Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.59 (MIP)
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Human Gene/Protein
IGSF22 12.7
MIP 12.7
GOLT1B 12.7
ChemR13 12.7
mitochondrial intermediate peptidase 11.9
SCYA18 11.7
Hereditary hemochromatosis protein 11.7
C-C CKR-1 11.7
C3orf26 11.7
Paralemmin-3 11.7
CCDC43 11.7
LD78 11.6
CD99 antigen-like 2 11.1
SCFV 11.1
TAFA2 11.1
ZNF84 11.1
aquaporin 6 11.1
CRYBB3 10.9
CRYGC 10.7
Chemokine (C-C motif) ligand 3 10.7
SPT7L 10.7
MIP4 10.7
TPRA40 10.7
UGD 10.7
MC-CPA 10.7
CRYGS 10.4
MCAF 10.4
4EBP2 10.3
FAM19A2 10.3
MAPK organizer 1 10.3
GBP-5 10.3
macrophage inflammatory protein 3 10.3
I309 10.3
CRYBA2 10.3
TECK 10.3
CRYBB1 10.3
CRYGA 10.2
MIWC 10.2
FGF-13 10.2
putative chemokine receptor 10.2
HCC-1 10.2
ornithine decarboxylase antizyme 3 10.1
TMEM66 10.1
LILRB5 10.1
DEFB29 10.1
Fanconi anemia, complementation group A 10.1
CRYAA 10.0
MIP-3beta 9.9
LEP503 9.9
MIP3 9.9
protein kinase C, epsilon 9.9
ZNF683 9.9
CKR-1 9.9
OAZ3 9.9
Eotaxin 9.8
MIP2 9.8
NIP 9.8
CCL23 9.7
CKR1 9.7
GCP-2 9.7
SNIP 9.7
TBC1D9 9.7
PYROXD1 9.7
ALPPL2 9.7
CCL3 9.7
phakinin 9.6
CRYBA1 9.6
MCP-1 9.6
MIP-1beta 9.6
CCL15 9.6
CD83 protein 9.5
Rho guanine nucleotide exchange factor 10 9.5
RANTES 9.4
CCL4 9.4
chemokine (C-C motif) ligand 3 9.4
CXCL2 9.4
RANTES chemokine 9.3
PS21 9.3
ITAC 9.3
RANTES) 9.3
more...
Disease
Adenoviral keratitis 12.7
MIP 12.6
ASD1 10.1
Acute and chronic colitis 9.9
ASD2 9.5
ACS II 9.5
Enzootic abortion 9.3
Simian hemorrhagic fever 8.9
Corneal infection 8.8
Heaves 8.5
Stromal keratitis 8.4
Colovesical fistula 8.3
Neuroinfections 8.3
Mild depression 8.2
bacterial colitis 8.2
CPAF 8.1
Russian spring-summer encephalitis 8.1
Aspergillus flavus infection 8.0
Abdominal sepsis 8.0
lithopedion 7.9
Klebsiella pneumoniae infection 7.9
Ocular myasthenia 7.8
MPS IVB 7.7
LIP 7.7
phagocytic dysfunction 7.7
CCL 7.5
Idiopathic pneumonia syndrome 7.5
Escherichia coli pneumonia 7.5
AD5 7.5
infectious meningitis 7.4
Diffuse alveolar damage 7.2
AIP 7.1
AIP 7.0
Chronic arthritis 6.9
Legionella pneumophila pneumonia 6.7
Omsk hemorrhagic fever 6.7
Neovascular age-related macular degeneration 6.6
Familial hypocalciuric hypercalcemia 6.6
Post-kala-azar dermal leishmaniasis 6.6
HMSN I 6.5
Influenza A virus infection 6.4
Avian infectious bronchitis 6.4
CCV 6.3
SSD 6.3
AD8 6.3
polioencephalomyelitis 6.3
polyarticular arthritis 6.2
Herpesvirus infection 6.2
Clonal evolution 6.2
Klebsiella infection 6.2
endotheliosis 6.2
Oxygen toxicity 6.1
rectal polyp 6.1
Posterior capsule opacification 6.1
pulmonary granuloma 6.0
Acute pyelonephritis 6.0
Intestinal ischemia 5.9
Acute mountain sickness 5.9
loiasis 5.9
Invasive pulmonary aspergillosis 5.9
Oppenheim 5.8
BDC 5.8
Pseudomonas infection 5.8
Transfusion-related acute lung injury 5.7
Plasmacytoma 5.6
EME 5.6
hepatosis 5.6
ocular herpes 5.5
Hemorrhagic fever with renal syndrome 5.4
vaginal infection 5.4
RSV infection 5.4
Acanthamoeba keratitis 5.4
Alcoholic liver disease 5.4
HMSN I 5.4
DIP 5.3
anthracosis 5.3
Streptococcus pneumoniae meningitis 5.3
small airways disease 5.3
Candida albicans infection 5.3
pneumonic plague 5.3
more...
Symptom
cardiovascular disability 8.9
Moderate pain 8.6
POA 6.9
Gasping 6.8
itchy nose 6.7
Ear swelling 6.7
adipsia 5.1
orthopnea 3.8
Respiratory symptoms 3.8
hyperoxia 3.8
hyperesthesia 3.6
ataxic gait 3.6
limb pain 3.3
CSR 3.2
respiratory distress 3.2
HSA 3.1
dry eye 2.9
neurological disability 2.8
sneezing 2.8
functional recovery 2.8
dry skin 2.7
microbial colonization 2.6
Postoperative pain 2.6
wheezing 2.4
Neuropathic pain 2.2
bone pain 2.1
exertional dyspnea 1.9
alexithymia 1.9
hypothermia 1.9
erythema 1.8
exhaustion 1.7
Depressive symptoms 1.7
chronic cough 1.7
blurred vision 1.6
chills 1.6
dyspnea 1.6
flank pain 1.6
rhinorrhea 1.5
weakness 1.5
arthralgia 1.4
splenomegaly 1.4
tachypnea 1.4
Wind 1.3
hypercapnia 1.3
fatigue 1.3
cough 1.1
polyuria 1.1
myalgia 1.0
epigastric pain 0.9
memory loss 0.8
pelvic pain 0.7
low back pain 0.4
numbness 0.3
shortness of breath 0.3
ataxia 0.3
Ill 0.2
thinning 0.2
cachexia 0.2
collapse 0.2
paresis 0.2
hypotonia 0.1
pain 0.1
tremor 0.1
vomiting 0.0
flushing 0.0
spasticity 0.0
overweight -0.0
anorexia -0.1
analgesia -0.1
vertigo -0.1
syncope -0.5
diarrhea -0.6
nausea and vomiting -0.6
constipation -0.7
anesthesia -0.8
nausea -0.9
agitation -0.9
back pain -0.9
sleepiness -1.0
stigma -1.0
more...
Drug
Propionamide 9.2
Tacalcitol 8.5
Myozyme 7.8
IL-1ra 7.5
CCL 7.5
E5564 7.5
G-CSF 7.3
Ortho Tri-Cyclen 7.3
Iomeprol 7.2
Peridinin 7.2
Flunisolide 7.1
Butaprost 6.7
Dextran sulfate sodium 6.6
IL-11 6.4
Mepolizumab 6.3
Omniscan 6.3
Mizoribine 6.1
Hydroxyethylstarch 6.0
Fluticasone propionate 5.8
BTC 5.8
Pirfenidone 5.8
KGF 5.8
CSF 5.7
Pepstatin 5.7
Sulprostone 5.7
Anakinra 5.7
Roflumilast 5.6
Roflumilast 5.6
Omniscan 5.6
IL-2 5.5
Vinpocetine 5.5
Human Serum Albumin 5.4
Rebamipide 5.4
PMPA 5.4
CTA 5.4
IFN-gamma 5.2
Enfuvirtide 5.2
Fenoldopam 5.1
Maraviroc 5.1
Dextrose 5.0
Rifaximin 5.0
Olmesartan 5.0
NOV 4.9
PE2 4.9
DEX 4.8
DFP 4.8
CEC 4.8
Fenoterol 4.8
OIF 4.7
Iopamidol 4.7
Clodronate 4.7
Cidofovir 4.6
IFN-beta 4.6
Fondaparinux 4.3
Ergosterol 4.3
TAK 4.3
Lovastatin 4.3
DEL 4.3
Artesunate 4.2
Caspofungin 4.2
SPP 4.1
GEO 4.1
SBT 4.0
SiO2 4.0
Omalizumab 4.0
Tenofovir 4.0
CTT 4.0
CPR 3.9
Bosentan 3.9
Bosentan 3.9
Tocilizumab 3.9
Rolipram 3.9
Timolol 3.9
Oxaliplatin 3.8
ISP 3.8
Cibacron Blue 3.8
MTC 3.7
Imiquimod 3.6
Infliximab 3.5
Infliximab 3.5
more...
Enzyme
MIP 12.7
oligopeptidase A 9.2
L-amino-acid oxidase 7.5
granzyme K 7.2
m-AAA protease 7.1
FTR 6.9
myo-inositol-1-phosphate synthase 6.7
C5a peptidase 6.4
STK2 6.1
hydroxyprostaglandin dehydrogenase 6.0
ceramide kinase 5.9
BAL 5.9
TSP-1 5.7
MPP 5.7
homoserine kinase 5.6
STK 5.4
SLB 5.4
pyroglutamate aminopeptidase 5.3
ScpA 5.2
NAO 5.2
carboxypeptidase G2 5.2
kynureninase 5.1
carboxypeptidase E 5.0
thimet oligopeptidase 5.0
lambda exonuclease 5.0
prostate-specific membrane antigen 4.9
factor D 4.9
PRT 4.9
FAST 4.7
granzyme B 4.4
HPI 4.4
sortase A 4.4
interstitial collagenase 4.4
inositol phosphatase 4.3
PNL 4.3
ornithine transcarbamylase 4.2
Der p 1 4.2
IKK 4.2
neuropathy target esterase 4.2
matrix metalloproteinase 9 4.1
PME 4.1
MEKK1 4.1
MAT 4.1
GRK5 4.1
AST 4.1
cathepsin C 4.1
methylmalonyl-CoA mutase 4.0
neutrophil elastase 4.0
succinyl-CoA synthetase 4.0
MMP-3 3.9
cruzipain 3.9
Protein 2 3.9
GRK2 3.9
MAT 3.9
lactic acid dehydrogenase 3.8
lactonase 3.8
lactic acid dehydrogenase 3.8
mitogen-activated protein kinase 3.8
glucosylceramide synthase 3.8
peroxidase 3.7
cathepsin S 3.7
RNase 3.7
RNase 3.6
MAP 3.6
proteasome 3.6
p80 3.6
ADPase 3.6
HK2 3.5
matrix metalloproteinase 2 3.5
15-lipoxygenase 3.5
serine hydroxymethyltransferase 3.5
cathepsin K 3.4
arylsulfatase A 3.4
arginase 3.4
cysteine synthase 3.4
15-hydroxyprostaglandin dehydrogenase 3.4
SPC 3.3
alanine aminotransferase 3.3
neutral sphingomyelinase 3.3
chymase 3.3
more...
Compound
5-methylisophthalic acid 11.5
4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid 11.1
4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid 11.1
Tuberostemonine 10.1
Vestitol 9.2
9-vinylanthracene 9.0
2,5-thiophenedicarboxylic acid 9.0
5-aminoisophthalic acid 9.0
Boc-phenylalanine 8.9
1-chlorohexadecane 8.8
L-Phenylalanine, 8.7
Forsythiaside 8.7
MEP 8.5
MIPC 8.5
Isofraxidin 8.4
MEP 8.4
Decursinol 8.3
Methylenebisacrylamide 8.3
TMTU 8.3
A 174 8.3
1,4-cyclohexanedicarboxylic acid 8.3
1,4-cyclohexanedicarboxylic acid 8.3
Allylthiourea 8.1
Pirimicarb 8.1
Solanine 8.0
4-aminobenzamide 7.9
L-Phenylalanine, 7.8
3-hydroxyhexadecanoic acid 7.8
Solanine 7.8
DNBA 7.8
4-vinylpyridine 7.6
5-hydroxyisophthalic acid 7.6
Metanephrine 7.6
5-hydroxyisophthalic acid 7.6
1,3,5-benzenetricarboxylic acid 7.6
Pentachlorobenzene 7.5
Neocuproine 7.5
Allylamine 7.4
MCP 7.3
Mimosine 7.3
Mimosine 7.2
LXB4 7.1
Flunisolide 7.1
4-hydroxyphenylarsonic acid 7.1
Betanin 7.0
Tetrahydrocurcumin 7.0
2-methoxybenzoic acid 7.0
1,3,5-trichlorobenzene 6.8
Pulegone 6.8
methylarsonic acid 6.8
Stigmasterol 6.8
L-chicoric acid 6.7
Tragacanth 6.7
Diprotin A 6.6
HMDI 6.6
tetramethyl orthosilicate 6.5
Glabridin 6.5
Geranylgeranylacetone 6.5
Zingerone 6.4
TNF 6.3
2-vinylpyridine 6.3
2-vinylpyridine 6.3
2-vinylpyridine 6.3
Nalmefene 6.3
Methacrylic acid 6.3
POA 6.3
Calcein AM 6.3
Mandelate 6.2
phenylphosphonic acid 6.1
Dioscin 6.1
Dioscin 6.1
CHIP 6.1
pentanedioic acid 6.1
phenylphosphonic acid 6.1
Jasplakinolide 6.0
Nefazodone 6.0
arsenic acid 6.0
arsenic acid 6.0
arsenic acid 6.0
arsenic acid 6.0
more...