Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.69 (
botulinum neurotoxin
)
1,901
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
SNAP
206
heavy chain
154
SNARE
132
Sep
132
syntaxin
82
Mol
64
membrane protein
59
VAMP
51
metalloprotease
46
N-ethylmaleimide-sensitive factor
31
VAMP-2
29
fused
28
SDS
25
axonal
24
polypeptide
21
SV2
17
substance P
17
mer
17
insulin
17
VAMP2
17
more...
Disease
tetanus
126
cerebral palsy
45
stroke
45
migraine
35
SDS
25
Parkinson's disease
25
chronic pain
23
depression
19
anthrax
19
incontinence
18
interstitial cystitis
18
neuroblastoma
17
strabismus
17
dysphagia
17
multiple sclerosis
15
cancer
14
prolapse
13
cholera
11
movement disorder
10
BPS
9
more...
Symptom
pain
153
spasticity
103
dystonia
102
blepharospasm
36
weakness
34
spasm
33
headache
30
bladder pain
17
paresis
11
pelvic pain
11
tremor
10
functional recovery
10
hypertonia
9
seizures
9
torticollis
7
drooling
7
low back pain
7
Spasmodic Torticollis
6
analgesia
6
Cervical dystonia
6
more...
Drug
BoNT/A
444
Botox
39
Dermatol
28
BOTOX
27
Diphenhydramine
13
Myobloc
7
Asn
6
lysine
4
ABC
3
Alanine
3
Gel
2
Fragment
2
lactose
2
nitroglycerin
1
Myricetin
1
NH3
1
CTX
1
DPA
1
Monit
1
Elm
1
more...
Enzyme
botulinum neurotoxin
1901
CD10
75
tetanus neurotoxin
44
trypsin
30
protein kinase C
14
ricin
10
thermolysin
9
choline acetyltransferase
9
neuraminidase
8
peroxidase
7
phospholipase A2
6
glutathione S-transferase
6
RNA polymerase
5
proteasome
5
acetylcholinesterase
5
ACS
4
pepsin
4
ATPase
4
PARP
3
ADP-ribosyltransferase
3
more...
Compound
Dec
164
zinc
109
calcium
85
DNA
82
Clin
52
water
45
glutamate
42
sodium
31
tyrosine
27
arginine
26
SDS
26
Botulinum toxin type A
26
sulfate
24
His
22
alanine
20
cysteine
19
ATP
17
phosphate
17
Asp
16
lysine
15
more...