Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.24.35 (
matrix metalloproteinase 9
)
2,207
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
matrix metalloproteinase 9
1107
MMP9
537
matrix metalloproteinase 2
531
MMP-9
484
matrix metalloproteinase
328
collagen
303
MMP-2
252
Mol
171
metalloproteinase
148
collagenase
147
EPA
137
MMP-1
137
Sep
135
stromelysin
134
MMP-3
113
MMP
107
TIMP-2
102
cytokine
96
tumor necrosis factor
91
vascular endothelial growth factor
84
fibronectin
79
tissue inhibitor of metalloproteinases
67
TNF
59
lipopolysaccharide
58
matrilysin
54
urokinase-type plasminogen activator
53
IL-6
52
E-cadherin
48
IL-8
47
cathepsin K
45
plasminogen
44
AP-1
39
chemokine
39
p38
37
elastin
37
insulin
36
TIMP
35
ERK1
35
MMP-13
34
epidermal growth factor
34
more...
Disease
tumor
432
cancer
400
carcinoma
96
metastases
95
breast cancer
92
tumor growth
66
stroke
64
tumor progression
60
melanoma
47
rheumatoid arthritis
42
diabetes
41
atherosclerosis
41
multiple sclerosis
38
prostate cancer
36
carcinogenesis
34
plaque
33
ischemia
33
tumorigenesis
33
MCF
29
squamous cell carcinoma
27
fibrosarcoma
27
adenocarcinoma
26
hypertension
26
chronic obstructive pulmonary disease
24
myocardial infarction
24
Alzheimer's disease
24
osteosarcoma
24
arthritis
23
hepatocellular carcinoma
22
colorectal cancer
22
osteoporosis
22
gastric cancer
20
asthma
20
primary tumor
19
brain edema
19
SDS
19
lung cancer
19
leukemia
19
cerebral ischemia
18
cornea
17
more...
Symptom
functional recovery
11
pain
11
anesthesia
6
respiratory distress
5
thinning
5
hyperoxia
3
seizures
3
hypothermia
3
swollen joints
2
splenomegaly
2
starvation
2
angina
2
collapse
2
dry eye
2
analgesia
2
dizziness
1
weakness
1
impaired motor coordination
1
cough
1
chest pain
1
overweight
1
ataxia
1
chronic cough
1
dystonia
1
abdominal pain
1
Central post-stroke pain
1
spasm
1
erythema
1
skin irritation
1
headache
1
acute stress
1
Drug
Gelatin
42
Dermatol
35
CSF
13
uPA
12
IFN-gamma
11
lysine
10
DNase I
7
Gel
7
Cardiovasc
7
ROS
6
MAP
5
PTH
5
Asn
5
Indomethacin
5
Asthma
4
G-CSF
4
Batimastat
4
Doxycycline
4
Batimastat
4
vitamin E
3
Vitamin E
3
Amiloride
3
Amiloride
3
CaCl2
3
CaCl2
3
CaCl2
3
Simvastatin
3
p75
3
IFN-beta
3
Urokinase
2
IL-2
2
TAT
2
lactose
2
Propofol
2
Rutin
2
ID2
2
Aliskiren
2
Magnesium sulfate
1
ROC
1
Methylprednisolone
1
more...
Enzyme
matrix metalloproteinase 9
2207
matrix metalloproteinase 2
632
collagenase
232
MMP-3
167
MMP
159
interstitial collagenase
111
mitogen-activated protein kinase
110
urokinase-type plasminogen activator
67
ERK
52
cathepsin K
45
trypsin
38
plasmin
37
luciferase
31
tissue plasminogen activator
30
peroxidase
30
elastase
29
neutrophil elastase
29
protein kinase
28
superoxide dismutase
27
protein kinase C
25
focal adhesion kinase
23
catalase
21
caspase-3
20
macrophage elastase
17
MEK
16
alkaline phosphatase
16
cathepsin G
16
neutrophil collagenase
16
acid phosphatase
15
reverse transcriptase
13
thrombin
12
CD10
12
stromelysin-3
11
glutathione peroxidase
10
cathepsin B
9
collagenase 3
9
NADPH oxidase
9
proteasome
8
cathepsin D
8
NADPH oxidase
8
more...
Compound
Dec
151
Clin
95
DNA
90
acetate
88
oxygen
77
zinc
67
TNF
59
calcium
52
serine
42
water
39
MDA
34
glucose
33
nitric oxide
30
THP
29
THP
29
leucine
28
NH2
27
MTT
26
tyrosine
26
sodium
25
arginine
24
alanine
24
sulfate
23
Gly
23
lysine
22
cysteine
21
EDTA
20
Collagenase
20
EDTA
20
SDS
19
cAMP
18
PMA
15
Asp
15
Phe
15
threonine
14
PMA
14
phosphate
13
methionine
13
Cereb
13
His
12
more...