 0.000
MEK 0.000
arginyltransferase 0.000
pseudolysin 0.000
TPP 0.000
prolyl hydroxylase 0.000
PARP 0.000
GSK 0.000
mannosidase I 0.000
calcineurin 0.000
PNGase F 0.000
insulin-degrading enzyme 0.000
caspase-9 0.000
luciferase 0.000
p100 0.000
focal adhesion kinase 0.000
bleomycin hydrolase 0.000
AMP-activated protein kinase 0.000
mu-calpain 0.000
more...
Compound
MCP 0.044
Ubiquitin 0.005
CHIP 0.001
AAA 0.001
TAP 0.000
ATP 0.000
lysine 0.000
DNA 0.000
serine 0.000
threonine 0.000
leucine 0.000
tyrosine 0.000
NOXA 0.000
oxygen 0.000
cysteine 0.000
Cbl 0.000
alanine 0.000
Geldanamycin 0.000
Dec 0.000
Ethylene 0.000
E-64 0.000
aldehyde 0.000
SDS 0.000
PMSF 0.000
aldehyde 0.000
C8H6O2 0.000
Erioflorin 0.000
2-methylmalonamide 0.000
Tris-p-nitrophenyl phosphate 0.000
C8H6O2 0.000
RUB 0.000
celastrol 0.000
arginine 0.000
Thiostrepton 0.000
MEK 0.000
Calpeptin 0.000
UPP 0.000
C30H22O4 0.000
C22H30O5 0.000
TNF 0.000
more...