Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.25.1 (proteasome)
 28,817 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
proteasome 26143
ubiquitin 11111
Mol 3420
proteasome inhibitor 2336
Sep 1729
endoplasmic reticulum 1706
MCP 1571
p53 1145
Ubiquitin 1094
ATP 1042
Proteasome 1039
E3 ubiquitin ligase 994
ubiquitin ligase 974
ATPase 767
chymotrypsin-like 711
cytokine 551
caspase-3 521
insulin 492
SCF 479
MHC class I 466
more...
Disease
cancer 4327
tumor 2451
multiple myeloma 1373
Parkinson's disease 831
Alzheimer's disease 713
breast cancer 606
tumorigenesis 483
leukemia 427
muscular atrophy 398
tumor growth 390
HIV 335
hepatocellular carcinoma 315
amyotrophic lateral sclerosis 291
diabetes 285
prostate cancer 279
Huntington's disease 272
carcinogenesis 271
SDS 269
carcinoma 255
virus infection 251
more...
Symptom
starvation 257
cachexia 171
ataxia 96
pain 88
weakness 83
collapse 50
fatigue 44
diarrhea 33
seizures 32
anorexia 28
tremor 26
vomiting 18
exhaustion 17
agitation 16
acidity 15
functional recovery 15
nausea 15
respiratory distress 14
dystonia 12
erythema 12
more...
Drug
lysine 610
Bortezomib 544
Parkin 155
Parkin 155
IFN-gamma 154
ROS 134
Cardiovasc 67
AMC 56
CSF 45
IL-2 43
Dermatol 40
MAP 38
Asn 36
ascorbate 31
Gel 29
NADH 23
Leaf 23
vitamin E 21
Lenalidomide 19
Ethanol 17
more...
Enzyme
proteasome 28817
protein kinase 855
mitogen-activated protein kinase 848
ATPase 793
trypsin 503
ERK 437
caspase-3 424
focal adhesion kinase 208
APC 202
luciferase 201
protein kinase C 199
cdc2 188
ubiquitin-protein ligase 188
MEK 177
IKK 175
RNA polymerase 168
chymotrypsin 161
calcineurin 142
elastase 138
PARP 135
more...
Compound
DNA 2529
Dec 1986
MCP 1571
ATP 1042
oxygen 960
lysine 803
serine 639
Ubiquitin 619
tyrosine 539
calcium 507
Clin 492
leucine 481
glucose 471
threonine 464
cysteine 432
alanine 386
arginine 323
SDS 278
sodium 274
water 273
more...