Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.69 (
botulinum neurotoxin
)
1,901
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
RAZ1
12.7
synaptotagmin II
11.9
SV2C
11.7
synaptotagmin IX
11.7
syntaxin 1C
11.7
Cellubrevin
11.3
HECTD2
11.2
Myopalladin
11.2
VAMP5
11.0
SNAP protein
10.9
VAMP
10.7
VAMP1
10.6
synaptotagmin 2
10.5
VAMP-1
10.4
VAMP-2
10.2
amisyn
10.2
CDIP
10.0
SNAP-47
9.9
VCIP135
9.9
SNAP
9.8
Vesicle-associated membrane protein 2
9.8
SV2B
9.6
VAMP2
9.6
SNAP-23
9.6
cellubrevin
9.6
syntaxin
9.5
syntaxin 1A
9.5
VRP
9.5
SV2
9.4
SNARE
9.3
gcv
9.2
synaptotagmin VII
9.1
tomosyn
9.0
VAMP7
9.0
SV2A
8.9
N-ethylmaleimide-sensitive factor
8.9
syntaxin 3
8.8
Synaptosomal-associated protein
8.8
syntaxin 4
8.7
21 kDa protein
8.7
N-ethylmaleimide-sensitive fusion protein
8.7
Q-SNARE
8.6
P47
8.4
syntaxin 1B
8.3
alpha-SNAP
8.3
AAAT
8.3
GAT-2
8.2
HLA DQA1
8.1
VIP2
8.1
MAPA
8.0
VAMP4
7.9
P2'
7.9
BTF
7.9
TSN
7.9
MLD
7.9
heavy chain
7.8
LCB
7.8
S100A13
7.8
L21
7.7
choline acetylase
7.7
synaptotagmin I
7.7
L19
7.7
GLYT1
7.7
VAMP-8
7.7
L14
7.7
CARP
7.6
v-SNARE
7.6
NSF
7.6
C1D
7.5
HCR
7.5
LNP
7.4
Hb1
7.4
soluble NSF attachment protein
7.4
BSG
7.3
GalNAc-transferase
7.3
metalloprotease
7.3
P33
7.3
endoprotease
7.3
P140
7.2
VAMP3
7.2
zinc metallopeptidase
7.2
SUFU
7.2
GalNAcT
7.1
R-SNARE
7.1
BASP1
7.1
Glycophorin A
7.0
heavy chain variable region
7.0
34 kD
7.0
neuronal protein
6.9
GM3 synthase
6.8
KA1
6.8
zinc-binding protein
6.7
beta-3
6.7
RAMP
6.7
L15
6.7
KChIP2
6.7
synaptotagmin 1
6.7
L23
6.7
dynamin 1
6.6
MNT
6.6
LCE
6.6
PNG
6.5
ST7
6.5
glycoprotein 2
6.5
L18
6.5
KA2
6.5
EPM
6.3
L13
6.3
ST4
6.3
24 kDa protein
6.3
syntaxin-4
6.3
L30
6.3
L17
6.2
xenin
6.2
Aplysia
6.1
NBP
6.1
p47
6.0
L22
6.0
MNB
6.0
strabismus
6.0
telomerase catalytic subunit
6.0
TCI
5.9
prothymosin alpha
5.9
GAT1
5.9
L12
5.9
GHRH receptor
5.9
LCA
5.8
elastase inhibitor
5.8
LPA1
5.8
gephyrin
5.8
Myosin heavy chain
5.8
N-acetylgalactosaminyltransferase
5.8
ATP receptor
5.7
CD205
5.7
growth hormone releasing hormone
5.7
Nav1.7
5.7
L10
5.6
MEP
5.6
Myf-5
5.6
Dihydrofolate reductase
5.6
ADP-ribosyltransferase
5.6
NR2C
5.6
ChAT
5.6
choline transporter
5.6
HA1
5.6
actin-depolymerizing factor
5.6
RIL
5.5
Titin
5.5
Golgi protein
5.5
vesicular acetylcholine transporter
5.5
Drosophila)
5.5
L16
5.5
MPN
5.5
CGRP
5.5
GAP43
5.5
chromogranin B
5.4
amphiphysin
5.4
cot
5.4
TRPV1
5.4
myelin protein zero
5.3
BAT
5.3
NTM
5.3
triadin
5.3
docking protein
5.3
GABA transporter
5.3
PGP
5.3
DSP-4
5.3
signal peptidase
5.3
GLT1
5.3
ankyrin 1
5.3
glutamate receptor subunit
5.2
MuRF1
5.2
SCP
5.2
Synaptophysin
5.2
CYC1
5.2
scFv
5.2
member 1
5.2
MLP
5.1
B antigen
5.1
CTRL
5.1
C-terminal peptide
5.1
membrane protein
5.1
DQA1
5.0
PHP
5.0
P2X1
5.0
C protein
5.0
C21
5.0
B17
5.0
PPS
5.0
HPP
4.9
Kv4.2
4.9
complement receptor
4.9
MDC
4.9
TRPA1
4.9
P18
4.9
CAPS
4.9
differentially expressed protein
4.9
Kv4
4.8
titin
4.8
MCD
4.8
CIC
4.8
L11
4.8
CPI
4.8
Flt3 ligand
4.7
P2X2
4.7
Na+/Ca2+ exchanger
4.7
C15
4.7
wts
4.7
CD1
4.7
small GTP-binding protein
4.6
Haptoglobin
4.6
Reelin
4.6
IVA
4.6
P2X3
4.6
Kv1.2
4.6
p18
4.6
CCL22
4.6
Cholinesterase
4.6
p75(NTR)
4.5
orf
4.5
mer
4.5
HA2
4.5
putative function
4.5
PS2
4.4
CDC42
4.4
HSF
4.4
choline acetyltransferase
4.4
CH1
4.4
LPA
4.4
MAD
4.3
DR7
4.3
C11
4.3
HES
4.3
DMPK
4.3
ADL
4.3
neurotransmitter receptor
4.3
deubiquitinating enzyme
4.3
C10
4.3
synaptophysin
4.3
SUR1
4.3
transient receptor potential vanilloid 1
4.2
netrin-1
4.2
ABS
4.2
EFS
4.2
ASP
4.2
HLA-DR3
4.2
SAA
4.2
Trx
4.2
septin
4.2
INS-1
4.2
HLA-DRB1
4.2
metallopeptidase
4.2
DQB1
4.2
ECL
4.2
sulfonylurea receptor
4.1
Phospholipase A2
4.1
alpha-L-fucosidase
4.1
FM1
4.1
glycogen synthase kinase 3
4.1
vesicular monoamine transporter 2
4.1
cys
4.1
IDO
4.1
purinergic receptor
4.0
LAP
4.0
chimeric protein
4.0
Janus kinase 2
4.0
Trypsin
3.9
CFP
3.9
APB
3.9
NK1
3.9
synapsin I
3.9
GLUT4
3.9
EMD
3.9
Rab7
3.8
PPP
3.8
MCP-3
3.8
P2X
3.8
FMLP
3.8
amino acid transporter
3.8
P15
3.8
aminopeptidase
3.8
substance P
3.7
PTC
3.7
superoxide dismutase 1
3.7
MES
3.7
DNMT3B
3.7
calcitonin
3.7
mGluR5
3.7
histidine decarboxylase
3.7
CD43
3.6
cell surface receptor
3.6
frataxin
3.6
SCI
3.6
metabotropic glutamate receptor
3.6
UTI
3.6
ciliary neurotrophic factor
3.6
sarcomeric
3.5
nephrin
3.5
DAT
3.5
apoptosis-inducing factor
3.5
MAT
3.5
HCC
3.5
neuraminidase
3.5
SAP
3.5
sialyltransferase
3.5
CPA
3.4
MAP2
3.4
HPO
3.4
DNA ligase
3.4
SPR
3.4
adenosine A1 receptor
3.4
28 kDa
3.3
Kir6.2
3.3
chymotrypsin-like
3.3
adapter protein
3.3
thioredoxin
3.3
nerve growth factor
3.3
cell surface protein
3.2
GAP-43
3.2
protein kinase inhibitor
3.2
axonal
3.2
novel gene
3.2
LIF
3.2
P19
3.2
serotonin transporter
3.1
connexin 43
3.1
RCM
3.1
lacrimal
3.1
phospholipase A2
3.1
dopamine beta-hydroxylase
3.1
SDS
3.1
serum amyloid A
3.1
C30
3.0
p55
3.0
fused
3.0
GTP-binding protein
3.0
E11
3.0
ORF
3.0
Rho kinase
3.0
G-protein coupled receptor
3.0
myostatin
3.0
muscarinic receptor
2.9
dopamine transporter
2.9
STS
2.9
amyloid precursor protein
2.9
DR3
2.9
TRAP
2.9
cytoskeletal protein
2.9
GMP
2.8
binding peptide
2.8
MCM
2.8
prion
2.8
myogenin
2.8
inhibitor 2
2.8
thioredoxin reductase
2.8
CR1
2.8
prostate-specific antigen
2.8
serine protease inhibitor
2.8
mouse)
2.8
PKG
2.7
glutamate transporter
2.7
NR1
2.7
E.coli
2.7
Ca2+-ATPase
2.7
low-density lipoprotein receptor
2.7
rat)
2.7
E14
2.7
C17
2.7
sialidase
2.6
receptor kinase
2.6
L-type calcium channel
2.6
CA3
2.6
cytoplasmic protein
2.6
p40
2.6
anti-apoptotic protein
2.6
NR2B
2.6
acetylcholine receptor
2.6
HSA
2.5
RhoA
2.5
Erythropoietin
2.5
ABC
2.5
AAA
2.5
ICD
2.5
neurotrophin
2.5
chromogranin A
2.5
gag
2.5
peptidase
2.5
MyoD
2.5
myosin heavy chain
2.5
P21
2.4
NAD+
2.4
GHRH
2.4
PDF
2.4
GST
2.4
calretinin
2.4
amylase
2.4
IGF-1
2.3
ALS
2.3
dynamin
2.3
polypeptide
2.3
thyrotropin-releasing hormone
2.3
alpha-smooth muscle actin
2.2
p75
2.2
LL)
2.2
glucose transporter
2.2
butyrylcholinesterase
2.2
SAR
2.2
metalloproteinase
2.2
E-cadherin
2.1
colon carcinoma
2.1
transcriptional regulator
2.1
MAS
2.1
non-functional
2.1
NMDA receptor
2.0
lamp
2.0
TOF
2.0
hinge
2.0
Vascular endothelial growth factor
2.0
SOD1
2.0
ADP
2.0
ALP
2.0
Ubiquitin
2.0
Met
2.0
MHC
1.9
acetylcholinesterase
1.9
glutathione S-transferase
1.9
galactosamine
1.9
ANOVA
1.9
Gag
1.9
cysteine protease
1.9
GTP
1.9
API
1.8
neurotrophic factor
1.8
PCA
1.8
CD11b
1.8
CD38
1.8
proteasome inhibitor
1.8
lectin
1.8
ABO
1.8
tropomyosin
1.8
vasoactive intestinal peptide
1.8
GTPase
1.8
CA1
1.8
MIP
1.8
PBS
1.8
glutamine synthetase
1.8
mast cell
1.8
kallikrein
1.7
brain-derived neurotrophic factor
1.7
adenosine deaminase
1.7
PDB
1.7
Rho
1.7
interleukin 6
1.7
calcium channel
1.7
dihydrofolate reductase
1.7
proteasome
1.7
serum albumin
1.7
ubiquitin ligase
1.7
dystrophin
1.6
core protein
1.6
integrase
1.6
PSA
1.6
glial fibrillary acidic protein
1.6
fur
1.6
GABA
1.6
opioid receptor
1.6
c-Jun
1.5
S100
1.5
gut
1.5
guanylate cyclase
1.4
interleukin-4
1.4
phospholipase
1.4
tissue plasminogen activator
1.4
EGF receptor
1.4
DNA-binding domain
1.4
adaptor protein
1.4
serum protein
1.4
transferrin receptor
1.3
ionotropic
1.3
peroxidase
1.3
EGFR
1.3
sodium channel
1.3
Hip
1.3
housekeeping
1.3
Chlamydomonas
1.3
p21
1.2
hormone receptor
1.2
transmembrane protein
1.2
interacting protein
1.2
esterase
1.2
5-hydroxytryptamine
1.2
epidermal growth factor
1.2
myelin basic protein
1.2
CCK
1.2
Sp1
1.2
PKA
1.2
mucin
1.1
tyrosine hydroxylase
1.1
ATP
1.1
proton pump
1.1
HEK
1.1
protease inhibitor
1.1
antioxidant enzyme
1.1
SMA
1.0
dilute
1.0
DNase I
1.0
CXCR4
1.0
lipase
1.0
X-linked
1.0
Gal
0.9
unknown function
0.9
adenylyl cyclase
0.9
transferrin
0.9
neuropeptide Y
0.8
cardiac muscle
0.8
caspase-9
0.8
endothelin-1
0.8
gastrin
0.8
membrane-bound
0.8
Mol
0.8
AMP
0.7
NAD
0.7
RNase
0.7
reserved
0.7
albumin
0.7
kit
0.7
IgA
0.6
ubiquitin
0.6
NHS
0.6
GDP
0.6
She
0.6
c-fos
0.6
caspase-3
0.5
Poly
0.5
extracellular signal-regulated kinase
0.5
olfactory
0.5
glycoprotein
0.5
insulin
0.4
endoplasmic reticulum
0.4
HLA-DR
0.4
surface antigen
0.4
lactate dehydrogenase
0.4
PKC
0.4
HLA
0.3
ras
0.3
tap
0.3
SARS
0.2
nitric oxide synthase
0.2
growth hormone
0.2
ATPase
0.2
Sep
0.1
alkaline phosphatase
0.1
microsomal
0.1
matrix metalloproteinase
0.1
VEGF
0.1
CO2
0.0
PLA
-0.0
IL-10
-0.1
casein
-0.1
cyclooxygenase
-0.1
adenylate cyclase
-0.1
interferon-gamma
-0.2
Mil
-0.2
ACS
-0.2
major histocompatibility complex
-0.2
ESI
-0.3
SOD
-0.3
cytokine
-0.3
beta-endorphin
-0.3
lysozyme
-0.3
MRI
-0.3
IFN
-0.4
ERK1
-0.4
CSF
-0.5
myosin
-0.5
C18
-0.5
cytochrome c
-0.5
IL-8
-0.5
interleukin-6
-0.5
dimeric
-0.5
calmodulin
-0.6
NADPH
-0.6
threonine
-0.6
chemokine
-0.6
IL-2
-0.8
prolactin
-0.8
LPS
-0.8
Rec
-0.8
IL-4
-0.8
NMR
-0.8
IgE
-0.9
Bcl-2
-1.0
thrombin
-1.0
tyrosine kinase
-1.1
CD4
-1.2
Pseudomonas
-1.2
Gen
-1.4
IL-6
-1.8
TNF
-1.9
interferon
-1.9
lipopolysaccharide
-1.9
Pol
-2.0
collagen
-2.9
Disease
Downer cow syndrome
12.4
Equine grass sickness
11.3
Primary focal hyperhidrosis
9.8
Wound botulism
9.3
Hunner
9.3
triplegia
9.1
Chronic migraine
9.1
Ross syndrome
8.7
BPS
8.3
Overactive bladder
8.0
interstitial cystitis
7.9
Myofascial pain syndrome
7.8
autonomic disorder
7.6
anal fissure
7.5
tetanus
7.4
tennis elbow
7.1
plantar fasciitis
7.0
Ileum
6.8
disuse osteoporosis
6.7
Dystonia
6.6
hemiparkinsonism
6.6
dysautonomia
6.5
cerebral palsy
6.3
Wallenberg's syndrome
6.3
metachromatic leukodystrophy
6.3
anthrax
6.3
Chronic prostatitis
6.2
diplegia
6.1
toxemia
6.0
Bateman
5.8
nocturia
5.8
orphan disease
5.8
chondrolysis
5.7
dysphonia
5.6
lagophthalmos
5.6
regional pain syndrome
5.5
Venezuelan equine encephalitis
5.5
gas gangrene
5.5
EBM
5.5
postherpetic neuralgia
5.5
DIG
5.4
Hailey-Hailey disease
5.4
Hereditary spastic paraplegia
5.4
sialolithiasis
5.4
Marion
5.3
trigeminal neuralgia
5.2
generalized disease
5.2
movement disorder
5.2
SCP
5.2
migraine
5.1
neuromyotonia
5.1
LCA
5.1
Lower limb
5.1
PHP
5.0
insulinoma
5.0
CNF
4.9
strabismus
4.9
HPP
4.9
phantom limb pain
4.9
Thomsen
4.9
HPP
4.8
spastic diplegia
4.8
hemoglobinuria
4.8
ventral hernia
4.8
MCD
4.8
Lambert-Eaton myasthenic syndrome
4.7
serum sickness
4.6
prostatitis
4.6
joint effusion
4.6
gastroparesis
4.6
achalasia
4.6
IVA
4.5
incontinence
4.5
Worms
4.5
akinesia
4.5
tetany
4.4
Raynaud
4.4
prostatic disease
4.4
chronic pain
4.3
nerve entrapment
4.2
ABS
4.2
diabetic neuropathy
4.2
prolapse
4.2
orf
4.2
dysphagia
4.2
Tongue
4.1
ABS
4.1
Rosenthal
4.1
acute disease
4.0
xerostomia
4.0
HES
4.0
esotropia
3.9
trismus
3.9
bruxism
3.9
sialadenitis
3.9
carpal tunnel syndrome
3.8
PPP
3.8
nerve lesion
3.8
LAP
3.8
sensory disturbance
3.8
thiamine deficiency
3.8
incontinence
3.7
diplopia
3.7
Bladder
3.7
Bladder
3.7
Bladder
3.7
Frey
3.7
neuromuscular disorder
3.7
RCM
3.6
priapism
3.6
apraxia
3.6
EMD
3.5
Mitchell
3.5
HCC
3.5
respiratory acidosis
3.5
rosacea
3.4
disinhibition
3.4
neuroblastoma
3.4
compartment syndrome
3.3
EDC
3.3
neurogenic bladder
3.2
status epilepticus
3.2
neurological disease
3.2
diphtheria
3.2
cholera
3.2
Jensen
3.1
stress incontinence
3.1
Robinson
3.1
cardiovascular risk factor
3.1
SDS
3.1
acromegaly
3.0
temporal lobe epilepsy
3.0
Friedreich's ataxia
3.0
hemiparesis
2.9
fecal incontinence
2.9
urinary tract infection
2.8
cognitive deficit
2.8
neuroendocrine tumor
2.8
STS
2.7
Parkinson's disease
2.7
tardive dyskinesia
2.7
CNS diseases
2.7
rabies
2.7
Schmidt
2.6
muscular atrophy
2.6
varices
2.6
multiple sclerosis
2.5
parkinsonism
2.5
mimicry
2.5
motor neuron disease
2.5
tetraplegia
2.5
ARF
2.5
Charcot-Marie-Tooth disease
2.5
AAA
2.5
Evans
2.5
ICD
2.4
hepatitis E
2.4
Adenovirus
2.4
astigmatism
2.4
Langerhans cell histiocytosis
2.4
stroke
2.4
smallpox
2.3
embryonal carcinoma
2.3
medullary thyroid carcinoma
2.3
meninges
2.2
pheochromocytoma
2.2
impotence
2.2
SAR
2.2
hamartoma
2.2
papillary thyroid cancer
2.1
urolithiasis
2.1
facial palsy
2.1
sudden infant death syndrome
2.1
Giant
2.0
cystitis
2.0
Hashimoto's thyroiditis
1.9
Blocking
1.9
lipoma
1.9
transient ischemic attack
1.8
fibromyalgia
1.8
PCA
1.8
MAS
1.8
amyotrophic lateral sclerosis
1.8
respiratory failure
1.8
MIP
1.7
osteoarthritis
1.7
Shiga
1.7
emotional distress
1.7
dyskinesia
1.7
zoonosis
1.6
PSA
1.6
affective disorder
1.6
neuropathy
1.5
carcinoma in situ
1.5
skin disease
1.4
paraplegia
1.4
rare disease
1.4
acne
1.3
PDB
1.3
dermatitis
1.3
psoriasis
1.3
erectile dysfunction
1.3
carcinoid
1.3
myasthenia gravis
1.2
liver cancer
1.1
coma
1.1
irritable bowel syndrome
1.1
Proteus
1.0
diabetic retinopathy
1.0
abdominal aortic aneurysm
1.0
pneumothorax
0.9
Still
0.9
depression
0.9
epilepsy
0.9
urethra
0.8
SARS
0.8
influenza
0.8
Yersinia
0.8
fits
0.7
peripheral neuropathy
0.7
cleft palate
0.7
mole
0.7
plaque
0.6
NHS
0.6
Nose
0.6
cold
0.5
amyloidosis
0.5
Poland
0.4
sarcoidosis
0.3
dementia
0.3
hydrocephalus
0.2
pruritus
0.2
hyperglycemia
0.2
bacterial infection
0.1
glioma
0.1
lupus
0.1
hernia
0.1
blindness
0.0
rash
0.0
infectious diseases
0.0
arthritis
-0.0
mole
-0.1
glioblastoma
-0.1
encephalitis
-0.1
pertussis
-0.2
meningitis
-0.3
Crohn's disease
-0.4
Alzheimer's disease
-0.4
lupus
-0.4
malaria
-0.4
glaucoma
-0.5
inflammatory bowel disease
-0.5
virus infection
-0.5
cystic fibrosis
-0.6
cytomegalovirus
-0.8
aggression
-0.8
psychosis
-0.8
chronic obstructive pulmonary disease
-0.8
Hodgkin's disease
-0.9
ischemia
-0.9
hepatocellular carcinoma
-1.1
multiple myeloma
-1.1
Infection
-1.2
systemic lupus erythematosus
-1.4
diabetes
-1.5
SEM
-1.5
carcinoma
-1.6
anemia
-1.6
sepsis
-1.6
Mycobacterium
-1.6
colorectal cancer
-1.7
pneumonia
-1.7
tumor growth
-1.8
sepsis
-1.8
obesity
-1.9
immunodeficiency
-2.1
atherosclerosis
-2.2
cancer
-2.2
asthma
-2.3
HIV
-2.3
leukemia
-2.5
metastases
-2.6
hypertension
-3.3
tumor
-3.4
Symptom
Spasmodic Torticollis
10.2
Prostatodynia
10.1
Cervical dystonia
9.9
Synkinesis
9.6
bladder pain
9.5
blepharospasm
9.2
Chronic pelvic pain syndrome
9.2
neurological pain
9.1
Breathiness
9.1
Palatal myoclonus
8.9
Spasmodic dysphonia
8.1
spasticity
8.1
Chronic pelvic pain
8.0
hand pain
7.9
No toxic effect
7.7
dystonia
7.7
Motor dysfunction
7.7
drooling
7.4
hypertonia
6.9
Spastic
6.6
pachyonychia
6.5
spasm
6.2
torticollis
6.2
motor symptom
6.2
orofacial pain
6.1
excessive sweating
5.9
limb pain
5.6
Neuropathic pain
5.6
pelvic pain
5.5
muscle stiffness
5.4
paresis
5.0
urinary frequency
4.9
neuralgia
4.9
dry eye
4.7
clonus
4.5
hemiplegia
4.4
neurological disability
4.2
knee pain
4.2
Hudson
4.0
weakness
3.9
stridor
3.8
facial pain
3.8
functional recovery
3.6
shoulder pain
3.6
low back pain
3.6
lethargy
3.6
arthralgia
3.5
photophobia
3.4
constipation
3.3
pain
3.3
tremor
3.2
headache
3.2
sneezing
3.1
neck pain
3.1
acute pain
3.1
leg pain
3.0
twitching
3.0
blurred vision
3.0
myalgia
2.9
dysuria
2.8
pallor
2.7
hypotonia
2.5
HSA
2.5
acidity
2.5
back pain
2.5
colic
2.4
ophthalmoplegia
2.3
insomnia
2.2
dysarthria
2.2
myoclonus
2.0
analgesia
1.8
paresthesia
1.8
shortness of breath
1.7
flushing
1.4
discomfort
1.2
ataxia
1.1
discomfort
1.0
seizures
0.9
syncope
0.9
distraction
0.8
dizziness
0.8
fatigue
0.7
agitation
0.5
erythema
0.3
stigma
0.3
collapse
0.2
vomiting
0.1
respiratory distress
-0.2
cough
-0.5
overweight
-0.7
anesthesia
-0.7
dyspnea
-0.7
diarrhea
-1.8
Drug
BoNT/A
13.1
BOTOX
11.4
Myobloc
11.0
Botox
10.6
Elm
8.0
Diphenhydramine
7.7
Ammonium chloride
6.2
Myricetin
5.8
Glide
4.7
Kainic acid
4.7
Xanthium
4.3
Adenosine triphosphate
4.2
Alanine
4.2
Clopidogrel
3.9
Fragment
3.9
Apomorphine
3.8
DPA
3.7
Meth
3.6
PTC
3.3
Asn
3.1
Theophylline
3.0
pyridoxal phosphate
2.7
Nitric Oxide
2.7
ABC
2.5
Taxol
2.4
Atropine
2.3
niacin
2.2
p75
2.1
NH3
1.2
Gel
1.2
ROC
1.1
DNase I
1.0
lactose
1.0
nitroglycerin
0.9
Dermatol
0.8
Ethanol
0.8
CTX
0.7
lysine
0.2
MAP
0.1
Nephron
-0.1
IL-2
-0.8
CSF
-0.9
Monit
-1.1
Enzyme
botulinum neurotoxin
14.0
tetanus neurotoxin
11.9
serralysin
7.9
endoglycoceramidase
7.7
thiaminase
7.7
CD10
7.0
DD-carboxypeptidase
6.6
VIP1
6.6
thermolysin
6.3
GM3 synthase
6.3
astacin
6.1
clostripain
6.1
DD-carboxypeptidase
6.1
ricin
5.7
endo-beta-galactosidase
5.7
ADP-ribosyltransferase
5.6
PNL
5.6
ADP-ribosyltransferase
5.6
BAT
5.3
SCP
5.2
endo-beta-galactosidase
5.1
Hageman factor
5.0
choline acetyltransferase
4.6
SPC
3.7
dopamine beta-hydroxylase
3.6
trypsin
3.6
aequorin
3.5
transpeptidase
3.5
histidine decarboxylase
3.5
DAT
3.5
MAT
3.5
PNGase F
3.5
sialyltransferase
3.4
sialyltransferase
3.4
sialyltransferase
3.4
MAT
3.3
neuraminidase
3.2
proteinase K
3.0
pepsin
3.0
prostate-specific antigen
2.9
phospholipase A2
2.8
histidine kinase
2.8
thioredoxin reductase
2.8
PKG
2.7
sialidase
2.6
DNA ligase
2.6
DNA ligase
2.6
tryptase
2.6
firefly luciferase
2.6
protein kinase C
2.3
glutathione S-transferase
2.2
PARP
1.9
MIP
1.8
glutamine synthetase
1.7
deaminase
1.7
adenosine deaminase
1.7
adenosine deaminase
1.7
acetylcholinesterase
1.6
proteasome
1.5
dihydrofolate reductase
1.5
kallikrein
1.5
phospholipase C
1.4
RNA polymerase
1.3
urease
1.2
tyrosine hydroxylase
1.2
urease
1.2
caspase-9
1.2
NO synthase
1.1
guanylate cyclase
1.0
plasmin
0.9
topoisomerase
0.9
lipase
0.8
peroxidase
0.8
creatine kinase
0.8
transcriptase
0.8
topoisomerase
0.8
reverse transcriptase
0.7
monoamine oxidase
0.6
tissue plasminogen activator
0.6
cholinesterase
0.4
beta-lactamase
0.3
lactate dehydrogenase
0.2
alkaline phosphatase
0.1
ATPase
0.0
RNase
0.0
DNA polymerase
-0.0
RNase
-0.1
ACE
-0.1
collagenase
-0.1
adenylate cyclase
-0.2
ACS
-0.2
lysozyme
-0.4
mitogen-activated protein kinase
-0.9
thrombin
-1.0
caspase-3
-1.1
luciferase
-1.2
protein kinase
-1.3
focal adhesion kinase
-1.4
ERK
-1.5
Compound
7-(phenyl(8-quinolinylamino)methyl)-8-quinolinol
13.4
Botulinum toxin type A
10.7
4-amino-1-naphthol
10.1
disialyllactose
10.0
3-piperidinecarboxylic acid
9.8
3,4-DAP
8.8
Allergan
8.8
Diphenhydramine
8.3
8-quinolinol
7.1
8-quinolinol
7.1
8-quinolinol
7.1
8-quinolinol
7.1
8-quinolinol
7.1
8-quinolinol
7.0
A 150
7.0
Iodoacetamide
6.9
Saxitoxin
6.9
1,2-cyclohexanedione
6.6
Risedronate
6.5
Elan
6.5
8-quinolinol
6.5
MNT
6.5
8-quinolinol
6.3
Sarcosine
6.2
Elan
6.2
PMB
6.2
nitrosobenzene
6.1
BON
5.9
Ibotenic acid
5.9
Ibotenic acid
5.9
Topiramate
5.8
Tacrine
5.8
ONA
5.7
MEP
5.6
MEP
5.5
Calcein
5.4
GM2
5.3
GM3
5.3
Nitrendipine
5.2
His-Leu
5.2
GD3
5.1
Alum
5.0
DETA
5.0
B17
4.9
Glu-Glu
4.9
myricetin
4.9
Isoform
4.8
Kainic acid
4.7
Kainic acid
4.7
Phorbol
4.6
GM1
4.6
adamantane
4.5
HEPES
4.4
zinc
4.4
MAD
4.3
Brefeldin A
4.3
Brefeldin A
4.3
norleucine
4.3
Alanine
4.2
Nodular
4.2
Chloroquine
4.2
Chloroquine
4.2
DMP
4.1
DTT
4.1
hippurate
4.1
DTT
4.0
norleucine
4.0
Trypsin
3.9
DPA
3.9
DPA
3.9
4-AP
3.9
Wortmannin
3.9
FMLP
3.9
DPA
3.8
dipropyl
3.8
DPA
3.7
keratan sulfate
3.7
POP
3.7
DPA
3.7
MES
3.7
MES
3.7
Tyrosine
3.7
1,3,5-hexatriene
3.7
1,3,5-hexatriene
3.7
Capsaicin
3.7
1,3,5-hexatriene
3.7
MPA
3.6
DAB
3.6
MPA
3.6
DPA
3.6
CNQX
3.6
HPP
3.5
MPA
3.5
DAT
3.5
APV
3.5
DPA
3.5
Tetrodotoxin
3.5
DPA
3.5
DPA
3.5
DPA
3.5
DPA
3.5
DPA
3.5
guanidine
3.5
CPA
3.4
Amide
3.4
Amphetamine
3.4
Amphetamine
3.4
CPA
3.3
CPA
3.3
glutamate
3.3
EDC
3.2
ACh
3.2
nitrous acid
3.2
ADP-ribose
3.1
Tween 20
3.1
Agar
3.0
CPA
3.0
SDS
3.0
Ile
3.0
Rifampicin
3.0
Asp
2.9
sodium chloride
2.9
L-leucine
2.8
hyaluronic acid
2.8
NTA
2.7
isoxazole
2.7
Neu5Ac
2.7
formaldehyde
2.7
noradrenaline
2.6
Theophylline
2.6
Neuronal
2.6
Paclitaxel
2.5
thiophene
2.5
aspartic acid
2.5
AAA
2.5
ACM
2.5
gamma-aminobutyric acid
2.4
A 1
2.4
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
2.4
Glutamate
2.4
Substance P
2.4
formaldehyde
2.3
Atropine
2.3
Cysteine
2.3
Serine
2.3
Valproic acid
2.3
isoleucine
2.3
DNP
2.3
Tris
2.3
isoleucine
2.3
aluminum
2.2
alanine
2.2
His
2.2
tyrosine
2.2
tryptophan
2.2
arginine
2.2
PDB
2.2
Neurotol
2.2
glutamine
2.1
EDTA
2.1
EDTA
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
tryptophan
2.1
tryptophan
2.1
calcium
2.1
Phe
2.1
PMA
2.1
benzaldehyde
2.1
benzaldehyde
2.1
cysteine
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.1
benzaldehyde
2.0
2-mercaptoethanol
2.0
TOF
2.0
tryptophan
2.0
benzaldehyde
2.0
ADP
2.0
ADP
2.0
Triton
2.0
acrylamide
2.0
ALP
2.0
Thrombin
2.0
leucine
1.9
stearic acid
1.9
stearic acid
1.9
Tris
1.9
glycerol
1.9
kaempferol
1.9
GMP
1.9
sulfate
1.8
stearic acid
1.8
ADP
1.8
dicarboxylic acid
1.8
GTP
1.8
hydroxide
1.7
aspartic acid
1.7
MPTP
1.7
aspartic acid
1.7
cGMP
1.7
NMDA
1.7
strontium
1.6
Norepinephrine
1.6
DMSO
1.6
HCl
1.6
lysine
1.6
pyrrolidine
1.6
glutamic acid
1.6
pyrrolidine
1.6
Gly
1.6
GABA
1.5
GABA
1.5
tin
1.5
Retinal
1.5
Testosterone
1.5
Testosterone
1.5
PMA
1.4
ADR
1.4
PLA
1.4
adenylate
1.4
diacetate
1.4
aspartic acid
1.4
Yellow
1.4
NAD
1.3
GalNAc
1.3
GlcNAc
1.3
ethyl acetate
1.3
Adenosine
1.3
6-12
1.2
tungsten
1.2
potassium
1.2
methanol
1.2
H2S
1.2
Triton X-100
1.1
dUTP
1.1
benzoic acid
1.1
nickel
1.1
ATP
1.1
NH2
1.1
H2S
1.0
nicotinamide
1.0
Adriamycin
1.0
Progesterone
1.0
Salt
1.0
Optimal
0.9
fluorine
0.9
phenol
0.9
TCA
0.9
sodium
0.9
BCG
0.9
galactose
0.8
chloroform
0.8
Mg2+
0.8
MAP
0.8
AMPA
0.8
acetate
0.8
silver
0.7
NAD
0.7
DNA
0.7
CTX
0.7
phosphoric acid
0.7
phosphate
0.7
AMP
0.7
ammonium
0.7
acetone
0.6
urea
0.6
threonine
0.6
GDP
0.6
THF
0.5
cAMP
0.5
methionine
0.5
retinoic acid
0.5
nitric oxide
0.4
iodine
0.4
Dec
0.4
serine
0.3
Off
0.3
cobalt
0.3
bromide
0.2
DEAE
0.1
hexane
0.1
water
0.1
TSH
0.1
ASA
0.1
proline
0.1
chlorine
0.1
barium
0.0
manganese
-0.0
CO2
-0.1
aldehyde
-0.2
ACS
-0.2
ACS
-0.2
pyrimidine
-0.3
pyrimidine
-0.3
glucose
-0.4
selenium
-0.4
salt
-0.4
NADPH
-0.6
NADPH
-0.6
aldehyde
-0.6
nitrate
-0.7
DSM
-0.7
methane
-0.7
mercury
-0.7
PEG
-0.8
Clin
-0.8
5-HT
-0.9
hydrogen
-1.0
cadmium
-1.1
oxygen
-1.1
PEG
-1.2
ammonia
-1.4
iron
-1.5
copper
-1.5
ethanol
-1.5
TNF
-1.9
nitrogen
-2.2
BMC
-3.5