EC:3.4.24.35 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: EC:3.4.24.35 (matrix metalloproteinase 9)
2,207 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
matrix metalloproteinase 9	1107
MMP9	537
matrix metalloproteinase 2	531
MMP-9	484
matrix metalloproteinase	328
collagen	303
MMP-2	252
Mol	171
metalloproteinase	148
collagenase	147
MMP-1	137
EPA	137
Sep	135
stromelysin	134
MMP-3	113
MMP	107
TIMP-2	102
cytokine	96
tumor necrosis factor	91
vascular endothelial growth factor	84
fibronectin	79
tissue inhibitor of metalloproteinases	67
TNF	59
lipopolysaccharide	58
matrilysin	54
urokinase-type plasminogen activator	53
IL-6	52
E-cadherin	48
IL-8	47
cathepsin K	45
plasminogen	44
chemokine	39
AP-1	39
p38	37
elastin	37
insulin	36
ERK1	35
TIMP	35
VEGF	34
TNF-alpha	34
epidermal growth factor	34
MMP-13	34
type I collagen	34
p65	34
MMP-8	31
ERK	30
collagenase-3	30
caspase-3	30
MAPK	29
THP	29
tissue inhibitor of metalloproteinase 1	29
tartrate-resistant acid phosphatase	28
MMP2	28
PLA	28
extracellular signal-regulated kinase	26
inducible nitric oxide synthase	26
MMP-7	26
RANKL	25
superoxide dismutase	25
LPS	24
tumor necrosis factor alpha	24
p53	24
AKT	24
neutrophil elastase	23
myeloperoxidase	23
epidermal growth factor receptor	23
osteosarcoma	22
catenin	22
interleukin-6	22
TIMP-3	20
casein	20
CD44	20
cyclin D1	20
MT1-MMP	20
vimentin	20
EGF	19
SDS	19
TGF-beta	19
proliferating cell nuclear antigen	19
platelet-derived growth factor	19

Disease
tumor	432
cancer	400
carcinoma	96
metastases	95
breast cancer	92
tumor growth	66
stroke	64
tumor progression	60
melanoma	47
rheumatoid arthritis	42
atherosclerosis	41
diabetes	41
multiple sclerosis	38
prostate cancer	36
carcinogenesis	34
tumorigenesis	33
ischemia	33
plaque	33
MCF	29
fibrosarcoma	27
squamous cell carcinoma	27
hypertension	26
adenocarcinoma	26
osteosarcoma	24
myocardial infarction	24
Alzheimer's disease	24
chronic obstructive pulmonary disease	24
arthritis	23
osteoporosis	22
hepatocellular carcinoma	22
colorectal cancer	22
gastric cancer	20
asthma	20
brain edema	19
lung cancer	19
primary tumor	19
SDS	19
leukemia	19
cerebral ischemia	18
cornea	17
colon cancer	17
sepsis	17
glioma	16
sepsis	16
pancreatic cancer	14
tumor angiogenesis	14
pulmonary fibrosis	14
uterus	13
abdominal aortic aneurysm	13
autoimmune disease	13
ovarian cancer	13
obesity	13
encephalomyelitis	13
aggressiveness	12
liver fibrosis	12
non-small cell lung cancer	12
astrocytoma	12
osteoarthritis	11
periodontitis	11
emphysema	11
meningitis	11
Evans	10
Blocking	10
HIV	10
heart failure	9
epithelial ovarian cancer	9
glioblastoma	9
cardiovascular disease	9
mammary tumor	8
cirrhosis	8
pemphigoid	8
pneumonia	8
coronary artery disease	8
Parkinson's disease	8
renal failure	8
lymphoma	8
idiopathic pulmonary fibrosis	8
lung metastases	8
tuberculosis	7
Epstein	7

Symptom
functional recovery	11
pain	11
anesthesia	6
respiratory distress	5
thinning	5
hyperoxia	3
seizures	3
hypothermia	3
swollen joints	2
splenomegaly	2
starvation	2
angina	2
collapse	2
dry eye	2
analgesia	2
dizziness	1
weakness	1
impaired motor coordination	1
cough	1
chest pain	1
overweight	1
ataxia	1
chronic cough	1
dystonia	1
abdominal pain	1
Central post-stroke pain	1
spasm	1
erythema	1
skin irritation	1
headache	1
acute stress	1

Enzyme
matrix metalloproteinase 9	2207
matrix metalloproteinase 2	632
collagenase	232
MMP-3	167
MMP	159
interstitial collagenase	111
mitogen-activated protein kinase	110
urokinase-type plasminogen activator	67
ERK	52
cathepsin K	45
trypsin	38
plasmin	37
luciferase	31
tissue plasminogen activator	30
peroxidase	30
elastase	29
neutrophil elastase	29
protein kinase	28
superoxide dismutase	27
protein kinase C	25
focal adhesion kinase	23
catalase	21
caspase-3	20
macrophage elastase	17
alkaline phosphatase	16
neutrophil collagenase	16
MEK	16
cathepsin G	16
acid phosphatase	15
reverse transcriptase	13
CD10	12
thrombin	12
stromelysin-3	11
glutathione peroxidase	10
cathepsin B	9
collagenase 3	9
NADPH oxidase	9
NO synthase	8
proteasome	8
cathepsin D	8
aspartate aminotransferase	8
NADPH oxidase	8
ATPase	7
phosphoinositide 3-kinase	7
phosphatidylinositol 3-kinase	7
alanine aminotransferase	7
chymase	7
MIP	6
calcineurin	6
lactate dehydrogenase	5
CD13	5
RNase	5
RNase	5
tryptase	5
TACE	4
GSK	4
renin	4
PARP	4
chymotrypsin	4
AST	4
ACS	4
beta-glucuronidase	4
IKK	3
cathepsin L	3
glutathione S-transferase	3
granzyme B	3
transcriptase	3
ribonuclease	3
carbonic anhydrase	3
ribonuclease	3
tyrosine hydroxylase	3
thermolysin	3
beta-galactosidase	3
NQO1	3
phosphorylase	3
isocitrate dehydrogenase	3
RNA polymerase	3
matrix metalloproteinase 10	3
kallikrein	3
isocitrate dehydrogenase	3