Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.25.1 (proteasome)
 28,817 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein
Ubiquitin-conjugating enzyme E2 J2 10.1
ubiquitin conjugation factor E4 A 10.1
SEC13-like 1 isoform 10.1
OAZ1 protein 10.1
ZNF297 10.1
p40.5 10.1
F-box protein 16 10.1
USP25 protein 10.1
NIP30 10.1
ring finger protein 121 10.1
proteasome 10.1
LRRC41 10.1
proteasome endopeptidase complex 10.1
DNM1L protein 10.1
HCV core-binding protein 10.1
RAPGEF2 protein 10.1
F-box only protein 15 10.1
proteasome 26S subunit, ATPase, 1 10.1
Kelch-like protein 5 10.1
Ubiquitin A-52 residue ribosomal protein fusion product 1 10.1
p44.5 10.1
SNF2 histone linker PHD RING helicase 10.1
ubiquitin specific protease 25 10.1
Praja 1 10.1
KIAA0675 10.1
MRPL22 10.1
UBCH6 10.1
EIF3S12 10.1
CCDC58 10.1
PROS-30 10.1
kelch repeat and BTB (POZ) domain containing 2 10.1
proteasomal ATPase-associated factor 1 10.1
stromal membrane-associated protein 1 10.1
MXD1 protein 10.1
C20orf31 10.1
Rpn5 10.1
UBE2J2 10.1
Ubiquitin carboxyl-terminal hydrolase 47 10.1
GSPT1 protein 10.1
Histone H2B type 1-H 10.1
more...
Disease
permeability; increased 10.1
Autologous graft versus host disease 10.1
Acute calcific periarthritis 9.1
Diarrhea-negative HUS 9.1
Miles-Carpenter syndrome 8.5
Atopic allergy 8.5
SMAX2 8.1
IBMPFD 7.9
Complex II deficiency 7.8
aHUS 7.7
relapsed cutaneous T-cell lymphoma 7.5
Delayed delivery 7.5
CPAF 7.3
SLE arthritis 7.3
FGD3 7.3
type B thymoma 7.3
Malignant insulinoma 7.1
Bouchard's nodes 7.1
CISS1 7.1
PARK4 7.1
BBS11 7.1
PARK1 7.0
Granular corneal dystrophy 6.9
cerebral cancer 6.8
FENIB 6.8
rapid reinstatement 6.8
XLG2 6.7
Juvenile Parkinsonism 6.7
PARK10 6.7
NIDDM2 6.7
Congenital Myasthenic Syndromes 6.7
PARK6 6.6
SPAR 6.6
bone marrow cancer 6.6
Disuse atrophy 6.6
EDA-ID 6.5
Giant axonal neuropathy 6.5
ALS8 6.5
Equine grass sickness 6.4
late onset disorder 6.4
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Symptom
CNS symptom 7.8
Diaphragmatic weakness 5.9
Localized pain 5.4
cachexia 5.1
Ear swelling 4.1
Organ failure 4.1
Cold intolerance 4.0
autodigestion 3.8
Hyperextension 3.8
starvation 3.5
Positive and Negative Symptoms 3.5
facial droop 3.1
male subfertility 3.1
ataxia 2.7
scaly skin 2.7
Spastic 2.6
Tenderness 2.6
Opposition 2.4
hand pain 2.4
loss of balance 2.3
Halo 2.3
ACHE 2.2
bradykinesia 2.2
prostatism 1.9
Psychiatric symptoms 1.8
intention tremor 1.7
joint stiffness 1.6
mastalgia 1.5
irregular bleeding 1.5
decreased appetite 1.5
Scratch 1.5
memory loss 1.5
general problem 1.4
incoordination 1.3
cerebellar ataxia 1.3
Spots 1.3
weakness 1.3
heel pain 1.2
anorexia 1.2
rundown 1.1
more...
Drug
Methionine Sulfoxide 9.1
Bortezomib 8.7
Montirelin 7.8
Ammonium phosphate 7.5
Dibasic calcium phosphate 7.3
Kifunensine 7.1
Thalomid 6.9
3,4-Dichloroisocoumarin 6.7
Tanespimycin 6.6
Parkin 6.5
Parkin 6.5
CXD 6.4
Indisulam 6.3
Apomorphine hydrochloride 6.3
Toad venom 6.0
AMC 5.7
Bindarit 5.6
Revlimid 5.6
8-Azaguanine 5.4
Romidepsin 5.3
K201 5.1
Radicicol 5.0
Lenalidomide 5.0
Resovist 4.9
CA-074 4.9
Flavopiridol 4.7
Tolfenamic acid 4.7
Peridinin 4.7
Vorinostat 4.6
ATV 4.6
Fulvestrant 4.5
Onconase 4.4
Sinefungin 4.3
DFP 4.3
Primperan 4.1
Auranofin 4.0
Tipifarnib 4.0
Arsenic trioxide 3.9
NVP 3.9
SPP 3.9
more...
Enzyme
proteasome 10.1
proteasome ATPase 9.7
spermosin 8.9
Ht-b 8.5
blasticidin-S deaminase 8.5
ubiquityl-calmodulin synthetase 8.1
ubiquitin-protein ligase 8.0
isopeptidase 7.6
arginyltransferase 7.5
thermomycolase 7.3
pseudolysin 7.2
NS protease 7.1
peptidoglutaminase 7.1
glucosamine kinase 7.1
succinyl-diaminopimelate desuccinylase 6.8
serralysin 6.8
bleomycin hydrolase 6.8
oligopeptidase A 6.7
phosphoenolpyruvate-protein phosphotransferase 6.7
prozyme 6.7
carboxypeptidase 1 6.5
nepenthesin 6.4
aspartyl aminopeptidase 6.4
retinoid isomerase 6.3
mannosidase I 6.3
m-calpain 6.2
carboxypeptidase S 6.2
thimet oligopeptidase 6.0
Aeromonas proteolytica aminopeptidase 5.9
lecithin-retinol acyltransferase 5.9
tail-specific protease 5.9
PcpB 5.9
ketopantoate hydroxymethyltransferase 5.8
nicotinamide adenine dinucleotide glycohydrolase 5.8
thermitase 5.8
vibriolysin 5.7
protease La 5.7
calpain 10 5.7
ClpP 5.7
3-hydroxyisobutyryl-CoA hydrolase 5.6
more...
Compound
2-methylmalonamide 10.1
C8H6O2 10.1
Tris-p-nitrophenyl phosphate 10.1
C8H6O2 10.1
Erioflorin 10.1
MCP 9.8
C30H22O4 9.1
C22H30O5 9.1
2-Nitrodiphenylamine 8.5
2-Nitrodiphenylamine 8.5
Antimycin A1 8.5
C7H4N2O2 8.1
C10H10O2 8.1
Sanggenon C 8.1
C7H4N2O2 8.1
C7H4N2O2 8.1
Ubiquitin 8.0
C7H4N2O2 7.8
Robinin 7.8
Robinin 7.8
C7H4N2O2 7.8
Caffeoyl-CoA 7.8
N-Acetylimidazole 7.8
Dibenzalacetone 7.5
C7H4N2O2 7.5
3-methylcyclopentanone 7.4
CHIP 7.4
4-methylpentanamide 7.3
Flumidin 7.1
C5H8O 7.1
Thiostrepton 7.1
Calpeptin 7.0
4-chloro-2-methylphenol 7.0
Cucurbitacin D 6.9
Calotropin 6.9
RUB 6.8
Ethyl linoleate 6.8
Calotropin 6.8
UPP 6.7
Calotropin 6.7
more...