Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.25.1 (proteasome)
28,817 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein proteasome 26143 ubiquitin 11111 Mol 3420 proteasome inhibitor 2336 Sep 1729 endoplasmic reticulum 1706 MCP 1571 p53 1145 Ubiquitin 1094 ATP 1042 Proteasome 1039 E3 ubiquitin ligase 994 ubiquitin ligase 974 ATPase 767 chymotrypsin-like 711 cytokine 551 caspase-3 521 insulin 492 SCF 479 MHC class I 466 polypeptide 416 mTOR 408 Bcl-2 397 peptidase 379 p21 367 calpain 341 interferon 319 threonine 306 histone 299 p27 297 F-box protein 291 tumor necrosis factor 290 LMP7 286 p62 279 MAPK 277 cyclin 274 fused 274 major histocompatibility complex 271 SDS 268 histone deacetylase 268 more...

Disease cancer 4327 tumor 2451 multiple myeloma 1373 Parkinson's disease 831 Alzheimer's disease 713 breast cancer 606 tumorigenesis 483 leukemia 427 muscular atrophy 398 tumor growth 390 HIV 335 hepatocellular carcinoma 315 amyotrophic lateral sclerosis 291 diabetes 285 prostate cancer 279 Huntington's disease 272 carcinogenesis 271 SDS 269 carcinoma 255 virus infection 251 lymphoma 237 lung cancer 232 abdominal aortic aneurysm 228 melanoma 227 neuroblastoma 225 AAA 224 tumor progression 214 MCF 189 APC 183 immunodeficiency 172 dementia 171 ischemia 170 cold 165 colon cancer 162 mantle cell lymphoma 155 Hippel 154 colorectal cancer 153 adenocarcinoma 147 heart failure 147 cytomegalovirus 142 more...

Symptom starvation 257 cachexia 171 ataxia 96 pain 88 weakness 83 collapse 50 fatigue 44 diarrhea 33 seizures 32 anorexia 28 tremor 26 vomiting 18 exhaustion 17 agitation 16 functional recovery 15 acidity 15 nausea 15 respiratory distress 14 dystonia 12 erythema 12 headache 11 bradykinesia 10 hyperoxia 9 acute stress 9 hypothermia 9 memory loss 9 hypotonia 9 dyspnea 8 cerebellar ataxia 8 anesthesia 8 nausea and vomiting 7 arthralgia 7 discomfort 6 bone pain 6 overweight 6 thinning 5 asthenia 5 myalgia 5 numbness 5 discomfort 5 more...

Drug lysine 610 Bortezomib 544 Parkin 155 Parkin 155 IFN-gamma 154 ROS 134 Cardiovasc 67 AMC 56 CSF 45 IL-2 43 Dermatol 40 MAP 38 Asn 36 ascorbate 31 Gel 29 Leaf 23 NADH 23 vitamin E 21 Lenalidomide 19 Arsenic trioxide 17 Ethanol 17 DFP 16 caffeine 16 ABC 16 Angiotensin II 16 ICI 15 G-CSF 15 Alanine 14 Kenyan 14 CAM 14 Nitric Oxide 13 CaCl2 13 CaCl2 13 Rituximab 13 CaCl2 13 Adriamycin 13 NVP 13 citric acid 12 ETS 11 Imatinib 11 more...

Enzyme proteasome 28817 protein kinase 855 mitogen-activated protein kinase 848 ATPase 793 trypsin 503 ERK 437 caspase-3 424 focal adhesion kinase 208 APC 202 luciferase 201 protein kinase C 199 cdc2 188 ubiquitin-protein ligase 188 MEK 177 IKK 175 RNA polymerase 168 chymotrypsin 161 calcineurin 142 elastase 138 PARP 135 superoxide dismutase 132 glutathione S-transferase 130 caspase-8 123 ornithine decarboxylase 123 AMP-activated protein kinase 109 cathepsin B 105 isopeptidase 101 ACS 96 catalase 94 GSK 94 phosphatidylinositol 3-kinase 92 subtilisin 89 caspase-9 89 AMPK 88 RNase 78 RNase 74 topoisomerase 71 AMPK 67 topoisomerase 67 peroxidase 61 more...

Compound DNA 2529 Dec 1986 MCP 1571 ATP 1042 oxygen 960 lysine 803 serine 639 Ubiquitin 619 tyrosine 539 calcium 507 Clin 492 leucine 481 glucose 471 threonine 464 cysteine 432 alanine 386 arginine 323 SDS 278 sodium 274 water 273 TNF 235 AAA 224 nitrogen 213 iron 199 nitric oxide 195 hydrogen 194 zinc 190 aldehyde 187 phosphate 187 methionine 184 Phe 183 aldehyde 172 cAMP 162 proline 151 salt 151 MDA 146 sulfate 146 His 144 Asp 141 glutamate 141 more...

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