Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.59 (
MIP
)
4,906
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MIP
4876
cytokine
1061
chemokine
996
IL-6
877
MCP-1
848
TNF
762
RANTES
645
IL-8
589
IL-10
456
IFN
392
CXCL10
330
Sep
319
TNF-alpha
310
lipopolysaccharide
280
IL-4
255
Mol
249
tumor necrosis factor
246
MIP-1alpha
240
LPS
233
GM-CSF
225
IL-2
205
IL-17
199
CCL3
187
CCR5
167
IL-13
164
IFN-gamma
163
CD4
163
CCL2
157
TLR4
156
interferon
154
Cytokine
152
G-CSF
142
IL-1
132
IL-5
129
tumor necrosis factor alpha
128
myeloperoxidase
122
CCL4
122
VEGF
120
p38
119
CD8
116
MIP-1beta
116
ICAM-1
113
eotaxin
112
RANTES)
109
monocyte chemoattractant protein-1
109
CXCL2
108
CXCL1
105
inducible nitric oxide synthase
100
C-C
94
MCP-3
91
GRO
89
MAPK
89
CCL20
88
IL-1 beta
87
CCR1
85
CXCR2
84
CXCL9
84
monocyte chemotactic protein
83
interleukin-6
80
CC chemokine
79
TLR2
79
IL-7
78
IL-15
77
CXC chemokine
77
monocyte chemoattractant protein
76
chemokine receptor
71
CD11b
70
collagen
68
Eotaxin
66
insulin
66
macrophage colony-stimulating factor
64
THP
63
vascular endothelial growth factor
62
interferon-gamma
60
p65
59
ERK1
59
IL-18
59
MEP
58
CD14
58
NIP
57
more...
Disease
MIP
4876
tumor
235
HIV
202
cancer
197
sepsis
101
sepsis
98
pneumonia
75
ischemia
75
immunodeficiency
72
infectious diseases
65
asthma
64
influenza
58
AIDS
55
virus infection
55
rheumatoid arthritis
54
diabetes
53
SEM
52
arthritis
48
tuberculosis
47
chronic obstructive pulmonary disease
46
multiple sclerosis
45
Mycobacterium
45
Infection
44
tumor growth
43
leukemia
41
carcinoma
38
obesity
38
colitis
37
CCL
36
cornea
35
multiple myeloma
35
pertussis
34
Alzheimer's disease
33
inflammatory bowel disease
33
encephalomyelitis
33
breast cancer
32
peritonitis
31
stroke
30
pulmonary edema
30
bacterial infection
29
melanoma
28
atherosclerosis
27
cataract
27
malaria
26
plaque
25
lung cancer
25
lung disease
24
lymphoma
23
colorectal cancer
22
metastases
21
keratitis
21
viremia
20
Klebsiella
20
tumor progression
19
GSH
19
cardiovascular disease
19
herpes simplex
19
cold
19
dengue
18
tumorigenesis
18
cystic fibrosis
18
depression
18
meningitis
17
prostate cancer
17
LIP
16
Blocking
16
cytomegalovirus
16
glomerulonephritis
15
COPD
15
autoimmune disease
15
Chlamydia
15
HGF
15
hypertension
15
hepatocellular carcinoma
15
periodontitis
14
adenocarcinoma
14
RSV infection
14
bone disease
14
liver disease
14
hepatitis C
14
more...
Symptom
pain
43
respiratory distress
27
fatigue
19
weakness
16
functional recovery
14
dyspnea
13
hyperoxia
11
anesthesia
10
POA
10
hypothermia
10
cough
8
erythema
7
exhaustion
7
diarrhea
6
vomiting
5
collapse
5
wheezing
4
analgesia
4
splenomegaly
4
headache
4
overweight
4
seizures
4
HSA
4
dry eye
3
arthralgia
3
ataxia
3
tremor
3
hypercapnia
3
bone pain
2
myalgia
2
sneezing
2
abdominal pain
2
chills
2
exertional dyspnea
2
nausea
2
low back pain
2
anorexia
2
Ill
2
thinning
2
Gasping
1
sleepiness
1
limb pain
1
hyperesthesia
1
Postoperative pain
1
memory loss
1
paresis
1
vertigo
1
adipsia
1
polyuria
1
Respiratory symptoms
1
Neuropathic pain
1
cachexia
1
flank pain
1
rhinorrhea
1
Ear swelling
1
tachypnea
1
stigma
1
hypotonia
1
discomfort
1
spasticity
1
starvation
1
orthopnea
1
CSR
1
blurred vision
1
alexithymia
1
itchy nose
1
epigastric pain
1
pelvic pain
1
syncope
1
dry skin
1
neurological disability
1
shortness of breath
1
Moderate pain
1
nausea and vomiting
1
agitation
1
numbness
1
constipation
1
back pain
1
Depressive symptoms
1
discomfort
1
more...
Drug
CSF
256
IL-2
205
IFN-gamma
160
G-CSF
132
IL-1ra
39
CCL
36
Dermatol
25
ROS
23
MAP
16
SiO2
15
IL-11
15
lysine
12
IFN-beta
11
caffeine
9
CTA
9
Asthma
9
ROC
9
TiO2
9
PTH
7
Asn
7
PMPA
5
CEC
5
ascorbate
5
Monit
5
Cardiovasc
5
Leaf
5
BTC
5
p75
5
Albumin
4
Glycerol
4
DFP
4
CTX
4
CPR
4
Bifidobacterium
4
EE2
4
Lovastatin
4
DEX
4
KGF
4
GEO
4
ZnO
4
Kenyan
3
vitamin E
3
Gelatin
3
Silica
3
MOF
3
TAK
3
Heme
2
AZT
2
Fragment
2
PTC
2
Activin
2
Dextrose
2
Histamine
2
uPA
2
Oxaliplatin
2
CTX
2
NADH
2
Ringer's solution
2
AZT
2
Infliximab
2
Indomethacin
2
DNase I
2
Infliximab
2
Biopolymers
2
lactose
2
CTX
2
DM1
2
Fluorescein
2
Nephron
2
Theophylline
2
Anakinra
2
L-tyrosine
2
VCR
2
ENT
2
Taxol
2
ampicillin
2
Pirfenidone
2
Ethanol
2
Etoposide
1
Myozyme
1
more...
Enzyme
MIP
4906
mitogen-activated protein kinase
200
peroxidase
131
ERK
90
proteasome
53
reverse transcriptase
41
alanine aminotransferase
40
RNase
34
RNase
32
lysozyme
29
superoxide dismutase
28
protein kinase
28
lactate dehydrogenase
27
luciferase
26
protein kinase C
26
collagenase
25
aspartate aminotransferase
25
MEK
22
caspase-3
22
catalase
22
NO synthase
21
ACS
21
BAL
18
focal adhesion kinase
17
AST
16
MPP
15
MAP
14
IKK
14
trypsin
13
PARP
13
elastase
12
NADPH oxidase
11
granzyme B
11
APC
11
NADPH oxidase
10
neutrophil elastase
10
caspase-1
9
ribonuclease
8
ribonuclease
8
phospholipase C
8
alkaline phosphatase
8
creatine kinase
8
MMP-3
8
prostate-specific membrane antigen
8
AMP-activated protein kinase
8
phosphatidylinositol 3-kinase
7
ATPase
7
thrombin
7
NOS
7
TSP-1
7
CPR
6
matrix metalloproteinase 9
6
arginase
6
tissue plasminogen activator
6
MMP
6
glutathione peroxidase
6
AMPK
6
beta-galactosidase
5
MEKK1
5
phosphodiesterase
5
acid phosphatase
5
heme oxygenase
5
hexosaminidase
5
urokinase-type plasminogen activator
5
ornithine transcarbamylase
5
acetylcholinesterase
4
adenosine deaminase
4
adenosine deaminase
4
adenylate cyclase
4
matrix metalloproteinase 2
4
SPC
4
lipase
4
MAT
4
calcineurin
4
MAT
4
cholinesterase
4
lipoxygenase
3
pepsin
3
cathepsin K
3
hypoxanthine-guanine phosphoribosyltransferase
3
more...
Compound
TNF
762
Dec
324
water
283
DNA
195
Clin
148
calcium
124
oxygen
121
nitric oxide
93
PEG
85
PEG
81
glucose
64
sodium
64
THP
63
THP
63
MEP
58
MEP
58
phosphate
53
MCP
49
hydrogen
47
iron
46
methanol
43
tyrosine
43
acrylamide
42
ethanol
42
urea
39
glycerol
37
nitrogen
36
sulfate
35
cysteine
32
acetonitrile
32
acetate
31
Phe
31
PMA
28
4-vinylpyridine
27
lysine
27
PMA
27
cAMP
27
vinyl
26
creatinine
26
arginine
24
alanine
24
zinc
23
MDA
23
leucine
22
ACS
22
salt
22
acetic acid
22
ammonium
22
tryptophan
21
toluene
21
PGE
21
galactose
21
ACS
21
TOF
20
GSH
19
BAL
19
GSH
19
His
18
methionine
18
titanium
17
NH2
17
SiO2
17
Asp
17
PGE2
17
tryptophan
16
tryptophan
16
N-acetylcysteine
16
copper
16
NKT
16
tryptophan
16
MAP
15
H2O2
15
ATP
15
CO2
14
serine
14
silver
13
thioglycollate
13
SDS
13
TEM
12
Dexamethasone
12
more...