Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.64 (
MPP
)
1,876
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MPP
1715
Mol
194
caspase-3
158
Sep
139
tyrosine hydroxylase
138
Bcl-2
103
ATP
97
estrogen receptor
67
synuclein
67
cytochrome c
60
GSH
60
superoxide dismutase
54
dopamine transporter
53
ROS
43
peptidase
41
PI3K
37
catalase
36
endoplasmic reticulum
36
alpha-synuclein
35
MAO-B
35
lactate dehydrogenase
34
cytochrome
34
ERK1
34
tumor necrosis factor
32
nitric oxide synthase
31
p53
30
inducible nitric oxide synthase
30
ERK
30
TNF
29
PPT
29
OCT1
28
lipopolysaccharide
28
p38
28
AKT
27
LC3
27
heme oxygenase-1
26
SOD
25
mTOR
25
organic cation transporter
24
insulin
24
glutathione peroxidase
24
OCT2
24
caspase-9
23
JNK
23
brain-derived neurotrophic factor
21
Nrf2
21
IL-6
20
hOCT2
20
ubiquitin
20
NAD
19
GSK
19
NADH
19
precursor protein
19
MAPK
18
c-Jun
18
NMR
18
LDH
18
proteasome
18
PTEN
17
LPS
17
organic cation transporter 1
17
cytochrome bc1
16
Parkin
16
neuronal nitric oxide synthase
15
calpain
15
PARP
15
glial fibrillary acidic protein
15
DJ-1
15
ADP
14
polypeptide
14
LPP
14
OCT3
14
glial cell line-derived neurotrophic factor
13
cytokine
13
erythroid
13
CA1
13
phosphatidylinositol 3-kinase
13
ATPase
13
p65
13
gut
13
more...
Disease
Parkinson's disease
846
neuroblastoma
153
parkinsonism
93
GSH
60
Alzheimer's disease
54
cancer
32
pheochromocytoma
20
tumor
18
movement disorder
15
depression
15
ischemia
12
stroke
10
breast cancer
10
tetanus
8
Friedreich's ataxia
8
SDS
7
MCF
7
abdominal aortic aneurysm
6
AAA
6
OPA1
6
dementia
6
pneumonia
6
Huntington's disease
6
cerebral ischemia
6
Mycoplasma
6
diabetes
6
NAME
6
dyskinesia
6
Pineal
6
hypertension
5
PPP
5
Blocking
5
amyotrophic lateral sclerosis
5
THC
5
osteoporosis
5
glioma
4
DDP
4
lymphoma
4
leukemia
4
erythropoietic protoporphyria
4
cold
4
B-cell lymphoma
4
malnutrition
4
Cannabis
4
epilepsy
4
MIP
4
prostate cancer
3
PARK2
3
catalepsy
3
melanoma
3
EMT
3
influenza
3
respiratory infection
3
acute myeloid leukemia
3
atherosclerosis
3
ATM
3
PARK7
3
type 2 diabetes
3
cognitive impairment
3
NOD
3
retinoblastoma
3
MTS
3
hypoglycemia
3
CNS diseases
2
West
2
MEC
2
iron overload
2
vagina
2
vaccinia
2
Mycoplasma pneumoniae pneumonia
2
mole
2
pulmonary hypertension
2
RDP
2
tumorigenesis
2
DMT1
2
lung cancer
2
optic atrophy
2
lichen
2
mole
2
TCP
2
more...
Symptom
collapse
16
bradykinesia
9
tremor
7
hypothermia
5
starvation
4
functional recovery
3
seizures
3
acidity
3
fatigue
3
pain
2
weakness
2
exhaustion
2
ataxia
1
anesthesia
1
muscle rigidity
1
constipation
1
sinus pressure
1
thinning
1
chorea
1
diarrhea
1
stigma
1
cerebellar ataxia
1
motor symptom
1
Scratch
1
hypotonia
1
nausea and vomiting
1
discomfort
1
Drug
ROS
43
ICI
27
NADH
19
Parkin
16
Parkin
16
EE2
12
lysine
10
Ringer's solution
9
caffeine
8
FAD
6
ascorbate
6
MAP
5
Estrogens
3
Glutathione
3
EPA
3
BH4
3
vitamin E
3
CSF
3
Reserpine
3
Heme
3
CFT
3
Gefitinib
2
Myricetin
2
Gel
2
ENT
2
Pramipexole
2
Leaf
2
Pramipexole
2
SPP
2
MDS
2
Rosiglitazone
2
Apomorphine
1
5-Nitroindazole
1
IFN-gamma
1
Ouabain
1
Spectrum
1
Lovastatin
1
Quinine,
1
TAT
1
Gelfoam
1
Fidarestat
1
Oxaliplatin
1
Bupleurum root
1
9-THC
1
Fluorescein
1
DHT
1
Valproic Acid
1
Salicylate
1
7-Nitroindazole
1
ISP
1
Ginseng
1
IL-2
1
citric acid
1
niacin
1
Indomethacin
1
Clopidogrel
1
Alsterpaullone
1
6-Nitroindazole
1
TEL
1
EMB
1
Compound 9
1
Tenoxicam
1
OTC
1
Vandetanib
1
Swertia
1
Ddc
1
Fructose
1
Cytidine
1
Spectrum
1
Ketoconazole
1
Poloxamer 188
1
DPA
1
Asoprisnil
1
Misoprostol
1
Fidarestat
1
Ipratropium bromide
1
OTC
1
RFP
1
Glutamic acid
1
Fluorescein
1
more...
Enzyme
MPP
1876
caspase-3
136
tyrosine hydroxylase
134
complex I
122
mitogen-activated protein kinase
97
superoxide dismutase
76
monoamine oxidase
50
ERK
40
catalase
39
protein kinase
37
lactate dehydrogenase
35
luciferase
28
glutathione peroxidase
24
caspase-9
22
MEK
22
PARP
21
GSK
21
diaphorase
19
proteasome
18
AMP-activated protein kinase
17
MIP
15
ATPase
15
focal adhesion kinase
14
ACS
13
phosphatidylinositol 3-kinase
13
NO synthase
12
NQO1
12
DAT
12
ATP synthase
11
succinate dehydrogenase
11
CPR
10
NADH dehydrogenase
9
AMPK
9
protein kinase C
9
peroxidase
9
MMP
8
NOS
8
calcineurin
8
cytochrome oxidase
8
NADPH oxidase
8
NADPH oxidase
8
AMPK
8
xanthine oxidase
7
malate dehydrogenase
7
P-glycoprotein
7
phosphoinositide 3-kinase
6
aconitase
6
PKG
6
caspase-1
6
ubiquinol-cytochrome c oxidoreductase
6
alkaline phosphatase
5
caspase-8
5
trypsin
5
aldehyde dehydrogenase
5
acetylcholinesterase
5
ACE
5
gamma-glutamylcysteine synthetase
4
glutathione reductase
4
dihydrofolate reductase
4
aldehyde dehydrogenase
4
aldehyde dehydrogenase
4
fumarase
4
diamine oxidase
4
aldehyde dehydrogenase
4
aldehyde dehydrogenase
4
renin
4
insulin-degrading enzyme
4
phospholipase A2
3
citrate synthase
3
phosphorylase
3
prolyl hydroxylase
3
heme oxygenase
3
ornithine transcarbamylase
3
dimethylglycine dehydrogenase
3
CD10
3
isocitrate dehydrogenase
3
creatine kinase
3
pyruvate dehydrogenase
3
isocitrate dehydrogenase
3
phosphodiesterase
3
more...
Compound
MPP
1715
MPP
1715
MPTP
396
oxygen
270
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
237
Dec
123
DNA
112
ATP
97
iron
70
GSH
62
GSH
62
calcium
61
MTT
58
nitric oxide
57
1-Methyl-4-phenylpyridinium
47
glutamate
44
sodium
40
NAD
37
water
35
arginine
35
hydrogen
35
iodine
32
4-phenylpyridine
32
glucose
31
TNF
29
ICI
27
zinc
27
bromide
25
cysteine
24
phosphate
24
phenol
20
manganese
20
NADH
19
pyridine
19
galactose
19
NAD
19
potassium
19
tyrosine
19
DPN
18
alanine
18
serine
17
4-phenyl-1,2,3,6-tetrahydropyridine
17
Clin
16
Estrogen
16
ADP
15
Estrogen
15
ADP
14
noradrenaline
14
5-HT
14
ADP
14
DHBA
14
cyanide
13
MEK
13
retinoic acid
13
Dopamine
13
1H-pyrazole
13
1H-pyrazole
13
Estradiol
12
ACS
12
N-acetylcysteine
12
ACS
12
His
12
L-DOPA
12
DAT
12
Insulin
11
lysine
11
ethanol
11
methionine
11
copper
10
nitrogen
10
sulfate
10
TEA
10
GABA
10
nicotinamide
10
GABA
10
TEA
10
MPDP
9
ubiquinol
9
PEG
9
leucine
8
more...