Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.35 (matrix metalloproteinase 9)
2,207 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
matrix metalloproteinase 9 1107
MMP9 537
matrix metalloproteinase 2 531
MMP-9 484
matrix metalloproteinase 328
collagen 303
MMP-2 252
Mol 171
metalloproteinase 148
collagenase 147
EPA 137
MMP-1 137
Sep 135
stromelysin 134
MMP-3 113
MMP 107
TIMP-2 102
cytokine 96
tumor necrosis factor 91
vascular endothelial growth factor 84
fibronectin 79
tissue inhibitor of metalloproteinases 67
TNF 59
lipopolysaccharide 58
matrilysin 54
urokinase-type plasminogen activator 53
IL-6 52
E-cadherin 48
IL-8 47
cathepsin K 45
plasminogen 44
AP-1 39
chemokine 39
p38 37
elastin 37
insulin 36
TIMP 35
ERK1 35
MMP-13 34
epidermal growth factor 34
more...
Disease
tumor 432
cancer 400
carcinoma 96
metastases 95
breast cancer 92
tumor growth 66
stroke 64
tumor progression 60
melanoma 47
rheumatoid arthritis 42
diabetes 41
atherosclerosis 41
multiple sclerosis 38
prostate cancer 36
carcinogenesis 34
plaque 33
ischemia 33
tumorigenesis 33
MCF 29
squamous cell carcinoma 27
fibrosarcoma 27
adenocarcinoma 26
hypertension 26
chronic obstructive pulmonary disease 24
myocardial infarction 24
Alzheimer's disease 24
osteosarcoma 24
arthritis 23
hepatocellular carcinoma 22
colorectal cancer 22
osteoporosis 22
gastric cancer 20
asthma 20
primary tumor 19
brain edema 19
SDS 19
lung cancer 19
leukemia 19
cerebral ischemia 18
cornea 17
more...
Symptom
functional recovery 11
pain 11
anesthesia 6
respiratory distress 5
thinning 5
hyperoxia 3
seizures 3
hypothermia 3
swollen joints 2
splenomegaly 2
starvation 2
angina 2
collapse 2
dry eye 2
analgesia 2
dizziness 1
weakness 1
impaired motor coordination 1
cough 1
chest pain 1
overweight 1
ataxia 1
chronic cough 1
dystonia 1
abdominal pain 1
Central post-stroke pain 1
spasm 1
erythema 1
skin irritation 1
headache 1
acute stress 1
Drug
Gelatin 42
Dermatol 35
CSF 13
uPA 12
IFN-gamma 11
lysine 10
DNase I 7
Gel 7
Cardiovasc 7
ROS 6
MAP 5
PTH 5
Asn 5
Indomethacin 5
Asthma 4
G-CSF 4
Batimastat 4
Doxycycline 4
Batimastat 4
vitamin E 3
Vitamin E 3
Amiloride 3
Amiloride 3
CaCl2 3
CaCl2 3
CaCl2 3
Simvastatin 3
p75 3
IFN-beta 3
Urokinase 2
IL-2 2
TAT 2
lactose 2
Propofol 2
Rutin 2
ID2 2
Aliskiren 2
Magnesium sulfate 1
ROC 1
Methylprednisolone 1
more...
Enzyme
matrix metalloproteinase 9 2207
matrix metalloproteinase 2 632
collagenase 232
MMP-3 167
MMP 159
interstitial collagenase 111
mitogen-activated protein kinase 110
urokinase-type plasminogen activator 67
ERK 52
cathepsin K 45
trypsin 38
plasmin 37
luciferase 31
tissue plasminogen activator 30
peroxidase 30
elastase 29
neutrophil elastase 29
protein kinase 28
superoxide dismutase 27
protein kinase C 25
focal adhesion kinase 23
catalase 21
caspase-3 20
macrophage elastase 17
MEK 16
alkaline phosphatase 16
cathepsin G 16
neutrophil collagenase 16
acid phosphatase 15
reverse transcriptase 13
thrombin 12
CD10 12
stromelysin-3 11
glutathione peroxidase 10
cathepsin B 9
collagenase 3 9
NADPH oxidase 9
proteasome 8
cathepsin D 8
NADPH oxidase 8
more...
Compound
Dec 151
Clin 95
DNA 90
acetate 88
oxygen 77
zinc 67
TNF 59
calcium 52
serine 42
water 39
MDA 34
glucose 33
nitric oxide 30
THP 29
THP 29
leucine 28
NH2 27
MTT 26
tyrosine 26
sodium 25
arginine 24
alanine 24
sulfate 23
Gly 23
lysine 22
cysteine 21
EDTA 20
Collagenase 20
EDTA 20
SDS 19
cAMP 18
PMA 15
Asp 15
Phe 15
threonine 14
PMA 14
phosphate 13
methionine 13
Cereb 13
His 12
more...