Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.4.24.59 (MIP)
 4,906 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study was carried out to evaluate time-of-flight RA in renal artery stenosis (RAS) in selected hypertensive patients (n = 41). In i.a. DSA studies, 10 unilateral, 8 bilateral RAS, and 4 unilateral RA occlusions were proven. MRA was done in coronal and axial 2D technique (FLASH), and in 3D technique (FISP) using GE-pulse sequences. DSA results were correlated with both 2D-individual slices, 2D- and 3D-MIP angiograms. Highest sensitivity and specificity was found for the axial 2D individual slice analysis (88%, 85% resp.), followed by the 3D-MIP MRA (78%, 80% resp.), and axial 2D-MIP MRA (73%, 79% resp.). MRA of renal arteries used in this study shows to be not adequate to DSA results due to many drawbacks. All MRA techniques, in particular the 3D-technique, tend to overestimate RAS occasionally pretending occlusions.
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PMID:[The evaluation of 2D- and 3D-"time of flight" magnetic resonance angiography (MRA) in the diagnosis of renal artery stenoses]. 163 7

Spiral CT in the form of CT angiography (CTA) provides a new method for the investigation of the large vessels. 52 patients with suspected renovascular hypertension were examined by CTA and arterial DSA. The computer tomographic and angiographic findings in 124 renal arteries were compared. Sensitivity of CTA for demonstrating renal artery stenosis was 95%, and for relevant stenoses it actually reached 100%. Specificity was 92%. Positive/negative prediction value was 85% and 100%. CTA proved outstandingly good for demonstrating or excluding renal artery stenosis and was superior to other imaging methods in several respects. CTA requires high contrast values, optimal timing and careful evaluation. Amongst various forms of image reconstruction, interactive viewing of the primary axial images and multiplanar reconstruction in a cine mode are essential and MIP projections are valuable.
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PMID:[Accuracy of CT angiography in the diagnosis of renal artery stenosis]. 780 75

With the recent advent of spiral or helical CT, the ability to acquire large volume of imaging has become possible. Fast scanning of both kidneys, the aorta and the renal vessels can be accomplished during one breathhold. Early reports of CT angiography in the evaluation of renal artery stenosis indicated a sensitivity of 92% utilizing the MIP projection method and 59% utilizing the shaded surface display method. Specificity for both method was approximately 82%. More recent articles reports for hemodynamically relevant renal artery stenosis a sensitivity/sensibility of 96/99%. The introduction of a new multidetector CT technology will probably increase those results and the indication of CT angiography.
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PMID:[Spiral computed tomography of the renal arteries]. 1052 19