Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.24.35 (matrix metalloproteinase 9)
 2,207 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
integrin, alpha 8 13.8
VICKZ2 13.8
matrix metalloproteinase 9 13.8
Nucleosome-binding protein 1 13.8
Adenylyl cyclase-associated protein 12.8
GCP-1 11.8
ZNT4 11.5
type I collagen alpha 1 chain 11.5
MID1IP1 11.5
matrix metalloproteinase 2 11.4
metalloelastase 11.4
ZNT6 11.2
N-acetylneuraminate pyruvate lyase 11.2
PLGL 11.1
HuP1 11.0
Metalloelastase 11.0
alpha-2-macroglobulin receptor 10.8
zinc transporter 5 10.8
heterogeneous nuclear ribonucleoprotein A3 10.8
MMP9 10.8
tissue inhibitor of metalloproteinase 1 10.8
Matrix metalloproteinase 9 10.7
Laminin subunit beta-3 10.6
matrilysin 10.4
granulocyte chemotactic protein-2 10.4
Kruppel-like factor 8 10.4
Type XIV collagen 10.4
protein tyrosine phosphatase receptor type C 10.4
LYNX1 10.4
TIMP metallopeptidase inhibitor 1 10.2
CX3CL1 protein 10.2
GCP-2 10.2
ZNT7 10.1
selectin P 10.1
stromelysin 10.1
MPP-9 10.1
Extracellular matrix protein 1 10.1
matrix metalloproteinase 10 10.0
Chitinase-3-like protein 1 10.0
bone marrow stromal cell antigen 1 10.0
collagenase-3 10.0
nuclear receptor coactivator 5 9.9
normal epithelial cell-specific 1 9.9
Alpha-L-fucosidase 9.8
BTG1 protein 9.8
PFDN1 9.8
stromelysin-3 9.8
CNK1 9.6
paternally expressed gene 1 9.6
epilysin 9.6
PSTK 9.6
kallikrein-related peptidase 4 9.6
tissue inhibitor of metalloproteinases 9.5
KLRD1 9.5
Tissue inhibitor of metalloproteinase 1 9.4
PRS II 9.4
TIMP-2 9.4
JFC1 9.4
TRAF-3 9.4
MMP-9 9.3
matrix metalloproteinase 1 9.3
calcyphosine 9.3
metalloproteinase 1 9.3
Supervillin 9.3
MMP-3 9.3
TIMP 9.3
MMP-26 9.2
metastasis-related protein 9.2
osteoclast-associated receptor 9.2
MMP-1 9.1
RAB27B 9.1
secretory leukocyte peptidase inhibitor 9.1
mitogen-activated protein kinase 6 9.1
LCN2 protein 9.1
clone 10 9.1
beta B1-crystallin 9.1
FXYD5 9.1
RLN2 9.0
B2t 9.0
PTPE 9.0
TOP3B 8.9
DAAM2 8.9
orosomucoid 1 8.9
KLRK1 8.9
MMP8 8.9
SEMA5A 8.8
RECK protein 8.8
MMP-7 8.8
neurofilament-light 8.8
tissue inhibitor of metalloproteinases-2 8.8
CDH5 8.8
TIMP-3 8.7
prorelaxin 8.7
insulysin 8.7
Necl-4 8.7
MMP 8.7
MMP-8 8.7
JKTBP1 8.6
keratin K5 8.6
Angiopoietin 2 8.6
cytoskeleton-associated protein 4 8.6
ribosomal protein P0 8.6
MMP-2 8.6
IL32 8.6
ADAM10 protein 8.5
Asef 8.5
matrix metalloproteinase 3 8.5
calgranulin C 8.5
MAP2 protein 8.5
KLRB1 8.5
ADAMTS20 8.5
B3.1 8.5
nephronectin 8.5
cathepsin K 8.5
mucin 5AC 8.4
SELE 8.4
HGK 8.4
ribophorin II 8.4
MMP-19 8.4
VEGFA protein 8.4
Complement component C3 8.4
Arylsulfatase B 8.4
C-X-C motif chemokine 5 8.4
Fibroblast growth factor 8 8.4
MMP-11 8.4
fatty acid 2-hydroxylase 8.4
epithelial membrane protein 8.4
TPD52 8.4
RPN2 8.4
Toll-like receptor 1 8.3
MMP-12 8.3
ADNP 8.3
ICAM-5 8.2
MMP-28 8.2
alpha1(I) procollagen 8.2
ITGB5 8.2
small nucleolar RNA host gene 12 8.2
bullous pemphigoid antigen 2 8.2
Angiopoietin 1 8.2
MMP-10 8.2
matrix metalloproteinase 8.2
HIN-1 8.2
metalloproteinase 8.1
FOXD2 8.1
immunoglobulin kappa chain 8.1
inhibitor of DNA binding 2 8.1
Ste24p 8.1
triggering receptor expressed on myeloid cells 1 8.1
IL16 8.1
MMP-13 8.1
Eosinophil-derived neurotoxin 8.1
ALKBH3 8.0
peroxiredoxin 4 8.0
filamin B 8.0
PLAU 8.0
CTSK 8.0
olfactomedin 4 7.9
B- and T-lymphocyte attenuator 7.9
HBE1 7.9
tropomyosin 1 7.9
more...
Disease
Corticosteroid-induced glaucoma 11.8
Cytotoxic edema 10.0
Fowl cholera 9.6
Stromal keratitis 9.6
MYP3 9.4
Elastolysis 9.4
chronic nasopharyngitis 9.4
Microinvasive 8.7
tooth resorption 8.2
Cardiac autonomic neuropathy 7.9
Lymphatic metastasis 7.9
West Nile encephalitis 7.6
cerebral degeneration 7.5
Transient cerebral ischemia 7.3
Alveolar bone loss 7.2
Pseudopregnancy 7.2
cough variant asthma 7.1
Middle cerebral artery occlusion 7.1
Malignant glioma 7.0
Fungal keratitis 6.8
Epidermolysis bullosa acquisita 6.7
Granuloma annulare 6.7
Diabetic complications 6.6
Infantile hemangioma 6.6
salivary gland cancer 6.5
Squamous Cell Carcinoma 6.5
Streptococcus pneumoniae meningitis 6.5
erythroplakia 6.5
Lyme arthritis 6.4
Breast carcinoma 6.4
metastatic osteosarcoma 6.4
Papillomas 6.3
tympanosclerosis 6.2
Acute Stroke 6.1
Renovascular hypertension 6.0
Hypertrophic 6.0
Complex regional pain syndrome 6.0
brain edema 5.9
papillary serous carcinoma 5.9
squamous cell carcinoma of the skin 5.9
PARK7 5.8
fibrosarcoma 5.7
embryonal tumor 5.7
metastatic bladder cancer 5.7
causalgia 5.6
Giant cell tumor of bone 5.6
autoimmune lymphoproliferative syndrome 5.6
Urbach 5.4
body lice 5.4
Angiostrongylus cantonensis 5.4
pancreatic fibrosis 5.4
Cerebral malaria 5.4
scleritis 5.4
cancer relapse 5.4
erythroblastosis 5.3
Bielschowsky 5.3
HGF 5.3
Granuloma 5.3
monocytic leukemia 5.3
MSS 5.3
premature rupture of membranes 5.2
infiltrating ductal carcinoma 5.2
PNET 5.2
enchondroma 5.2
pemphigoid 5.2
Renal fibrosis 5.2
renal clear cell carcinoma 5.1
plexiform neurofibroma 5.1
tumor angiogenesis 5.1
Heymann nephritis 5.1
hydrosalpinx 5.0
Osteosarcoma 5.0
Osteosarcoma 5.0
Allergic asthma 5.0
Tick-borne encephalitis 4.9
Angiosarcoma 4.9
Friend leukemia 4.8
pulmonary fibrosis 4.8
metastatic colon cancer 4.8
Deep vein thrombosis 4.8
cholesterolemia 4.8
Dermal 4.8
metastatic gastric cancer 4.8
inflammatory joint disease 4.8
hypercortisolemia 4.7
Staphylococcus aureus infection 4.7
LDLR 4.7
chondromatosis 4.7
villonodular synovitis 4.7
mastocytoma 4.6
vascular obstruction 4.6
macrocytic anemia 4.6
astrocytoma 4.6
hyperphenylalaninemia 4.6
kidney tumor 4.6
secondary AML 4.6
pulpitis 4.5
juvenile periodontitis 4.5
head lice 4.5
osteodystrophy 4.5
primitive neuroectodermal tumor 4.5
epithelial tumor 4.5
ATRX 4.5
renal osteodystrophy 4.4
abdominal aortic aneurysm 4.4
bacterial meningitis 4.4
coronary artery aneurysm 4.4
biliary tract cancer 4.4
lung metastases 4.4
tumor progression 4.4
inflammatory breast cancer 4.4
liver fibrosis 4.4
AIDS dementia complex 4.4
idiopathic pulmonary fibrosis 4.4
osteosarcoma 4.4
PNET 4.3
keratoacanthoma 4.3
HNSCC 4.3
ERS 4.3
MCS 4.3
bronchioloalveolar carcinoma 4.3
MCS 4.3
AGS 4.3
pseudoxanthoma elasticum 4.3
meningococcal meningitis 4.3
COL2A1 4.3
residual cancer 4.2
Medulloblastoma 4.2
PDR 4.2
Neuromyelitis optica 4.2
borreliosis 4.2
primitive neuroectodermal tumor 4.2
relapsing fever 4.2
Neoplasms 4.2
DWI 4.1
choriocarcinoma 4.1
Harada 4.1
lentigo 4.1
mammary tumor 4.1
Kawasaki disease 4.1
external ear 4.1
PND 4.1
MIP 4.1
cholesteatoma 4.1
keratitis 4.1
chorioamnionitis 4.1
DM2 4.1
EDC 4.1
intracranial aneurysm 4.1
histiocytic lymphoma 4.0
MDI 4.0
metritis 4.0
acute monocytic leukemia 4.0
MAR 4.0
odontogenic tumor 4.0
tumor growth 4.0
B-cell chronic lymphocytic leukemia 4.0
HAM 4.0
renal hypertension 4.0
Blocking 4.0
more...
Symptom
Central post-stroke pain 9.0
impaired motor coordination 6.2
swollen joints 5.8
functional recovery 3.6
dry eye 3.5
hyperoxia 3.1
chronic cough 2.8
skin irritation 2.7
thinning 2.7
respiratory distress 1.9
acute stress 1.6
splenomegaly 1.5
hypothermia 1.3
spasm 1.0
dystonia 0.8
dizziness 0.6
angina 0.4
starvation 0.2
erythema 0.1
analgesia 0.0
collapse 0.0
ataxia -0.1
chest pain -0.3
anesthesia -0.3
pain -0.7
cough -0.7
overweight -0.9
seizures -0.9
abdominal pain -1.1
weakness -1.4
headache -2.0
Drug
Liarozole fumarate 11.8
Trocade 11.2
Prinomastat 9.6
Batimastat 9.3
Batimastat 9.3
Avasimibe 9.2
Ilomastat 8.6
Prolastin 8.5
Gelatin 8.5
Oxaprozin 7.9
Hyoscyamine 7.8
Fennel 7.8
Marimastat 7.6
Lacidipine 7.1
Trilostane 7.0
Lacidipine 6.8
Aliskiren 6.8
Hyperforin 6.8
Eptifibatide 6.7
ID2 6.7
uPA 6.4
Artemether 6.3
Argatroban 6.0
Magnesium sulfate 5.8
Doxycycline 5.7
Ketotifen 5.6
Urokinase 5.5
Rutin 5.5
CTT 5.1
Cilostazol 5.1
Emodin 4.9
Amiloride 4.8
Simvastatin 4.7
Emodin 4.6
BTC 4.6
Amiloride 4.6
Glide 4.5
PDL 4.5
Rosiglitazone 4.2
Methylprednisolone 4.0
Monensin 3.9
IFN-beta 3.8
Propofol 3.8
AraC 3.8
Vitamin E 3.7
Lactose 3.7
DNase I 3.6
TAT 3.6
Indomethacin 3.5
p75 3.5
Pronase 3.5
ZnCl2 3.5
ZnCl2 3.5
G-CSF 3.5
PTH 3.4
IL-1ra 3.4
Gleevec 3.3
Prednisolone 3.3
Bortezomib 3.3
Bevacizumab 3.0
NaI 3.0
NaI 3.0
NaI 3.0
NaI 3.0
Fructose 2.9
-deoxyadenosine 2.8
CaCl2 2.8
CaCl2 2.8
EPI 2.8
Gel 2.8
CaCl2 2.7
Paraffin 2.7
MDS 2.7
Captopril 2.7
Asn 2.6
CSF 2.6
Imatinib 2.5
IFN-gamma 2.5
Alliance 2.4
AZT 2.4
ETA 2.4
Rituximab 2.3
Growth hormone 2.3
AZT 2.2
Growth hormone 2.2
MAP 2.2
ADM 2.2
ROS 2.2
Retinoic acid 2.1
MRC 2.1
PCP 2.0
Angiotensin II 1.5
ICI 1.4
CTX 1.4
CTX 1.3
vitamin E 1.3
lysine 1.3
Asthma 1.2
EPA 1.0
Dermatol 0.9
ROC 0.9
lactose 0.8
ABC 0.7
nitroglycerin 0.7
CTX 0.5
TiO2 0.4
IL-2 -0.0
Leaf -0.6
ascorbate -0.7
Cardiovasc -1.0
Monit -1.3
Enzyme
matrix metalloproteinase 9 13.8
matrix metalloproteinase 2 11.9
galactose-6-sulfatase 11.5
collagenase 3 11.0
macrophage elastase 10.7
interstitial collagenase 10.7
matrix metalloproteinase 10 10.3
neutrophil collagenase 10.2
stromelysin-3 10.2
matrilysin-2 9.5
MMP-3 9.5
deuterolysin 9.3
MMP 9.1
cathepsin K 8.5
IgA protease 7.9
adamalysin 7.5
collagenase 7.5
NADPH:quinone oxidoreductase 7.5
hydroxyprostaglandin dehydrogenase 7.2
pantetheinase 7.0
cathepsin G 7.0
glycoprotease 6.9
hatching enzyme 6.8
IgA1 protease 6.7
neutrophil elastase 6.7
urokinase-type plasminogen activator 6.5
chondroitin ABC lyase 6.3
histidyl-tRNA synthetase 6.3
chymase 6.2
TACE 6.2
PIP kinase 6.2
pregnancy-associated plasma protein-A 6.1
aminopeptidase P 6.1
ancrod 6.0
plasmin 5.9
cathepsin S 5.9
isopeptidase 5.7
proline dehydrogenase 5.5
elastase 5.5
matriptase 5.3
tissue plasminogen activator 5.3
TSP-1 5.1
cathepsin B 5.0
matriptase 4.8
cathepsin D 4.8
meprin 4.7
tryptase 4.7
arylsulfatase A 4.5
thermolysin 4.5
endothelin-converting enzyme 4.5
cathepsin L 4.5
phosphatidylinositol 4-kinase 4.4
mu-calpain 4.4
type III procollagen 4.4
CD13 4.3
alanine aminopeptidase 4.3
insulin-degrading enzyme 4.3
PNGase F 4.2
MCS 4.2
TMT 4.2
m-calpain 4.1
CD10 4.1
MIP 4.1
phosphoinositide 3-kinase 4.1
acid phosphatase 4.1
12-lipoxygenase 4.1
mitogen-activated protein kinase 4.1
p100 4.0
Pla 4.0
prostaglandin synthetase 4.0
3beta-hydroxysteroid dehydrogenase 4.0
carboxypeptidase A 3.9
diacylglycerol kinase 3.9
BAL 3.9
isocitrate dehydrogenase 3.8
proprotein convertase 3.7
granzyme B 3.7
trypsin 3.7
MEK 3.7
isocitrate dehydrogenase 3.6
TAT 3.6
arylsulfatase 3.6
luciferase 3.6
NADPH oxidase 3.5
PKG 3.5
NADPH oxidase 3.5
histone acetyltransferase 3.4
histidine decarboxylase 3.3
DAT 3.3
AST 3.3
triphosphatase 3.2
phosphatidylinositol 3-kinase 3.2
furin 3.2
PAL 3.2
leucine aminopeptidase 3.1
IKK 3.1
aldose reductase 3.1
PTA 3.1
GSK 3.1
aconitase 3.0
tryptophan hydroxylase 3.0
caspase-3 3.0
prolyl hydroxylase 3.0
ERK 3.0
phosphorylase 2.9
focal adhesion kinase 2.9
beta-glucuronidase 2.9
protein kinase C 2.9
NO synthase 2.9
kallikrein 2.8
NQO1 2.8
PAL 2.8
chitinase 2.8
superoxide dismutase 2.7
peroxidase 2.7
chondroitinase 2.7
ribonuclease 2.7
glutathione peroxidase 2.7
ribonuclease 2.7
soluble epoxide hydrolase 2.7
PDK1 2.7
citrate synthase 2.7
reverse transcriptase 2.6
carbonic anhydrase 2.5
chloramphenicol acetyltransferase 2.5
catalase 2.4
aspartate aminotransferase 2.4
chymotrypsin 2.4
thrombin 2.4
calcineurin 2.3
glucokinase 2.3
protein kinase 2.3
alkaline phosphatase 2.3
protein phosphatase 2A 2.3
transcriptase 2.2
sulfatase 2.2
RNase 2.1
PARP 2.1
caspase-8 2.1
HSD 2.1
pyruvate dehydrogenase 2.1
prostate-specific antigen 2.1
pyruvate dehydrogenase 2.0
RNase 2.0
proteasome 2.0
NOS 2.0
S1 nuclease 2.0
enolase 2.0
arginase 2.0
caspase-9 1.9
PCP 1.9
alanine aminotransferase 1.9
DNase 1.9
CaMKII 1.8
MDR 1.7
malate dehydrogenase 1.7
transglutaminase 1.6
beta-galactosidase 1.6
tyrosine hydroxylase 1.6
pyruvate dehydrogenase 1.4
more...
Compound
C21H19NO4S 12.8
C21H19NO4S 12.8
C21H19NO4S 12.8
C21H19NO4S 12.2
C5H10N2O2 12.2
Pseurotin A 11.2
CEPC 11.0
Gossypin 10.4
Butin 10.2
Pectolinarigenin 10.1
Methacycline 10.1
27-Hydroxycholesterol 9.6
Oxaprozin 8.4
Malvidin 8.4
Collagenase 8.2
Brazilin 8.1
DT3 8.0
thiirane 7.9
Benztropine 7.8
Escin 7.6
Escin 7.5
p-Cymene 7.4
Sesamin 7.3
Esculin 7.1
TCTP 7.1
Palmitoylethanolamide 7.0
Embelin 7.0
erythrodiol 7.0
Matrine 6.9
Matrine 6.9
Matrine 6.9
Indirubin 6.9
Hyperforin 6.8
CD 3 6.7
S-methylcysteine 6.7
Coomassie Brilliant Blue G 6.7
prostaglandin J2 6.6
Palmitoleic acid 6.5
TTNPB 6.5
NEU 6.5
Phorbol-12-myristate-13-acetate 6.5
Fluvastatin 6.5
Isoliquiritigenin 6.5
Nobiletin 6.3
Ginsenoside Rg1 6.3
PGJ2 6.2
Cinnamic acid 6.2
TACE 6.2
Eplerenone 6.1
Magnolol 6.1
Tauroursodeoxycholic acid 6.1
Argatroban 6.0
Chelerythrine 6.0
Chelerythrine 6.0
Plumbagin 6.0
Formoterol 5.9
Pepstatin 5.9
Fisetin 5.8
Shikonin 5.8
Doxycycline 5.7
Magnesium sulfate 5.7
Leupeptin 5.7
Miconazole 5.7
Montelukast 5.7
Paeoniflorin 5.6
Magnesium sulfate 5.6
Edaravone 5.5
Keratin 5.5
Celastrol 5.5
Phorbol 12-myristate 13-acetate 5.4
ADMA 5.4
Phalloidin 5.4
Clotrimazole 5.4
Sevoflurane 5.3
Leupeptin 5.3
THP 5.3
DHB 5.3
THP 5.3
NMA 5.3
HEI 5.3
HFIP 5.3
Ursolic acid 5.2
Plasmin 5.2
Ellagic acid 5.2
Pioglitazone 5.2
Probucol 5.1
norvaline 5.1
HCP 5.0
SP-1 5.0
norvaline 5.0
His-Leu 5.0
Rutin 5.0
Vanillin 4.9
SCC 4.9
Crocin 4.9
Minocycline 4.9
Emodin 4.9
Baicalein 4.9
Naringin 4.9
MCP 4.9
Triptolide 4.9
Levetiracetam 4.8
Amiloride 4.8
MPT 4.8
ASN 4.8
HCP 4.8
Triiodothyronine 4.7
LPR 4.7
PMA 4.7
protocatechuate 4.7
CMK 4.6
T13 4.6
Phytic acid 4.6
BTC 4.6
Toluidine blue 4.6
Isoform 4.6
Cytochalasin D 4.6
pentosidine 4.5
Bisulfite 4.5
Hemin 4.5
Hemin 4.5
Hemin 4.5
Hemin 4.5
Vimentin 4.5
Homocysteine 4.5
Homocysteine 4.5
DFO 4.5
Methylglyoxal 4.4
Gb3 4.4
celastrol 4.4
Acrolein 4.4
Phorbol 4.4
Pro-Gly 4.4
Dichloroacetate 4.4
Hemin 4.4
PMSF 4.3
MDA 4.3
MNNG 4.3
Tiron 4.3
DIM 4.3
bis(2-chloroethyl) 4.3
Lycopene 4.3
Ang II 4.2
IBA 4.2
ENU 4.2
TPA 4.2
TNM 4.2
Azole 4.2
PMA 4.1
IPA 4.1
Collagen 4.1
MAD 4.1
IPA 4.1
IPA 4.1
Serine 4.1
Methylprednisolone 4.1
IPA 4.1
Hematoxylin 4.1
AAT 4.1
CAN 4.0
more...