Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.64 (
MPP
)
1,876
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MPP
1715
Mol
194
caspase-3
158
Sep
139
tyrosine hydroxylase
138
Bcl-2
103
ATP
97
synuclein
67
estrogen receptor
67
GSH
60
cytochrome c
60
superoxide dismutase
54
dopamine transporter
53
ROS
43
peptidase
41
PI3K
37
endoplasmic reticulum
36
catalase
36
alpha-synuclein
35
MAO-B
35
lactate dehydrogenase
34
cytochrome
34
ERK1
34
tumor necrosis factor
32
nitric oxide synthase
31
p53
30
ERK
30
inducible nitric oxide synthase
30
PPT
29
TNF
29
lipopolysaccharide
28
p38
28
OCT1
28
AKT
27
LC3
27
heme oxygenase-1
26
SOD
25
mTOR
25
insulin
24
glutathione peroxidase
24
more...
Disease
Parkinson's disease
846
neuroblastoma
153
parkinsonism
93
GSH
60
Alzheimer's disease
54
cancer
32
pheochromocytoma
20
tumor
18
movement disorder
15
depression
15
ischemia
12
breast cancer
10
stroke
10
Friedreich's ataxia
8
tetanus
8
SDS
7
MCF
7
abdominal aortic aneurysm
6
Mycoplasma
6
Pineal
6
dementia
6
OPA1
6
NAME
6
cerebral ischemia
6
AAA
6
Huntington's disease
6
dyskinesia
6
pneumonia
6
diabetes
6
Blocking
5
hypertension
5
osteoporosis
5
amyotrophic lateral sclerosis
5
PPP
5
THC
5
lymphoma
4
B-cell lymphoma
4
glioma
4
Cannabis
4
erythropoietic protoporphyria
4
more...
Symptom
collapse
16
bradykinesia
9
tremor
7
hypothermia
5
starvation
4
functional recovery
3
seizures
3
acidity
3
fatigue
3
pain
2
weakness
2
exhaustion
2
ataxia
1
anesthesia
1
muscle rigidity
1
constipation
1
sinus pressure
1
thinning
1
chorea
1
diarrhea
1
stigma
1
cerebellar ataxia
1
motor symptom
1
Scratch
1
hypotonia
1
nausea and vomiting
1
discomfort
1
Drug
ROS
43
ICI
27
NADH
19
Parkin
16
Parkin
16
EE2
12
lysine
10
Ringer's solution
9
caffeine
8
FAD
6
ascorbate
6
MAP
5
Estrogens
3
CFT
3
Glutathione
3
Heme
3
CSF
3
Reserpine
3
BH4
3
vitamin E
3
EPA
3
Gel
2
Pramipexole
2
SPP
2
Pramipexole
2
Myricetin
2
ENT
2
Leaf
2
Gefitinib
2
MDS
2
Rosiglitazone
2
5-Nitroindazole
1
6-Nitroindazole
1
Ouabain
1
TAT
1
Fructose
1
Oxaliplatin
1
Bupleurum root
1
Asoprisnil
1
Salicylate
1
more...
Enzyme
MPP
1876
caspase-3
136
tyrosine hydroxylase
134
complex I
122
mitogen-activated protein kinase
97
superoxide dismutase
76
monoamine oxidase
50
ERK
40
catalase
39
protein kinase
37
lactate dehydrogenase
35
luciferase
28
glutathione peroxidase
24
MEK
22
caspase-9
22
PARP
21
GSK
21
diaphorase
19
proteasome
18
AMP-activated protein kinase
17
ATPase
15
MIP
15
focal adhesion kinase
14
ACS
13
phosphatidylinositol 3-kinase
13
NQO1
12
DAT
12
NO synthase
12
succinate dehydrogenase
11
ATP synthase
11
CPR
10
protein kinase C
9
NADH dehydrogenase
9
AMPK
9
peroxidase
9
NADPH oxidase
8
NOS
8
calcineurin
8
NADPH oxidase
8
AMPK
8
more...
Compound
MPP
1715
MPP
1715
MPTP
396
oxygen
270
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
237
Dec
123
DNA
112
ATP
97
iron
70
GSH
62
GSH
62
calcium
61
MTT
58
nitric oxide
57
1-Methyl-4-phenylpyridinium
47
glutamate
44
sodium
40
NAD
37
arginine
35
water
35
hydrogen
35
4-phenylpyridine
32
iodine
32
glucose
31
TNF
29
ICI
27
zinc
27
bromide
25
phosphate
24
cysteine
24
phenol
20
manganese
20
tyrosine
19
galactose
19
pyridine
19
potassium
19
NADH
19
NAD
19
DPN
18
alanine
18
more...