Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.B1 (
angiotensin-converting enzyme 2
)
1,025
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In silico
analysis revealed that a
lectin
, jacalin from jackfruit seeds, recognizes a glycosylated region of the receptor-binding domain (RBD) of SARS-CoV2. Jacalin binding induces conformational changes in RBD and significantly affects its interaction with human
angiotensin-converting enzyme 2
. The result may open up exploration of
lectin
-based strategies against COVID-19.
...
PMID:Targeting the glycan of receptor binding domain with jacalin as a novel approach to develop a treatment against COVID-19. 3304 45
