Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.25.1 (
proteasome
)
28,817
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
To investigate the cause of accumulation of oxidised proteins in the livers of rats with carbon tetrachloride (CCl4) induced liver cirrhosis, the activity of
alkaline protease
(a high molecular weight, multisubunit cysteine proteinase) was determined in the cirrhotic livers. A significant decrease (P < 0.05) in the activity of hepatic
alkaline protease
was observed in the cirrhotic rats.
Decreased activity
of
alkaline protease
in the liver of cirrhotic rats may contribute to the accumulation of the oxidised proteins in the liver.
...
PMID:Decreased activity of hepatic alkaline protease in rats with carbon tetrachloride-induced liver cirrhosis. 1086 92
