Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.25.1 (
proteasome
)
28,817
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
proteasome
0.907
ubiquitin
0.132
MCP
0.055
proteasome inhibitor
0.040
Proteasome
0.027
chymotrypsin-like
0.010
Ubiquitin
0.010
ubiquitin ligase
0.006
E3 ubiquitin ligase
0.006
LMP7
0.006
Rpn10
0.004
LMP2
0.003
F-box protein
0.002
COP9
0.002
SCF
0.002
atrogin-1
0.002
Rpn13
0.002
PA28alpha
0.002
p97
0.002
Rpn11
0.002
more...
Disease
multiple myeloma
0.002
muscular atrophy
0.001
cancer
0.001
AAA
0.001
Parkinson's disease
0.000
tumor
0.000
mantle cell lymphoma
0.000
abdominal aortic aneurysm
0.000
Huntington's disease
0.000
Hippel
0.000
Alzheimer's disease
0.000
amyotrophic lateral sclerosis
0.000
tumorigenesis
0.000
APC
0.000
tumor growth
0.000
IBMPFD
0.000
aHUS
0.000
breast cancer
0.000
hematologic malignancies
0.000
leukemia
0.000
more...
Symptom
cachexia
0.000
starvation
0.000
ataxia
0.000
CNS symptom
0.000
Diaphragmatic weakness
0.000
weakness
0.000
Localized pain
0.000
collapse
0.000
autodigestion
0.000
Organ failure
0.000
Ear swelling
0.000
anorexia
0.000
Cold intolerance
0.000
bradykinesia
0.000
Hyperextension
0.000
Positive and Negative Symptoms
0.000
tremor
0.000
fatigue
0.000
male subfertility
0.000
facial droop
0.000
more...
Drug
Bortezomib
0.007
Parkin
0.000
Parkin
0.000
lysine
0.000
AMC
0.000
Methionine Sulfoxide
0.000
ROS
0.000
IFN-gamma
0.000
Lenalidomide
0.000
Montirelin
0.000
Ammonium phosphate
0.000
Kifunensine
0.000
Dibasic calcium phosphate
0.000
Thalomid
0.000
Tanespimycin
0.000
DFP
0.000
3,4-Dichloroisocoumarin
0.000
CXD
0.000
Arsenic trioxide
0.000
Apomorphine hydrochloride
0.000
more...
Enzyme
proteasome
1.000
ubiquitin-protein ligase
0.002
isopeptidase
0.001
ATPase
0.000
proteasome ATPase
0.000
protein kinase
0.000
mitogen-activated protein kinase
0.000
IKK
0.000
trypsin
0.000
caspase-3
0.000
cdc2
0.000
m-calpain
0.000
cathepsin B
0.000
APC
0.000
ornithine decarboxylase
0.000
chymotrypsin
0.000
spermosin
0.000
caspase-8
0.000
elastase
0.000
ERK
0.000
more...
Compound
MCP
0.044
Ubiquitin
0.005
CHIP
0.001
AAA
0.001
TAP
0.000
ATP
0.000
lysine
0.000
DNA
0.000
serine
0.000
threonine
0.000
leucine
0.000
tyrosine
0.000
NOXA
0.000
oxygen
0.000
cysteine
0.000
Cbl
0.000
alanine
0.000
Geldanamycin
0.000
Dec
0.000
Ethylene
0.000
more...