EC:3.4.24.56 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: EC:3.4.24.56 (insulin-degrading enzyme)
737 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
hNRD2	15.4
insulysin	15.4
insulinase	15.4
insulin-degrading enzyme	15.2
myosin XVI	13.4
PreP	13.0
HHEX	12.8
alphaT-catenin	12.7
NRDC	12.7
PPP1R5	12.6
UBE2J1	12.1
LRRTM3	12.1
nardilysin	11.9
vesicle trafficking protein	11.8
CDKAL1	11.7
MYO16	11.7
VPS26A	11.5
APBB2	11.5
SORCS1	11.4
SLC30A8	11.4
ECE2	11.3
gene/pseudogene	11.3
ECE-2	11.3
glutathione-insulin transhydrogenase	11.3
kuzbanian	11.2
NADH pyrophosphatase	11.2
M-BAR	11.2
Nardilysin	11.1
GABRE	11.1
CAMK1D	11.0
phosphatidylinositol binding clathrin assembly protein	10.9
flotillin 1	10.9
PPARGC1	10.9
A14	10.8
metalloprotease 1	10.8
ARAP1	10.7
N-arginine dibasic convertase	10.7
ADDL	10.7
IGF2BP2	10.7
WNT8B	10.6

Disease
Cerebrovascular amyloidosis	12.6
Sporadic cerebral amyloid angiopathy	11.9
Advanced cancer	8.6
Neurodegenerative Disorders	8.3
EXT2	7.8
INS	7.7
APOA1	7.3
DM2	7.2
BED	7.1
biventricular failure	6.9
APOB	6.8
Alzheimer's disease	6.7
denticles	6.5
degenerative disc disease	6.5
cognitive disorder	6.4
TBS	6.3
MTC	6.3
LDLR	6.3
hyperinsulinemia	6.2
Habituation	6.2
corneal dystrophy	6.0
PNET	5.9
memory impairment	5.9
PCS	5.9
cowpox	5.7
tinea capitis	5.6
PAM	5.6
DMS	5.4
Testis	5.4
Testis	5.4
glucose intolerance	5.3
type 2 diabetes	5.3
diabetic foot ulcers	5.3
varicella	5.3
Johne's disease	5.2
cholecystolithiasis	5.1
insulinoma	5.1
cognitive impairment	5.0
skin infection	5.0
senile dementia	4.8

Enzyme
EC 3.4.24.54	15.4
insulin-degrading enzyme	15.4
IDS3	12.4
glutathione-insulin transhydrogenase	12.2
nardilysin	12.2
IDS2	12.2
NADH pyrophosphatase	11.5
endothelin-converting enzyme	10.5
PTR	10.3
polysaccharide deacetylase	9.9
neurolysin	9.8
thimet oligopeptidase	9.3
CD10	9.0
beta-secretase	8.6
tripeptidyl peptidase	8.3
transhydrogenase	7.9
KLK7	7.9
aminopeptidase B	7.6
inositol 3-kinase	7.5
thermolysin	6.8
endoproteinase Glu-C	6.7
choline kinase	6.6
MPP	6.5
lysyl endopeptidase	6.4
PTPase	6.4
SMP	6.0
cathepsin D	6.0
plasmin	6.0
cathepsin B	6.0
TPP	5.9
fructose 1,6-bisphosphatase	5.8
prolyl endopeptidase	5.8
PAM	5.5
acyl-CoA oxidase	5.5
cathepsin L	5.5
proteasome	5.4
furin	5.3
neuropathy target esterase	5.3
TPP	5.1
GSK	5.0